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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for hoxc8a
Z-value: 0.87
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Transcription factors associated with hoxc8a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hoxc8a | dr11_v1_chr23_+_36101185_36101185 | 0.89 | 6.5e-07 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_+_51180938 Show fit | 3.57 |
ENSDART00000169022
|
high mobility group nucleosomal binding domain 2 |
|
| chr17_+_50248152 Show fit | 3.24 |
ENSDART00000153998
|
zinc finger, C2HC-type containing 1C |
|
| chr20_-_7072487 Show fit | 3.20 |
ENSDART00000145954
|
si:ch211-121a2.2 |
|
| chr11_-_40728380 Show fit | 3.14 |
ENSDART00000023745
|
coiled-coil domain containing 114 |
|
| chr5_-_29671586 Show fit | 2.87 |
ENSDART00000098336
|
sperm acrosome associated 9 |
|
| chr5_+_29671681 Show fit | 2.41 |
ENSDART00000043096
|
adenylate kinase 8 |
|
| chr2_+_16482338 Show fit | 2.30 |
ENSDART00000143912
|
F-box protein 36b |
|
| chr20_-_14925281 Show fit | 1.91 |
ENSDART00000152641
|
dynamin 3a |
|
| chr16_+_4497302 Show fit | 1.76 |
ENSDART00000081826
ENSDART00000148096 |
tetratricopeptide repeat domain 29 |
|
| chr20_-_14924858 Show fit | 1.69 |
ENSDART00000047039
|
dynamin 3a |
Network of associatons between targets according to the STRING database.
First level regulatory network of hoxc8a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.7 | GO:0006470 | protein dephosphorylation(GO:0006470) |
| 0.2 | 3.6 | GO:0098884 | postsynaptic neurotransmitter receptor internalization(GO:0098884) |
| 0.0 | 3.5 | GO:0009142 | nucleoside triphosphate biosynthetic process(GO:0009142) |
| 0.5 | 1.5 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.1 | 1.4 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.3 | 1.3 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 0.1 | 1.3 | GO:0051445 | regulation of meiotic cell cycle(GO:0051445) |
| 0.4 | 1.2 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.1 | 1.2 | GO:2001235 | positive regulation of apoptotic signaling pathway(GO:2001235) |
| 0.1 | 1.0 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.6 | GO:0098844 | postsynaptic endocytic zone membrane(GO:0098844) |
| 0.0 | 3.5 | GO:0000785 | chromatin(GO:0000785) |
| 0.3 | 2.9 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.2 | 1.5 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 1.4 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.0 | 1.3 | GO:0043186 | P granule(GO:0043186) |
| 0.0 | 1.2 | GO:0044447 | axoneme part(GO:0044447) |
| 0.0 | 1.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 1.0 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.1 | 0.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.9 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.2 | 3.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.5 | 2.4 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.1 | 1.4 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.3 | 1.3 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.1 | 1.0 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.1 | 0.9 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 0.9 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.8 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 0.7 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.7 | PID MYC PATHWAY | C-MYC pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.8 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.7 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |