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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxc5a

Z-value: 0.60

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Transcription factors associated with hoxc5a

Gene Symbol Gene ID Gene Info
ENSDARG00000070340 homeobox C5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc5adr11_v1_chr23_+_36118738_361187380.391.1e-01Click!

Activity profile of hoxc5a motif

Sorted Z-values of hoxc5a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_20939579 2.23 ENSDART00000152371
ubiquitin specific peptidase 2a
chr4_+_17279966 1.78 ENSDART00000067005
ENSDART00000137487
branched chain amino-acid transaminase 1, cytosolic
chr17_+_15433518 1.52 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr18_+_46382484 1.50 ENSDART00000024202
ENSDART00000142790
dynein assembly factor with WDR repeat domains 1
chr17_+_15433671 1.35 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr5_+_69747417 1.34 ENSDART00000153717
si:ch211-275j6.5
chr17_+_41992054 1.32 ENSDART00000182878
ENSDART00000111537
kizuna centrosomal protein
chr11_-_2838699 1.29 ENSDART00000066189
LHFPL tetraspan subfamily member 5a
chr17_-_39772999 1.27 ENSDART00000155727
Pim proto-oncogene, serine/threonine kinase, related 60
chr15_-_46779934 1.24 ENSDART00000085136
chloride channel 2c
chr2_+_49799470 1.24 ENSDART00000146325
si:ch211-190k17.19
chr2_-_38000276 1.20 ENSDART00000034790
Purkinje cell protein 4 like 1
chr20_-_51355465 1.19 ENSDART00000151620
ENSDART00000151690
ENSDART00000110289
t-complex-associated-testis-expressed 1
chr19_+_43297546 1.19 ENSDART00000168002
lysosomal protein transmembrane 5
chr18_+_7456597 1.18 ENSDART00000142270
telomere repeat binding bouquet formation protein 1
chr5_+_42400777 1.17 ENSDART00000183114

chr5_+_38040407 1.17 ENSDART00000139936
si:dkey-111e8.4
chr9_-_41062412 1.14 ENSDART00000193879
ankyrin and armadillo repeat containing
chr8_+_25569903 1.12 ENSDART00000062375
si:dkey-48j7.3
chr25_+_37293312 1.10 ENSDART00000086737
ENSDART00000161595
si:dkey-234i14.9
chr21_+_45502621 1.08 ENSDART00000166719
si:dkey-223p19.2
chr8_-_13046089 1.05 ENSDART00000137784
si:dkey-208b23.5
chr24_+_12989727 1.05 ENSDART00000126842
ENSDART00000129309
hypothetical protein FLJ11011-like (H. sapiens)
chr3_+_26145013 1.05 ENSDART00000162546
ENSDART00000129561
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr14_-_858985 1.04 ENSDART00000148687
ENSDART00000149375
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr1_+_49668423 1.04 ENSDART00000150880
testis specific, 10
chr18_+_7456888 1.02 ENSDART00000081468
telomere repeat binding bouquet formation protein 1
chr9_+_7732714 1.02 ENSDART00000145853
si:ch1073-349o24.2
chr21_+_11885404 1.01 ENSDART00000092015
DDB1 and CUL4 associated factor 12
chr3_+_60721342 1.00 ENSDART00000157772
forkhead box J1a
chr22_-_36530902 0.99 ENSDART00000056188
info polymerase (RNA) II (DNA directed) polypeptide H
chr10_-_31015535 0.98 ENSDART00000146116
pannexin 3
chr23_+_12134839 0.97 ENSDART00000128551
ENSDART00000141204
tubulin tyrosine ligase-like family, member 9
chr5_-_54672763 0.96 ENSDART00000159009
sperm associated antigen 8
chr20_-_13640598 0.95 ENSDART00000128823
ENSDART00000103394
radial spoke 3 homolog
chr8_-_44586981 0.95 ENSDART00000026831
ENSDART00000113945
radial spoke head 14 homolog
chr4_+_9669717 0.95 ENSDART00000004604
si:dkey-153k10.9
chr5_-_71705191 0.92 ENSDART00000187767
adenylate kinase 1
chr14_+_17397534 0.90 ENSDART00000180162
ENSDART00000129838
ring finger protein 212
chr23_-_19140781 0.89 ENSDART00000143580
si:ch73-381f5.2
chr6_+_6797520 0.88 ENSDART00000150967
si:ch211-85n16.3
chr20_+_21022641 0.88 ENSDART00000152561
ENSDART00000141591
si:dkey-219e20.2
chr9_+_23895711 0.87 ENSDART00000034686
COP9 signalosome subunit 8
chr19_+_31873308 0.86 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
chr14_+_46313396 0.86 ENSDART00000047525
crystallin, beta A1, like 1
chr21_+_45502773 0.84 ENSDART00000160059
ENSDART00000165704
si:dkey-223p19.2
chr9_-_30576522 0.83 ENSDART00000101085
MORC family CW-type zinc finger 3a
chr10_-_43771447 0.83 ENSDART00000052307
arrestin domain containing 3b
chr9_-_24970018 0.83 ENSDART00000026924
dynein, axonemal, heavy chain 7
chr2_+_44571200 0.82 ENSDART00000098132
kelch-like family member 24a
chr15_-_45110011 0.81 ENSDART00000182047
ENSDART00000188662

chr19_+_43969363 0.80 ENSDART00000051712
GATA zinc finger domain containing 1
chr6_+_49551614 0.80 ENSDART00000022581
RAB22A, member RAS oncogene family
chr20_+_25586099 0.79 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr15_-_45246911 0.79 ENSDART00000189557
ENSDART00000185291

chr15_-_18162647 0.79 ENSDART00000012064
PIH1 domain containing 2
chr16_-_42894628 0.79 ENSDART00000045600
hemochromatosis type 2
chr21_+_18292535 0.79 ENSDART00000170205
ENSDART00000169676
ENSDART00000163063
dynein, axonemal, intermediate chain 1, paralog 1
chr19_+_40177246 0.78 ENSDART00000049147
RNA binding motif protein 48
chr1_-_19502322 0.78 ENSDART00000181888
ENSDART00000044030
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr21_-_32301109 0.77 ENSDART00000139890
CDC-like kinase 4b
chr12_-_35944654 0.77 ENSDART00000162579
ENSDART00000164199
dynein, axonemal, intermediate chain 2a
chr23_+_39695827 0.76 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr3_-_39180048 0.76 ENSDART00000049720
cyclin-dependent kinase 21
chr6_-_40842768 0.75 ENSDART00000076160
musculoskeletal, embryonic nuclear protein 1a
chr5_+_42386705 0.73 ENSDART00000143034
Pim proto-oncogene, serine/threonine kinase, related 58
chr5_+_42407962 0.73 ENSDART00000188489

chr22_-_26865361 0.73 ENSDART00000182504
heme oxygenase 2a
chr1_+_33697170 0.72 ENSDART00000131664
NOP2/Sun RNA methyltransferase family member 3
chr7_+_49681040 0.72 ENSDART00000176372
ENSDART00000192172
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr5_+_42393896 0.72 ENSDART00000189550

chr6_-_7720332 0.72 ENSDART00000135945
ribosomal protein SA
chr15_-_39955785 0.72 ENSDART00000154556
mutS homolog 5
chr12_+_47698356 0.72 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr20_+_19512727 0.71 ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr16_-_28856112 0.71 ENSDART00000078543
synaptotagmin XIb
chr5_+_42379517 0.70 ENSDART00000103325
Pim proto-oncogene, serine/threonine kinase, related 59
chr20_+_42881104 0.70 ENSDART00000131338
Pim proto-oncogene, serine/threonine kinase, related 110
chr23_-_42752550 0.70 ENSDART00000187059
si:ch73-217n20.1
chr7_+_23515966 0.70 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr21_-_43015383 0.70 ENSDART00000065097
dihydropyrimidinase-like 3
chr5_-_42661012 0.70 ENSDART00000158339
Pim proto-oncogene, serine/threonine kinase, related 58
chr18_-_48547564 0.70 ENSDART00000138607
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr7_+_73397283 0.69 ENSDART00000174390

chr2_-_1548330 0.68 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr15_+_22267847 0.67 ENSDART00000110665
sperm autoantigenic protein 17
chr8_-_11546175 0.67 ENSDART00000081909
si:ch211-248e11.2
chr20_+_7584211 0.67 ENSDART00000132481
ENSDART00000127975
ENSDART00000144551
biogenesis of lysosomal organelles complex-1, subunit 2
chr14_-_49063157 0.66 ENSDART00000021260
septin 8b
chr3_+_62196672 0.66 ENSDART00000097312
SCO1 cytochrome c oxidase assembly protein
chr1_+_55239710 0.66 ENSDART00000174846
si:ch211-286b5.2
chr23_-_42752387 0.65 ENSDART00000149781
si:ch73-217n20.1
chr7_-_52388734 0.65 ENSDART00000174186
WD repeat domain 93
chr10_+_40324395 0.63 ENSDART00000147205
glycolipid transfer protein b
chr24_-_37955993 0.63 ENSDART00000041805
meteorin, glial cell differentiation regulator
chr7_-_4461104 0.63 ENSDART00000023090
ENSDART00000140770
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr12_+_7497882 0.62 ENSDART00000134608
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr17_+_6625717 0.62 ENSDART00000190753
ENSDART00000181298

chr23_-_23401305 0.62 ENSDART00000078936
hairy-related 9
chr21_-_2299002 0.62 ENSDART00000168712
si:ch73-299h12.6
chr5_-_41494831 0.62 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr12_-_35830625 0.61 ENSDART00000180028

chr9_-_7652792 0.61 ENSDART00000137957
DnaJ (Hsp40) homolog, subfamily B, member 2
chr25_+_20715950 0.60 ENSDART00000180223
ERGIC and golgi 2
chr2_+_33751490 0.59 ENSDART00000145031
si:dkey-31m5.7
chr8_+_31435452 0.59 ENSDART00000145282
selenoprotein P
chr13_+_4409294 0.59 ENSDART00000146437
si:ch211-130h14.4
chr21_-_25801956 0.59 ENSDART00000101219
methyltransferase like 27
chr1_-_669717 0.58 ENSDART00000160564
cysteine/tyrosine-rich 1
chr11_+_30057762 0.58 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr3_+_36284986 0.58 ENSDART00000059533
WD repeat domain, phosphoinositide interacting 1
chr12_+_45200744 0.58 ENSDART00000098932
WW domain binding protein 2
chr9_-_9415000 0.57 ENSDART00000146210
si:ch211-214p13.9
chr3_-_13461056 0.57 ENSDART00000137678
F-box and WD repeat domain containing 9
chr13_-_37620091 0.56 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
chr4_+_22480169 0.56 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr16_+_54780544 0.56 ENSDART00000126646
si:zfos-1192g2.3
chr1_-_5394752 0.56 ENSDART00000103724
ENSDART00000188453
Nedd4 family interacting protein 2
chr16_+_10972733 0.56 ENSDART00000049323
POU class 2 homeobox 2a
chr10_+_26747755 0.56 ENSDART00000100329
coagulation factor IXb
chr2_+_19522082 0.56 ENSDART00000146098
Pim proto-oncogene, serine/threonine kinase, related 49
chr15_-_28200049 0.55 ENSDART00000004200
sterile alpha and TIR motif containing 1
chr2_-_56348727 0.55 ENSDART00000060745
ubiquitin A-52 residue ribosomal protein fusion product 1
chr21_-_8422351 0.55 ENSDART00000055329
ENSDART00000134360
LIM homeobox 2a
chr1_-_54063520 0.55 ENSDART00000171722
single-pass membrane protein with aspartate-rich tail 1b
chr24_+_35787629 0.54 ENSDART00000136721
si:dkeyp-7a3.1
chr5_+_44944778 0.54 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
doublesex and mab-3 related transcription factor 1
chr17_+_51682429 0.54 ENSDART00000004379
nucleolar protein 10
chr9_+_18716485 0.53 ENSDART00000135125
stress-associated endoplasmic reticulum protein family member 2
chr19_-_1855368 0.53 ENSDART00000029646
ribosomal protein, large, P1
chr1_-_22851481 0.53 ENSDART00000054386
quinoid dihydropteridine reductase b1
chr5_+_2815021 0.53 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr6_+_52350443 0.53 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr9_-_21382190 0.52 ENSDART00000110943
ENSDART00000188129
ENSDART00000193876
intraflagellar transport 88 homolog
chr3_+_58833306 0.52 ENSDART00000113223
immunoglobulin light 1 constant 3
chr3_-_40658820 0.52 ENSDART00000191948
ring finger protein 216
chr19_-_3931917 0.52 ENSDART00000162532
MAP7 domain containing 1b
chr22_+_34663328 0.51 ENSDART00000183912
si:ch73-304f21.1
chr1_-_55785722 0.51 ENSDART00000142069
ENSDART00000043933
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr1_-_19845378 0.51 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
glyoxylate reductase/hydroxypyruvate reductase b
chr2_+_38373272 0.50 ENSDART00000113111
proteasome subunit beta 5
chr10_+_6625785 0.50 ENSDART00000148433
si:ch211-57m13.3
chr21_-_18972206 0.50 ENSDART00000146743
Pim proto-oncogene, serine/threonine kinase, related 72
chr20_+_5985329 0.50 ENSDART00000165489
centrosomal protein 128
chr22_-_26865181 0.50 ENSDART00000138311
heme oxygenase 2a
chr16_+_28728347 0.49 ENSDART00000149240
si:dkey-24i24.3
chr13_-_9450210 0.49 ENSDART00000133768
Pim proto-oncogene, serine/threonine kinase, related 152
chr3_-_15999501 0.49 ENSDART00000160668
NME/NM23 nucleoside diphosphate kinase 3
chr14_-_24761132 0.49 ENSDART00000146299
slit homolog 3 (Drosophila)
chr8_-_17167819 0.48 ENSDART00000135042
ENSDART00000143920
mitochondrial ribosomal protein S36
chr22_+_508290 0.48 ENSDART00000135403
NUAK family, SNF1-like kinase, 2
chr5_-_9073433 0.48 ENSDART00000099891
ATP synthase membrane subunit eb
chr14_+_39258569 0.48 ENSDART00000103298
diaphanous-related formin 2
chr5_-_13251907 0.48 ENSDART00000176774
ENSDART00000030553
DNA topoisomerase III beta
chr14_-_6225336 0.48 ENSDART00000111681
highly divergent homeobox
chr6_-_9922266 0.47 ENSDART00000151549
Pim proto-oncogene, serine/threonine kinase, related 73
chr10_-_9410068 0.47 ENSDART00000041382
MORN repeat containing 5
chr10_-_34046757 0.47 ENSDART00000099648
Pim proto-oncogene, serine/threonine kinase, related 149
chr6_-_54179860 0.47 ENSDART00000164283
ribosomal protein S10
chr4_+_57881965 0.47 ENSDART00000162234
si:dkeyp-44b5.4
chr1_+_54037077 0.46 ENSDART00000109386
TRIO and F-actin binding protein a
chr21_+_45841731 0.46 ENSDART00000038657
fatty acid hydroxylase domain containing 2
chr5_-_1203455 0.46 ENSDART00000172177
surfeit gene 4
chr8_-_45760087 0.46 ENSDART00000025620
peptidylprolyl isomerase Aa (cyclophilin A)
chr18_-_48983690 0.46 ENSDART00000182359

chr24_+_32176155 0.45 ENSDART00000003745
vimentin
chr9_-_47472998 0.45 ENSDART00000134480
tensin 1b
chr4_+_22297839 0.45 ENSDART00000077707
LLP homolog, long-term synaptic facilitation (Aplysia)
chr11_-_25733910 0.45 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr25_+_21833287 0.45 ENSDART00000187606
creatine kinase, mitochondrial 1
chr9_-_30555725 0.45 ENSDART00000079222
chromatin assembly factor 1, subunit B
chr1_+_59293873 0.45 ENSDART00000168036
retinol dehydrogenase 8b
chr2_+_9990491 0.45 ENSDART00000011906
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr7_+_26534131 0.44 ENSDART00000173980
si:dkey-62k3.5
chr3_-_53114299 0.44 ENSDART00000109390

chr14_-_413273 0.44 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr21_+_22840246 0.44 ENSDART00000151621
baculoviral IAP repeat containing 2
chr14_-_7137808 0.44 ENSDART00000054803
tRNA phosphotransferase 1
chr2_+_33726862 0.43 ENSDART00000146745
si:dkey-31m5.5
chr6_-_31361546 0.43 ENSDART00000027550
adenylate kinase 4
chr21_+_45223194 0.43 ENSDART00000150902
si:ch73-269m14.3
chr6_+_30091811 0.43 ENSDART00000088403
melanotransferrin
chr1_-_53259746 0.43 ENSDART00000134222
interleukin 15
chr16_+_46205693 0.43 ENSDART00000058385
ENSDART00000168145
bolA family member 1
chr24_-_38657683 0.43 ENSDART00000154843
si:ch1073-164k15.3
chr3_-_12026741 0.43 ENSDART00000132238
cilia and flagella associated protein 70
chr14_-_28001986 0.43 ENSDART00000054115
TSC22 domain family, member 3
chr4_-_9909371 0.42 ENSDART00000102656
si:dkey-22l11.6
chr22_+_19366866 0.42 ENSDART00000137301
si:dkey-21e2.12
chr16_-_41004731 0.42 ENSDART00000102591
si:dkey-201i6.2
chr21_-_13972745 0.42 ENSDART00000143874
AT-hook transcription factor
chr14_+_15257658 0.42 ENSDART00000161625
ENSDART00000193577
si:dkey-77g12.4
si:dkey-203a12.5
chr21_-_19314618 0.42 ENSDART00000188744
glycerol-3-phosphate acyltransferase 3
chr6_+_9427641 0.42 ENSDART00000022620
kalirin RhoGEF kinase b
chr11_-_1509773 0.42 ENSDART00000050762
phosphatase and actin regulator 3b
chr16_-_52916248 0.42 ENSDART00000113931
zinc finger, DHHC-type containing 11
chr10_-_34123733 0.42 ENSDART00000157708
ENSDART00000143954
Pim proto-oncogene, serine/threonine kinase, related 150
chr21_-_22827548 0.42 ENSDART00000079161
angiopoietin-like 5
chr3_-_40896927 0.41 ENSDART00000155279
adaptor-related protein complex 5, zeta 1 subunit
chr16_+_23303859 0.41 ENSDART00000006093
solute carrier family 50 (sugar efflux transporter), member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc5a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0034397 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 1.8 GO:0009098 leucine biosynthetic process(GO:0009098)
0.4 1.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 0.9 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.3 1.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.2 1.2 GO:0006788 heme oxidation(GO:0006788)
0.2 1.0 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 0.8 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 1.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.2 0.6 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.2 0.6 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.2 0.5 GO:0030238 male sex determination(GO:0030238)
0.2 0.7 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.2 0.5 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.2 1.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.0 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 1.1 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 3.8 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.8 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.4 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138)
0.1 0.4 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.3 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.1 0.3 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.4 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.5 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 0.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.7 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.2 GO:0071635 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.7 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108) negative regulation of mesoderm development(GO:2000381)
0.1 0.4 GO:0010159 specification of organ position(GO:0010159)
0.1 0.2 GO:0045601 positive regulation of epithelial cell differentiation(GO:0030858) regulation of endothelial cell differentiation(GO:0045601)
0.1 0.3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 1.3 GO:0006415 translational termination(GO:0006415)
0.1 0.4 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.8 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.2 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 0.6 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024)
0.1 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.2 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618) adenohypophysis morphogenesis(GO:0048855)
0.1 0.4 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.3 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 0.3 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.1 0.2 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.8 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.5 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.2 GO:0015677 copper ion import(GO:0015677)
0.1 1.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.7 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.5 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 1.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.4 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.3 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.4 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.8 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.2 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.5 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.3 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.9 GO:0007129 synapsis(GO:0007129)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0071632 optomotor response(GO:0071632)
0.0 11.9 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.6 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0060114 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.6 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.7 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.8 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.0 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0003210 cardiac atrium formation(GO:0003210)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.6 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.6 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.1 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.0 0.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.3 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0070861 regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.6 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0034205 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0070445 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.8 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0050871 positive regulation of B cell activation(GO:0050871)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.4 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0046144 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.5 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.0 0.1 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 1.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.7 GO:0003341 cilium movement(GO:0003341)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0031673 H zone(GO:0031673)
0.2 0.6 GO:0034515 proteasome storage granule(GO:0034515)
0.2 0.8 GO:0097255 R2TP complex(GO:0097255)
0.2 0.5 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 2.2 GO:0070187 telosome(GO:0070187)
0.1 0.6 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 1.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.4 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.0 GO:0005903 brush border(GO:0005903)
0.1 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0044447 axoneme part(GO:0044447)
0.0 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.8 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 1.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.8 GO:0030286 dynein complex(GO:0030286)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.7 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.7 GO:0031514 motile cilium(GO:0031514)
0.0 0.7 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.8 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 2.9 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.5 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.2 1.0 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 0.5 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.8 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.6 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 1.6 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.6 GO:0008430 selenium binding(GO:0008430)
0.1 0.5 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.6 GO:0050699 WW domain binding(GO:0050699)
0.1 1.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.4 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 0.3 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.2 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.3 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.6 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 1.0 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.9 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.5 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0019107 myristoyltransferase activity(GO:0019107)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 1.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0070915 bioactive lipid receptor activity(GO:0045125) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.3 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.3 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.0 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.0 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling