Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for nkx1.2la

Z-value: 0.38

Motif logo

logo of

Transcription factors associated with nkx1.2la

Gene Symbol Gene ID Gene Info
nkx1.2la
ENSDARG00000006350 NK1 transcription factor related 2-like,a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx1.2ladr11_v1_chr13_+_40770628_40770628-0.302.2e-01Click!

Activity profile of nkx1.2la motif

Sorted Z-values of nkx1.2la motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_7421898 1.07 ENSDART00000043946
ccdc65
coiled-coil domain containing 65
chr23_+_19813677 0.96 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr2_-_38000276 0.89 ENSDART00000034790
pcp4l1
Purkinje cell protein 4 like 1
chr9_-_41062412 0.76 ENSDART00000193879
ankar
ankyrin and armadillo repeat containing
chr1_-_17715493 0.71 ENSDART00000133027
si:dkey-256e7.8
si:dkey-256e7.8
chr23_+_12134839 0.60 ENSDART00000128551
ENSDART00000141204
ttll9
tubulin tyrosine ligase-like family, member 9
chr4_-_9891874 0.57 ENSDART00000067193
adm2a
adrenomedullin 2a
chr3_-_39180048 0.52 ENSDART00000049720
cdk21
cyclin-dependent kinase 21
chr11_-_30634286 0.52 ENSDART00000191019
zgc:153665
zgc:153665
chr11_-_2838699 0.48 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr1_-_19502322 0.46 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr22_-_35330532 0.44 ENSDART00000172654
FO818743.1

chr21_-_43015383 0.42 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr5_-_68074592 0.37 ENSDART00000165052
ENSDART00000018792
spag7
sperm associated antigen 7
chr1_+_33668236 0.37 ENSDART00000122316
ENSDART00000102184
arl13b
ADP-ribosylation factor-like 13b
chr15_-_5815006 0.35 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr19_+_31873308 0.35 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
si:dkeyp-34f6.4
chr8_-_53044300 0.34 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr6_-_40842768 0.32 ENSDART00000076160
mustn1a
musculoskeletal, embryonic nuclear protein 1a
chr7_+_6652967 0.32 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr6_-_7720332 0.32 ENSDART00000135945
rpsa
ribosomal protein SA
chr8_+_16025554 0.32 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr15_-_35134918 0.31 ENSDART00000157196
si:ch211-272b8.7
si:ch211-272b8.7
chr4_+_11723852 0.30 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr21_+_45223194 0.29 ENSDART00000150902
si:ch73-269m14.3
si:ch73-269m14.3
chr4_+_16885854 0.29 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr12_+_695619 0.28 ENSDART00000161691
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr20_+_19512727 0.27 ENSDART00000063696
atraid
all-trans retinoic acid-induced differentiation factor
chr20_-_9095105 0.26 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr21_-_19314618 0.25 ENSDART00000188744
gpat3
glycerol-3-phosphate acyltransferase 3
chr10_-_5847655 0.25 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr5_+_69747417 0.25 ENSDART00000153717
si:ch211-275j6.5
si:ch211-275j6.5
chr16_-_30434279 0.25 ENSDART00000018504
zgc:77086
zgc:77086
chr21_+_6751405 0.25 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr24_-_31425799 0.24 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr11_+_30057762 0.24 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr5_-_25723079 0.23 ENSDART00000014013
gda
guanine deaminase
chr7_+_59020972 0.23 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr2_-_20788698 0.22 ENSDART00000181823
CABZ01020455.1

chr21_+_6751760 0.21 ENSDART00000135914
olfm1b
olfactomedin 1b
chr5_-_22969424 0.21 ENSDART00000143869
ENSDART00000172549
si:dkey-237j10.2
si:dkey-237j10.2
chr12_+_47698356 0.21 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr11_+_16153207 0.20 ENSDART00000192356
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr3_+_54744069 0.20 ENSDART00000134958
ENSDART00000114443
si:ch211-74m13.3
si:ch211-74m13.3
chr13_+_35339182 0.20 ENSDART00000019323
jag1b
jagged 1b
chr4_+_9669717 0.19 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr17_-_12385308 0.18 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr8_+_17168114 0.18 ENSDART00000183901
cenph
centromere protein H
chr18_+_17827149 0.18 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr15_+_9327252 0.18 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr11_+_16152316 0.18 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr11_+_705727 0.17 ENSDART00000165366
timp4.2
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr15_+_15856178 0.17 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr8_+_18588551 0.17 ENSDART00000177476
ENSDART00000063539
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr17_+_21964472 0.16 ENSDART00000063704
ENSDART00000188904
crip3
cysteine-rich protein 3
chr4_+_6032640 0.16 ENSDART00000157487
tfec
transcription factor EC
chr20_-_47188966 0.16 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr1_-_50859053 0.16 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr7_+_34620418 0.16 ENSDART00000081338
slc9a5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr8_-_53044089 0.15 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr5_+_66433287 0.15 ENSDART00000170757
kntc1
kinetochore associated 1
chr25_+_11008419 0.15 ENSDART00000156589
mhc1lia
major histocompatibility complex class I LIA
chr11_-_21528056 0.14 ENSDART00000181626
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr15_+_23799461 0.14 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr23_-_37575030 0.14 ENSDART00000031875
tor1l3
torsin family 1 like 3
chr25_+_29160102 0.13 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr5_+_36870737 0.13 ENSDART00000145182
slc8a2a
solute carrier family 8 (sodium/calcium exchanger), member 2a
chr8_+_52637507 0.13 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr3_-_12930217 0.12 ENSDART00000166322
pdgfab
platelet-derived growth factor alpha polypeptide b
chr10_-_40968095 0.12 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr22_+_9939901 0.12 ENSDART00000169777
ENSDART00000081420
zgc:171686
zgc:171686
chr17_-_49978986 0.12 ENSDART00000154728
col12a1a
collagen, type XII, alpha 1a
chr5_+_22969651 0.12 ENSDART00000089992
ENSDART00000145477
hmgn7
high mobility group nucleosomal binding domain 7
chr25_+_20715950 0.12 ENSDART00000180223
ergic2
ERGIC and golgi 2
chr11_+_2506516 0.11 ENSDART00000130886
ENSDART00000189767
NABP2
si:ch73-190f16.2
chr14_-_413273 0.11 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr20_+_28861435 0.11 ENSDART00000142678
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr18_+_21408794 0.11 ENSDART00000140161
necab2
N-terminal EF-hand calcium binding protein 2
chr1_-_31171242 0.11 ENSDART00000190294
kcnq5b
potassium voltage-gated channel, KQT-like subfamily, member 5b
chr8_+_25079470 0.11 ENSDART00000000744
sypl2b
synaptophysin-like 2b
chr4_-_3353595 0.10 ENSDART00000009076
pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr7_+_34453185 0.10 ENSDART00000173875
ENSDART00000173921
ENSDART00000173995
si:cabz01009626.1
si:cabz01009626.1
chr22_-_26865181 0.10 ENSDART00000138311
hmox2a
heme oxygenase 2a
chr11_-_29737088 0.10 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr4_+_77943184 0.10 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr15_-_30505607 0.09 ENSDART00000155212
msi2b
musashi RNA-binding protein 2b
chr16_-_20312146 0.08 ENSDART00000134980
si:dkeyp-86h10.3
si:dkeyp-86h10.3
chr11_-_30158191 0.08 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr9_+_35015747 0.08 ENSDART00000140110
gabpa
GA binding protein transcription factor, alpha subunit
chr24_-_21689146 0.08 ENSDART00000105917
urad
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr21_-_45363871 0.08 ENSDART00000075443
ENSDART00000182078
ENSDART00000151106
PPP2CA
zgc:56064
chr23_+_28582865 0.08 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr22_-_5252005 0.08 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr6_+_28051978 0.08 ENSDART00000143218
si:ch73-194h10.2
si:ch73-194h10.2
chr1_-_7970653 0.08 ENSDART00000188909
si:dkey-79f11.7
si:dkey-79f11.7
chr23_-_15216654 0.07 ENSDART00000131649
sulf2b
sulfatase 2b
chr4_+_9400012 0.07 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr22_-_20011476 0.07 ENSDART00000093312
ENSDART00000093310
celf5a
cugbp, Elav-like family member 5a
chr16_+_23975930 0.07 ENSDART00000147858
ENSDART00000144347
ENSDART00000115270
apoc4
apolipoprotein C-IV
chr10_+_37137464 0.06 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr16_-_11798994 0.06 ENSDART00000135408
cnfn
cornifelin
chr22_-_8725768 0.06 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
si:ch73-27e22.1
si:ch73-27e22.8
chr20_+_28861629 0.06 ENSDART00000187274
ENSDART00000047826
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr23_+_16815353 0.06 ENSDART00000142789
ENSDART00000143424
zgc:100832
zgc:100832
chr4_+_21129752 0.05 ENSDART00000169764
syt1a
synaptotagmin Ia
chr18_-_16924221 0.05 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr8_-_39822917 0.05 ENSDART00000067843
zgc:162025
zgc:162025
chr25_+_19489370 0.05 ENSDART00000091132
glsl
glutaminase like
chr23_-_1660708 0.05 ENSDART00000175138
CU693481.1

chr19_+_46158078 0.05 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr4_+_57583139 0.04 ENSDART00000158802
il17ra1b
interleukin 17 receptor A1b
chr14_+_5385855 0.04 ENSDART00000031508
lbx2
ladybird homeobox 2
chr24_+_38301080 0.04 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr16_-_31622777 0.04 ENSDART00000137311
ENSDART00000002930
phf20l1
PHD finger protein 20 like 1
chr4_+_20566371 0.03 ENSDART00000127576
BX248410.1

chr6_+_57541776 0.03 ENSDART00000157330
necab3
N-terminal EF-hand calcium binding protein 3
chr15_-_14552101 0.03 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr16_+_23984179 0.02 ENSDART00000175879
apoc2
apolipoprotein C-II
chr5_-_51619742 0.02 ENSDART00000188537
otpb
orthopedia homeobox b
chr21_+_16145980 0.02 ENSDART00000135119
qrfpr4
pyroglutamylated RFamide peptide receptor 4
chr23_+_43255328 0.02 ENSDART00000102712
tgm2a
transglutaminase 2, C polypeptide A
chr13_-_37229245 0.02 ENSDART00000140923
si:dkeyp-77c8.5
si:dkeyp-77c8.5
chr1_+_44127292 0.02 ENSDART00000160542
cabp2a
calcium binding protein 2a
chr6_+_40832635 0.01 ENSDART00000011931
ruvbl1
RuvB-like AAA ATPase 1
chr17_-_10122204 0.01 ENSDART00000160751
BX088587.1

chr13_-_9886579 0.01 ENSDART00000101926
si:ch211-117n7.7
si:ch211-117n7.7
chr14_+_40874608 0.01 ENSDART00000168448
si:ch211-106m9.1
si:ch211-106m9.1
chr18_+_24919614 0.01 ENSDART00000008638
rgma
repulsive guidance molecule family member a
chr19_+_2631565 0.01 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr4_-_45115963 0.01 ENSDART00000137248
si:dkey-51d8.6
si:dkey-51d8.6
chr10_+_35358675 0.00 ENSDART00000193263
si:dkey-259j3.5
si:dkey-259j3.5
chr16_+_23976227 0.00 ENSDART00000193013
apoc4
apolipoprotein C-IV
chr19_+_12237945 0.00 ENSDART00000190034
grhl2b
grainyhead-like transcription factor 2b
chr14_-_4556896 0.00 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr5_+_36611128 0.00 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx1.2la

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0003352 regulation of cilium movement(GO:0003352)
0.1 0.4 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.5 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0046415 allantoin metabolic process(GO:0000255) urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.5 GO:0060122 detection of mechanical stimulus involved in sensory perception(GO:0050974) inner ear receptor stereocilium organization(GO:0060122)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.0 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.6 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE