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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for lmx1ba+lmx1bb_lmx1al

Z-value: 0.51

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Transcription factors associated with lmx1ba+lmx1bb_lmx1al

Gene Symbol Gene ID Gene Info
ENSDARG00000068365 LIM homeobox transcription factor 1, beta b
ENSDARG00000104815 LIM homeobox transcription factor 1, beta a
ENSDARG00000077915 LIM homeobox transcription factor 1, alpha-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lmx1aldr11_v1_chr3_+_52806347_528064410.832.2e-05Click!
lmx1bbdr11_v1_chr8_-_33381430_333814300.418.8e-02Click!
lmx1badr11_v1_chr5_-_5035683_50356830.253.1e-01Click!

Activity profile of lmx1ba+lmx1bb_lmx1al motif

Sorted Z-values of lmx1ba+lmx1bb_lmx1al motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_6954162 1.46 ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr16_-_42056137 1.35 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr20_-_23426339 1.01 ENSDART00000004625
zygote arrest 1
chr24_+_40860320 0.96 ENSDART00000161351
golgi reassembly stacking protein 1b
chr22_-_547748 0.95 ENSDART00000037455
ENSDART00000140101
cyclin D3
chr23_+_31913292 0.93 ENSDART00000136910
armadillo repeat containing 1, like
chr10_-_43771447 0.88 ENSDART00000052307
arrestin domain containing 3b
chr11_-_41853874 0.83 ENSDART00000002556
MRT4 homolog, ribosome maturation factor
chr23_+_39695827 0.83 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr4_+_72723304 0.78 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
RAB3A interacting protein (rabin3)
chr18_+_19456648 0.78 ENSDART00000079695
zwilch kinetochore protein
chr16_+_33902006 0.76 ENSDART00000161807
ENSDART00000159474
guanine nucleotide binding protein-like 2 (nucleolar)
chr22_+_38037530 0.69 ENSDART00000012212
COMM domain containing 2
chr24_-_35561672 0.65 ENSDART00000058564
minichromosome maintenance complex component 4
chr15_+_34988148 0.64 ENSDART00000076269
coiled-coil domain containing 105
chr18_-_19456269 0.64 ENSDART00000060363
ribosomal protein L4
chr20_-_52338782 0.64 ENSDART00000109735
ENSDART00000132941
si:ch1073-287p18.1
chr22_-_2937503 0.63 ENSDART00000092991
ENSDART00000131110
phosphatidylinositol glycan anchor biosynthesis, class X
chr1_-_18811517 0.61 ENSDART00000142026
si:dkey-167i21.2
chr3_+_17537352 0.61 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr18_+_3037998 0.58 ENSDART00000185844
ENSDART00000162657
ribosomal protein S3
chr4_+_22480169 0.58 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr14_-_2933185 0.56 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
chr13_+_4225173 0.55 ENSDART00000058242
ENSDART00000143456
male-enhanced antigen 1
chr11_-_38533505 0.54 ENSDART00000113894
solute carrier family 45, member 3
chr10_-_26512993 0.54 ENSDART00000188549
ENSDART00000193316
si:dkey-5g14.1
chr1_-_46875493 0.51 ENSDART00000115081
1-acylglycerol-3-phosphate O-acyltransferase 3
chr20_+_52554352 0.51 ENSDART00000153217
ENSDART00000145230
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr7_+_72003301 0.50 ENSDART00000012918
ENSDART00000182268
ENSDART00000185750
proteasome 26S subunit, non-ATPase 9
chr2_+_16482338 0.50 ENSDART00000143912
F-box protein 36b
chr4_+_9467049 0.49 ENSDART00000012659
zgc:55888
chr10_-_15340362 0.47 ENSDART00000148119
ENSDART00000127277
ENSDART00000154037
ENSDART00000189109
pumilio RNA-binding family member 3
chr24_+_12989727 0.47 ENSDART00000126842
ENSDART00000129309
hypothetical protein FLJ11011-like (H. sapiens)
chr12_-_35830625 0.46 ENSDART00000180028

chr3_+_27798094 0.46 ENSDART00000075100
ENSDART00000151437
calcium regulated heat stable protein 1
chr15_-_4528326 0.44 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr9_-_1702648 0.43 ENSDART00000102934
heterogeneous nuclear ribonucleoprotein A3
chr1_-_13989643 0.43 ENSDART00000191046
E74-like factor 2b (ets domain transcription factor)
chr24_-_38110779 0.42 ENSDART00000147783
c-reactive protein, pentraxin-related
chr14_+_33329420 0.42 ENSDART00000171090
ENSDART00000164062
sosondowah ankyrin repeat domain family d
chr5_+_36850650 0.42 ENSDART00000051186
non-specific cytotoxic cell receptor protein 1
chr2_+_50608099 0.42 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr19_+_43297546 0.41 ENSDART00000168002
lysosomal protein transmembrane 5
chr5_+_57210237 0.40 ENSDART00000167660
praja ring finger ubiquitin ligase 2
chr19_-_13808630 0.38 ENSDART00000166895
ENSDART00000187670
connective tissue growth factor b
chr23_+_355021 0.38 ENSDART00000190738
adaptor-related protein complex 4, beta 1 subunit
chr7_+_7048245 0.36 ENSDART00000001649
actinin alpha 3b
chr25_+_19739665 0.36 ENSDART00000067353
zgc:101783
chr9_-_20372977 0.36 ENSDART00000113418
immunoglobulin superfamily, member 3
chr17_-_13007484 0.36 ENSDART00000156812
si:dkeyp-33b5.4
chr1_+_52929185 0.36 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr11_-_41220794 0.35 ENSDART00000192895
mitochondrial ribosomal protein S16
chr10_-_8053753 0.35 ENSDART00000162289
si:ch211-251f6.7
chr20_+_7584211 0.34 ENSDART00000132481
ENSDART00000127975
ENSDART00000144551
biogenesis of lysosomal organelles complex-1, subunit 2
chr25_-_3867990 0.34 ENSDART00000075663
calcium release activated channel regulator 2B
chr11_+_17984354 0.33 ENSDART00000179986
RNA pseudouridylate synthase domain containing 4
chr19_+_45962016 0.33 ENSDART00000169710
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr24_-_37698796 0.32 ENSDART00000172178
si:ch211-231f6.6
chr13_+_31402067 0.32 ENSDART00000019202
tudor domain containing 9
chr17_+_15433518 0.32 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr23_+_31912882 0.32 ENSDART00000140505
armadillo repeat containing 1, like
chr20_-_31075972 0.32 ENSDART00000122927
si:ch211-198b3.4
chr3_-_16719244 0.31 ENSDART00000055859
polymerase (DNA directed), delta 1, catalytic subunit
chr2_+_19522082 0.30 ENSDART00000146098
Pim proto-oncogene, serine/threonine kinase, related 49
chr2_+_20793982 0.30 ENSDART00000014785
proteoglycan 4a
chr9_-_9415000 0.30 ENSDART00000146210
si:ch211-214p13.9
chr22_+_19552987 0.30 ENSDART00000105315
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr8_+_25034544 0.30 ENSDART00000123300
neugrin, neurite outgrowth associated
chr7_-_67248829 0.30 ENSDART00000192442
zinc finger protein 143a
chr25_-_10791437 0.30 ENSDART00000127054

chr11_+_33818179 0.29 ENSDART00000109418
speckle-type POZ protein-like b
chr21_-_5066462 0.28 ENSDART00000067733
zgc:77838
chr7_+_9873750 0.28 ENSDART00000173348
ENSDART00000172813
lines homolog 1
chr17_+_15433671 0.28 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr1_-_5455498 0.28 ENSDART00000040368
ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr24_+_9412450 0.28 ENSDART00000132724
si:ch211-285f17.1
chr20_-_9095105 0.27 ENSDART00000140792
OMA1 zinc metallopeptidase
chr9_+_8396755 0.27 ENSDART00000043067
zgc:171776
chr13_+_27232848 0.27 ENSDART00000138043
Ras and Rab interactor 2
chr9_-_25181137 0.27 ENSDART00000192624
esterase D/formylglutathione hydrolase
chr9_-_12424791 0.26 ENSDART00000135447
ENSDART00000088199
zgc:162707
chr9_+_50001746 0.26 ENSDART00000058892
solute carrier family 38, member 11
chr12_+_47698356 0.25 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr17_-_31639845 0.25 ENSDART00000154196
zinc finger protein 839
chr21_+_45502621 0.24 ENSDART00000166719
si:dkey-223p19.2
chr3_+_28860283 0.24 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr22_-_19552796 0.24 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
chr12_+_33817327 0.23 ENSDART00000111486
mitochondrial ribosomal protein L43
chr15_-_16177603 0.23 ENSDART00000156352
si:ch211-259g3.4
chr2_+_19633493 0.23 ENSDART00000147989
Pim proto-oncogene, serine/threonine kinase, related 54
chr15_-_21877726 0.23 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr22_-_20166660 0.23 ENSDART00000085913
ENSDART00000188241
BTB (POZ) domain containing 2a
chr22_+_2937485 0.22 ENSDART00000082222
ENSDART00000135507
ENSDART00000143258
centrosomal protein 19
chr7_+_20471315 0.22 ENSDART00000173714
si:dkey-19b23.13
chr20_+_46492175 0.22 ENSDART00000060695
zinc finger CCCH-type containing 14
chr8_+_21353878 0.22 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr15_-_22074315 0.22 ENSDART00000149830
dopamine receptor D2a
chr5_-_67750907 0.22 ENSDART00000172097
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr9_+_37329036 0.22 ENSDART00000131756
solute carrier family 15 (oligopeptide transporter), member 2
chr19_+_7152966 0.22 ENSDART00000080348
bromodomain containing 2a
chr25_+_35913614 0.22 ENSDART00000022437
glucose-6-phosphate isomerase a
chr5_+_36415978 0.22 ENSDART00000084464
family with sequence similarity 155, member B
chr11_-_45138857 0.21 ENSDART00000166501
calcium activated nucleotidase 1b
chr20_-_20930926 0.21 ENSDART00000123909
BTB (POZ) domain containing 6b
chr5_+_42400777 0.21 ENSDART00000183114

chr2_-_19520324 0.19 ENSDART00000079877
Pim proto-oncogene, serine/threonine kinase, related 52
chr25_-_3759322 0.19 ENSDART00000088077
zgc:158398
chr8_-_37249813 0.19 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
RNA binding motif protein 39b
chr11_-_6048490 0.19 ENSDART00000066164
plasmalemma vesicle associated protein b
chr19_+_41464870 0.19 ENSDART00000102778
distal-less homeobox 6a
chr11_-_40728380 0.19 ENSDART00000023745
coiled-coil domain containing 114
chr5_-_42661012 0.19 ENSDART00000158339
Pim proto-oncogene, serine/threonine kinase, related 58
chr2_+_37227011 0.18 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr11_+_35050253 0.18 ENSDART00000124800
family with sequence similarity 212, member Aa
chr2_+_36721357 0.18 ENSDART00000019063
programmed cell death 10b
chr20_-_45060241 0.18 ENSDART00000185227
kelch-like family member 29
chr6_+_52350443 0.18 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr9_-_41077934 0.18 ENSDART00000100342
ankyrin and armadillo repeat containing
chr19_-_42391383 0.18 ENSDART00000110075
ENSDART00000087002
pleckstrin homology domain containing, family O member 1a
chr2_+_14992879 0.18 ENSDART00000137546
Pim proto-oncogene, serine/threonine kinase, related 55
chr17_-_42492668 0.17 ENSDART00000183946

chr25_+_3035384 0.17 ENSDART00000184219
ENSDART00000149360
mannose phosphate isomerase
chr10_+_43039947 0.17 ENSDART00000193434
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr2_+_19578446 0.17 ENSDART00000164758
Pim proto-oncogene, serine/threonine kinase, related 50
chr6_-_8311044 0.17 ENSDART00000129674
solute carrier family 44 (choline transporter), member 2
chr11_-_37997419 0.17 ENSDART00000102870
solute carrier family 41 (magnesium transporter), member 1
chr7_-_30174882 0.17 ENSDART00000110409
FERM domain containing 5
chr9_-_31278048 0.17 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr14_-_24761132 0.17 ENSDART00000146299
slit homolog 3 (Drosophila)
chr10_-_11261386 0.16 ENSDART00000189946
polypyrimidine tract binding protein 3
chr8_-_37249991 0.16 ENSDART00000189275
ENSDART00000178556
RNA binding motif protein 39b
chr5_-_41494831 0.16 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr10_+_11767791 0.16 ENSDART00000092047
peptidylprolyl isomerase domain and WD repeat containing 1
chr17_+_24722646 0.16 ENSDART00000138356
mitochondrial fission regulator 1-like
chr6_-_51386656 0.16 ENSDART00000154732
ENSDART00000177990
ENSDART00000184928
ENSDART00000180197
protein tyrosine phosphatase, receptor type, t
chr22_-_382955 0.16 ENSDART00000082406
olfactory receptor class A related 3
chr18_-_14677936 0.16 ENSDART00000111995
si:dkey-238o13.4
chr20_-_20931197 0.16 ENSDART00000152726
BTB (POZ) domain containing 6b
chr17_-_29119362 0.16 ENSDART00000104204
forkhead box G1a
chr25_-_27621268 0.15 ENSDART00000146205
ENSDART00000073511
hyaluronoglucosaminidase 6
chr6_+_3280939 0.15 ENSDART00000151359
lysine (K)-specific demethylase 4A, genome duplicate a
chr3_+_13929860 0.15 ENSDART00000164179
synaptonemal complex central element protein 2
chr13_+_22295905 0.15 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr5_-_12219572 0.15 ENSDART00000167834
nitric oxide synthase 1 (neuronal)
chr22_-_15578402 0.15 ENSDART00000062986
hematopoietic SH2 domain containing
chr11_+_17984167 0.15 ENSDART00000020283
ENSDART00000188329
RNA pseudouridylate synthase domain containing 4
chr1_-_31171242 0.15 ENSDART00000190294
potassium voltage-gated channel, KQT-like subfamily, member 5b
chr5_+_66433287 0.15 ENSDART00000170757
kinetochore associated 1
chr21_-_40676224 0.14 ENSDART00000162623
aristaless related homeobox b
chr7_-_6445129 0.14 ENSDART00000172825
Histone H3.2
chr1_-_10821584 0.14 ENSDART00000167452
ENSDART00000162137
cytokine receptor family member B15
chr20_+_18551657 0.14 ENSDART00000147001
si:dkeyp-72h1.1
chr9_+_34641237 0.14 ENSDART00000133996
short stature homeobox
chr9_-_51436377 0.14 ENSDART00000006612
T-box, brain, 1b
chr10_-_32494304 0.14 ENSDART00000028161
UV radiation resistance associated gene
chr16_-_55028740 0.14 ENSDART00000156368
ENSDART00000161704
zgc:114181
chr4_-_16334362 0.14 ENSDART00000101461
epiphycan
chr12_-_6880694 0.14 ENSDART00000171846
protocadherin-related 15b
chr20_-_14925281 0.14 ENSDART00000152641
dynamin 3a
chr6_+_41191482 0.14 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr9_+_38163876 0.14 ENSDART00000137955
cytoplasmic linker associated protein 1a
chr16_-_42894628 0.14 ENSDART00000045600
hemochromatosis type 2
chr21_+_42226113 0.14 ENSDART00000170362
gamma-aminobutyric acid type A receptor beta2 subunit
chr17_+_43032529 0.14 ENSDART00000055611
ENSDART00000154863
iron-sulfur cluster assembly 2
chr17_-_36896560 0.13 ENSDART00000045287
microtubule-associated protein, RP/EB family, member 3a
chr6_-_20952187 0.13 ENSDART00000074327
insulin-like growth factor binding protein 2a
chr24_+_16985181 0.13 ENSDART00000135580
eukaryotic translation initiation factor 2, subunit 3 gamma
chr23_-_31974060 0.13 ENSDART00000168087

chr24_-_17067284 0.13 ENSDART00000111237
armadillo repeat containing 3
chr17_-_31579715 0.13 ENSDART00000110167
ENSDART00000191092
RNA polymerase II associated protein 1
chr3_+_46635527 0.13 ENSDART00000153971
si:dkey-248g21.1
chr16_+_23303859 0.13 ENSDART00000006093
solute carrier family 50 (sugar efflux transporter), member 1
chr10_-_34871737 0.13 ENSDART00000138755
doublecortin-like kinase 1a
chr23_+_24954951 0.13 ENSDART00000136941
nucleolar protein 9
chr13_-_25720876 0.13 ENSDART00000142404
ENSDART00000146487
si:dkey-192p21.6
chr24_+_21540842 0.12 ENSDART00000091529
WAS protein family, member 3b
chr17_+_10593398 0.12 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mitogen-activated protein kinase binding protein 1
chr18_-_20869175 0.12 ENSDART00000090079
synemin, intermediate filament protein
chr17_+_6625717 0.12 ENSDART00000190753
ENSDART00000181298

chr1_-_44434707 0.12 ENSDART00000110148
crystallin, beta A1, like 2
chr8_+_30112655 0.12 ENSDART00000099027
Fanconi anemia, complementation group C
chr24_+_35787629 0.12 ENSDART00000136721
si:dkeyp-7a3.1
chr13_-_12602920 0.12 ENSDART00000102311
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr9_-_19161982 0.12 ENSDART00000081878
POU class 1 homeobox 1
chr4_+_16885854 0.12 ENSDART00000017726
ethanolamine kinase 1
chr20_+_25586099 0.12 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr16_+_5774977 0.12 ENSDART00000134202
cholecystokinin a
chr22_+_7439186 0.12 ENSDART00000190667
zgc:92041
chr6_-_55254786 0.12 ENSDART00000113805
nuclear factor of activated T cells 2b
chr10_-_32494499 0.12 ENSDART00000129395
UV radiation resistance associated gene
chr3_-_41791178 0.12 ENSDART00000049687
galectin-related inter-fiber protein
chr2_-_30668580 0.12 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr13_+_25449681 0.11 ENSDART00000101328
atonal bHLH transcription factor 7
chr15_-_14552101 0.11 ENSDART00000171169
numb homolog (Drosophila)-like
chr6_+_13117598 0.11 ENSDART00000104744
caspase 8, apoptosis-related cysteine peptidase, like 1
chr25_-_13490744 0.11 ENSDART00000056721
lactate dehydrogenase D
chr21_-_22827548 0.11 ENSDART00000079161
angiopoietin-like 5
chr19_+_20274491 0.11 ENSDART00000090860
ENSDART00000151693
oxidoreductase NAD-binding domain containing 1
chr20_+_539852 0.11 ENSDART00000185994
dermatan sulfate epimerase
chr20_-_14924858 0.11 ENSDART00000047039
dynamin 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of lmx1ba+lmx1bb_lmx1al

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.2 0.6 GO:0042755 eating behavior(GO:0042755)
0.1 0.7 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.8 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 0.5 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 1.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.2 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.0 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.2 GO:0044038 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.0 0.3 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.3 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.2 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.0 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.5 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.6 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.1 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.1 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.0 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.6 GO:0022626 cytosolic ribosome(GO:0022626)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0032190 acrosin binding(GO:0032190)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.5 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 0.1 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0016229 steroid dehydrogenase activity(GO:0016229)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins