Project
PRJNA438478: RNAseq of wild type zebrafish germline
Navigation
Downloads
Results for hoxc6a+hoxc6b
Z-value: 0.82
Motif logo
Transcription factors associated with hoxc6a+hoxc6b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hoxc6b | dr11_v1_chr11_+_2198831_2198831 | -0.90 | 3.2e-07 | Click! |
| hoxc6a | dr11_v1_chr23_+_36115541_36115541 | -0.84 | 1.3e-05 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_54299419 Show fit | 2.59 |
ENSDART00000056089
ENSDART00000193107 |
si:zfos-1505d6.3 |
|
| chr16_+_29509133 Show fit | 2.50 |
ENSDART00000112116
|
cathepsin S, ortholog2, tandem duplicate 1 |
|
| chr20_+_54309148 Show fit | 2.48 |
ENSDART00000099360
|
zona pellucida glycoprotein 2, tandem duplicate 1 |
|
| chr20_+_54304800 Show fit | 2.39 |
ENSDART00000121661
|
zona pellucida glycoprotein 2, tandem duplicate 6 |
|
| chr9_+_54039006 Show fit | 2.35 |
ENSDART00000112441
|
toll-like receptor 7 |
|
| chr25_+_22320738 Show fit | 2.29 |
ENSDART00000073566
|
cytochrome P450, family 11, subfamily A, polypeptide 1 |
|
| chr10_-_34916208 Show fit | 2.01 |
ENSDART00000187371
|
cyclin A1 |
|
| chr24_+_15020402 Show fit | 1.87 |
ENSDART00000148102
|
docking protein 6 |
|
| chr3_+_7808459 Show fit | 1.66 |
ENSDART00000162374
|
hook microtubule-tethering protein 2 |
|
| chr5_-_37103487 Show fit | 1.58 |
ENSDART00000149211
|
interleukin 13 receptor, alpha 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of hoxc6a+hoxc6b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.6 | GO:0031112 | positive regulation of microtubule polymerization or depolymerization(GO:0031112) |
| 0.2 | 2.4 | GO:0000915 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.8 | 2.3 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.1 | 2.1 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.0 | 2.0 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029) |
| 0.0 | 1.7 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.3 | 1.3 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.0 | 1.1 | GO:0021983 | pituitary gland development(GO:0021983) |
| 0.0 | 1.1 | GO:0050821 | protein stabilization(GO:0050821) |
| 0.2 | 1.0 | GO:0000012 | single strand break repair(GO:0000012) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.0 | GO:0097124 | cyclin A2-CDK2 complex(GO:0097124) |
| 0.0 | 1.5 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 1.0 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.9 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.0 | 0.9 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.9 | GO:0030141 | secretory granule(GO:0030141) |
| 0.3 | 0.8 | GO:1990879 | CST complex(GO:1990879) |
| 0.1 | 0.8 | GO:0030891 | VCB complex(GO:0030891) |
| 0.0 | 0.8 | GO:0030496 | midbody(GO:0030496) |
| 0.1 | 0.7 | GO:0001401 | mitochondrial sorting and assembly machinery complex(GO:0001401) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 2.5 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.8 | 2.3 | GO:0016713 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 0.0 | 2.3 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.2 | 2.1 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 2.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.3 | 1.9 | GO:0008118 | N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118) |
| 0.0 | 1.7 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 1.4 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
| 0.3 | 1.3 | GO:0048487 | beta-tubulin binding(GO:0048487) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.4 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.2 | 2.1 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 2.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.2 | 1.6 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.0 | 1.4 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 1.1 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 1.1 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.7 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.4 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.4 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.3 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.2 | 2.3 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 2.0 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 2.0 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.1 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.1 | 1.0 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 0.0 | 0.8 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.7 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.7 | REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway |
| 0.0 | 0.7 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |