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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for myf6
Z-value: 0.85
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Transcription factors associated with myf6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| myf6 | dr11_v1_chr4_+_21717793_21717793 | 0.53 | 2.4e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr23_-_45319592 Show fit | 2.03 |
ENSDART00000189861
|
coiled-coil domain containing 171 |
|
| chr17_-_5769196 Show fit | 1.78 |
ENSDART00000113885
|
si:dkey-100n19.2 |
|
| chr11_-_6001845 Show fit | 1.67 |
ENSDART00000108628
|
anoctamin 8b |
|
| chr13_+_27951688 Show fit | 1.45 |
ENSDART00000050303
|
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) |
|
| chr5_+_42381273 Show fit | 1.44 |
ENSDART00000142387
|
Pim proto-oncogene, serine/threonine kinase, related 58 |
|
| chr6_+_9241121 Show fit | 1.42 |
ENSDART00000064989
|
Pim proto-oncogene, serine/threonine kinase, related 70 |
|
| chr9_-_105135 Show fit | 1.33 |
ENSDART00000180126
|
|
|
| chr7_+_44715224 Show fit | 1.32 |
ENSDART00000184630
|
si:dkey-56m19.5 |
|
| chr5_-_29671586 Show fit | 1.26 |
ENSDART00000098336
|
sperm acrosome associated 9 |
|
| chr10_-_625441 Show fit | 1.26 |
ENSDART00000171171
|
regulatory factor X, 3 (influences HLA class II expression) |
Network of associatons between targets according to the STRING database.
First level regulatory network of myf6
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.0 | GO:0046777 | protein autophosphorylation(GO:0046777) |
| 0.1 | 2.3 | GO:0060287 | epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) |
| 0.1 | 2.0 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.0 | 1.3 | GO:1902667 | regulation of axon guidance(GO:1902667) |
| 0.1 | 1.2 | GO:0001556 | oocyte maturation(GO:0001556) |
| 0.0 | 1.2 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.0 | 1.2 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
| 0.0 | 1.2 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.2 | 1.1 | GO:1901315 | negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.2 | 1.1 | GO:0009136 | ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.0 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.8 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.2 | 1.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 1.3 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 1.3 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.1 | 1.2 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.0 | 1.0 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.2 | 0.9 | GO:0031673 | H zone(GO:0031673) |
| 0.1 | 0.9 | GO:0036156 | inner dynein arm(GO:0036156) |
| 0.1 | 0.9 | GO:0072546 | ER membrane protein complex(GO:0072546) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 9.7 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.4 | 1.4 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.0 | 1.4 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 1.3 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.0 | 1.3 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 1.3 | GO:0008201 | heparin binding(GO:0008201) |
| 0.3 | 1.2 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.2 | 1.1 | GO:0004960 | thromboxane receptor activity(GO:0004960) |
| 0.1 | 1.1 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 1.1 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 1.1 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 1.1 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.0 | 0.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.7 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.0 | 0.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.4 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 0.3 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.3 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.2 | PID CONE PATHWAY | Visual signal transduction: Cones |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.2 | 1.1 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.1 | 0.9 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.9 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 0.9 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.6 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 0.5 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.5 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |