Project
PRJNA438478: RNAseq of wild type zebrafish germline
Navigation
Downloads
Results for hoxb6a+hoxb6b
Z-value: 1.67
Motif logo
Transcription factors associated with hoxb6a+hoxb6b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hoxb6a | dr11_v1_chr3_+_23703704_23703704 | -0.54 | 2.0e-02 | Click! |
| hoxb6b | dr11_v1_chr12_+_27127139_27127139 | -0.22 | 3.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr13_-_24717365 Show fit | 3.47 |
ENSDART00000137934
ENSDART00000003922 |
ER lipid raft associated 1 |
|
| chr13_-_24717618 Show fit | 3.42 |
ENSDART00000172156
|
ER lipid raft associated 1 |
|
| chr20_-_38787047 Show fit | 2.84 |
ENSDART00000152913
ENSDART00000153430 |
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a |
|
| chr7_+_41812190 Show fit | 2.50 |
ENSDART00000113732
ENSDART00000174137 |
origin recognition complex, subunit 6 |
|
| chr4_-_5775507 Show fit | 2.48 |
ENSDART00000021753
|
cyclin C |
|
| chr5_-_9793273 Show fit | 2.46 |
ENSDART00000158874
|
discoidin domain receptor family, member 2, like |
|
| chr20_-_38787341 Show fit | 2.44 |
ENSDART00000136771
|
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a |
|
| chr21_-_19918286 Show fit | 2.44 |
ENSDART00000180816
|
protein phosphatase 1, regulatory subunit 3B |
|
| chr22_+_11756040 Show fit | 2.38 |
ENSDART00000105808
|
keratin 97 |
|
| chr17_+_16090436 Show fit | 2.29 |
ENSDART00000136059
ENSDART00000138734 |
zinc finger protein 395a |
Network of associatons between targets according to the STRING database.
First level regulatory network of hoxb6a+hoxb6b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.5 | GO:0000377 | RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.5 | 7.0 | GO:0071501 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.1 | 5.1 | GO:0031101 | fin regeneration(GO:0031101) |
| 0.2 | 4.3 | GO:0071218 | response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218) |
| 1.4 | 4.2 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.6 | 4.1 | GO:0046931 | pore complex assembly(GO:0046931) |
| 0.0 | 4.1 | GO:0031098 | stress-activated protein kinase signaling cascade(GO:0031098) |
| 0.2 | 3.9 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.8 | 3.8 | GO:0010828 | positive regulation of glucose transport(GO:0010828) |
| 0.2 | 3.7 | GO:0006491 | N-glycan processing(GO:0006491) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 14.7 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.3 | 7.2 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.1 | 6.6 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 5.7 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 5.3 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.3 | 5.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 5.1 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 5.1 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 4.6 | GO:0000785 | chromatin(GO:0000785) |
| 0.3 | 3.9 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.9 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.1 | 7.2 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 6.8 | GO:0005543 | phospholipid binding(GO:0005543) |
| 0.0 | 5.6 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 5.3 | GO:0042802 | identical protein binding(GO:0042802) |
| 0.3 | 5.2 | GO:2001069 | glycogen binding(GO:2001069) |
| 0.0 | 5.1 | GO:0003712 | transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712) |
| 0.6 | 5.0 | GO:0030619 | U1 snRNA binding(GO:0030619) |
| 0.1 | 5.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 4.8 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 5.5 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.3 | 4.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 3.0 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 2.9 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 2.6 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 2.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 2.4 | PID MYC PATHWAY | C-MYC pathway |
| 0.2 | 2.2 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 2.2 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.9 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.4 | 3.9 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.2 | 3.9 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.2 | 3.9 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.1 | 3.8 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 3.6 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.3 | 2.9 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 2.9 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.3 | 2.7 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.3 | 2.7 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |