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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxa5a

Z-value: 0.71

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Transcription factors associated with hoxa5a

Gene Symbol Gene ID Gene Info
ENSDARG00000102501 homeobox A5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa5adr11_v1_chr19_+_19759577_197595770.807.6e-05Click!

Activity profile of hoxa5a motif

Sorted Z-values of hoxa5a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_50248152 2.56 ENSDART00000153998
zinc finger, C2HC-type containing 1C
chr13_+_2908764 2.16 ENSDART00000162362
wu:fj16a03
chr10_+_39091353 2.15 ENSDART00000125986
si:ch73-1a9.4
chr2_+_13462305 2.04 ENSDART00000149309
ENSDART00000080900
cilia and flagella associated protein 57
chr18_+_1154189 1.91 ENSDART00000135090
si:ch1073-75f15.2
chr16_-_25085327 1.72 ENSDART00000077661
protease, serine 1
chr11_+_25257022 1.66 ENSDART00000156052
tumor protein p53 inducible nuclear protein 2
chr23_-_42752550 1.65 ENSDART00000187059
si:ch73-217n20.1
chr15_-_28200049 1.59 ENSDART00000004200
sterile alpha and TIR motif containing 1
chr16_-_41059919 1.50 ENSDART00000188803
si:dkey-201i6.8
chr21_-_25618175 1.45 ENSDART00000133512
FOS-like antigen 1b
chr21_+_11885404 1.43 ENSDART00000092015
DDB1 and CUL4 associated factor 12
chr10_+_26973063 1.29 ENSDART00000143162
ENSDART00000186210
transmembrane 7 superfamily member 2
chr25_-_24233884 1.28 ENSDART00000146419
si:dkey-11e23.9
chr25_-_13188214 1.22 ENSDART00000187298
si:ch211-147m6.1
chr16_-_24195252 1.21 ENSDART00000136205
ENSDART00000048599
ENSDART00000161547
ribosomal protein S19
chr2_-_43942595 1.20 ENSDART00000147925
si:ch211-195h23.4
chr11_-_30636163 1.20 ENSDART00000140516
zgc:153665
chr8_+_18830759 1.20 ENSDART00000089079
MPN domain containing
chr3_-_59981476 1.19 ENSDART00000035878
ENSDART00000124038
cerebellar degeneration-related protein 2-like
chr4_-_11403811 1.17 ENSDART00000067272
ENSDART00000140018
Pim proto-oncogene, serine/threonine kinase, related 173
chr6_-_7720332 1.11 ENSDART00000135945
ribosomal protein SA
chr4_+_22480169 1.02 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr3_-_24456451 1.01 ENSDART00000024480
ENSDART00000156814
BAI1-associated protein 2-like 2a
chr5_-_68022631 1.01 ENSDART00000143199
WAS protein family, member 3a
chr13_-_12006007 0.98 ENSDART00000111438
meningioma expressed antigen 5 (hyaluronidase)
chr6_-_7718200 0.97 ENSDART00000189664
ENSDART00000114282
ribosomal protein SA
chr19_-_41052408 0.96 ENSDART00000151120
sarcoglycan, epsilon
chr21_-_2952789 0.96 ENSDART00000182898
zinc finger protein 971
chr16_-_12787029 0.90 ENSDART00000139916
forkhead box J2
chr16_-_35394422 0.89 ENSDART00000180593
si:dkey-34d22.3
chr13_-_23074238 0.86 ENSDART00000143210
serglycin
chr11_-_30634286 0.85 ENSDART00000191019
zgc:153665
chr19_+_712127 0.83 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
formin homology 2 domain containing 3a
chr2_+_31597841 0.79 ENSDART00000162181
si:ch211-106h4.4
chr2_-_20574193 0.79 ENSDART00000190448
si:ch211-267e7.3
chr15_-_47956388 0.79 ENSDART00000116506
si:ch1073-111c8.3
chr22_-_18387059 0.76 ENSDART00000007769
testis-specific serine kinase 6
chr21_-_2299002 0.73 ENSDART00000168712
si:ch73-299h12.6
chr15_-_23692359 0.70 ENSDART00000141618
excision repair cross-complementation group 2
chr3_-_32898626 0.70 ENSDART00000103201
K(lysine) acetyltransferase 7a
chr15_-_15469079 0.69 ENSDART00000132637
ENSDART00000004220
RAB34, member RAS oncogene family a
chr2_+_32826235 0.68 ENSDART00000143127
si:dkey-154p10.3
chr3_-_30061985 0.68 ENSDART00000189583
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr5_-_26181863 0.68 ENSDART00000098500
coiled-coil domain containing 125
chr11_-_30630628 0.68 ENSDART00000103265
zgc:158773
chr13_+_35635672 0.67 ENSDART00000148481
thrombospondin 2a
chr13_-_32626247 0.65 ENSDART00000100663
WD repeat domain 35
chr2_+_6127593 0.64 ENSDART00000184007
fizzy/cell division cycle 20 related 1b
chr21_+_45510448 0.64 ENSDART00000160494
ENSDART00000167914
folliculin interacting protein 1
chr4_-_18851365 0.63 ENSDART00000021782
malonyl CoA:ACP acyltransferase (mitochondrial)
chr13_-_12005429 0.62 ENSDART00000180302
meningioma expressed antigen 5 (hyaluronidase)
chr11_-_8782871 0.62 ENSDART00000158546
si:ch211-51h4.2
chr1_-_11973341 0.60 ENSDART00000159981
ENSDART00000066638
G protein-coupled receptor kinase 4
chr7_-_50395395 0.59 ENSDART00000065868
vacuolar protein sorting 33B
chr17_+_24615091 0.59 ENSDART00000064739
ribosomal protein L13a
chr5_-_20814576 0.58 ENSDART00000098682
ENSDART00000147639
si:ch211-225b11.1
chr23_-_31506854 0.58 ENSDART00000131352
ENSDART00000138625
ENSDART00000133002
EYA transcriptional coactivator and phosphatase 4
chr22_+_19366866 0.58 ENSDART00000137301
si:dkey-21e2.12
chr2_+_38264964 0.55 ENSDART00000182068
dehydrogenase/reductase (SDR family) member 1
chr13_+_27316934 0.54 ENSDART00000164533
eukaryotic translation elongation factor 1 alpha 1a
chr23_-_46034609 0.53 ENSDART00000158712
zgc:65873
chr3_+_32112004 0.52 ENSDART00000105272
zgc:173593
chr23_+_4324625 0.50 ENSDART00000146302
ENSDART00000136792
ENSDART00000135027
ENSDART00000179819
serum/glucocorticoid regulated kinase 2a
chr13_-_8601184 0.50 ENSDART00000045086
protein kinase C, epsilon b
chr7_-_24149670 0.49 ENSDART00000005884
matrix metallopeptidase 14a (membrane-inserted)
chr22_+_37631234 0.48 ENSDART00000007346
proteasome 26S subunit, non-ATPase 1
chr25_-_16057539 0.47 ENSDART00000090388
cytochrome b5 reductase 2
chr6_-_47506351 0.46 ENSDART00000128700
im:7151449
chr2_-_59145027 0.46 ENSDART00000128320

chr1_-_35924495 0.45 ENSDART00000184424
SMAD family member 1
chr23_+_40109353 0.44 ENSDART00000149249
growth hormone releasing hormone receptor, like
chr6_-_9236309 0.44 ENSDART00000160397
ENSDART00000164603
IQ motif containing B1
chr7_+_34290051 0.44 ENSDART00000123498
fin bud initiation factor b
chr10_+_36178713 0.44 ENSDART00000140816
odorant receptor, family D, subfamily 108, member 3
chr3_-_62380146 0.44 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr20_+_52774730 0.42 ENSDART00000014606
phosphatase and actin regulator 1
chr17_-_43391499 0.42 ENSDART00000189280
inositol-tetrakisphosphate 1-kinase b
chr4_-_9852318 0.42 ENSDART00000080702
glycosyltransferase 8 domain containing 2
chr20_-_9095105 0.41 ENSDART00000140792
OMA1 zinc metallopeptidase
chr16_+_25664078 0.41 ENSDART00000154024
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr20_-_29483514 0.40 ENSDART00000062370
actin, alpha, cardiac muscle 1a
chr21_-_4922981 0.40 ENSDART00000191819
ENSDART00000113556
ENSDART00000193269
ENSDART00000182961
potassium channel, subfamily T, member 1
chr1_-_45614481 0.40 ENSDART00000148413
activating transcription factor 7 interacting protein
chr19_+_19600297 0.38 ENSDART00000160134
ENSDART00000183493
3-hydroxyisobutyrate dehydrogenase a
chr1_-_14332283 0.37 ENSDART00000090025
Wolfram syndrome 1a (wolframin)
chr17_-_22324727 0.37 ENSDART00000160341

chr24_-_6078222 0.36 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr5_-_23909934 0.36 ENSDART00000142516
si:ch211-135f11.1
chr22_-_36530902 0.36 ENSDART00000056188
info polymerase (RNA) II (DNA directed) polypeptide H
chr16_+_25664387 0.35 ENSDART00000184394
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
chr18_+_11506561 0.32 ENSDART00000121647
protein arginine methyltransferase 8
chr18_-_40901707 0.32 ENSDART00000139352
forkhead box G1c
chr11_-_42980535 0.32 ENSDART00000181160
ENSDART00000192064

chr12_-_31461412 0.32 ENSDART00000175929
ENSDART00000186342
acyl-CoA synthetase long chain family member 5
chr22_+_1462177 0.32 ENSDART00000164685
si:dkeyp-53d3.5
chr10_+_5025696 0.31 ENSDART00000031165
enolase-phosphatase 1
chr18_-_2433011 0.30 ENSDART00000181922
ENSDART00000193276

chr7_+_6480212 0.30 ENSDART00000173320
si:cabz01036022.1
chr13_+_27316632 0.30 ENSDART00000016121
eukaryotic translation elongation factor 1 alpha 1a
chr14_+_6159162 0.30 ENSDART00000128638
Bernardinelli-Seip congenital lipodystrophy 2, like
chr5_+_66433287 0.29 ENSDART00000170757
kinetochore associated 1
chr5_-_16475682 0.29 ENSDART00000090695
piwi-like RNA-mediated gene silencing 2
chr4_-_10599062 0.27 ENSDART00000048003
tetraspanin 12
chr14_-_413273 0.27 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr8_-_18262149 0.27 ENSDART00000143000
ring finger protein 220b
chr15_+_23799461 0.25 ENSDART00000154885
si:ch211-167j9.4
chr8_+_20950401 0.25 ENSDART00000136484
ENSDART00000131329
ENSDART00000144451
ENSDART00000144929
si:dkeyp-82a1.1
chr2_+_3533117 0.25 ENSDART00000132572
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr22_+_17784414 0.25 ENSDART00000188189
ENSDART00000145260
transmembrane 6 superfamily member 2
chr5_-_25583125 0.25 ENSDART00000031665
ENSDART00000145353
annexin A1a
chr7_+_22585447 0.24 ENSDART00000149144
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr25_-_20523927 0.24 ENSDART00000114448
si:ch211-269c21.2
chr14_-_38826739 0.23 ENSDART00000187633
spindle apparatus coiled-coil protein 1
chr22_-_9896180 0.23 ENSDART00000138343
zinc finger protein 990
chr4_-_30712588 0.23 ENSDART00000142393
si:dkey-16p19.5
chr21_-_25668153 0.23 ENSDART00000192062
transmembrane protein 179B
chr24_-_21404367 0.23 ENSDART00000152093
ATPase phospholipid transporting 8A2
chr10_+_21576909 0.22 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3
chr15_-_42736433 0.22 ENSDART00000154379
si:ch211-181d7.1
chr7_+_42935126 0.22 ENSDART00000157747

chr5_-_67783593 0.21 ENSDART00000010934
calcium-sensing receptor
chr14_-_30540967 0.21 ENSDART00000026907
hairy-related 11
chr19_+_19241372 0.21 ENSDART00000184392
ENSDART00000165008
protein tyrosine phosphatase, non-receptor type 23, b
chr16_+_7242610 0.21 ENSDART00000081477
sorcin
chr9_+_41080029 0.21 ENSDART00000141179
ENSDART00000019289
zgc:136439
chr11_-_38083397 0.20 ENSDART00000086516
ENSDART00000184033
kelch domain containing 8A
chr5_+_59392183 0.19 ENSDART00000082983
ENSDART00000180882
CAP-GLY domain containing linker protein 2
chr4_+_11723852 0.19 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr7_-_6604623 0.19 ENSDART00000172874
potassium inwardly-rectifying channel, subfamily J, member 10a
chr7_+_23577723 0.18 ENSDART00000049885
si:dkey-172j4.3
chr2_-_49978227 0.18 ENSDART00000142835
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1b
chr8_-_4892913 0.18 ENSDART00000126808
immunoglobulin superfamily, member 9b
chr23_+_5490854 0.18 ENSDART00000175403
tubby like protein 1a
chr2_+_37897079 0.17 ENSDART00000141784
telomerase-associated protein 1
chr14_-_10762629 0.17 ENSDART00000061928
fibroblast growth factor 16
chr10_+_8690936 0.17 ENSDART00000144218
si:dkey-27b3.4
chr12_+_7406318 0.17 ENSDART00000152420
BicC family RNA binding protein 1b
chr10_+_17776981 0.15 ENSDART00000141693
chemokine (C-C motif) ligand 19b
chr1_-_20273227 0.15 ENSDART00000146084
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_-_10647307 0.15 ENSDART00000103548
si:dkey-31e10.1
chr6_+_72040 0.14 ENSDART00000122957
crystallin, gamma M4
chr15_+_1372343 0.14 ENSDART00000152285
schwannomin interacting protein 1
chr3_-_36750068 0.13 ENSDART00000173388
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr22_+_1700552 0.13 ENSDART00000166185
zinc finger protein 1154
chr25_-_3627130 0.13 ENSDART00000171863
si:ch211-272n13.3
chr21_+_35327328 0.12 ENSDART00000130626
arginyl-tRNA synthetase
chr8_-_30779101 0.12 ENSDART00000062229
purinergic receptor P2X, ligand-gated ion channel, 7
chr4_-_65037243 0.12 ENSDART00000170059
si:ch211-283l16.1
chr13_+_29771463 0.12 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
paired box 2a
chr13_+_25422009 0.11 ENSDART00000057686
calcium homeostasis modulator 2
chr16_-_48074540 0.11 ENSDART00000187258
ENSDART00000186694
si:ch211-236p22.1
chr13_-_37383625 0.11 ENSDART00000192888
ENSDART00000100322
ENSDART00000138934
potassium voltage-gated channel, subfamily H (eag-related), member 5b
chr8_-_22274222 0.11 ENSDART00000131805
nephronophthisis 4
chr3_+_17346502 0.11 ENSDART00000187786
ENSDART00000131584
si:ch211-210g13.5
chr4_-_14162327 0.10 ENSDART00000138656
si:dkey-234l24.1
chr3_-_18410968 0.10 ENSDART00000041842
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
chr8_-_42594380 0.10 ENSDART00000140126
ENSDART00000135238
ENSDART00000192764
docking protein 2
chr13_-_28688104 0.10 ENSDART00000133827
polycomb group ring finger 6
chr21_+_35327589 0.10 ENSDART00000145191
ENSDART00000132743
arginyl-tRNA synthetase
chr3_+_32365811 0.09 ENSDART00000155967
adaptor-related protein complex 2, alpha 1 subunit
chr11_+_10975481 0.09 ENSDART00000160488
integrin, beta 6
chr2_+_8779164 0.09 ENSDART00000134308
zinc finger, ZZ-type containing 3
chr10_+_16069987 0.08 ENSDART00000043936
multiple EGF-like-domains 10
chr17_+_8542203 0.08 ENSDART00000158873

chr8_-_50287949 0.08 ENSDART00000023639
NK2 transcription factor related 7
chr1_-_11850353 0.08 ENSDART00000033361
tweety family member 3b
chr3_-_9488350 0.07 ENSDART00000186707

chr8_+_43053519 0.07 ENSDART00000147178
prion protein a
chr18_+_38321039 0.07 ENSDART00000132534
ENSDART00000111260
ENSDART00000192806
ALX homeobox 4b
chr3_-_55404985 0.07 ENSDART00000154274
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga
chr12_+_28574863 0.07 ENSDART00000153284
TBK1 binding protein 1
chr7_-_47850702 0.07 ENSDART00000109511
si:ch211-186j3.6
chr21_+_5580948 0.07 ENSDART00000160373
lymphocyte antigen 6 family member M7
chr9_+_52492639 0.06 ENSDART00000078939
membrane-associated ring finger (C3HC4) 4
chr15_-_15230264 0.06 ENSDART00000155400
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr16_-_23379464 0.06 ENSDART00000045891
tripartite motif containing 46a
chr19_+_21919856 0.05 ENSDART00000187306
ENSDART00000138544
galanin receptor 1a
chr21_+_11509461 0.05 ENSDART00000134620
ectonucleoside triphosphate diphosphohydrolase 2b
chr18_+_13300768 0.05 ENSDART00000137506
si:ch211-260p9.3
chr14_-_2322484 0.05 ENSDART00000167806
si:ch73-379j16.2
chr16_-_11962959 0.04 ENSDART00000135379
CD4-2 molecule, tandem duplicate 2
chr9_-_390874 0.04 ENSDART00000165324
si:dkey-11f4.7
chr5_+_38913621 0.04 ENSDART00000137112
Fraser extracellular matrix complex subunit 1
chr7_-_33961551 0.04 ENSDART00000100104
SKI family transcriptional corepressor 1a
chr7_-_69983462 0.04 ENSDART00000123380
potassium voltage-gated channel interacting protein 4
chr4_-_14173138 0.03 ENSDART00000142487
si:dkey-234l24.7
chr1_-_9940494 0.03 ENSDART00000138726
transmembrane protein 8A
chr17_-_43558494 0.02 ENSDART00000103830
5'-nucleotidase, cytosolic IAb
chr7_-_41964877 0.02 ENSDART00000092351
ENSDART00000193395
ENSDART00000187947
neuropilin (NRP) and tolloid (TLL)-like 2b
chr7_+_2236317 0.01 ENSDART00000075859
zgc:172065
chr6_-_39489190 0.01 ENSDART00000151299
sodium channel, voltage gated, type VIII, alpha subunit b
chr9_+_21843915 0.01 ENSDART00000101977
potassium channel tetramerisation domain containing 12.1
chr15_-_1745408 0.01 ENSDART00000182311
syntaxin 1A (brain)
chr23_-_44965582 0.01 ENSDART00000163367
transferrin receptor 2
chr24_+_35981471 0.01 ENSDART00000157373
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr23_+_21414005 0.01 ENSDART00000144686
intermediate filament family orphan 2a
chr15_+_8335600 0.00 ENSDART00000190066
ENSDART00000152603
egl-9 family hypoxia-inducible factor 2
chr4_+_57099307 0.00 ENSDART00000131654
si:ch211-238e22.2
chr17_+_6828550 0.00 ENSDART00000153777
si:ch73-242m19.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa5a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.2 0.6 GO:0044068 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.1 3.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 1.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.6 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.3 GO:2000191 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.1 0.3 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.7 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.1 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.3 GO:0000966 RNA 5'-end processing(GO:0000966) germ-line stem cell population maintenance(GO:0030718)
0.1 0.4 GO:0003272 endocardial cushion formation(GO:0003272)
0.1 1.0 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.6 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.4 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 1.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.4 GO:0036372 opsin transport(GO:0036372)
0.1 0.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.3 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.2 GO:2001279 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.2 GO:0036268 swimming(GO:0036268)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.0 0.1 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.2 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.7 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.4 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0033198 response to ATP(GO:0033198)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 0.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.4 GO:0070062 extracellular exosome(GO:0070062)
0.1 3.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.0 1.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 2.1 GO:0043236 laminin binding(GO:0043236)
0.1 0.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 1.2 GO:0070122 isopeptidase activity(GO:0070122)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.3 GO:0034584 piRNA binding(GO:0034584)
0.0 0.8 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.6 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors