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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for myog
Z-value: 1.06
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Transcription factors associated with myog
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| myog | dr11_v1_chr11_-_22605981_22605981 | -0.92 | 6.9e-08 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_14109348 Show fit | 3.59 |
ENSDART00000159015
|
zgc:175136 |
|
| chr7_-_20582842 Show fit | 2.80 |
ENSDART00000169750
ENSDART00000111719 |
si:dkey-19b23.11 |
|
| chr2_-_11027258 Show fit | 2.79 |
ENSDART00000081072
ENSDART00000193824 ENSDART00000187036 ENSDART00000097741 |
single stranded DNA binding protein 3a |
|
| chr15_+_25489406 Show fit | 2.72 |
ENSDART00000162482
|
zgc:152863 |
|
| chr20_+_34502606 Show fit | 2.29 |
ENSDART00000139739
|
golgin, rab6-interacting |
|
| chr21_-_19919020 Show fit | 2.26 |
ENSDART00000147396
|
protein phosphatase 1, regulatory subunit 3B |
|
| chr6_+_153146 Show fit | 2.13 |
ENSDART00000097468
|
zinc finger, GATA-like protein 1 |
|
| chr2_+_6253246 Show fit | 2.12 |
ENSDART00000058256
ENSDART00000076700 |
zona pellucida glycoprotein 3b |
|
| chr2_-_17115256 Show fit | 2.12 |
ENSDART00000190488
|
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) |
|
| chr2_-_17114852 Show fit | 1.90 |
ENSDART00000006549
|
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) |
Network of associatons between targets according to the STRING database.
First level regulatory network of myog
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.0 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
| 0.3 | 3.7 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.1 | 3.5 | GO:0006998 | nuclear envelope organization(GO:0006998) |
| 0.1 | 2.8 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
| 0.0 | 2.6 | GO:0045930 | negative regulation of mitotic cell cycle(GO:0045930) |
| 0.8 | 2.3 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 2.3 | GO:0042752 | regulation of circadian rhythm(GO:0042752) |
| 0.0 | 2.2 | GO:0097191 | extrinsic apoptotic signaling pathway(GO:0097191) |
| 0.2 | 2.1 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
| 0.1 | 2.1 | GO:0035803 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.2 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 4.0 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 3.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 2.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 2.6 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.0 | 2.4 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 2.3 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.2 | 2.1 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 1.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.5 | GO:0009925 | basal plasma membrane(GO:0009925) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 4.0 | GO:0043139 | 5'-3' DNA helicase activity(GO:0043139) |
| 0.5 | 3.7 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.0 | 2.9 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 2.9 | GO:0042393 | histone binding(GO:0042393) |
| 0.2 | 2.6 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 2.6 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 2.6 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.2 | 2.3 | GO:2001069 | glycogen binding(GO:2001069) |
| 0.2 | 2.1 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 0.0 | 1.9 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 3.6 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 2.9 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 1.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.0 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 0.8 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.7 | PID IL3 PATHWAY | IL3-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.7 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.2 | 2.8 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.2 | 1.7 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 1.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.6 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 1.5 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 1.2 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 1.1 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 1.1 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.0 | 1.0 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |