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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxb5a+hoxb5b

Z-value: 0.08

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Transcription factors associated with hoxb5a+hoxb5b

Gene Symbol Gene ID Gene Info
ENSDARG00000013057 homeobox B5a
ENSDARG00000054030 homeobox B5b
ENSDARG00000113174 homeobox B5b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb5adr11_v1_chr3_+_23707691_23707691-0.233.5e-01Click!
hoxb5bdr11_v1_chr12_+_27129659_27129659-0.204.4e-01Click!

Activity profile of hoxb5a+hoxb5b motif

Sorted Z-values of hoxb5a+hoxb5b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_29387215 0.08 ENSDART00000148787
S100 calcium binding protein A1
chr22_+_25352530 0.08 ENSDART00000176742
ENSDART00000113186
si:dkey-240e12.6
chr15_-_25099679 0.08 ENSDART00000154628
refilin B
chr19_-_27827744 0.06 ENSDART00000181620
PAP associated domain containing 7
chr20_+_43113465 0.05 ENSDART00000004842
dual specificity phosphatase 23a
chr13_+_534453 0.05 ENSDART00000147909
wu:fc17b08
chr4_+_77966055 0.04 ENSDART00000174203
ENSDART00000130100
ENSDART00000080665
ENSDART00000174317
ENSDART00000190123
zgc:113921
chr2_-_15324837 0.04 ENSDART00000015655
trans-2,3-enoyl-CoA reductase-like 2b
chr17_+_20569806 0.04 ENSDART00000113936
zgc:162183
chr6_+_4255319 0.04 ENSDART00000170351
neurobeachin-like 1
chr5_-_16791223 0.04 ENSDART00000192744
ATPase family, AAA domain containing 1a
chr4_-_77551860 0.04 ENSDART00000188176

chr4_-_77563411 0.04 ENSDART00000186841

chr15_-_684911 0.04 ENSDART00000161685
zgc:171901
chr15_-_29556757 0.04 ENSDART00000060049
heat shock protein 70 family, member 13
chr9_+_6082793 0.03 ENSDART00000192045
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr3_+_54776475 0.03 ENSDART00000142710
si:ch211-74m13.1
chr19_+_43341115 0.03 ENSDART00000145846
ENSDART00000102384
sestrin 2
chr2_+_24317465 0.03 ENSDART00000139339
ENSDART00000136284
mitochondrial ribosomal protein L34
chr11_-_2297832 0.03 ENSDART00000158266
zinc finger protein 740a
chr13_-_44819254 0.03 ENSDART00000131673
si:dkeyp-2e4.8
chr19_+_43341424 0.03 ENSDART00000134815
sestrin 2
chr19_+_15441022 0.03 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr20_+_51730658 0.03 ENSDART00000010271
axin interactor, dorsalization associated
chr9_+_16854121 0.02 ENSDART00000110866
CLN5, intracellular trafficking protein
chr3_+_54776117 0.02 ENSDART00000189047
ENSDART00000115076
si:ch211-74m13.1
chr6_-_19340889 0.02 ENSDART00000181407
MIF4G domain containing a
chr20_+_53181017 0.02 ENSDART00000189692
ENSDART00000177109
FIG4 phosphoinositide 5-phosphatase
chr11_-_44030962 0.02 ENSDART00000171910

chr7_+_62320134 0.02 ENSDART00000012089
stromal interaction molecule 2b
chr10_+_26944418 0.02 ENSDART00000135493
FERM domain containing 8
chr8_+_25962833 0.02 ENSDART00000086583
si:dkey-72l14.4
chr10_+_2684958 0.02 ENSDART00000112019
SET domain containing 9
chr7_+_56889879 0.02 ENSDART00000039810
myosin IXAa
chr17_+_49081828 0.02 ENSDART00000156492
T cell lymphoma invasion and metastasis 2a
chr9_+_48755638 0.02 ENSDART00000047401
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr3_+_39579393 0.02 ENSDART00000055170
ceroid-lipofuscinosis, neuronal 3
chr21_-_9769500 0.01 ENSDART00000170710
Rho GTPase activating protein 24
chr19_+_48060464 0.01 ENSDART00000123163
zgc:85936
chr4_-_25812329 0.01 ENSDART00000146658
transmembrane and coiled-coil domain family 3
chr17_+_15041647 0.01 ENSDART00000108999
sterile alpha motif domain containing 4A
chr4_+_3482312 0.01 ENSDART00000109044
glutamate receptor, metabotropic 8a
chr11_+_24957858 0.01 ENSDART00000145647
sulfatase 2a
chr6_+_54888493 0.01 ENSDART00000113331
neuron navigator 1b
chr13_-_86847 0.01 ENSDART00000158062
polymerase (DNA directed), epsilon 2
chr8_-_43847138 0.01 ENSDART00000148358
adhesion G protein-coupled receptor D1
chr9_-_12034444 0.01 ENSDART00000038651
zinc finger protein 804A
chr15_-_3277635 0.01 ENSDART00000189094
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr2_-_24317240 0.01 ENSDART00000078975
tRNA selenocysteine 1 associated protein 1b
chr5_-_26284276 0.01 ENSDART00000148608
ARVCF, delta catenin family member b
chr5_-_71838520 0.00 ENSDART00000174396

chr7_+_36035432 0.00 ENSDART00000179004
iroquois homeobox 3a
chr15_-_12500938 0.00 ENSDART00000159627
sodium channel, voltage-gated, type IV, beta a
chr2_+_22823952 0.00 ENSDART00000147935
autoimmune regulator
chr7_-_72426484 0.00 ENSDART00000190063
rabphilin 3A homolog (mouse), b
chr22_+_1680628 0.00 ENSDART00000166672
si:dkey-1b17.6
chr5_-_9625459 0.00 ENSDART00000143347
SH2B adaptor protein 3
chr6_-_10927766 0.00 ENSDART00000134327
chemokine (C-C motif) receptor 7
chr24_-_29822913 0.00 ENSDART00000160929
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr22_-_4812755 0.00 ENSDART00000191739

chr8_+_8927870 0.00 ENSDART00000081985
Pim-2 proto-oncogene, serine/threonine kinase
chr22_-_7461603 0.00 ENSDART00000170630

chr13_-_11986754 0.00 ENSDART00000164214
nucleophosmin/nucleoplasmin, 3
chr14_-_43586150 0.00 ENSDART00000113697
eukaryotic translation initiation factor 4ea
chr10_+_35439952 0.00 ENSDART00000006284
HERV-H LTR-associating 2a, tandem duplicate 2
chr22_-_15385442 0.00 ENSDART00000090975
transmembrane protein 264
chr6_-_18992896 0.00 ENSDART00000170228
septin 9b
chr22_+_9049179 0.00 ENSDART00000192625
si:ch211-213a13.2
chr15_-_41458613 0.00 ENSDART00000141496
NLR family CARD domain containing 9
chr19_+_23298037 0.00 ENSDART00000183948
immunity-related GTPase family, f1
chr15_-_2803313 0.00 ENSDART00000060839
transforming growth factor, beta 1a
chr19_+_17642356 0.00 ENSDART00000176431

chr3_-_5413018 0.00 ENSDART00000063138
vitelline membrane outer layer 1 homolog a
chr4_+_38547203 0.00 ENSDART00000171349
si:ch211-209n20.1
chr23_+_3513201 0.00 ENSDART00000092258
spermatogenesis associated 2
chr15_-_952891 0.00 ENSDART00000153780
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr7_+_30867008 0.00 ENSDART00000193106
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr14_-_25078569 0.00 ENSDART00000172802
ENSDART00000173345
ENSDART00000135004
matrin 3-like 1.1
chr1_+_55703120 0.00 ENSDART00000141089
adhesion G protein-coupled receptor E6

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb5a+hoxb5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031005 filamin binding(GO:0031005)