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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for myog

Z-value: 1.06

Motif logo

Transcription factors associated with myog

Gene Symbol Gene ID Gene Info
ENSDARG00000009438 myogenin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
myogdr11_v1_chr11_-_22605981_22605981-0.926.9e-08Click!

Activity profile of myog motif

Sorted Z-values of myog motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_14109348 3.59 ENSDART00000159015
zgc:175136
chr7_-_20582842 2.80 ENSDART00000169750
ENSDART00000111719
si:dkey-19b23.11
chr2_-_11027258 2.79 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
single stranded DNA binding protein 3a
chr15_+_25489406 2.72 ENSDART00000162482
zgc:152863
chr20_+_34502606 2.29 ENSDART00000139739
golgin, rab6-interacting
chr21_-_19919020 2.26 ENSDART00000147396
protein phosphatase 1, regulatory subunit 3B
chr6_+_153146 2.13 ENSDART00000097468
zinc finger, GATA-like protein 1
chr2_+_6253246 2.12 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr2_-_17115256 2.12 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr2_-_17114852 1.90 ENSDART00000006549
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr7_-_48263516 1.87 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr17_+_1360192 1.87 ENSDART00000184561
SIVA1, apoptosis-inducing factor
chr16_+_39159752 1.77 ENSDART00000122081
syntabulin (syntaxin-interacting)
chr13_+_8840772 1.75 ENSDART00000059321
epithelial cell adhesion molecule
chr18_+_15271993 1.75 ENSDART00000099777
si:dkey-103i16.6
chr12_-_13729263 1.73 ENSDART00000078021
forkhead box H1
chr20_-_29498178 1.73 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
ribonucleotide reductase M2 polypeptide
chr5_+_26212621 1.70 ENSDART00000134432
occludin b
chr3_+_7771420 1.68 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr19_+_14454306 1.68 ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr23_+_553396 1.59 ENSDART00000034707
LSM family member 14B
chr21_-_38717854 1.59 ENSDART00000065169
ENSDART00000113813
seven in absentia homolog 2 (Drosophila)-like
chr10_-_44560165 1.52 ENSDART00000181217
ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr1_+_59321629 1.50 ENSDART00000161981
poly(A)-specific ribonuclease (deadenylation nuclease)
chr12_-_25380028 1.48 ENSDART00000142674
zinc finger protein 36, C3H type-like 2
chr8_-_18613948 1.46 ENSDART00000089172
coproporphyrinogen oxidase
chr9_+_21306902 1.45 ENSDART00000138554
ENSDART00000004108
exportin 4
chr6_+_21001264 1.45 ENSDART00000044519
ENSDART00000151278
connexin 44.2
chr23_-_22523303 1.45 ENSDART00000079019
splA/ryanodine receptor domain and SOCS box containing 1
chr13_+_2894536 1.43 ENSDART00000183678

chr23_+_384850 1.39 ENSDART00000114000
zgc:101663
chr12_-_10512911 1.35 ENSDART00000124562
ENSDART00000106163
zgc:152977
chr3_-_40836081 1.35 ENSDART00000143135
WD repeat domain, phosphoinositide interacting 2
chr23_-_18057270 1.33 ENSDART00000173385
zgc:92287
chr8_-_1838315 1.30 ENSDART00000114476
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr14_-_34605607 1.28 ENSDART00000191608
actin filament associated protein 1-like 1a
chr21_-_217589 1.26 ENSDART00000185017

chr13_-_32726178 1.25 ENSDART00000012232
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr7_+_34794829 1.25 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
epithelial splicing regulatory protein 2
chr22_-_10541372 1.24 ENSDART00000179708
si:dkey-42i9.4
chr19_-_30810328 1.23 ENSDART00000184875
MYCL proto-oncogene, bHLH transcription factor b
chr23_+_44614056 1.23 ENSDART00000188379
enolase 3, (beta, muscle)
chr17_-_51818659 1.22 ENSDART00000111389
ENSDART00000157244
exonuclease 3'-5' domain containing 2
chr14_-_25928899 1.22 ENSDART00000143518
GTPase activating protein (SH3 domain) binding protein 1
chr12_-_10508952 1.22 ENSDART00000152806
zgc:152977
chr8_-_1255321 1.19 ENSDART00000149605
cell division cycle 14B
chr9_-_39624173 1.18 ENSDART00000180106
ENSDART00000126766
erb-b2 receptor tyrosine kinase 4b
chr12_+_5251647 1.17 ENSDART00000124097
phospholipase C, epsilon 1
chr19_-_47571456 1.17 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr1_+_27690 1.16 ENSDART00000162928
embryonic ectoderm development
chr5_-_32336613 1.14 ENSDART00000139732
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_-_49854432 1.14 ENSDART00000180731
biliverdin reductase A
chr6_+_59176470 1.13 ENSDART00000161720
serine hydroxymethyltransferase 2 (mitochondrial)
chr21_+_4204860 1.12 ENSDART00000146541
Rap guanine nucleotide exchange factor (GEF) 1b
chr8_+_26410539 1.11 ENSDART00000168780
interferon-related developmental regulator 2
chr21_+_33249478 1.09 ENSDART00000169972
si:ch211-151g22.1
chr5_-_20135679 1.07 ENSDART00000079402
ubiquitin specific peptidase 30
chr25_+_3294150 1.07 ENSDART00000030683
thymopoietin b
chr6_+_40952031 1.06 ENSDART00000189219
POZ (BTB) and AT hook containing zinc finger 1
chr7_+_51795667 1.06 ENSDART00000174201
ENSDART00000073839
solute carrier family 38, member 7
chr6_-_14038804 1.05 ENSDART00000184606
ENSDART00000184609
ets variant 5b
chr11_+_45110865 1.04 ENSDART00000158188
meningioma expressed antigen 5 (hyaluronidase) like
chr20_+_23625387 1.04 ENSDART00000147945
ENSDART00000150497
palladin, cytoskeletal associated protein
chr5_+_37744625 1.04 ENSDART00000014031
D4, zinc and double PHD fingers family 2
chr25_+_17689565 1.03 ENSDART00000171965
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr5_+_31779911 1.03 ENSDART00000098163
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr20_+_1316495 1.02 ENSDART00000064439
nucleoporin 43
chr16_+_29025292 0.98 ENSDART00000148865
ENSDART00000150184
G patch domain containing 4
chr6_+_59991076 0.98 ENSDART00000163575

chr13_+_11439486 0.97 ENSDART00000138312
zinc finger and BTB domain containing 18
chr20_-_44576949 0.97 ENSDART00000148639
UBX domain protein 2A
chr22_-_21897203 0.97 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr23_+_45845159 0.96 ENSDART00000023944
lamin L3
chr20_+_329032 0.96 ENSDART00000036635
FYN proto-oncogene, Src family tyrosine kinase b
chr8_-_4573545 0.94 ENSDART00000127153
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr25_-_32869794 0.93 ENSDART00000162784
transmembrane protein 266
chr16_+_27614989 0.92 ENSDART00000005625
GLI pathogenesis-related 2, like
chr5_+_1515938 0.92 ENSDART00000054057
DDRGK domain containing 1
chr1_+_19764995 0.91 ENSDART00000138276
si:ch211-42i9.8
chr8_+_26410197 0.91 ENSDART00000145836
ENSDART00000053447
interferon-related developmental regulator 2
chr12_+_33320884 0.90 ENSDART00000188988
casein kinase 1, delta b
chr24_-_17389263 0.88 ENSDART00000122757
cullin 1b
chr10_+_21444654 0.88 ENSDART00000140113
ENSDART00000184386
ENSDART00000019252
F-box and WD repeat domain containing 11b
chr16_+_14010242 0.88 ENSDART00000059928
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr6_-_11759860 0.87 ENSDART00000151296
si:ch211-162i14.1
chr9_-_32300783 0.87 ENSDART00000078596
heat shock 60 protein 1
chr9_-_32300611 0.86 ENSDART00000127938
heat shock 60 protein 1
chr23_-_10786400 0.86 ENSDART00000055038
RING1 and YY1 binding protein a
chr23_-_18668836 0.86 ENSDART00000138792
ENSDART00000051182
Rho GTPase activating protein 4b
chr14_-_46832825 0.85 ENSDART00000149571
LIM domain binding 2a
chr19_+_32257472 0.85 ENSDART00000186471
ataxin 1a
chr14_-_34605804 0.85 ENSDART00000144547
actin filament associated protein 1-like 1a
chr18_+_38191346 0.84 ENSDART00000052703
nucleobindin 2b
chr22_-_10541712 0.84 ENSDART00000013933
si:dkey-42i9.4
chr23_-_31266586 0.84 ENSDART00000139746
si:dkey-261l7.2
chr15_-_10455438 0.83 ENSDART00000158958
ENSDART00000192971
ENSDART00000162133
ENSDART00000185071
ENSDART00000192444
ENSDART00000165668
ENSDART00000175825
teneurin transmembrane protein 4
chr18_+_30441740 0.83 ENSDART00000189074
Gse1 coiled-coil protein
chr25_+_16214854 0.83 ENSDART00000109672
ENSDART00000190093
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr15_-_31109760 0.81 ENSDART00000154254
kinase suppressor of ras 1b
chr7_-_41726657 0.81 ENSDART00000099121
ADP-ribosylation factor-like 8
chr5_-_13315726 0.81 ENSDART00000143364
stromal cell-derived factor 2-like 1
chr16_+_33953644 0.80 ENSDART00000164447
ENSDART00000159969
AT rich interactive domain 1Aa (SWI-like)
chr14_+_21828993 0.80 ENSDART00000144367
C-terminal binding protein 1
chr23_+_45845423 0.79 ENSDART00000183404
lamin L3
chr23_-_31810222 0.78 ENSDART00000134319
ENSDART00000139076
HBS1-like translational GTPase
chr3_-_57762247 0.77 ENSDART00000156522
calcium activated nucleotidase 1a
chr19_-_47570672 0.77 ENSDART00000112155
ribonucleotide reductase M2 polypeptide
chr11_-_18015534 0.76 ENSDART00000181953
glutamine-rich 1
chr11_-_45171139 0.76 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
synaptogyrin 2b
chr19_+_15441022 0.76 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr23_+_43718865 0.76 ENSDART00000175192
anaphase promoting complex subunit 10
chr4_-_4834347 0.75 ENSDART00000141803
cytochrome c oxidase assembly factor 6
chr2_-_37312927 0.75 ENSDART00000141214
SKI-like proto-oncogene a
chr5_+_17780475 0.74 ENSDART00000110783
ENSDART00000115227
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr25_+_34862225 0.74 ENSDART00000149782
zgc:194879
chr18_-_20444296 0.74 ENSDART00000132993
kinesin family member 23
chr25_-_17587785 0.73 ENSDART00000073679
ENSDART00000146851
zgc:66449
chr8_-_1219815 0.73 ENSDART00000016800
ENSDART00000149969
zinc finger protein 367
chr1_+_49266886 0.73 ENSDART00000137179
calcyon neuron-specific vesicular protein
chr13_-_36911118 0.73 ENSDART00000048739
tripartite motif containing 9
chr10_+_15454745 0.72 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbb2 interacting protein
chr5_-_24812715 0.72 ENSDART00000140042
ENSDART00000137128
ENSDART00000182415
ENSDART00000190898
adaptor-related protein complex 1, beta 1 subunit
chr16_-_9869056 0.72 ENSDART00000149312
neurocalcin delta a
chr4_-_16658514 0.72 ENSDART00000133837
DENN/MADD domain containing 5B
chr1_+_54124209 0.72 ENSDART00000187730

chr13_-_12021566 0.71 ENSDART00000125430
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr1_+_8508753 0.71 ENSDART00000091683
alkB homolog 5, RNA demethylase
chr16_-_42750295 0.70 ENSDART00000176570
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr13_-_13030851 0.70 ENSDART00000009499
nuclear receptor binding SET domain protein 2
chr7_-_45993416 0.70 ENSDART00000157602
ENSDART00000166983
zgc:101715
chr7_-_38570299 0.70 ENSDART00000143815
cugbp, Elav-like family member 1
chr7_-_73856073 0.70 ENSDART00000181793

chr5_-_29195063 0.69 ENSDART00000109926
mannosidase, alpha, class 1B, member 1b
chr4_+_9055488 0.69 ENSDART00000155385
solute carrier family 41 (magnesium transporter), member 2b
chr14_+_20156477 0.69 ENSDART00000123434
fragile X mental retardation 1
chr2_-_57918314 0.68 ENSDART00000138265
si:dkeyp-68b7.7
chr2_-_31833347 0.67 ENSDART00000109460
nucleolar protein 7
chr5_-_23574234 0.66 ENSDART00000002453
CWC15 spliceosome-associated protein homolog (S. cerevisiae)
chr1_-_8566567 0.66 ENSDART00000114613
pentatricopeptide repeat domain 1
chr16_+_8139515 0.64 ENSDART00000193303
ENSDART00000139432
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr5_+_36781732 0.64 ENSDART00000087191
MAP/microtubule affinity-regulating kinase 4a
chr23_-_18057851 0.64 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
chr5_+_31811662 0.64 ENSDART00000023463
UDP-N-acetylglucosamine pyrophosphorylase 1, like 1
chr23_-_1583193 0.64 ENSDART00000143841
fibronectin type III domain containing 7b
chr9_+_21795917 0.63 ENSDART00000169069
REV1, polymerase (DNA directed)
chr5_-_18911114 0.63 ENSDART00000014434
bri3 binding protein
chr25_-_20666754 0.63 ENSDART00000158418
C-terminal Src kinase
chr16_-_19568795 0.62 ENSDART00000185141
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr23_+_9508538 0.62 ENSDART00000010697
oxysterol binding protein-like 2b
chr12_-_6063328 0.62 ENSDART00000002583
alanyl-tRNA synthetase domain containing 1
chr13_-_8692860 0.62 ENSDART00000058107
multiple coagulation factor deficiency 2
chr12_+_5530247 0.61 ENSDART00000114637
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr9_+_46745348 0.61 ENSDART00000025256
insulin-like growth factor binding protein 2b
chr23_-_19831739 0.61 ENSDART00000125066
HAUS augmin-like complex, subunit 7
chr8_+_104114 0.61 ENSDART00000172101
synuclein, alpha interacting protein
chr13_+_51710725 0.60 ENSDART00000163741
PWWP domain containing 2B
chr2_+_29995590 0.60 ENSDART00000151906
RNA binding motif protein 33b
chr5_+_8964926 0.60 ENSDART00000091397
ENSDART00000164535
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b
chr18_+_6641542 0.60 ENSDART00000160379
C2 calcium-dependent domain containing 5
chr20_-_53176675 0.59 ENSDART00000184013

chr9_-_12885201 0.59 ENSDART00000124957
ankyrin repeat and zinc finger domain containing 1
chr2_+_36620011 0.59 ENSDART00000177428
p21 protein (Cdc42/Rac)-activated kinase 2a
chr17_+_24064014 0.58 ENSDART00000182782
ENSDART00000139063
ENSDART00000132755
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr13_-_18011168 0.58 ENSDART00000144813
membrane-associated ring finger (C3HC4) 8
chr25_-_20666328 0.57 ENSDART00000098076
C-terminal Src kinase
chr24_+_26337623 0.57 ENSDART00000145637
myoneurin
chr19_+_15440841 0.57 ENSDART00000182329
lin-28 homolog A (C. elegans)
chr5_+_58455488 0.57 ENSDART00000038602
ENSDART00000127958
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr10_-_25328814 0.57 ENSDART00000123820
transmembrane protein 135
chr14_-_31694274 0.56 ENSDART00000173353
MAP7 domain containing 3
chr11_+_39107131 0.55 ENSDART00000105140
zgc:112255
chr6_+_46309795 0.55 ENSDART00000154817
si:dkeyp-67f1.1
chr15_+_24746444 0.55 ENSDART00000032306
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1
chr5_+_4016271 0.55 ENSDART00000113627
ENSDART00000105832
ENSDART00000121415
gametogenetin binding protein 2
chr2_-_7185460 0.54 ENSDART00000092078
ring finger and CCCH-type domains 1b
chr14_-_28534563 0.54 ENSDART00000054088
zgc:113364
chr23_-_27505825 0.54 ENSDART00000137229
ENSDART00000013797
ankyrin repeat and SOCS box containing 8
chr24_-_31090948 0.53 ENSDART00000176799
holocytochrome c synthase b
chr23_-_18057553 0.53 ENSDART00000173102
ENSDART00000058742
zgc:92287
chr15_-_47115787 0.53 ENSDART00000192601

chr4_-_25257451 0.53 ENSDART00000142819
transmembrane protein 110, like
chr20_-_15161669 0.53 ENSDART00000080333
ENSDART00000063882
phospholipid phosphatase 6
chr25_-_25619550 0.52 ENSDART00000150400
TBC1 domain family, member 2B
chr12_-_10476448 0.52 ENSDART00000106172
Rac family small GTPase 1a
chr23_+_41831224 0.52 ENSDART00000171885
sterol carrier protein 2b
chr5_+_36768674 0.52 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr3_+_46559639 0.51 ENSDART00000146189
ENSDART00000127832
ENSDART00000151035
ribonucleoprotein, PTB-binding 1
chr13_+_27770424 0.51 ENSDART00000159281
asparaginase like 1
chr1_+_45925365 0.51 ENSDART00000144245
eukaryotic translation initiation factor 5B
chr18_+_5454341 0.51 ENSDART00000192649
DTW domain containing 1
chr13_-_11743973 0.51 ENSDART00000190641
ENSDART00000079310
mannosidase, beta A, lysosomal
chr8_-_46386024 0.50 ENSDART00000136602
ENSDART00000060919
ENSDART00000137472
glutaminyl-tRNA synthetase
chr15_+_34963316 0.50 ENSDART00000153840
si:ch73-95l15.5
chr8_+_387622 0.50 ENSDART00000167361
PYM homolog 1, exon junction complex associated factor
chr22_+_18929412 0.50 ENSDART00000161598
ENSDART00000166650
ENSDART00000015951
ENSDART00000105392
ENSDART00000131131
basigin
chr8_+_14959587 0.50 ENSDART00000138548
ENSDART00000041697
c-abl oncogene 2, non-receptor tyrosine kinase
chr13_+_24263049 0.49 ENSDART00000135992
ENSDART00000088005
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr15_-_4568154 0.49 ENSDART00000155254
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr14_+_30774032 0.49 ENSDART00000139552
atlastin 3
chr9_-_41025062 0.49 ENSDART00000002053
PMS1 homolog 1, mismatch repair system component

Network of associatons between targets according to the STRING database.

First level regulatory network of myog

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 1.7 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.4 1.8 GO:0060074 synapse maturation(GO:0060074)
0.4 1.7 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.4 1.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.4 1.9 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.3 4.0 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.3 3.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 1.1 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.2 1.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.2 0.7 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.2 0.6 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.2 0.8 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.2 0.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.9 GO:1990592 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.2 0.7 GO:0061113 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.2 0.8 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 0.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 0.2 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.2 2.1 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 0.9 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 1.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.8 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.8 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.5 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.7 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.5 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 2.1 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 2.8 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 1.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.6 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 1.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.7 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.5 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 0.5 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 1.1 GO:0035108 limb morphogenesis(GO:0035108)
0.1 0.7 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.5 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.1 1.7 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 3.5 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.3 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 1.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.3 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.3 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.1 0.3 GO:0035973 aggrephagy(GO:0035973)
0.1 0.3 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 1.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.5 GO:0030728 ovulation(GO:0030728)
0.1 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.4 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.5 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.5 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.7 GO:1903076 regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.1 0.3 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 1.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.8 GO:0032094 response to food(GO:0032094)
0.1 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.7 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 0.3 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.1 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.3 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 0.4 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 1.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.2 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.0 0.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:1902260 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.6 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 1.9 GO:0048599 oocyte development(GO:0048599)
0.0 0.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.4 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.0 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.2 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 1.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.9 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 2.2 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.6 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 1.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.0 1.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.3 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.5 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 2.6 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.1 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.1 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.3 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902253) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 1.0 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.1 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.2 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.1 GO:0008645 hexose transport(GO:0008645) glucose transport(GO:0015758)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.0 0.2 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.4 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.6 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.8 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.1 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.0 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.0 1.0 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.2 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:0043967 histone H4 acetylation(GO:0043967)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.2 2.1 GO:0002102 podosome(GO:0002102)
0.1 1.1 GO:0070552 BRISC complex(GO:0070552)
0.1 2.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0035060 brahma complex(GO:0035060)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 1.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.3 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 4.0 GO:0005657 replication fork(GO:0005657)
0.1 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.6 GO:0070652 HAUS complex(GO:0070652)
0.1 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172) multimeric ribonuclease P complex(GO:0030681)
0.1 0.4 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.7 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.5 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 1.5 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 3.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 2.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.7 GO:0045495 pole plasm(GO:0045495)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0008278 cohesin complex(GO:0008278)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 2.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 5.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.9 GO:0032153 cell division site(GO:0032153)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.3 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.8 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.5 3.7 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.5 1.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 1.1 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.4 1.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 0.9 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 1.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 2.6 GO:0043495 protein anchor(GO:0043495)
0.2 2.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.6 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 1.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 0.7 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.2 1.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 2.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.8 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.7 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.6 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.5 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.4 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.3 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.8 GO:0019894 kinesin binding(GO:0019894)
0.1 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.2 GO:0015923 mannosidase activity(GO:0015923)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.6 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.0 0.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 2.6 GO:0046332 SMAD binding(GO:0046332)
0.0 0.6 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.5 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 1.3 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.7 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 2.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.2 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 2.9 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 3.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 0.9 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 3.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 1.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway