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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nfe2

Z-value: 0.16

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Transcription factors associated with nfe2

Gene Symbol Gene ID Gene Info
ENSDARG00000020606 nuclear factor, erythroid 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfe2dr11_v1_chr23_-_36316352_36316352-0.428.4e-02Click!

Activity profile of nfe2 motif

Sorted Z-values of nfe2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_44804791 0.15 ENSDART00000122288
cathepsin La
chr5_+_44805028 0.15 ENSDART00000141198
cathepsin La
chr14_+_24840669 0.13 ENSDART00000106039
Rho guanine nucleotide exchange factor (GEF) 37
chr5_+_44805269 0.13 ENSDART00000136965
cathepsin La
chr17_+_32623931 0.12 ENSDART00000144217
cathepsin Ba
chr24_-_5691956 0.12 ENSDART00000189112
deleted in autism 1b
chr18_+_45571378 0.11 ENSDART00000077251
kinesin family member C3
chr14_+_3507326 0.11 ENSDART00000159326
glutathione S-transferase pi 1
chr4_-_1757460 0.11 ENSDART00000144074
transmembrane 7 superfamily member 3
chr13_+_42309688 0.11 ENSDART00000158367
insulin-degrading enzyme
chr18_-_2222128 0.09 ENSDART00000171402
phosphatidylinositol glycan anchor biosynthesis, class B
chr16_+_46410520 0.09 ENSDART00000131072
rapunzel 2
chr13_+_25397098 0.08 ENSDART00000132953
glutathione S-transferase omega 2
chr4_+_1757462 0.08 ENSDART00000032460
mediator complex subunit 21
chr1_-_40227166 0.08 ENSDART00000146680
si:ch211-113e8.3
chr21_-_929293 0.08 ENSDART00000006419
thioredoxin-like 1
chr13_+_25396896 0.08 ENSDART00000041257
glutathione S-transferase omega 2
chr2_-_6115688 0.08 ENSDART00000081663
peroxiredoxin 1
chr20_-_48604621 0.07 ENSDART00000161769
ENSDART00000157871
microsomal glutathione S-transferase 3a
chr25_+_33046060 0.07 ENSDART00000165345
talin 2b
chr5_+_42064144 0.07 ENSDART00000035235
si:ch211-202a12.4
chr23_+_25291891 0.07 ENSDART00000016248
proliferation-associated 2G4, b
chr15_+_40792667 0.07 ENSDART00000193186
ENSDART00000184559
FAT atypical cadherin 3a
chr21_-_929448 0.07 ENSDART00000133976
thioredoxin-like 1
chr20_-_48604199 0.07 ENSDART00000161762
ENSDART00000170894
microsomal glutathione S-transferase 3a
chr23_+_9508538 0.07 ENSDART00000010697
oxysterol binding protein-like 2b
chr6_-_1587291 0.06 ENSDART00000067592
ENSDART00000178877
zgc:123305
chr18_+_1703984 0.06 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr3_-_21280373 0.06 ENSDART00000003939
synaptogyrin 1a
chr16_+_13883872 0.06 ENSDART00000101304
ENSDART00000136005
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr17_+_33418475 0.06 ENSDART00000169145
synaptosomal-associated protein 23.1
chr2_-_6115389 0.06 ENSDART00000134921
peroxiredoxin 1
chr15_+_44283723 0.06 ENSDART00000167722
CWF19-like 2, cell cycle control (S. pombe)
chr11_-_29936755 0.06 ENSDART00000145251
pirin
chr23_+_25292147 0.06 ENSDART00000131486
proliferation-associated 2G4, b
chr4_+_34121902 0.06 ENSDART00000170225
si:ch211-223g7.6
chr21_-_24865217 0.05 ENSDART00000101136
immunoglobulin superfamily, member 9Bb
chr24_+_24086249 0.05 ENSDART00000002953
lipase, member Ib
chr23_+_27789795 0.05 ENSDART00000141458
lysine (K)-specific methyltransferase 2D
chr20_+_39223235 0.05 ENSDART00000132132
RALBP1 associated Eps domain containing 1
chr17_-_23673864 0.05 ENSDART00000104738
ENSDART00000128958
phosphatase and tensin homolog A
chr21_-_11286483 0.05 ENSDART00000074845
rhotekin 2b
chr3_-_55525627 0.05 ENSDART00000189234
testis expressed 2
chr14_+_28464736 0.05 ENSDART00000019003
proteasome 26S subunit, non-ATPase 10
chr17_-_23674065 0.05 ENSDART00000104735
ENSDART00000182952
phosphatase and tensin homolog A
chr3_+_17951790 0.05 ENSDART00000164663
ATP citrate lyase a
chr13_+_7241170 0.05 ENSDART00000109434
apoptosis-inducing factor, mitochondrion-associated, 2
chr14_+_30279391 0.05 ENSDART00000172794
fibrinogen-like 1
chr15_+_25438714 0.04 ENSDART00000154164
apoptosis-inducing factor, mitochondrion-associated, 4
chr15_+_25439106 0.04 ENSDART00000156252
apoptosis-inducing factor, mitochondrion-associated, 4
chr9_+_41474623 0.04 ENSDART00000137187
nuclear envelope integral membrane protein 2
chr24_+_24086491 0.04 ENSDART00000145092
lipase, member Ib
chr14_-_17588345 0.04 ENSDART00000143486
selenoprotein T, 2
chr8_+_18010978 0.04 ENSDART00000039887
ENSDART00000144532
single stranded DNA binding protein 3b
chr3_-_34816893 0.04 ENSDART00000084448
ENSDART00000154696
proteasome 26S subunit, non-ATPase 11a
chr9_-_34509997 0.04 ENSDART00000169114
protein phosphatase 2, regulatory subunit B'', beta
chr18_+_2222447 0.04 ENSDART00000185927
PIGB opposite strand 1
chr10_+_7718156 0.04 ENSDART00000189101
gamma-glutamyl carboxylase
chr8_+_18010568 0.04 ENSDART00000121984
single stranded DNA binding protein 3b
chr9_+_22466218 0.03 ENSDART00000131214
diacylglycerol kinase, gamma
chr7_+_56253914 0.03 ENSDART00000073594
ankyrin repeat domain 11
chr11_+_43401201 0.03 ENSDART00000190128
vasoactive intestinal peptide b
chr13_+_2357637 0.03 ENSDART00000017148
glutamate-cysteine ligase, catalytic subunit
chr4_+_5317483 0.03 ENSDART00000150366
si:ch211-214j24.10
chr9_-_23253870 0.03 ENSDART00000143657
ENSDART00000169911
aminocarboxymuconate semialdehyde decarboxylase
chr6_+_21395051 0.03 ENSDART00000017774
calcium channel, voltage-dependent, gamma subunit 5a
chr5_+_19314574 0.03 ENSDART00000133247
RUN and SH3 domain containing 2
chr4_+_42878556 0.03 ENSDART00000171047
si:zfos-451d2.2
chr4_-_60780423 0.03 ENSDART00000162632
si:dkey-254e13.6
chr4_-_71708567 0.03 ENSDART00000182645
si:dkeyp-4f2.1
chr24_-_27409599 0.03 ENSDART00000041770
chemokine (C-C motif) ligand 34b, duplicate 3
chr4_-_39448829 0.03 ENSDART00000168526
si:dkey-261o4.9
chr24_-_39354829 0.03 ENSDART00000169108
potassium inwardly-rectifying channel, subfamily J, member 12a
chr20_-_16972351 0.03 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
chr14_+_31496543 0.03 ENSDART00000170683
PHD finger protein 6
chr4_+_35189063 0.03 ENSDART00000185091
si:dkey-269p2.1
chr4_+_54645654 0.03 ENSDART00000192864
si:ch211-227e10.1
chr1_+_48256950 0.02 ENSDART00000171182
sortilin related VPS10 domain containing receptor 3
chr4_-_36032930 0.02 ENSDART00000191414
zgc:174180
chr7_+_17096903 0.02 ENSDART00000145357
ENSDART00000132706
HIV-1 Tat interactive protein 2
chr5_-_36592307 0.02 ENSDART00000126927
ENSDART00000051196
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_-_67471375 0.02 ENSDART00000147009
si:dkey-251i10.2
chr4_-_71913556 0.02 ENSDART00000167608
si:dkey-92c21.1
chr8_-_22660678 0.02 ENSDART00000181258
IQ motif and Sec7 domain 2a
chr4_-_36033377 0.02 ENSDART00000164348
ENSDART00000187058
zgc:174180
chr4_-_50930346 0.02 ENSDART00000184245
si:ch211-208f21.3
chr4_-_70308067 0.02 ENSDART00000165967
ENSDART00000134334
si:dkey-3h2.3
si:ch211-11p18.6
chr4_-_36476889 0.02 ENSDART00000163956
si:ch211-263l8.1
chr2_+_8261109 0.02 ENSDART00000024677
deleted in autism 1a
chr13_-_41546779 0.02 ENSDART00000163331
protocadherin-related 15a
chr15_-_16679517 0.02 ENSDART00000177384
calneuron 1
chr24_-_9689915 0.02 ENSDART00000185972
ENSDART00000093046
ubiquitin-like modifier activating enzyme 5
chr4_-_71708855 0.02 ENSDART00000158819
si:dkeyp-4f2.1
chr21_-_2415808 0.02 ENSDART00000171179
si:ch211-241b2.5
chr2_+_25278107 0.02 ENSDART00000131977
protein phosphatase 2, regulatory subunit B'', alpha
chr14_-_33312407 0.02 ENSDART00000135700
septin 6
chr8_-_21056012 0.02 ENSDART00000142852
zgc:112962
chr8_+_4434422 0.02 ENSDART00000145184
SRR1 domain containing
chr6_-_32349153 0.02 ENSDART00000140004
angiopoietin-like 3
chr2_+_24638367 0.02 ENSDART00000088346
microtubule associated serine/threonine kinase 3a
chr23_-_29376859 0.02 ENSDART00000146411
somatostatin 6
chr23_-_36823932 0.02 ENSDART00000142305
homeodomain interacting protein kinase 1a
chr5_-_31035198 0.02 ENSDART00000086534
cytochrome b5 domain containing 2
chr13_-_11644806 0.02 ENSDART00000169953
dynactin 1b
chr17_-_12966907 0.02 ENSDART00000022874
proteasome subunit alpha 6a
chr7_+_1442059 0.02 ENSDART00000173391
si:cabz01090193.1
chr3_+_58092212 0.02 ENSDART00000156059
si:ch211-256e16.7
chr2_-_8111346 0.02 ENSDART00000123103
plastin 1 (I isoform)
chr16_-_30833519 0.02 ENSDART00000191321
protein tyrosine kinase 2ab
chr13_-_38039871 0.02 ENSDART00000140645

chr10_-_74408 0.02 ENSDART00000100073
ENSDART00000141723
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
chr7_-_47282853 0.02 ENSDART00000169299
si:ch211-186j3.3
chr8_+_39511932 0.02 ENSDART00000113511
leucine zipper, putative tumor suppressor 1
chr8_-_36399884 0.02 ENSDART00000108538
si:zfos-2070c2.3
chr5_-_16405651 0.02 ENSDART00000163942
solute carrier family 39 (zinc transporter), member 14
chr23_-_12906228 0.02 ENSDART00000138807
necdin-like 2
chr21_-_3826706 0.02 ENSDART00000053607
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr24_-_24281792 0.02 ENSDART00000146482
ENSDART00000018420
pyruvate dehydrogenase E1 alpha 1 subunit b
chr19_-_32937582 0.02 ENSDART00000144721
antizyme inhibitor 1b
chr21_+_45316330 0.02 ENSDART00000056474
ENSDART00000149314
ENSDART00000149272
ENSDART00000149156
ENSDART00000099497
transcription factor 7
chr3_+_32391540 0.02 ENSDART00000156608
adaptor-related protein complex 2, alpha 1 subunit
chr22_+_9027884 0.02 ENSDART00000171839
si:ch211-213a13.2
chr20_-_15090862 0.02 ENSDART00000063892
ENSDART00000122592
si:dkey-239i20.2
chr15_-_8191841 0.02 ENSDART00000156663
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr17_-_22001935 0.02 ENSDART00000185429
ENSDART00000193302
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 2
chr1_+_51039558 0.02 ENSDART00000024743
dpy-30 histone methyltransferase complex regulatory subunit
chr17_-_11439815 0.01 ENSDART00000130105
proteasome subunit alpha 3
chr3_+_41731527 0.01 ENSDART00000049007
ENSDART00000187866
carbohydrate (chondroitin 4) sulfotransferase 12a
chr2_-_26642831 0.01 ENSDART00000132854
ENSDART00000087714
ENSDART00000132651
U2 snRNP-associated SURP domain containing
chr19_+_24872159 0.01 ENSDART00000158490
si:ch211-195b13.1
chr15_-_26552652 0.01 ENSDART00000152336
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr13_+_1430094 0.01 ENSDART00000169888
si:ch211-165e15.1
chr17_-_22001303 0.01 ENSDART00000122190
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 2
chr9_-_14992730 0.01 ENSDART00000137117
par-3 family cell polarity regulator beta b
chr24_+_17140938 0.01 ENSDART00000149134
MLLT10, histone lysine methyltransferase DOT1L cofactor
chr21_-_45349548 0.01 ENSDART00000008454
S-phase kinase-associated protein 1
chr18_+_17537344 0.01 ENSDART00000025782
nucleoporin 93
chr9_+_11202552 0.01 ENSDART00000151931
acid-sensing (proton-gated) ion channel family member 4a
chr1_-_10577945 0.01 ENSDART00000179237
ENSDART00000040502
ENSDART00000186876
transient receptor potential cation channel, subfamily C, member 5a
chr22_-_16416882 0.01 ENSDART00000062749
cathepsin 12
chr4_+_76442674 0.01 ENSDART00000164825
si:dkey-16p6.1
chr4_+_40218600 0.01 ENSDART00000152091
zinc finger protein 995
chr10_-_7974155 0.01 ENSDART00000147368
ENSDART00000075524
oxysterol binding protein 2
chr21_+_27302752 0.01 ENSDART00000012855
SART1, U4/U6.U5 tri-snRNP-associated protein 1
chr22_+_1110855 0.01 ENSDART00000168251
si:ch1073-181h11.1
chr24_+_26039464 0.01 ENSDART00000131017
tyrosine kinase, non-receptor, 2a
chr3_+_23063718 0.01 ENSDART00000140225
ENSDART00000184431
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 1
chr23_-_37432459 0.01 ENSDART00000188916
zmp:0000001088
chr8_-_21058354 0.01 ENSDART00000130481
ENSDART00000113749
zgc:112962
chr20_-_35557902 0.01 ENSDART00000134753
adhesion G protein-coupled receptor F7
chr19_+_8506178 0.01 ENSDART00000189689
S100 calcium binding protein A10a
chr16_-_27640995 0.01 ENSDART00000019658
NAC alpha domain containing
chr8_+_22859718 0.01 ENSDART00000134151
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr18_+_33009828 0.01 ENSDART00000160100
olfactory receptor C family, j1
chr11_+_43401592 0.01 ENSDART00000112468
vasoactive intestinal peptide b
chr23_-_14769523 0.01 ENSDART00000054909
glutathione synthetase
chr7_-_2116512 0.01 ENSDART00000098148
si:cabz01007802.1
chr4_+_54225677 0.01 ENSDART00000166637
zinc finger protein 995
chr7_+_17992455 0.01 ENSDART00000089211
ENSDART00000190881
EH domain binding protein 1-like 1a
chr4_-_55040507 0.01 ENSDART00000161731
si:dkey-56m15.3
chr11_+_2198831 0.01 ENSDART00000160515
homeobox C6b
chr20_-_26866111 0.01 ENSDART00000077767
myosin light chain kinase family, member 4b
chr4_-_8902406 0.01 ENSDART00000192962
metallophosphoesterase domain containing 1
chr19_-_19379084 0.01 ENSDART00000165206
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr2_-_31800521 0.01 ENSDART00000112763
reticulophagy regulator 1
chr12_-_16990896 0.01 ENSDART00000152402
interferon-induced protein with tetratricopeptide repeats 12
chr19_-_10478229 0.01 ENSDART00000142937
si:ch211-171h4.5
chr13_-_40302710 0.00 ENSDART00000144360
pyridine nucleotide-disulphide oxidoreductase domain 2
chr25_+_29474982 0.00 ENSDART00000130410
interleukin 17 receptor E-like
chr7_-_19043401 0.00 ENSDART00000158796
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr4_-_20292821 0.00 ENSDART00000136069
ENSDART00000192504
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr24_-_23998897 0.00 ENSDART00000130053
zmp:0000000991
chr10_-_19523752 0.00 ENSDART00000160057
si:ch211-127i16.2
chr23_-_15878879 0.00 ENSDART00000010119
eukaryotic translation elongation factor 1 alpha 2
chr8_+_20825987 0.00 ENSDART00000133309
si:ch211-133l5.4
chr22_-_14696667 0.00 ENSDART00000180379
low density lipoprotein receptor-related protein 1Ba
chr14_+_923522 0.00 ENSDART00000185878
myozenin 3a
chr25_+_29474583 0.00 ENSDART00000191189
interleukin 17 receptor E-like

Network of associatons between targets according to the STRING database.

First level regulatory network of nfe2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0071451 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.0 GO:0070459 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.0 GO:0006750 glutathione biosynthetic process(GO:0006750)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.0 0.1 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.0 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation