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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for junba+junbb

Z-value: 1.86

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Transcription factors associated with junba+junbb

Gene Symbol Gene ID Gene Info
ENSDARG00000074378 JunB proto-oncogene, AP-1 transcription factor subunit a
ENSDARG00000104773 JunB proto-oncogene, AP-1 transcription factor subunit b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
junbadr11_v1_chr1_-_51734524_51734535-0.941.2e-08Click!
junbbdr11_v1_chr3_-_7656059_7656059-0.881.9e-06Click!

Activity profile of junba+junbb motif

Sorted Z-values of junba+junbb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_37478418 5.05 ENSDART00000146103
death-associated protein kinase 3
chr10_-_34915886 4.72 ENSDART00000141201
ENSDART00000002166
cyclin A1
chr13_+_42309688 4.67 ENSDART00000158367
insulin-degrading enzyme
chr7_+_46019780 4.54 ENSDART00000163991
cyclin E1
chr25_-_23052707 4.48 ENSDART00000024633
dual specificity phosphatase 8a
chr17_+_25187226 4.46 ENSDART00000148431
CLN8, transmembrane ER and ERGIC protein
chr12_-_10512911 4.28 ENSDART00000124562
ENSDART00000106163
zgc:152977
chr6_+_13232934 4.09 ENSDART00000089725
INO80 complex subunit Db
chr7_-_26532089 4.08 ENSDART00000121698
SUMO1/sentrin/SMT3 specific peptidase 3b
chr16_-_29387215 3.93 ENSDART00000148787
S100 calcium binding protein A1
chr14_-_41468892 3.88 ENSDART00000173099
ENSDART00000003170
MID1 interacting protein 1, like
chr23_+_19590598 3.87 ENSDART00000170149
sarcolemma associated protein b
chr23_-_10175898 3.79 ENSDART00000146185
keratin 5
chr13_+_51710725 3.75 ENSDART00000163741
PWWP domain containing 2B
chr20_-_36671660 3.67 ENSDART00000134819
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6a
chr8_+_12951155 3.64 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr19_-_874888 3.62 ENSDART00000007206
eomesodermin homolog a
chr4_-_20081621 3.52 ENSDART00000024647
DENN/MADD domain containing 6B
chr22_+_336256 3.47 ENSDART00000019155
B-cell translocation gene 2
chr19_-_25772980 3.44 ENSDART00000052393
par-6 family cell polarity regulator gamma b
chr16_+_10557504 3.40 ENSDART00000091241
si:ch73-22o12.1
chr3_+_32403758 3.38 ENSDART00000156982
si:ch211-195b15.8
chr17_+_32623931 3.36 ENSDART00000144217
cathepsin Ba
chr1_+_36772348 3.33 ENSDART00000109314
Rho GTPase activating protein 10
chr6_+_10333920 3.32 ENSDART00000151667
ENSDART00000151477
cordon-bleu WH2 repeat protein-like 1a
chr6_+_27667359 3.22 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr24_-_21090447 3.22 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
queuine tRNA-ribosyltransferase accessory subunit 2
chr18_-_22094102 3.10 ENSDART00000100904
par-6 family cell polarity regulator alpha
chr3_-_15470944 3.09 ENSDART00000185302
spinster homolog 1 (Drosophila)
chr11_+_2710530 3.08 ENSDART00000132768
ENSDART00000030921
ENSDART00000040147
mitogen-activated protein kinase 14b
chr25_-_34845302 3.02 ENSDART00000039485
GABA(A) receptor-associated protein like 2
chr18_+_8917766 3.02 ENSDART00000145226
si:ch211-233h19.2
chr2_-_37477654 2.96 ENSDART00000193921
death-associated protein kinase 3
chr4_-_12477224 2.94 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
Rho guanine nucleotide exchange factor (GEF) 39
chr1_+_45707219 2.87 ENSDART00000143363
si:ch211-214c7.4
chr2_+_9821757 2.85 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr22_+_30047245 2.84 ENSDART00000142857
ENSDART00000141247
ENSDART00000140015
ENSDART00000040538
adducin 3 (gamma) a
chr6_-_52484566 2.84 ENSDART00000112146
family with sequence similarity 83, member C
chr8_+_12118097 2.83 ENSDART00000081819
endonuclease G
chr14_-_12106603 2.79 ENSDART00000054619
phosphoribosyl pyrophosphate synthetase 1B
chr7_-_20241346 2.78 ENSDART00000173619
ENSDART00000127699
si:ch73-335l21.4
chr25_+_35891342 2.73 ENSDART00000147093
LSM14A mRNA processing body assembly factor a
chr7_+_57088920 2.72 ENSDART00000024076
secretory carrier membrane protein 2, like
chr3_-_40768548 2.71 ENSDART00000004923
SMAD specific E3 ubiquitin protein ligase 1
chr25_+_3104959 2.70 ENSDART00000167130
RAB3A interacting protein (rabin3)-like 1
chr8_-_18613948 2.66 ENSDART00000089172
coproporphyrinogen oxidase
chr14_+_30285613 2.65 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr23_+_19590006 2.63 ENSDART00000021231
sarcolemma associated protein b
chr6_+_40992409 2.63 ENSDART00000151419
transforming growth factor, alpha
chr7_-_51749683 2.61 ENSDART00000083190
histone deacetylase 8
chr11_+_24314148 2.59 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr14_+_41318412 2.58 ENSDART00000064614
XK, Kell blood group complex subunit-related, X-linked
chr23_+_12160900 2.57 ENSDART00000136046
protein phosphatase 1, regulatory subunit 3Da
chr13_+_15816573 2.53 ENSDART00000137061
kinesin light chain 1a
chr10_+_4046448 2.53 ENSDART00000123086
ENSDART00000052268
phosphatidylinositol transfer protein, beta
chr14_+_41318881 2.52 ENSDART00000192137
XK, Kell blood group complex subunit-related, X-linked
chr14_+_41318604 2.52 ENSDART00000167042
XK, Kell blood group complex subunit-related, X-linked
chr1_+_19538299 2.51 ENSDART00000109416
structural maintenance of chromosomes 2
chr17_-_7792376 2.51 ENSDART00000064655
zinc finger and BTB domain containing 2a
chr7_-_69429561 2.50 ENSDART00000127351
ataxin 1-like
chr19_+_14454306 2.49 ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr12_+_19199735 2.48 ENSDART00000066393
pdgfa associated protein 1a
chr11_+_24313931 2.48 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr20_-_53949798 2.46 ENSDART00000153435
protein phosphatase 2, regulatory subunit B', gamma b
chr8_+_54274355 2.46 ENSDART00000067639
transmembrane and coiled-coil domain family 1
chr14_-_763744 2.45 ENSDART00000165856
tripartite motif containing 35-27
chr6_+_112579 2.45 ENSDART00000034505
adaptor-related protein complex 1, mu 2 subunit
chr17_-_22573311 2.45 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exonuclease 1
chr24_+_25822999 2.42 ENSDART00000109809
SH3-domain kinase binding protein 1
chr7_+_57089354 2.42 ENSDART00000140702
secretory carrier membrane protein 2, like
chr2_-_55779927 2.41 ENSDART00000168579

chr6_+_49723289 2.41 ENSDART00000190452
syntaxin 16
chr7_-_50764714 2.39 ENSDART00000110283
IQ motif containing GTPase activating protein 1
chr18_-_30499489 2.38 ENSDART00000033746
GINS complex subunit 2
chr21_-_4849029 2.37 ENSDART00000168930
ENSDART00000151019
notch 1a
chr18_+_16749091 2.36 ENSDART00000061265
ring finger protein 141
chr6_+_3716666 2.35 ENSDART00000041627
Sjogren syndrome antigen B (autoantigen La)
chr20_-_51831657 2.34 ENSDART00000165076
melanoma inhibitory activity family, member 3
chr25_+_753364 2.34 ENSDART00000183804
twinfilin actin binding protein 1
chr2_+_32743807 2.31 ENSDART00000022909
kelch-like family member 18
chr8_-_16674584 2.28 ENSDART00000100727
oxysterol binding protein-like 9
chr8_+_25959940 2.28 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
chr17_+_24320861 2.25 ENSDART00000179858
orthodenticle homeobox 1
chr5_+_28259655 2.24 ENSDART00000087684
non-SMC condensin I complex, subunit H
chr11_-_43226255 2.22 ENSDART00000172929
spectrin, beta, non-erythrocytic 1
chr20_-_51831816 2.20 ENSDART00000060505
melanoma inhibitory activity family, member 3
chr24_-_2423791 2.20 ENSDART00000190402
ras responsive element binding protein 1a
chr11_+_506465 2.19 ENSDART00000082519
Raf-1 proto-oncogene, serine/threonine kinase b
chr25_+_17860798 2.18 ENSDART00000146845
parathyroid hormone 1a
chr3_-_61494840 2.18 ENSDART00000101957
BAI1-associated protein 2-like 1b
chr17_+_25849332 2.16 ENSDART00000191994
acyl-CoA synthetase short chain family member 1
chr2_+_24762567 2.15 ENSDART00000078866
interferon, gamma-inducible protein 30
chr12_+_14079097 2.14 ENSDART00000078033
si:ch211-217a12.1
chr16_+_43077909 2.09 ENSDART00000014140
RUN domain containing 3b
chr4_+_9011825 2.09 ENSDART00000058007
sorting and assembly machinery component 50 homolog, like
chr2_-_37352514 2.09 ENSDART00000140498
ENSDART00000186422
SKI-like proto-oncogene a
chr5_+_26204561 2.08 ENSDART00000137178
MARVEL domain containing 2b
chr1_+_49878000 2.08 ENSDART00000047876
lymphoid enhancer-binding factor 1
chr12_+_38807604 2.05 ENSDART00000155563
ATP-binding cassette, sub-family A (ABC1), member 5
chr14_-_33478963 2.05 ENSDART00000132813
lysosomal-associated membrane protein 2
chr3_-_21137362 2.04 ENSDART00000104051
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr7_+_10562118 2.02 ENSDART00000185188
ENSDART00000168801
zinc finger, AN1-type domain 6
chr17_+_24064014 2.01 ENSDART00000182782
ENSDART00000139063
ENSDART00000132755
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr17_+_50701748 2.00 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermitin family member 2
chr21_+_18907102 2.00 ENSDART00000160185
ENSDART00000190175
ENSDART00000017937
ENSDART00000191546
ENSDART00000130519
ENSDART00000137143
sphingomyelin phosphodiesterase 4
chr19_-_12965020 2.00 ENSDART00000128975
solute carrier family 25 (mitochondrial folate carrier), member 32a
chr13_+_22719789 1.99 ENSDART00000057672
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr23_-_29357764 1.97 ENSDART00000156512
si:ch211-129o18.4
chr4_+_9011448 1.96 ENSDART00000192357
sorting and assembly machinery component 50 homolog, like
chr3_-_25369557 1.96 ENSDART00000055491
SMAD specific E3 ubiquitin protein ligase 2
chr13_+_28785814 1.96 ENSDART00000039028
NSE4 homolog A, SMC5-SMC6 complex component
chr1_-_59240975 1.96 ENSDART00000166170
multivesicular body subunit 12A
chr10_-_28380919 1.94 ENSDART00000183409
ENSDART00000183105
ENSDART00000100207
ENSDART00000185392
ENSDART00000131220
B-cell translocation gene 3
chr1_+_49266886 1.93 ENSDART00000137179
calcyon neuron-specific vesicular protein
chr9_+_50110763 1.93 ENSDART00000162990
cordon-bleu WH2 repeat protein-like 1b
chr3_+_33745014 1.93 ENSDART00000159966
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a
chr10_+_5689510 1.93 ENSDART00000183217
ENSDART00000172632
peptidylglycine alpha-amidating monooxygenase
chr4_-_16628801 1.92 ENSDART00000040708
ENSDART00000064009
caprin family member 2
chr8_+_50190742 1.91 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr11_+_2687395 1.91 ENSDART00000082510
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr5_+_33287611 1.91 ENSDART00000125093
ENSDART00000146759
mediator complex subunit 22
chr23_-_24542952 1.91 ENSDART00000088777
ATPase 13A2
chr2_-_45153531 1.91 ENSDART00000109890
calpain 10
chr11_+_31380495 1.90 ENSDART00000185073
signal-induced proliferation-associated 1 like 2
chr5_-_13315726 1.90 ENSDART00000143364
stromal cell-derived factor 2-like 1
chr3_-_49504023 1.90 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr23_-_17509656 1.90 ENSDART00000148423
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr5_+_20366453 1.89 ENSDART00000193141
coronin, actin binding protein, 1Ca
chr7_+_34549198 1.89 ENSDART00000173784
formin homology 2 domain containing 1
chr5_-_29531948 1.89 ENSDART00000098360
arrestin domain containing 1a
chr24_+_37338169 1.87 ENSDART00000141771
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr16_-_42066523 1.85 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr11_-_27827442 1.83 ENSDART00000121847
ENSDART00000132018
ENSDART00000145744
ENSDART00000134677
ENSDART00000130800
cleavage stimulation factor, 3' pre-RNA, subunit 1
chr3_-_43650189 1.83 ENSDART00000161127
axin 1
chr5_-_25576462 1.83 ENSDART00000165147
si:dkey-229d2.4
chr23_+_24973773 1.83 ENSDART00000047020
caspase 9, apoptosis-related cysteine peptidase
chr15_-_41689981 1.83 ENSDART00000059327
splA/ryanodine receptor domain and SOCS box containing 4b
chr22_-_10539180 1.83 ENSDART00000131217
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr24_+_14801844 1.82 ENSDART00000141620
peptidase inhibitor 15a
chr15_-_8309207 1.82 ENSDART00000143880
ENSDART00000061351
tumor necrosis factor receptor superfamily, member 19
chr25_+_17860962 1.80 ENSDART00000163153
parathyroid hormone 1a
chr1_+_52792439 1.78 ENSDART00000123972
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr5_+_33289057 1.77 ENSDART00000123210
mediator complex subunit 22
chr3_+_19245804 1.77 ENSDART00000134514
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr11_-_44647286 1.76 ENSDART00000169329
ENSDART00000158939
translocase of outer mitochondrial membrane 20b
chr17_+_17764979 1.76 ENSDART00000105013
alkB homolog 1, histone H2A dioxygenase
chr15_+_34963316 1.76 ENSDART00000153840
si:ch73-95l15.5
chr16_-_17347727 1.75 ENSDART00000144392
zyxin
chr8_-_13678415 1.73 ENSDART00000134153
ENSDART00000143331
si:dkey-258f14.3
chr4_-_25515154 1.71 ENSDART00000186524
RNA binding motif protein 17
chr18_+_17493859 1.71 ENSDART00000090754
si:dkey-102f14.5
chr19_-_6840506 1.70 ENSDART00000081568
transcription factor 19 (SC1), like
chr8_+_47683539 1.70 ENSDART00000190701
dipeptidyl-peptidase 9
chr6_-_1587291 1.70 ENSDART00000067592
ENSDART00000178877
zgc:123305
chr25_-_36263115 1.70 ENSDART00000143046
ENSDART00000139002
dihydrouridine synthase 2
chr13_+_534453 1.70 ENSDART00000147909
wu:fc17b08
chr9_-_30259447 1.68 ENSDART00000140585
ENSDART00000145052
ENSDART00000129926
si:dkey-100n23.5
chr4_-_25515513 1.68 ENSDART00000142276
ENSDART00000044043
RNA binding motif protein 17
chr16_-_52540056 1.68 ENSDART00000188304

chr7_+_34549377 1.68 ENSDART00000191814
formin homology 2 domain containing 1
chr16_+_27614989 1.68 ENSDART00000005625
GLI pathogenesis-related 2, like
chr21_+_22558187 1.67 ENSDART00000167599
checkpoint kinase 1
chr9_-_30259295 1.67 ENSDART00000139106
si:dkey-100n23.5
chr8_+_49433663 1.67 ENSDART00000140481
ENSDART00000180714
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr16_-_41535690 1.65 ENSDART00000102662
ribonuclease P/MRP 25 subunit-like
chr13_-_17943135 1.64 ENSDART00000176027
membrane-associated ring finger (C3HC4) 8
chr5_-_20921677 1.64 ENSDART00000158030
si:ch211-225b11.4
chr3_+_40576447 1.62 ENSDART00000083212
fascin actin-bundling protein 1a
chr17_+_30591287 1.62 ENSDART00000154243
si:dkey-190l8.2
chr24_-_40901410 1.61 ENSDART00000170688
WD repeat domain 48a
chr21_-_30166097 1.61 ENSDART00000130676
heparin-binding EGF-like growth factor b
chr19_-_31707892 1.61 ENSDART00000088427
RHO family interacting cell polarization regulator 2
chr8_-_13735572 1.61 ENSDART00000139642
si:dkey-258f14.7
chr16_+_46410520 1.60 ENSDART00000131072
rapunzel 2
chr13_-_23956178 1.60 ENSDART00000133646
phosphatase and actin regulator 2
chr2_+_38055529 1.60 ENSDART00000145642
si:rp71-1g18.1
chr10_+_7593185 1.59 ENSDART00000162617
ENSDART00000162590
ENSDART00000171744
protein phosphatase 2, catalytic subunit, beta isozyme
chr21_-_43398457 1.59 ENSDART00000166530
cyclin I family, member 2
chr13_+_46941930 1.58 ENSDART00000056962
F-box protein 5
chr9_+_33334501 1.57 ENSDART00000006867
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr7_-_51749895 1.57 ENSDART00000175523
ENSDART00000189639
histone deacetylase 8
chr23_-_10745288 1.57 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr7_+_38808027 1.56 ENSDART00000052323
harbinger transposase derived 1
chr2_-_19354622 1.56 ENSDART00000168627
zinc finger, FYVE domain containing 9a
chr13_+_29925397 1.56 ENSDART00000123482
CUE domain containing 2
chr21_-_43398122 1.56 ENSDART00000050533
cyclin I family, member 2
chr24_-_37338162 1.55 ENSDART00000056303
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr11_-_44898129 1.52 ENSDART00000157615
eukaryotic translation initiation factor 4A3
chr9_-_6502491 1.52 ENSDART00000102672
NCK adaptor protein 2a
chr18_-_8380090 1.52 ENSDART00000141581
ENSDART00000081143
selenophosphate synthetase 1
chr13_-_23956361 1.52 ENSDART00000101150
phosphatase and actin regulator 2
chr16_-_12060770 1.52 ENSDART00000183237
ENSDART00000103948
si:ch211-69g19.2
chr25_-_37084032 1.51 ENSDART00000025494
hypoxanthine phosphoribosyltransferase 1, like
chr6_+_33537267 1.51 ENSDART00000040334
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr12_+_33320504 1.50 ENSDART00000021491
casein kinase 1, delta b
chr13_-_23612324 1.50 ENSDART00000136406
ENSDART00000005004
DNA primase subunit 2
chr16_-_41667101 1.50 ENSDART00000084528
ATPase secretory pathway Ca2+ transporting 1
chr10_+_1681518 1.50 ENSDART00000018532
TP53 regulated inhibitor of apoptosis 1
chr15_-_41689684 1.50 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr20_+_9223514 1.49 ENSDART00000023293
potassium channel, subfamily K, member 5b

Network of associatons between targets according to the STRING database.

First level regulatory network of junba+junbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
1.2 3.6 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
1.0 5.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.9 3.7 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.9 5.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.8 2.4 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.7 2.8 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.7 4.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.7 9.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.7 2.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.6 1.9 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.6 5.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.6 1.8 GO:0016584 nucleosome positioning(GO:0016584)
0.5 1.6 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.5 4.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.5 2.0 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.5 1.5 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.5 1.8 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.5 1.8 GO:0052746 inositol phosphorylation(GO:0052746)
0.4 2.1 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.4 1.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.4 5.3 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.4 2.8 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.4 1.6 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.4 1.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.4 1.5 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.4 1.8 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.4 0.4 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.4 2.2 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.4 1.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.4 1.8 GO:0051031 tRNA transport(GO:0051031)
0.4 1.8 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.3 2.7 GO:0034063 stress granule assembly(GO:0034063)
0.3 2.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 3.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.3 1.6 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.3 1.9 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.3 1.6 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.3 3.4 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.3 3.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 1.2 GO:0090299 regulation of neural crest formation(GO:0090299)
0.3 0.9 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.3 1.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 3.1 GO:0090398 cellular senescence(GO:0090398)
0.3 1.7 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 0.8 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.3 2.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 1.9 GO:0071333 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.3 1.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.3 1.6 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.3 1.0 GO:1902808 positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.3 2.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 1.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 12.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.3 4.5 GO:0035459 cargo loading into vesicle(GO:0035459)
0.3 1.0 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.2 1.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 1.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 4.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 0.9 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.2 1.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.2 1.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 2.0 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 1.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 2.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 1.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 0.6 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.2 1.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.2 0.8 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.2 1.3 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 2.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 0.6 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.2 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.9 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 2.9 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.2 2.9 GO:0016926 protein desumoylation(GO:0016926)
0.2 2.3 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 2.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 2.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 1.2 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.2 1.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 2.7 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.2 1.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 2.4 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.2 0.6 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.2 1.2 GO:0021588 cerebellum formation(GO:0021588)
0.2 3.6 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 1.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 0.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 2.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.7 GO:0033152 DNA ligation(GO:0006266) immunoglobulin V(D)J recombination(GO:0033152) DNA ligation involved in DNA repair(GO:0051103)
0.1 1.0 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.8 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 3.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 2.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.8 GO:0001839 neural plate morphogenesis(GO:0001839)
0.1 2.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 3.0 GO:0006298 mismatch repair(GO:0006298)
0.1 2.6 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.5 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 4.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 1.9 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 4.3 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.1 0.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.4 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 3.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 2.5 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.5 GO:0071320 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.8 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.1 0.8 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 3.5 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 2.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 2.0 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 2.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 6.6 GO:0006400 tRNA modification(GO:0006400)
0.1 4.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.8 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 5.1 GO:0055088 lipid homeostasis(GO:0055088)
0.1 2.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 2.1 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 0.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.5 GO:0019859 thymine catabolic process(GO:0006210) valine catabolic process(GO:0006574) thymine metabolic process(GO:0019859)
0.1 0.8 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 0.7 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 3.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.5 GO:0061511 centriole elongation(GO:0061511)
0.1 1.9 GO:0090148 membrane fission(GO:0090148)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 1.1 GO:2000369 positive regulation of Notch signaling pathway(GO:0045747) regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.2 GO:0003403 optic vesicle formation(GO:0003403)
0.1 3.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 2.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.2 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 0.6 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.5 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 2.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.3 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.4 GO:0048532 anatomical structure arrangement(GO:0048532)
0.1 1.1 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.1 2.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.9 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 1.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 1.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.2 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.1 1.8 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.1 5.4 GO:0031101 fin regeneration(GO:0031101)
0.1 1.2 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 1.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 6.4 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.1 0.3 GO:0045932 negative regulation of muscle contraction(GO:0045932)
0.1 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.5 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 1.9 GO:0001841 neural tube formation(GO:0001841)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 3.9 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.9 GO:0051693 actin filament capping(GO:0051693)
0.0 1.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 2.3 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 1.2 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 1.3 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 1.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 2.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 1.9 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0072028 nephron morphogenesis(GO:0072028)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 3.1 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 2.6 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.3 GO:0032418 lysosome localization(GO:0032418)
0.0 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 3.8 GO:0006936 muscle contraction(GO:0006936)
0.0 0.7 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.0 1.0 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 2.7 GO:0006417 regulation of translation(GO:0006417)
0.0 3.0 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 2.4 GO:0009913 epidermal cell differentiation(GO:0009913)
0.0 1.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.9 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 1.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.8 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 1.0 GO:0050684 regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.5 GO:0008272 sulfate transport(GO:0008272)
0.0 0.4 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.7 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.3 GO:0060030 dorsal convergence(GO:0060030)
0.0 1.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.4 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 2.4 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.7 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.0 GO:0022406 membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.4 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
1.1 3.4 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
1.1 4.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.8 4.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.7 2.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.7 2.7 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.5 4.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.5 1.5 GO:1990077 primosome complex(GO:1990077)
0.4 2.2 GO:0008091 spectrin(GO:0008091)
0.4 2.1 GO:0000811 GINS complex(GO:0000811)
0.4 1.6 GO:0060171 stereocilium membrane(GO:0060171)
0.3 3.8 GO:0045095 keratin filament(GO:0045095)
0.3 2.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 2.6 GO:0000796 condensin complex(GO:0000796)
0.3 1.2 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.3 1.8 GO:0016589 NURF complex(GO:0016589)
0.3 2.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.3 1.6 GO:0005845 mRNA cap binding complex(GO:0005845)
0.3 1.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 1.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 0.9 GO:0035339 SPOTS complex(GO:0035339)
0.2 0.7 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.2 4.3 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 1.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.2 GO:0031262 Ndc80 complex(GO:0031262)
0.2 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 1.0 GO:0034657 GID complex(GO:0034657)
0.2 3.4 GO:0000813 ESCRT I complex(GO:0000813)
0.2 3.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 4.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 2.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 1.5 GO:0089701 U2AF(GO:0089701)
0.2 4.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 1.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 0.5 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 1.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742) outer mitochondrial membrane protein complex(GO:0098799)
0.2 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.2 2.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.2 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.1 1.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.0 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 1.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 3.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 2.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.8 GO:0032021 NELF complex(GO:0032021)
0.1 0.7 GO:0035032 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 8.9 GO:0030027 lamellipodium(GO:0030027)
0.1 4.5 GO:0016592 mediator complex(GO:0016592)
0.1 1.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 2.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 3.7 GO:0005811 lipid particle(GO:0005811)
0.1 5.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 3.2 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.9 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 2.4 GO:0090544 BAF-type complex(GO:0090544)
0.1 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 4.4 GO:0055037 recycling endosome(GO:0055037)
0.1 4.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.5 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 2.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 4.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 3.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 4.1 GO:0005925 focal adhesion(GO:0005925)
0.0 1.5 GO:0031902 late endosome membrane(GO:0031902)
0.0 28.3 GO:0005794 Golgi apparatus(GO:0005794)
0.0 2.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.1 GO:0031201 SNARE complex(GO:0031201)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.0 6.0 GO:0005764 lysosome(GO:0005764)
0.0 6.9 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 5.5 GO:0005874 microtubule(GO:0005874)
0.0 2.5 GO:0005912 adherens junction(GO:0005912)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.0 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.9 3.7 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.8 2.4 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.7 3.6 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.7 2.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.7 2.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.7 9.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.6 2.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.5 2.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.5 1.5 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.5 1.9 GO:0016842 amidine-lyase activity(GO:0016842)
0.5 2.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.5 2.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.5 1.4 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.4 4.0 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.4 1.8 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.4 5.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4 1.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 1.9 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.4 1.5 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.4 6.5 GO:0005080 protein kinase C binding(GO:0005080)
0.4 2.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 2.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.4 4.3 GO:0043495 protein anchor(GO:0043495)
0.3 1.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.3 1.9 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.3 2.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.3 0.9 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.3 1.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 1.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 5.0 GO:0003785 actin monomer binding(GO:0003785)
0.3 1.0 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.2 1.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 0.7 GO:1901611 phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.2 1.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.2 5.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 13.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 1.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.0 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.8 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 1.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 5.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 4.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.7 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.2 1.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 2.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 3.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 2.6 GO:2001069 glycogen binding(GO:2001069)
0.2 2.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 0.8 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 2.8 GO:0030552 cAMP binding(GO:0030552)
0.2 1.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 2.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 2.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 0.5 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.2 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 1.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 3.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 1.3 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 2.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 2.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.9 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.9 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 1.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 1.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 5.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.8 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 3.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 4.1 GO:0004707 MAP kinase activity(GO:0004707)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.9 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 1.9 GO:0032190 acrosin binding(GO:0032190)
0.1 1.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 2.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 1.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.3 GO:0051380 norepinephrine binding(GO:0051380)
0.1 4.1 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 2.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.8 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.7 GO:0070628 proteasome binding(GO:0070628)
0.1 1.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.5 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 2.9 GO:0031491 nucleosome binding(GO:0031491)
0.1 1.6 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 4.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 1.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 1.6 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.8 GO:0005048 signal sequence binding(GO:0005048)
0.0 3.2 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 1.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.3 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.3 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 2.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 10.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 2.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.3 GO:0030276 clathrin binding(GO:0030276)
0.0 1.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.9 GO:0004620 phospholipase activity(GO:0004620)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 2.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.6 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 9.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 2.9 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.6 GO:0017069 snRNA binding(GO:0017069)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 3.1 GO:0042393 histone binding(GO:0042393)
0.0 1.3 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.9 GO:0051287 NAD binding(GO:0051287)
0.0 5.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 2.5 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.3 GO:0004518 nuclease activity(GO:0004518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 3.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 1.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 13.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 1.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 3.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 1.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 5.6 PID AURORA B PATHWAY Aurora B signaling
0.1 1.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 2.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 3.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 4.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 2.4 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 4.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.0 9.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 2.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 10.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.3 4.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 4.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 1.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 2.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 2.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 2.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 4.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 1.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 2.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 2.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 5.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 4.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.7 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 3.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 3.2 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.1 1.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 2.9 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 2.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 4.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 2.3 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism