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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxd11a

Z-value: 0.54

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Transcription factors associated with hoxd11a

Gene Symbol Gene ID Gene Info
ENSDARG00000059267 homeobox D11a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd11adr11_v1_chr9_-_1978090_1978090-0.381.2e-01Click!

Activity profile of hoxd11a motif

Sorted Z-values of hoxd11a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_28208973 1.61 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
si:ch73-14h10.2
chr2_-_32738535 1.55 ENSDART00000135293
nuclear receptor binding protein 2a
chr23_+_2666944 1.50 ENSDART00000192861

chr5_+_44805028 1.46 ENSDART00000141198
cathepsin La
chr9_+_33154841 1.37 ENSDART00000132465
dopey family member 2
chr5_+_44805269 1.28 ENSDART00000136965
cathepsin La
chr2_+_16597011 1.22 ENSDART00000160641
ENSDART00000125413
5'-3' exoribonuclease 1
chr14_+_32918172 1.21 ENSDART00000182867
ligand of numb-protein X 2b
chr11_-_25257045 1.17 ENSDART00000130477
snail family zinc finger 1a
chr20_-_49889111 1.04 ENSDART00000058858
kinesin family member 13Bb
chr15_-_44052927 0.99 ENSDART00000166209
wu:fb44b02
chr17_+_14965570 0.99 ENSDART00000066604
G protein-coupled receptor 137c
chr3_-_26183699 0.99 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr7_-_24112484 0.97 ENSDART00000111923
ajuba LIM protein
chr19_-_47571456 0.95 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr20_-_34670236 0.95 ENSDART00000033325
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_-_3366590 0.94 ENSDART00000109428
ENSDART00000175329
si:dkey-46g23.1
chr20_-_29499363 0.93 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
ribonucleotide reductase M2 polypeptide
chr21_-_19918286 0.93 ENSDART00000180816
protein phosphatase 1, regulatory subunit 3B
chr14_+_34490445 0.91 ENSDART00000132193
ENSDART00000148044
wingless-type MMTV integration site family, member 8a
chr24_+_21720304 0.91 ENSDART00000147250
ENSDART00000048273
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr5_-_65662996 0.90 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr15_-_17024779 0.89 ENSDART00000154719
huntingtin interacting protein 1
chr20_-_51831657 0.87 ENSDART00000165076
melanoma inhibitory activity family, member 3
chr20_-_48701593 0.86 ENSDART00000132835
paired box 1b
chr20_-_34028967 0.85 ENSDART00000153408
ENSDART00000033817
SCY1-like, kinase-like 3
chr8_-_25033681 0.84 ENSDART00000003493
nuclear transcription factor Y, alpha, like
chr20_-_51831816 0.82 ENSDART00000060505
melanoma inhibitory activity family, member 3
chr24_+_29912509 0.81 ENSDART00000168422
ferric-chelate reductase 1b
chr11_-_25257595 0.80 ENSDART00000123567
snail family zinc finger 1a
chr3_-_26184018 0.78 ENSDART00000191604
si:ch211-11k18.4
chr2_+_49805892 0.78 ENSDART00000056248
WD repeat domain 48b
chr16_+_38940758 0.76 ENSDART00000102482
ENSDART00000136215
enhancer of yellow 2 homolog (Drosophila)
chr1_+_44173245 0.74 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
catenin (cadherin-associated protein), delta 1
chr19_-_47571797 0.73 ENSDART00000166180
ENSDART00000168134
ribonucleotide reductase M2 polypeptide
chr3_+_39579393 0.70 ENSDART00000055170
ceroid-lipofuscinosis, neuronal 3
chr17_+_13031497 0.70 ENSDART00000115208
F-box protein 33
chr15_+_29024895 0.69 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
chr10_-_10969596 0.67 ENSDART00000092011
exonuclease 3'-5' domain containing 3
chr5_-_29531948 0.66 ENSDART00000098360
arrestin domain containing 1a
chr3_-_30488063 0.66 ENSDART00000055393
ENSDART00000151367
mediator complex subunit 25
chr17_+_17764979 0.65 ENSDART00000105013
alkB homolog 1, histone H2A dioxygenase
chr6_-_37745508 0.64 ENSDART00000078316
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr8_-_2616326 0.64 ENSDART00000027214
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr20_-_14462995 0.63 ENSDART00000152418
ENSDART00000044125
gene rich cluster, C10 gene
chr11_+_19603251 0.63 ENSDART00000005639
THO complex 7
chr7_+_38809241 0.62 ENSDART00000190979
harbinger transposase derived 1
chr1_+_52481332 0.62 ENSDART00000074231
claudin domain containing 1b
chr18_-_12295092 0.61 ENSDART00000033248
family with sequence similarity 107, member B
chr16_-_48428035 0.61 ENSDART00000190554
RAD21 cohesin complex component a
chr2_-_44777592 0.61 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr7_+_10911396 0.60 ENSDART00000167273
ENSDART00000081323
ENSDART00000170655
abhydrolase domain containing 17C
chr14_+_45028062 0.60 ENSDART00000184717
ENSDART00000185481
ATPase phospholipid transporting 8A1
chr5_-_36597612 0.57 ENSDART00000031270
ENSDART00000122098
ras homolog gene family, member Gc
chr6_-_33685325 0.57 ENSDART00000181883
microtubule associated serine/threonine kinase 2
chr9_+_21977383 0.57 ENSDART00000135032
si:dkey-57a22.11
chr6_-_42388608 0.54 ENSDART00000049425
Sec61 translocon alpha 1 subunit, like
chr15_-_16946124 0.54 ENSDART00000154923
huntingtin interacting protein 1
chr23_+_22785375 0.54 ENSDART00000142085
arginine-glutamic acid dipeptide (RE) repeats a
chr10_-_10969444 0.53 ENSDART00000138041
exonuclease 3'-5' domain containing 3
chr21_-_39024754 0.53 ENSDART00000056878
tnf receptor-associated factor 4b
chr16_-_42965192 0.52 ENSDART00000113714
metaxin 1a
chr9_+_38588081 0.52 ENSDART00000031127
ENSDART00000131784
sorting nexin 4
chr11_+_24313931 0.52 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr22_+_10713713 0.51 ENSDART00000122349
hippocampus abundant transcript 1b
chr16_-_28658341 0.50 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr24_-_32025637 0.49 ENSDART00000180448
ENSDART00000159034
Ras suppressor protein 1
chr13_-_37474989 0.49 ENSDART00000114136
WD repeat domain 89
chr18_+_15876385 0.49 ENSDART00000142527
early endosome antigen 1
chr22_+_8979955 0.48 ENSDART00000144005
si:ch211-213a13.1
chr10_+_5234327 0.47 ENSDART00000133927
ENSDART00000063120
serine palmitoyltransferase, long chain base subunit 1
chr2_+_31948352 0.46 ENSDART00000192611
ANKH inorganic pyrophosphate transport regulator b
chr12_-_13650344 0.45 ENSDART00000124364
ENSDART00000124638
ENSDART00000171929
signal transducer and activator of transcription 5b
chr8_+_13364950 0.44 ENSDART00000159760
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr14_+_4276394 0.44 ENSDART00000038301
glucosamine-6-phosphate deaminase 2
chr17_-_29311835 0.43 ENSDART00000104224
tectonin beta-propeller repeat containing 2
chr2_+_22363824 0.41 ENSDART00000163172
heparan sulfate 2-O-sulfotransferase 1a
chr18_-_39188664 0.41 ENSDART00000162983
mitogen-activated protein kinase 6
chr13_-_25745089 0.40 ENSDART00000189333
ENSDART00000147420
sphingosine-1-phosphate lyase 1
chr5_+_20453874 0.40 ENSDART00000124545
ENSDART00000008402
squamous cell carcinoma antigen recognized by T cells 3
chr24_-_36238054 0.40 ENSDART00000155725
transmembrane protein 241
chr3_+_52545400 0.38 ENSDART00000184183
solute carrier family 27 (fatty acid transporter), member 1a
chr8_+_36582728 0.38 ENSDART00000049230
polyglutamine binding protein 1
chr21_-_11970199 0.37 ENSDART00000114524
NOP56 ribonucleoprotein homolog
chr5_+_50913034 0.37 ENSDART00000149787
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr16_-_21903083 0.37 ENSDART00000165849
SET domain, bifurcated 1b
chr17_+_23554932 0.37 ENSDART00000135814
pantothenate kinase 1a
chr8_-_35960987 0.37 ENSDART00000160503
solute carrier family 15 (oligopeptide transporter), member 4
chr15_+_44093286 0.36 ENSDART00000114352
zgc:112998
chr10_-_25328814 0.36 ENSDART00000123820
transmembrane protein 135
chr3_+_52545014 0.35 ENSDART00000018908
solute carrier family 27 (fatty acid transporter), member 1a
chr25_-_34973211 0.34 ENSDART00000045177
cyclin-dependent kinase 10
chr7_-_26076970 0.34 ENSDART00000101120
zgc:92664
chr20_+_25879826 0.33 ENSDART00000018519
zgc:153896
chr19_+_9455218 0.33 ENSDART00000139385
si:ch211-288g17.3
chr3_-_31115601 0.33 ENSDART00000139090
ADP-ribosylation factor-like 6 interacting protein 1
chr21_-_33032715 0.33 ENSDART00000065349
ENSDART00000191502
ENSDART00000149386
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1b
chr25_-_6389713 0.33 ENSDART00000083539
SIN3 transcription regulator family member Aa
chr8_+_44677569 0.33 ENSDART00000191104
G protein-coupled receptor kinase 5 like
chr23_+_43718115 0.33 ENSDART00000149266
ENSDART00000149503
anaphase promoting complex subunit 10
chr5_-_62940851 0.33 ENSDART00000137052
sperm antigen with calponin homology and coiled-coil domains 1
chr10_+_26990095 0.32 ENSDART00000064111
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b
chr24_+_11908480 0.31 ENSDART00000024224
flap structure-specific endonuclease 1
chr10_+_20392656 0.31 ENSDART00000160803
R3H domain and coiled-coil containing 1
chr10_-_36618674 0.31 ENSDART00000135302
remodeling and spacing factor 1b, tandem duplicate 1
chr5_-_57289872 0.30 ENSDART00000189893
ENSDART00000050957
fer (fps/fes related) tyrosine kinase
chr23_-_31969786 0.30 ENSDART00000134550
ORMDL sphingolipid biosynthesis regulator 2
chr13_-_37465524 0.29 ENSDART00000100324
ENSDART00000147336
protein phosphatase 2, regulatory subunit B', epsilon isoform b
chr24_+_11908833 0.29 ENSDART00000178622
flap structure-specific endonuclease 1
chr22_+_1953096 0.29 ENSDART00000166630
ENSDART00000186234
si:dkey-15h8.16
chr5_-_23715861 0.29 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr3_-_31115996 0.29 ENSDART00000058955
ADP-ribosylation factor-like 6 interacting protein 1
chr21_-_32781612 0.28 ENSDART00000031028
CCR4-NOT transcription complex, subunit 6a
chr25_+_33063762 0.28 ENSDART00000189974
talin 2b
chr12_+_23912074 0.28 ENSDART00000152864
supervillin a
chr23_-_43718067 0.27 ENSDART00000015777
ATP-binding cassette, sub-family E (OABP), member 1
chr6_-_31348999 0.27 ENSDART00000153734
DnaJ (Hsp40) homolog, subfamily C, member 6
chr20_-_25709247 0.27 ENSDART00000146711
si:dkeyp-117h8.2
chr7_-_7692992 0.26 ENSDART00000192619
aminoadipate aminotransferase
chr22_-_10158038 0.26 ENSDART00000047444
RanBP-type and C3HC4-type zinc finger containing 1
chr5_-_37881345 0.26 ENSDART00000084819
Rho GTPase activating protein 35b
chr17_+_25519089 0.25 ENSDART00000041721
crystallin beta-gamma domain containing 1a
chr7_-_7692723 0.25 ENSDART00000183352
aminoadipate aminotransferase
chr1_+_2321384 0.25 ENSDART00000157662
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_-_20593778 0.25 ENSDART00000124770
UDP glycosyltransferase 8
chr14_+_30795559 0.23 ENSDART00000006132
cofilin 1
chr2_+_23039041 0.23 ENSDART00000056921
casein kinase 1, gamma 2a
chr7_+_13639473 0.23 ENSDART00000157870
ENSDART00000032899
caseinolytic mitochondrial matrix peptidase chaperone subunit a
chr8_-_10961991 0.23 ENSDART00000139603
tripartite motif containing 33
chr8_-_38317914 0.23 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr1_+_26105141 0.22 ENSDART00000102379
ENSDART00000127154
topoisomerase I binding, arginine/serine-rich a
chr15_-_25527580 0.22 ENSDART00000167005
ENSDART00000157498
hypoxia-inducible factor 1, alpha subunit, like
chr17_+_15788100 0.21 ENSDART00000027667
ras-related GTP binding D
chr20_+_41906960 0.20 ENSDART00000193460
centrosomal protein 85, like
chr17_-_15498275 0.19 ENSDART00000156905
ENSDART00000080661
si:ch211-266g18.10
chr24_+_40529346 0.19 ENSDART00000168548

chr16_+_54829293 0.19 ENSDART00000024729
poly(A) binding protein, cytoplasmic 1a
chr8_+_40477264 0.18 ENSDART00000085559
glucokinase (hexokinase 4)
chr12_-_20658285 0.17 ENSDART00000080888
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr8_+_7740004 0.17 ENSDART00000170184
ENSDART00000187811
FYVE, RhoGEF and PH domain containing 1
chr25_+_28823952 0.17 ENSDART00000067072
nuclear transcription factor Y, beta b
chr2_-_32366287 0.17 ENSDART00000144758
upstream binding transcription factor, like
chr4_-_16836006 0.16 ENSDART00000010777
lactate dehydrogenase Ba
chr8_+_3379815 0.15 ENSDART00000155995
zgc:136963
chr15_+_29727799 0.15 ENSDART00000182006
zgc:153372
chr18_-_15373620 0.15 ENSDART00000031752
regulatory factor X, 4
chr11_-_36009924 0.15 ENSDART00000189959
ENSDART00000167472
ENSDART00000191211
ENSDART00000191662
ENSDART00000191780
ENSDART00000192622
ENSDART00000179911
inositol 1,4,5-trisphosphate receptor, type 1b
chr22_+_2632961 0.15 ENSDART00000106278
zinc finger protein 1173
chr14_+_3071110 0.14 ENSDART00000162445
HMG box domain containing 3
chr17_-_44249720 0.14 ENSDART00000156648
orthodenticle homeobox 2b
chr2_+_35733335 0.14 ENSDART00000113489
RAS protein activator like 2
chr20_-_39367895 0.13 ENSDART00000136476
ENSDART00000021788
ENSDART00000180784
PDZ binding kinase
chr8_+_23521974 0.13 ENSDART00000188130
ENSDART00000129378
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr2_-_40135942 0.12 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
eph receptor A4a
chr4_-_22338906 0.12 ENSDART00000131402
golgin B1
chr14_+_36497250 0.12 ENSDART00000184727
si:dkey-237h12.3
chr16_+_54829574 0.11 ENSDART00000148392
poly(A) binding protein, cytoplasmic 1a
chr25_+_18953575 0.11 ENSDART00000155610
thymine DNA glycosylase, tandem duplicate 2
chr6_+_13083146 0.11 ENSDART00000172158
trans-L-3-hydroxyproline dehydratase
chr5_-_28767573 0.10 ENSDART00000158299
ENSDART00000043466
Tnf receptor-associated factor 2a
chr25_+_18953756 0.10 ENSDART00000154291
thymine DNA glycosylase, tandem duplicate 2
chr18_+_14342326 0.10 ENSDART00000181013
ENSDART00000138372
si:dkey-246g23.2
chr12_+_34854562 0.09 ENSDART00000130366
si:dkey-21c1.4
chr11_+_37049347 0.09 ENSDART00000109235
bicaudal D homolog 2 (Drosophila)
chr17_+_8799661 0.09 ENSDART00000105326
tonsoku-like, DNA repair protein
chr18_-_15559817 0.09 ENSDART00000061681
si:ch211-245j22.3
chr19_-_14191592 0.08 ENSDART00000164594
T-box transcription factor Ta
chr17_-_2690083 0.08 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr13_+_31286076 0.08 ENSDART00000142725
growth differentiation factor 10a
chr19_-_43750108 0.08 ENSDART00000171806
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr3_+_29714775 0.07 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr8_-_13364879 0.07 ENSDART00000063863
coiled-coil domain containing 124
chr17_-_23727978 0.07 ENSDART00000079600
multiple inositol-polyphosphate phosphatase 1a
chr1_+_44711446 0.06 ENSDART00000193481
ENSDART00000003895
structure specific recognition protein 1b
chr2_+_36112273 0.06 ENSDART00000191315
T-cell receptor alpha joining 35
chr16_-_49505275 0.06 ENSDART00000160784
SATB homeobox 1b
chr3_-_19495814 0.06 ENSDART00000162248

chr5_-_31857345 0.05 ENSDART00000112546
protein kinase N3
chr3_+_49097775 0.05 ENSDART00000169185
zgc:123284
chr16_-_10547781 0.05 ENSDART00000166495
g6f-like
chr9_-_31090593 0.03 ENSDART00000089136
G protein-coupled receptor 18
chr15_+_31344472 0.03 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
odorant receptor, family D, subfamily 107, member 1
chr22_+_2207502 0.03 ENSDART00000169162
si:dkeyp-79b7.12
chr19_-_617246 0.03 ENSDART00000062551
cytochrome P450, family 51
chr2_+_19785540 0.03 ENSDART00000149789
polypyrimidine tract binding protein 2b
chr17_-_50355512 0.03 ENSDART00000041685
otoferlin b
chr24_-_11908115 0.03 ENSDART00000184329
transmembrane 9 superfamily member 1
chr10_+_40660772 0.03 ENSDART00000148007
trace amine associated receptor 19l
chr2_-_43196595 0.02 ENSDART00000141087
cAMP responsive element modulator a
chr7_+_19552381 0.02 ENSDART00000169060
si:ch211-212k18.5
chr2_-_30734098 0.02 ENSDART00000133769
retinitis pigmentosa 1 (autosomal dominant)
chr21_-_3770636 0.02 ENSDART00000053596
secretory carrier membrane protein 1
chr1_+_41588170 0.02 ENSDART00000139175
si:dkey-56e3.2
chr13_-_25719628 0.02 ENSDART00000135383
si:dkey-192p21.6
chr22_+_16308806 0.02 ENSDART00000162685
leucine rich repeat containing 39
chr5_+_45140914 0.02 ENSDART00000172702
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_19609638 0.02 ENSDART00000079319
reprimo-like
chr22_-_30999000 0.01 ENSDART00000109841
ssu-2 homolog, tandem duplicate 3
chr4_+_19534833 0.01 ENSDART00000140028
leucine rich repeat containing 4.1
chr6_-_60147517 0.01 ENSDART00000083453
solute carrier family 32 (GABA vesicular transporter), member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd11a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.3 1.0 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.3 0.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 0.9 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 2.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 0.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 0.7 GO:0071072 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.1 2.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.6 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.6 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.9 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.1 1.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.5 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.7 GO:0015809 arginine transport(GO:0015809)
0.1 0.8 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.7 GO:0035459 cargo loading into vesicle(GO:0035459)
0.1 1.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.6 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.5 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 1.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.3 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 2.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.7 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.4 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.2 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 1.8 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.5 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.7 GO:0060021 palate development(GO:0060021)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.4 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.6 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.2 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.3 GO:0033753 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 1.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.8 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.4 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.9 GO:0033339 pectoral fin development(GO:0033339)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 0.9 GO:0097189 apoptotic body(GO:0097189)
0.3 0.9 GO:0031251 PAN complex(GO:0031251)
0.2 1.2 GO:0005784 Sec61 translocon complex(GO:0005784)
0.2 0.8 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.9 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.6 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.5 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.3 GO:0016589 NURF complex(GO:0016589)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 4.8 GO:0005764 lysosome(GO:0005764)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 2.6 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 1.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 0.5 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.2 0.6 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 0.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.4 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 0.7 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 0.5 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.5 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.9 GO:2001069 glycogen binding(GO:2001069)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.2 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.5 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.2 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 1.7 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 0.6 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells