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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nfatc2a

Z-value: 1.24

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Transcription factors associated with nfatc2a

Gene Symbol Gene ID Gene Info
ENSDARG00000100927 nuclear factor of activated T cells 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfatc2adr11_v1_chr23_+_39089574_39089574-0.551.7e-02Click!

Activity profile of nfatc2a motif

Sorted Z-values of nfatc2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_46040666 1.41 ENSDART00000060744
si:dkey-7c18.24
chr19_+_41479990 1.27 ENSDART00000087187
argonaute RISC catalytic component 2
chr24_-_17029374 1.20 ENSDART00000039267
prostaglandin D2 synthase b, tandem duplicate 1
chr12_-_25887864 1.15 ENSDART00000152983
si:dkey-193p11.2
chr5_-_3991655 1.11 ENSDART00000159368
myosin XIX
chr17_-_30521043 1.11 ENSDART00000087111
intersectin 2b
chr8_+_13106760 1.08 ENSDART00000029308
integrin, beta 4
chr10_+_5954787 1.06 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr7_+_33424044 1.04 ENSDART00000180260
glucuronic acid epimerase b
chr18_-_39696853 1.01 ENSDART00000148383
Dmx-like 2
chr1_+_44173506 0.99 ENSDART00000170512
catenin (cadherin-associated protein), delta 1
chr23_-_33558161 0.98 ENSDART00000018301
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_+_14454663 0.97 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr4_-_1720648 0.97 ENSDART00000103484
growth arrest-specific 2 like 3
chr8_-_22558773 0.90 ENSDART00000074309
porcupine O-acyltransferase like
chr2_+_24638367 0.89 ENSDART00000088346
microtubule associated serine/threonine kinase 3a
chr6_+_36821621 0.89 ENSDART00000104157
transmembrane protein 45a
chr1_+_36771954 0.88 ENSDART00000149022
Rho GTPase activating protein 10
chr3_-_15470944 0.88 ENSDART00000185302
spinster homolog 1 (Drosophila)
chr5_-_69041102 0.87 ENSDART00000161561
ankyrin 1, erythrocytic a
chr11_+_24046179 0.87 ENSDART00000006703
MAF1 homolog, negative regulator of RNA polymerase III
chr14_+_26759332 0.87 ENSDART00000088484
AHNAK nucleoprotein
chr16_+_12812472 0.87 ENSDART00000008535
U2 small nuclear RNA auxiliary factor 2a
chr11_-_21404358 0.86 ENSDART00000129062
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr6_-_39313027 0.86 ENSDART00000012644
keratin 4
chr23_+_27782071 0.85 ENSDART00000131379
lysine (K)-specific methyltransferase 2D
chr22_-_26353916 0.84 ENSDART00000077958
calpain 2, (m/II) large subunit b
chr14_+_6615564 0.83 ENSDART00000139292
si:dkeyp-44a8.2
chr19_-_4137087 0.80 ENSDART00000164611
Ras-related GTP binding Cb
chr16_-_13281380 0.78 ENSDART00000103882
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr6_-_49547680 0.78 ENSDART00000169678
protein phosphatase 4, regulatory subunit 1-like
chr1_+_52632856 0.77 ENSDART00000011725
solute carrier family 44 (choline transporter), member 1a
chr17_+_20569806 0.76 ENSDART00000113936
zgc:162183
chr1_+_26677406 0.75 ENSDART00000183427
ENSDART00000180366
ENSDART00000181997
si:dkey-25o16.4
chr9_-_23807032 0.75 ENSDART00000027443
extended synaptotagmin-like protein 3
chr11_-_11882982 0.75 ENSDART00000190853
WAS/WASL interacting protein family, member 2a
chr11_-_33618612 0.73 ENSDART00000033980
LIM and senescent cell antigen-like domains 1
chr19_+_6938289 0.73 ENSDART00000139122
ENSDART00000178832
flotillin 1b
chr9_-_11263228 0.73 ENSDART00000113847
chondroitin polymerizing factor a
chr23_+_1181248 0.73 ENSDART00000170942
utrophin
chr12_-_3133483 0.72 ENSDART00000015092
collagen, type I, alpha 1b
chr13_-_24825691 0.71 ENSDART00000142745
STE20-like kinase a
chr9_-_9209831 0.71 ENSDART00000026275
cystathionine-beta-synthase b
chr21_+_15756549 0.70 ENSDART00000026903
protein tyrosine phosphatase, receptor type, A
chr16_-_6205790 0.70 ENSDART00000038495
catenin (cadherin-associated protein), beta 1
chr4_-_3353595 0.70 ENSDART00000009076
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr1_+_26676758 0.69 ENSDART00000152299
si:dkey-25o16.4
chr8_+_47683539 0.69 ENSDART00000190701
dipeptidyl-peptidase 9
chr16_-_38333976 0.69 ENSDART00000031895
CDC42 small effector 1
chr14_+_31509922 0.69 ENSDART00000124499
hypoxanthine phosphoribosyltransferase 1
chr19_-_6193448 0.69 ENSDART00000151405
Ets2 repressor factor
chr2_+_15069011 0.68 ENSDART00000145893
calponin 3, acidic b
chr10_+_44986419 0.68 ENSDART00000162566
H2A histone family, member Vb
chr13_-_40282770 0.68 ENSDART00000140875
zgc:123010
chr19_-_24267410 0.68 ENSDART00000104083
S100 calcium binding protein V2
chr8_+_47683352 0.68 ENSDART00000187320
ENSDART00000192605
dipeptidyl-peptidase 9
chr1_-_43920371 0.68 ENSDART00000109283
secretory calcium-binding phosphoprotein 7
chr5_-_19963537 0.68 ENSDART00000148146
si:dkey-234h16.7
chr10_-_41352502 0.67 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr2_+_35993404 0.67 ENSDART00000170845
laminin, gamma 2
chr18_+_50669456 0.67 ENSDART00000163005
si:dkey-151j17.4
chr12_-_3840664 0.67 ENSDART00000160967
TAO kinase 2b
chr5_+_31168096 0.66 ENSDART00000086443
ENSDART00000192271
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr20_-_18789543 0.66 ENSDART00000182240
cerebral cavernous malformation 2
chr16_-_17345377 0.66 ENSDART00000143056
zyxin
chr3_-_20063671 0.66 ENSDART00000056614
ENSDART00000126915
upstream binding transcription factor, RNA polymerase I
chr17_-_11418513 0.66 ENSDART00000064412
ENSDART00000151847
AT rich interactive domain 4A (RBP1-like)
chr20_+_14977260 0.66 ENSDART00000186424
vesicle-associated membrane protein 4
chr17_-_8592824 0.65 ENSDART00000127022

chr7_+_51795667 0.65 ENSDART00000174201
ENSDART00000073839
solute carrier family 38, member 7
chr9_-_16133263 0.65 ENSDART00000077187
myosin IB
chr5_-_68074592 0.65 ENSDART00000165052
ENSDART00000018792
sperm associated antigen 7
chr24_-_34335265 0.64 ENSDART00000128690
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr21_+_6291027 0.64 ENSDART00000180467
ENSDART00000184952
ENSDART00000184006
formin binding protein 1b
chr4_-_7876005 0.64 ENSDART00000109252
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr15_-_8856785 0.64 ENSDART00000192816
RAB4B, member RAS oncogene family
chr23_+_9522942 0.64 ENSDART00000137751
oxysterol binding protein-like 2b
chr19_+_46222918 0.63 ENSDART00000158703
vacuolar protein sorting 28 (yeast)
chr24_-_32025637 0.63 ENSDART00000180448
ENSDART00000159034
Ras suppressor protein 1
chr22_+_15720381 0.63 ENSDART00000128149
family with sequence similarity 32, member A
chr3_-_37699992 0.62 ENSDART00000151193
G patch domain containing 8
chr10_+_44955106 0.62 ENSDART00000185837
interleukin 1, beta
chr16_-_21903083 0.62 ENSDART00000165849
SET domain, bifurcated 1b
chr12_+_17603528 0.62 ENSDART00000111565
PMS1 homolog 2, mismatch repair system component
chr9_+_24936496 0.62 ENSDART00000157474
solute carrier family 39 (zinc transporter), member 10
chr3_-_40054615 0.62 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
lethal giant larvae homolog 1 (Drosophila)
chr19_-_20403507 0.62 ENSDART00000052603
ENSDART00000137590
deleted in azoospermia-like
chr5_-_48664522 0.62 ENSDART00000083229
metallo-beta-lactamase domain containing 2
chr14_-_46616487 0.62 ENSDART00000105417
ENSDART00000166550
ENSDART00000105418
prominin 1a
chr12_+_33403694 0.62 ENSDART00000124083
fatty acid synthase
chr13_+_13681681 0.61 ENSDART00000057825
complement factor D (adipsin)
chr17_-_45370200 0.61 ENSDART00000186208
zinc finger protein 106a
chr25_-_25566363 0.61 ENSDART00000185770
hypermethylated in cancer 1 like
chr19_-_11336782 0.61 ENSDART00000131014
septin 7a
chr9_-_12659140 0.61 ENSDART00000058565
PTTG1 interacting protein b
chr19_+_43684376 0.60 ENSDART00000051723
si:ch211-193k19.1
chr22_+_17433968 0.60 ENSDART00000139523
RAB GTPase activating protein 1-like
chr9_+_16241656 0.60 ENSDART00000154326
si:ch211-261p9.4
chr16_-_42461263 0.59 ENSDART00000109259
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
chr17_+_21887823 0.59 ENSDART00000131929
ENSDART00000165192
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a
chr16_-_7793457 0.59 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr2_-_37353098 0.59 ENSDART00000056522
SKI-like proto-oncogene a
chr14_-_31856819 0.59 ENSDART00000003345
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr7_+_13609457 0.59 ENSDART00000172857
ankyrin repeat and death domain containing 1A
chr9_-_19092322 0.59 ENSDART00000131957
cytokine receptor family member b2
chr3_-_40976288 0.59 ENSDART00000193553
cytochrome P450, family 3, subfamily c, polypeptide 1
chr3_-_23575007 0.58 ENSDART00000155282
ENSDART00000087726
insulin-like growth factor 2 mRNA binding protein 1
chr15_+_21262917 0.58 ENSDART00000101000
glucuronokinase with putative uridyl pyrophosphorylase
chr6_+_10333920 0.58 ENSDART00000151667
ENSDART00000151477
cordon-bleu WH2 repeat protein-like 1a
chr19_-_46058963 0.58 ENSDART00000170409
nucleoporin 153
chr17_-_15528597 0.58 ENSDART00000150232
FYN proto-oncogene, Src family tyrosine kinase a
chr21_-_2814709 0.57 ENSDART00000097664
semaphorin 4D
chr20_-_2355357 0.57 ENSDART00000085281
si:ch73-18b11.1
chr3_+_40409100 0.57 ENSDART00000103486
trinucleotide repeat containing 18
chr11_+_10909183 0.57 ENSDART00000064860
RNA binding motif, single stranded interacting protein 1a
chr25_-_3745393 0.57 ENSDART00000037973
MORC family CW-type zinc finger 2
chr12_+_22560067 0.57 ENSDART00000172066
polymerase (RNA) II (DNA directed) polypeptide A
chr5_-_40190949 0.57 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr5_+_13521081 0.56 ENSDART00000171975
si:ch211-230g14.6
chr17_+_25519089 0.56 ENSDART00000041721
crystallin beta-gamma domain containing 1a
chr3_-_5067585 0.56 ENSDART00000169609
thyrotrophic embryonic factor b
chr19_-_20403845 0.56 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
deleted in azoospermia-like
chr10_-_6867282 0.56 ENSDART00000144001
ENSDART00000109744
diphosphoinositol pentakisphosphate kinase 2
chr19_+_37120491 0.56 ENSDART00000032341
penta-EF-hand domain containing 1
chr12_-_3453589 0.56 ENSDART00000175918

chr21_+_37090585 0.56 ENSDART00000182971
zinc finger protein 346
chr9_+_33158191 0.56 ENSDART00000180786
dopey family member 2
chr16_+_23397785 0.56 ENSDART00000148961
S100 calcium binding protein A10b
chr23_+_27779452 0.55 ENSDART00000134785
lysine (K)-specific methyltransferase 2D
chr6_+_27667359 0.55 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr15_-_29354020 0.55 ENSDART00000127795
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr21_+_37090795 0.55 ENSDART00000085786
zinc finger protein 346
chr8_+_53423408 0.54 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr2_+_36015049 0.54 ENSDART00000158276
laminin, gamma 2
chr25_-_36263115 0.54 ENSDART00000143046
ENSDART00000139002
dihydrouridine synthase 2
chr23_+_19790962 0.54 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr14_+_45028062 0.54 ENSDART00000184717
ENSDART00000185481
ATPase phospholipid transporting 8A1
chr16_+_12812214 0.54 ENSDART00000124875
U2 small nuclear RNA auxiliary factor 2a
chr22_-_21046843 0.53 ENSDART00000133982
single stranded DNA binding protein 4
chr16_-_48428035 0.53 ENSDART00000190554
RAD21 cohesin complex component a
chr19_+_9050852 0.53 ENSDART00000151031
ash1 (absent, small, or homeotic)-like (Drosophila)
chr20_-_2298970 0.53 ENSDART00000136067
si:ch73-18b11.1
chr23_+_1276006 0.53 ENSDART00000162294
utrophin
chr3_-_46410387 0.53 ENSDART00000156822
cell death-inducing p53 target 1
chr2_-_3077027 0.53 ENSDART00000109319
ADP-ribosylation factor 1
chr6_+_37754763 0.53 ENSDART00000110770
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr25_-_3623847 0.53 ENSDART00000172586
si:ch211-272n13.3
chr6_-_19333947 0.53 ENSDART00000160887
ggolgi-associated, gamma adaptin ear containing, ARF binding protein 3
chr23_-_24682244 0.52 ENSDART00000104035
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr21_-_3700334 0.52 ENSDART00000137844
ATPase phospholipid transporting 8B1
chr19_-_6193067 0.52 ENSDART00000092656
ENSDART00000140347
Ets2 repressor factor
chr3_+_53156813 0.52 ENSDART00000114343
bromodomain containing 4
chr23_-_18415872 0.52 ENSDART00000135430
family with sequence similarity 120C
chr15_+_19991280 0.52 ENSDART00000186677
zgc:112083
chr6_-_49537646 0.52 ENSDART00000180438

chr18_+_27489595 0.52 ENSDART00000182018
tumor protein p53 inducible protein 11b
chr10_+_36029537 0.51 ENSDART00000165386
high mobility group box 1a
chr21_+_18405585 0.51 ENSDART00000139318
si:dkey-1d7.3
chr13_+_33024547 0.51 ENSDART00000057377
arginase 2
chr8_+_28452738 0.51 ENSDART00000062706
transmembrane protein 189
chr13_+_25364753 0.51 ENSDART00000027428
conserved helix-loop-helix ubiquitous kinase
chr19_-_27827744 0.51 ENSDART00000181620
PAP associated domain containing 7
chr13_-_42749916 0.50 ENSDART00000140019
calpain 2, (m/II) large subunit a
chr14_-_22495604 0.50 ENSDART00000137167
si:ch211-107m4.1
chr8_-_38022298 0.50 ENSDART00000067809
RAB11 family interacting protein 1 (class I) a
chr11_+_5588122 0.50 ENSDART00000113281
zgc:172302
chr20_-_45807982 0.50 ENSDART00000074546
fermitin family member 1
chr10_-_1718395 0.50 ENSDART00000137620
si:ch73-46j18.5
chr12_-_23320266 0.50 ENSDART00000181711
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr3_+_30921246 0.50 ENSDART00000076850
claudin i
chr22_-_20950448 0.50 ENSDART00000002029
FK506 binding protein 8
chr8_-_33154677 0.50 ENSDART00000133300
zinc finger and BTB domain containing 34
chr1_+_44173245 0.49 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
catenin (cadherin-associated protein), delta 1
chr17_+_25444323 0.49 ENSDART00000030691
chloride intracellular channel 4
chr12_+_16953415 0.49 ENSDART00000020824
pantothenate kinase 1b
chr20_+_6535176 0.49 ENSDART00000054652
si:ch211-191a24.4
chr5_+_22133153 0.49 ENSDART00000016214
moesin a
chr8_-_9570511 0.49 ENSDART00000044000
plexin A3
chr25_+_26901149 0.49 ENSDART00000153839
zinc finger protein 800a
chr8_+_49975160 0.49 ENSDART00000156403
ENSDART00000080135
glutamine--fructose-6-phosphate transaminase 1
chr6_-_7735153 0.49 ENSDART00000151545
solute carrier family 25, member 38b
chr21_-_43482426 0.49 ENSDART00000192901
ankyrin repeat domain 46a
chr20_-_3319642 0.49 ENSDART00000186743
ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr9_-_9842149 0.48 ENSDART00000121456
follistatin-like 1b
chr2_-_38206034 0.48 ENSDART00000144518
ENSDART00000137395
apoptotic chromatin condensation inducer 1a
chr21_+_31253048 0.48 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
argininosuccinate lyase
chr23_-_18668836 0.48 ENSDART00000138792
ENSDART00000051182
Rho GTPase activating protein 4b
chr25_-_12902242 0.47 ENSDART00000164733
septin 15
chr13_+_25505580 0.47 ENSDART00000140634
inositol polyphosphate-5-phosphatase F
chr19_-_13774502 0.47 ENSDART00000159711
erythrocyte membrane protein band 4.1a
chr20_+_27087539 0.47 ENSDART00000062094
transmembrane protein 251
chr22_+_17536989 0.47 ENSDART00000149531
heterogeneous nuclear ribonucleoprotein M
chr2_-_37462462 0.47 ENSDART00000145896
si:dkey-57k2.7
chr10_-_3258073 0.47 ENSDART00000113162
phosphatidylinositol 4-kinase, catalytic, alpha a
chr13_+_39297802 0.47 ENSDART00000133636
si:dkey-85a20.4
chr9_+_37366973 0.47 ENSDART00000016370
disrupted in renal carcinoma 2
chr22_-_21046654 0.47 ENSDART00000064902
single stranded DNA binding protein 4
chr20_-_14462995 0.47 ENSDART00000152418
ENSDART00000044125
gene rich cluster, C10 gene
chr9_+_23003208 0.47 ENSDART00000021060
ELL associated factor 2
chr19_-_10214264 0.47 ENSDART00000053300
ENSDART00000148225
zinc finger protein 865

Network of associatons between targets according to the STRING database.

First level regulatory network of nfatc2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.3 1.2 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.3 0.9 GO:0061355 Wnt protein secretion(GO:0061355)
0.3 1.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 0.8 GO:0010586 miRNA metabolic process(GO:0010586)
0.3 1.3 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 0.7 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.2 0.7 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.2 0.7 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.2 0.7 GO:0006178 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.2 0.6 GO:0060031 mediolateral intercalation(GO:0060031)
0.2 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.5 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.2 0.5 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 1.0 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.2 0.7 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 1.0 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 0.5 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.2 0.6 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 1.4 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 0.6 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.9 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 0.6 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.1 0.4 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.5 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.4 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.5 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.4 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.6 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.5 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.3 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.1 0.9 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1 0.4 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.9 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.1 0.6 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.4 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 1.0 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.2 GO:0070814 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.3 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.1 0.5 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.3 GO:0071962 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.5 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.4 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.2 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.1 0.2 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.1 0.2 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.4 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.2 GO:0032816 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.4 GO:0046660 female sex differentiation(GO:0046660)
0.1 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.7 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.2 GO:0032241 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.2 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.1 0.6 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.3 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.4 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.2 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.1 0.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.8 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 0.6 GO:0033700 phospholipid efflux(GO:0033700)
0.1 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.4 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.9 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.1 0.3 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 0.2 GO:0034154 toll-like receptor 3 signaling pathway(GO:0034138) toll-like receptor 7 signaling pathway(GO:0034154)
0.1 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.7 GO:0090398 cellular senescence(GO:0090398)
0.1 0.4 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.2 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 0.1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.1 0.3 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.1 0.4 GO:0030643 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 1.0 GO:0048844 artery morphogenesis(GO:0048844)
0.1 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.2 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.0 0.3 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.6 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.3 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.0 1.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0033337 dorsal fin development(GO:0033337)
0.0 0.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 1.5 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.4 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.6 GO:0006984 ER-nucleus signaling pathway(GO:0006984)
0.0 0.1 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.6 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0046639 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) negative regulation of T cell differentiation(GO:0045581) regulation of T-helper cell differentiation(GO:0045622) negative regulation of T-helper cell differentiation(GO:0045623) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) negative regulation of alpha-beta T cell differentiation(GO:0046639) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.5 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0051026 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.4 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.6 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.3 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.2 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.1 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.5 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.3 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0050936 xanthophore differentiation(GO:0050936)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.3 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0010165 response to X-ray(GO:0010165)
0.0 1.3 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.4 GO:0007548 sex differentiation(GO:0007548)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.9 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0051785 positive regulation of mitotic nuclear division(GO:0045840) positive regulation of nuclear division(GO:0051785)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.3 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.1 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0045176 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.3 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.9 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.7 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.6 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0045110 intermediate filament organization(GO:0045109) intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0009791 post-embryonic development(GO:0009791)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 1.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.0 GO:0048883 neuromast primordium migration(GO:0048883)
0.0 0.5 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.2 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.4 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.1 GO:0070285 pigment cell development(GO:0070285)
0.0 0.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 2.7 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.1 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.1 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.6 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:1901317 regulation of sperm motility(GO:1901317)
0.0 0.1 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 1.0 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.7 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0032418 lysosome localization(GO:0032418)
0.0 0.2 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 1.1 GO:0051236 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.0 0.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.6 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.5 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 1.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.0 GO:0007309 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte animal/vegetal axis specification(GO:0060832)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0005845 mRNA cap binding complex(GO:0005845)
0.3 1.0 GO:0043291 RAVE complex(GO:0043291)
0.2 1.0 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.7 GO:0016600 flotillin complex(GO:0016600)
0.2 0.9 GO:0043034 costamere(GO:0043034)
0.2 1.4 GO:0089701 U2AF(GO:0089701)
0.1 1.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.5 GO:0014704 intercalated disc(GO:0014704)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 0.7 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 1.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 1.0 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.2 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:0016586 RSC complex(GO:0016586)
0.1 0.3 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.6 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.5 GO:0071914 prominosome(GO:0071914)
0.1 1.1 GO:0005903 brush border(GO:0005903)
0.1 0.9 GO:0071564 npBAF complex(GO:0071564)
0.1 2.2 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.8 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 1.3 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 1.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0030428 cell septum(GO:0030428)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 3.3 GO:0005912 adherens junction(GO:0005912)
0.0 0.3 GO:0070461 SAGA-type complex(GO:0070461)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 1.8 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.2 GO:0005923 bicellular tight junction(GO:0005923) apical junction complex(GO:0043296) occluding junction(GO:0070160)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0035197 siRNA binding(GO:0035197)
0.3 1.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 0.9 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.3 1.0 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.2 0.7 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.2 1.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 0.7 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.6 GO:0004904 interferon receptor activity(GO:0004904)
0.2 0.5 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.9 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.2 1.3 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 0.9 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.6 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 1.2 GO:0008494 translation activator activity(GO:0008494)
0.1 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 1.0 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.7 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.3 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.6 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.5 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.9 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.6 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.3 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.1 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.2 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.6 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.2 GO:0070513 death domain binding(GO:0070513)
0.1 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.0 0.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.9 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 2.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 2.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.3 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.0 2.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.0 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 9.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.6 GO:0060090 binding, bridging(GO:0060090)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 2.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.5 PID IGF1 PATHWAY IGF1 pathway
0.1 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 2.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 3.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME AXON GUIDANCE Genes involved in Axon guidance
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK