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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nfe2l1b+nfe2l2b

Z-value: 0.31

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Transcription factors associated with nfe2l1b+nfe2l2b

Gene Symbol Gene ID Gene Info
ENSDARG00000076533 nuclear factor, erythroid 2-like 1b
ENSDARG00000089697 nuclear factor, erythroid 2-like 2b
ENSDARG00000114820 nuclear factor, erythroid 2-like 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfe2l1bdr11_v1_chr12_+_28854410_288544100.282.6e-01Click!
nfe2l2bdr11_v1_chr6_-_10902916_109029160.204.2e-01Click!

Activity profile of nfe2l1b+nfe2l2b motif

Sorted Z-values of nfe2l1b+nfe2l2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_38750871 0.41 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
coagulation factor II (thrombin)
chr17_+_24684778 0.39 ENSDART00000146309
ENSDART00000082237
zinc finger protein 593
chr13_+_42676202 0.37 ENSDART00000099782
mitochondrial ribosomal protein L14
chr14_-_14659023 0.37 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr22_-_26865361 0.35 ENSDART00000182504
heme oxygenase 2a
chr10_+_42733210 0.35 ENSDART00000189832

chr24_-_37698796 0.34 ENSDART00000172178
si:ch211-231f6.6
chr11_+_7276983 0.32 ENSDART00000172407
ENSDART00000161176
ENSDART00000161041
ENSDART00000165536
si:ch73-238c9.1
chr24_-_10006158 0.31 ENSDART00000106244
zgc:171750
chr7_-_19600181 0.30 ENSDART00000100757
oxidase (cytochrome c) assembly 1-like
chr1_-_53880639 0.30 ENSDART00000010543
LTV1 ribosome biogenesis factor
chr6_+_6797520 0.29 ENSDART00000150967
si:ch211-85n16.3
chr5_-_9073433 0.29 ENSDART00000099891
ATP synthase membrane subunit eb
chr1_-_45320126 0.28 ENSDART00000133572
si:ch73-90k17.1
chr3_-_7656059 0.28 ENSDART00000170917
JunB proto-oncogene, AP-1 transcription factor subunit b
chr19_+_12350069 0.27 ENSDART00000052240
proteasome (prosome, macropain) assembly chaperone 2
chr14_+_81919 0.27 ENSDART00000171444
stromal antigen 3
chr23_-_14769523 0.27 ENSDART00000054909
glutathione synthetase
chr22_+_10201826 0.26 ENSDART00000006513
ENSDART00000132641
pyruvate dehydrogenase E1 beta subunit
chr20_-_52631998 0.26 ENSDART00000145283
ENSDART00000139072
si:ch211-221n20.1
chr1_+_26467071 0.26 ENSDART00000112329
ENSDART00000159318
ENSDART00000193833
ENSDART00000011809
USO1 vesicle transport factor
chr13_-_49819027 0.25 ENSDART00000067824
beta-1,3-N-acetylgalactosaminyltransferase 2
chr16_+_46205693 0.25 ENSDART00000058385
ENSDART00000168145
bolA family member 1
chr2_+_37207461 0.25 ENSDART00000138952
ENSDART00000132856
ENSDART00000137272
ENSDART00000143468
apolipoprotein Da, duplicate 2
chr9_-_3149896 0.23 ENSDART00000020861
pyruvate dehydrogenase kinase, isozyme 1
chr3_-_14695033 0.23 ENSDART00000133850
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr20_+_4793516 0.23 ENSDART00000053875
galectin 8a
chr18_-_43866001 0.23 ENSDART00000150218
trehalase (brush-border membrane glycoprotein)
chr2_+_8780443 0.22 ENSDART00000137768
zinc finger, ZZ-type containing 3
chr24_+_21346796 0.22 ENSDART00000126519
shisa family member 2b
chr18_-_41232297 0.22 ENSDART00000036928
F-box protein 36a
chr23_-_19827411 0.21 ENSDART00000187964
HAUS augmin-like complex, subunit 7
chr18_-_14274803 0.21 ENSDART00000166643
malonyl-CoA decarboxylase
chr18_-_43866526 0.21 ENSDART00000111309
trehalase (brush-border membrane glycoprotein)
chr9_-_1604601 0.21 ENSDART00000143130
alkylglycerone phosphate synthase
chr21_-_39604549 0.21 ENSDART00000161516
ENSDART00000151638
phosphatidylinositol glycan anchor biosynthesis, class S
chr20_-_23494695 0.20 ENSDART00000058524
ENSDART00000146203
anaphase promoting complex subunit 4
chr5_-_33274645 0.20 ENSDART00000188584
kynurenine aminotransferase 1
chr23_+_39695827 0.20 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr24_+_42149453 0.20 ENSDART00000128766
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr4_+_17539134 0.20 ENSDART00000013313
integrin alpha FG-GAP repeat containing 2
chr24_-_36136401 0.19 ENSDART00000193853
transmembrane protein 14Cb
chr11_+_44622472 0.19 ENSDART00000159068
ENSDART00000166323
ENSDART00000187753
RNA binding motif protein 34
chr25_-_28926330 0.19 ENSDART00000155173
electron transfer flavoprotein beta subunit lysine methyltransferase
chr5_+_69733096 0.18 ENSDART00000169013
ADP-ribosylation factor-like 6 interacting protein 4
chr16_-_49646625 0.18 ENSDART00000101629
EF-hand domain family, member B
chr5_+_69278089 0.18 ENSDART00000136656
selenoprotein M
chr6_-_10835849 0.18 ENSDART00000005903
ENSDART00000135065
ATP synthase membrane subunit c locus 3b
chr17_-_28707898 0.18 ENSDART00000135752
ENSDART00000061853
adaptor-related protein complex 4, sigma 1 subunit
chr21_+_1647990 0.18 ENSDART00000148540
ferrochelatase
chr12_-_13205854 0.18 ENSDART00000077829
pelota mRNA surveillance and ribosome rescue factor
chr8_+_27807974 0.18 ENSDART00000078509
capping protein (actin filament) muscle Z-line, alpha 1b
chr3_+_59411956 0.17 ENSDART00000166982
SEC14-like lipid binding 1
chr11_-_7355995 0.17 ENSDART00000156595
si:dkey-197i20.6
chr21_-_2958422 0.17 ENSDART00000174091
zgc:194215
chr10_-_17221725 0.17 ENSDART00000111088
DEP domain containing 5
chr18_+_2222447 0.17 ENSDART00000185927
PIGB opposite strand 1
chr20_-_40720458 0.17 ENSDART00000153151
ENSDART00000061261
ENSDART00000138569
connexin 43
chr22_+_3156386 0.17 ENSDART00000161212
ribosomal protein L36
chr2_+_37176814 0.17 ENSDART00000048277
ENSDART00000176827
coatomer protein complex, subunit alpha
chr6_+_15210072 0.17 ENSDART00000186232
NCK adaptor protein 2b
chr23_+_19675780 0.17 ENSDART00000124335
small integral membrane protein 4
chr23_+_34047413 0.17 ENSDART00000143933
ENSDART00000123925
ENSDART00000176139
coiled-coil-helix-coiled-coil-helix domain containing 6a
chr6_-_49526510 0.17 ENSDART00000128025
ribosomal protein S26, like
chr25_+_35134393 0.16 ENSDART00000185379

chr24_-_35561672 0.16 ENSDART00000058564
minichromosome maintenance complex component 4
chr21_-_5881344 0.16 ENSDART00000009241
ribosomal protein L35
chr1_-_10048514 0.16 ENSDART00000125358
ENSDART00000054835
ring finger protein 175
chr16_+_43368572 0.16 ENSDART00000032778
ENSDART00000193897
ring finger protein 144B
chr4_-_330748 0.16 ENSDART00000067488
mitochondrial ribosomal protein S10
chr8_-_40205712 0.16 ENSDART00000158927
anaphase promoting complex subunit 5
chr9_+_28688574 0.16 ENSDART00000101319
zgc:162396
chr11_+_7276824 0.16 ENSDART00000185992
si:ch73-238c9.1
chr14_-_24332786 0.16 ENSDART00000173164
family with sequence similarity 13, member B
chr10_+_14982977 0.15 ENSDART00000140869
si:dkey-88l16.3
chr19_-_10330778 0.15 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
coiled-coil domain containing 106b
chr14_-_16151055 0.15 ENSDART00000162431
pentatricopeptide repeat domain 3
chr2_+_11031360 0.15 ENSDART00000180020
ENSDART00000145093
acyl-CoA thioesterase 11a
chr12_-_13205572 0.15 ENSDART00000152670
pelota mRNA surveillance and ribosome rescue factor
chr7_-_37917517 0.15 ENSDART00000173795
HEAT repeat containing 3
chr15_-_17099560 0.15 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr5_-_30080332 0.14 ENSDART00000140049
beta-carotene oxygenase 2a
chr22_+_16097185 0.14 ENSDART00000165216
diphthamide biosynthesis 5
chr25_-_35139520 0.14 ENSDART00000189008

chr24_-_11905911 0.14 ENSDART00000033621
transmembrane 9 superfamily member 1
chr3_+_36284986 0.14 ENSDART00000059533
WD repeat domain, phosphoinositide interacting 1
chr7_-_41812355 0.14 ENSDART00000016105
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr22_+_18156000 0.14 ENSDART00000143483
ENSDART00000136133
nuclear receptor 2C2-associated protein
chr7_-_41812015 0.14 ENSDART00000174058
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr3_-_55511569 0.13 ENSDART00000108995
testis expressed 2
chr18_+_808911 0.13 ENSDART00000172518
cytochrome c oxidase subunit Vab
chr10_-_17222083 0.13 ENSDART00000134059
DEP domain containing 5
chr25_+_36347126 0.13 ENSDART00000152449
si:ch211-113a14.22
chr6_-_1432200 0.13 ENSDART00000182901

chr6_+_13201358 0.13 ENSDART00000190290

chr16_+_19033554 0.13 ENSDART00000182430
Rap guanine nucleotide exchange factor (GEF) 5b
chr2_+_43750899 0.13 ENSDART00000135836
Rho GTPase activating protein 12a
chr8_-_2506327 0.13 ENSDART00000101125
ENSDART00000125124
ribosomal protein L6
chr13_-_11971148 0.13 ENSDART00000066230
ENSDART00000185614
zgc:110197
chr4_-_5691257 0.13 ENSDART00000110497
transmembrane protein 63A
chr7_-_41915312 0.12 ENSDART00000159869
DnaJ (Hsp40) homolog, subfamily A, member 2
chr21_-_14815952 0.12 ENSDART00000134278
ENSDART00000067004
phosphohistidine phosphatase 1
chr13_+_4368504 0.12 ENSDART00000108935
SFT2 domain containing 1
chr4_-_77267787 0.12 ENSDART00000190346
zgc:174310
chr11_+_24900123 0.12 ENSDART00000044987
ENSDART00000148023
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr2_-_30135446 0.12 ENSDART00000141906
transient receptor potential cation channel, subfamily A, member 1a
chr16_+_10777116 0.12 ENSDART00000190902
ATPase Na+/K+ transporting subunit alpha 3b
chr12_-_28349026 0.12 ENSDART00000183768
ENSDART00000152998
zgc:195081
chr13_+_16279890 0.11 ENSDART00000101775
ENSDART00000057948
annexin A11a
chr13_-_38039871 0.11 ENSDART00000140645

chr9_-_52847881 0.11 ENSDART00000166407
transient receptor potential cation channel, subfamily M, member 2
chr6_+_515181 0.11 ENSDART00000171374
si:ch73-379f7.5
chr13_-_4223955 0.11 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr12_+_8074343 0.11 ENSDART00000124084
ciliary associated calcium binding coiled-coil 1
chr4_-_73447058 0.11 ENSDART00000172042
si:ch73-120g24.4
chr4_+_3482312 0.11 ENSDART00000109044
glutamate receptor, metabotropic 8a
chr12_+_6041575 0.11 ENSDART00000091868
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr4_-_73545626 0.11 ENSDART00000174295
si:ch73-266f23.1
chr12_-_3962372 0.11 ENSDART00000016791
eukaryotic translation initiation factor 3, subunit C
chr21_+_17768174 0.11 ENSDART00000141380
retinoid X receptor, alpha a
chr7_+_44593756 0.10 ENSDART00000125365
si:ch211-189a15.5
chr23_-_4915118 0.10 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr6_+_120181 0.10 ENSDART00000151209
ENSDART00000185930
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr8_-_13999293 0.10 ENSDART00000142098
si:dkeyp-110g5.4
chr3_-_58543658 0.10 ENSDART00000042386
un-named sa1261
chr13_+_25380432 0.10 ENSDART00000038524
glutathione S-transferase omega 1
chr5_+_41510387 0.10 ENSDART00000023779
valosin containing protein
chr19_-_32600823 0.10 ENSDART00000134149
ENSDART00000187858
zgc:91944
chr3_+_33300522 0.10 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr3_-_27647845 0.10 ENSDART00000151625
si:ch211-157c3.4
chr25_-_37322081 0.10 ENSDART00000128285
immunoglobulin light 4 variable 10
chr6_+_3809346 0.10 ENSDART00000185105

chr3_-_13147310 0.10 ENSDART00000160840
protein kinase, cAMP-dependent, regulatory, type I, beta
chr6_-_23931442 0.10 ENSDART00000160547
SEC16 homolog B, endoplasmic reticulum export factor
chr9_+_54686686 0.10 ENSDART00000066198
RAB9A, member RAS oncogene family
chr11_+_6882362 0.10 ENSDART00000144181
kelch-like family member 26
chr15_-_19334448 0.09 ENSDART00000062576
thymocyte nuclear protein 1
chr7_-_73815262 0.09 ENSDART00000185351
zgc:165555
chr13_-_17729474 0.09 ENSDART00000013011
voltage-dependent anion channel 2
chr5_-_33274943 0.09 ENSDART00000143435
ENSDART00000145222
ENSDART00000004797
kynurenine aminotransferase 1
chr14_+_20351 0.09 ENSDART00000051893
syntaxin 18
chr11_+_6009984 0.09 ENSDART00000185680
GTP binding protein 3, mitochondrial
chr3_-_55531450 0.09 ENSDART00000155376
testis expressed 2
chr2_+_9970942 0.09 ENSDART00000153063
SEC22 homolog B, vesicle trafficking protein a
chr3_-_13461361 0.09 ENSDART00000080807
F-box and WD repeat domain containing 9
chr10_-_1961576 0.09 ENSDART00000042441
teratocarcinoma-derived growth factor 1
chr1_+_26411496 0.09 ENSDART00000112263
Rho guanine nucleotide exchange factor (GEF) 38
chr2_-_32505091 0.09 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr17_+_27134806 0.09 ENSDART00000151901
ribosomal protein S6 kinase a, polypeptide 1
chr4_+_13412030 0.09 ENSDART00000003694
cullin-associated and neddylation-dissociated 1
chr23_-_24343363 0.08 ENSDART00000166392
family with sequence similarity 131, member C
chr19_+_20274264 0.08 ENSDART00000183513
oxidoreductase NAD-binding domain containing 1
chr4_+_5249494 0.08 ENSDART00000150391
si:ch211-214j24.14
chr20_-_3290791 0.08 ENSDART00000146870
si:ch1073-412h12.3
chr19_-_4010263 0.08 ENSDART00000159605
ENSDART00000165541
MAP7 domain containing 1b
chr21_+_25068215 0.08 ENSDART00000167523
ENSDART00000189259
DIX domain containing 1b
chr10_+_18877362 0.08 ENSDART00000138334
protein phosphatase 2, regulatory subunit B, alpha b
chr6_-_35446110 0.08 ENSDART00000058773
regulator of G protein signaling 16
chr4_+_3358383 0.08 ENSDART00000075320
nicotinamide phosphoribosyltransferase a
chr4_-_9592402 0.08 ENSDART00000114060
cerebral dopamine neurotrophic factor
chr14_+_33413980 0.08 ENSDART00000052780
ENSDART00000124437
ENSDART00000173327
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr3_-_34599662 0.08 ENSDART00000055259
nicotinamide riboside kinase 1
chr16_-_30864824 0.08 ENSDART00000190444
ENSDART00000192231
protein tyrosine kinase 2ab
chr8_-_50981175 0.07 ENSDART00000004065
zgc:91909
chr1_-_40086978 0.07 ENSDART00000136990
si:dkey-117m1.4
chr20_+_27331008 0.07 ENSDART00000141486
protein phosphatase 4, regulatory subunit 4
chr7_+_6969909 0.07 ENSDART00000189886
actinin alpha 3b
chr23_+_44049509 0.07 ENSDART00000102003
TXK tyrosine kinase
chr23_-_35790235 0.07 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
major facilitator superfamily domain containing 5
chr18_+_44673990 0.07 ENSDART00000018625
N-ethylmaleimide-sensitive factor attachment protein, alpha b
chr11_-_44622478 0.07 ENSDART00000171837
tubulin folding cofactor E
chr13_+_14006118 0.07 ENSDART00000131875
ENSDART00000089528
attractin
chr5_-_31856681 0.07 ENSDART00000187817
protein kinase N3
chr20_-_13765749 0.07 ENSDART00000133529
opsin 8, group member c
chr1_+_52137528 0.07 ENSDART00000007079
ENSDART00000074265
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr8_+_50983551 0.07 ENSDART00000142061
si:dkey-32e23.4
chr8_+_8012570 0.07 ENSDART00000183429
si:ch211-169p10.1
chr3_-_55139127 0.07 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr2_+_20496223 0.07 ENSDART00000157931
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a
chr5_+_35463688 0.07 ENSDART00000142525
ENSDART00000131286
ER lipid raft associated 2
chr13_+_19884631 0.07 ENSDART00000089533
attractin-like 1a
chr21_+_27278120 0.06 ENSDART00000193882
si:dkey-175m17.7
chr21_+_20901505 0.06 ENSDART00000132741
complement component 7b
chr6_+_15127507 0.06 ENSDART00000063644
diphthamide biosynthesis 3
chr7_-_5316901 0.06 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
chr18_+_38908903 0.06 ENSDART00000159834
myosin VAa
chr11_+_41936435 0.06 ENSDART00000173103
aldehyde dehydrogenase 4 family, member A1
chr21_-_16632808 0.06 ENSDART00000172645
unc-5 netrin receptor Da
chr24_+_9744012 0.06 ENSDART00000129656
transmembrane protein 108
chr3_-_32541033 0.06 ENSDART00000151476
ENSDART00000055324
reticulocalbin 3, EF-hand calcium binding domain
chr18_-_18584839 0.06 ENSDART00000159274
splicing factor 3b, subunit 3
chr6_-_13783604 0.06 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
crystallin, beta A2a
chr13_-_24669258 0.06 ENSDART00000000831
zinc finger protein 511
chr9_+_30626416 0.06 ENSDART00000147813
TBC1 domain family, member 4
chr5_-_23619911 0.06 ENSDART00000020004
myotubularin related protein 2
chr17_-_49481672 0.06 ENSDART00000166394
FCF1 rRNA-processing protein
chr7_-_49654492 0.06 ENSDART00000174324
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr13_+_10023256 0.06 ENSDART00000110035
S1 RNA binding domain 1
chr3_-_55128258 0.06 ENSDART00000101734
hemoglobin, alpha embryonic 1
chr2_+_27010439 0.06 ENSDART00000030547
cadherin 7a

Network of associatons between targets according to the STRING database.

First level regulatory network of nfe2l1b+nfe2l2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.3 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 0.2 GO:0097384 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.4 GO:0006953 acute-phase response(GO:0006953)
0.1 0.3 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.2 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 0.3 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.0 0.3 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.2 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.0 0.1 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.0 0.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0050961 thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
0.0 0.1 GO:0090008 hypoblast development(GO:0090008)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.1 GO:0070973 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0051131 proteasome assembly(GO:0043248) chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0035494 regulation of synaptic vesicle priming(GO:0010807) SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.0 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.0 GO:1902260 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.3 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.3 GO:0043295 glutathione binding(GO:0043295)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.1 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.0 0.1 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0072570 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.1 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.0 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.0 0.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA