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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxa4a+hoxc3a

Z-value: 0.89

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Transcription factors associated with hoxa4a+hoxc3a

Gene Symbol Gene ID Gene Info
ENSDARG00000070339 homeobox C3a
ENSDARG00000103862 homeobox A4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa3adr11_v1_chr19_+_19767567_19767567-0.634.9e-03Click!
hoxc3adr11_v1_chr23_+_36144487_36144487-0.581.1e-02Click!

Activity profile of hoxa4a+hoxc3a motif

Sorted Z-values of hoxa4a+hoxc3a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_40708537 2.70 ENSDART00000077577
si:ch211-132b12.8
chr9_+_44994214 2.55 ENSDART00000141434
retinol saturase (all-trans-retinol 13,14-reductase) like
chr10_-_21362071 2.07 ENSDART00000125167
avidin
chr2_+_6253246 1.96 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr10_-_21362320 1.95 ENSDART00000189789
avidin
chr21_+_25777425 1.90 ENSDART00000021620
claudin d
chr20_-_23426339 1.86 ENSDART00000004625
zygote arrest 1
chr6_+_7414215 1.82 ENSDART00000049339
SRY (sex determining region Y)-box 21a
chr9_-_35633827 1.80 ENSDART00000077745
zona pellucida glycoprotein 2, like 1
chr8_-_23780334 1.79 ENSDART00000145179
ENSDART00000145894
zgc:195245
chr10_+_15255198 1.69 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr10_+_15255012 1.54 ENSDART00000023766
very low density lipoprotein receptor
chr15_+_34592215 1.53 ENSDART00000099776
tetraspanin 13a
chr10_+_44699734 1.51 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scavenger receptor class B, member 1
chr11_-_1550709 1.46 ENSDART00000110097
si:ch73-303b9.1
chr1_-_55248496 1.45 ENSDART00000098615
nanos homolog 3
chr16_-_42056137 1.44 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr10_+_44700103 1.43 ENSDART00000165999
scavenger receptor class B, member 1
chr14_-_33481428 1.42 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lysosomal-associated membrane protein 2
chr23_+_28322986 1.36 ENSDART00000134710
baculoviral IAP repeat containing 5b
chr4_+_11464255 1.31 ENSDART00000008584
GDP dissociation inhibitor 2
chr6_+_28208973 1.29 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
si:ch73-14h10.2
chr12_-_33357655 1.29 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr1_+_55755304 1.23 ENSDART00000144983
trans-2,3-enoyl-CoA reductase b
chr5_-_3927692 1.21 ENSDART00000146840
ENSDART00000058346
complement component 1, q subcomponent binding protein
chr20_+_14114258 1.20 ENSDART00000044937
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr5_-_25733745 1.13 ENSDART00000051566
zgc:101016
chr2_-_15324837 1.04 ENSDART00000015655
trans-2,3-enoyl-CoA reductase-like 2b
chr8_-_38355555 1.03 ENSDART00000134283
ENSDART00000132077
ENSDART00000146378
sorbin and SH3 domain containing 3
chr4_-_73756673 1.01 ENSDART00000174274
ENSDART00000192913
ENSDART00000113546

si:dkey-262g12.14
zgc:171551
chr17_+_16046314 1.00 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr20_-_37813863 0.99 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr17_+_16046132 0.99 ENSDART00000155005
si:ch73-204p21.2
chr20_-_14114078 0.97 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr12_+_22580579 0.95 ENSDART00000171725
ENSDART00000192290
capping protein (actin filament), gelsolin-like b
chr19_-_26923273 0.95 ENSDART00000089609
SKI2 homolog, superkiller viralicidic activity 2-like
chr23_+_29885019 0.91 ENSDART00000167059
aurora kinase A interacting protein 1
chr1_-_13989643 0.90 ENSDART00000191046
E74-like factor 2b (ets domain transcription factor)
chr19_-_4793263 0.90 ENSDART00000147510
ENSDART00000141336
ENSDART00000110551
ENSDART00000146684
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr1_-_513762 0.89 ENSDART00000148162
ENSDART00000144606
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr16_+_24733741 0.89 ENSDART00000155217
si:dkey-79d12.4
chr6_+_21001264 0.89 ENSDART00000044519
ENSDART00000151278
connexin 44.2
chr2_+_8779164 0.85 ENSDART00000134308
zinc finger, ZZ-type containing 3
chr17_+_37227936 0.80 ENSDART00000076009
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
chr23_+_2728095 0.78 ENSDART00000066086
zgc:114123
chr19_+_19976990 0.77 ENSDART00000052627
neuropeptide VF precursor
chr7_+_51774502 0.76 ENSDART00000007767
glutamic-oxaloacetic transaminase 2b, mitochondrial
chr5_+_16117871 0.74 ENSDART00000090657
zinc and ring finger 3
chr25_+_36292057 0.73 ENSDART00000152329
brambleberry
chr20_-_29532939 0.73 ENSDART00000049224
ENSDART00000062377
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr24_-_37640705 0.73 ENSDART00000066583
zgc:112496
chr8_-_38355268 0.70 ENSDART00000129597
sorbin and SH3 domain containing 3
chr11_-_6877973 0.70 ENSDART00000160271
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr1_-_23308225 0.69 ENSDART00000137567
ENSDART00000008201
small integral membrane protein 14
chr12_-_314899 0.68 ENSDART00000066579
6-pyruvoyltetrahydropterin synthase
chr14_+_24935131 0.68 ENSDART00000170871
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr9_+_18829360 0.68 ENSDART00000006514
general transcription factor IIF, polypeptide 2b
chr17_-_40956035 0.67 ENSDART00000124715
si:dkey-16j16.4
chr5_-_30074332 0.67 ENSDART00000147963
beta-carotene oxygenase 2a
chr14_+_22172047 0.66 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr2_+_11205795 0.65 ENSDART00000019078
LIM homeobox 8a
chr7_+_69459759 0.65 ENSDART00000160500
CTD nuclear envelope phosphatase 1b
chr12_+_23912074 0.62 ENSDART00000152864
supervillin a
chr12_-_48188928 0.61 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr21_+_27513859 0.61 ENSDART00000065420
phosphofurin acidic cluster sorting protein 1a
chr9_-_50000144 0.60 ENSDART00000123416
sodium channel, voltage-gated, type I, alpha
chr2_+_10007113 0.59 ENSDART00000155213
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr3_+_1182315 0.58 ENSDART00000055430
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr10_+_15025006 0.57 ENSDART00000145192
ENSDART00000140084
si:dkey-88l16.5
chr22_+_18156000 0.57 ENSDART00000143483
ENSDART00000136133
nuclear receptor 2C2-associated protein
chr21_-_32060993 0.55 ENSDART00000131651
si:ch211-160j14.2
chr21_-_14251306 0.55 ENSDART00000114715
ENSDART00000181380
mannosidase, alpha, class 1B, member 1a
chr19_-_26923957 0.54 ENSDART00000182390
SKI2 homolog, superkiller viralicidic activity 2-like
chr7_-_30174882 0.53 ENSDART00000110409
FERM domain containing 5
chr8_+_25034544 0.53 ENSDART00000123300
neugrin, neurite outgrowth associated
chr2_+_5371492 0.53 ENSDART00000139762
si:ch1073-184j22.1
chr13_-_5252559 0.52 ENSDART00000181652
si:dkey-78p8.1
chr23_-_20051369 0.51 ENSDART00000049836
biglycan b
chr9_-_43644261 0.51 ENSDART00000023684
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr3_+_27798094 0.51 ENSDART00000075100
ENSDART00000151437
calcium regulated heat stable protein 1
chr15_-_46779934 0.51 ENSDART00000085136
chloride channel 2c
chr5_-_41103583 0.51 ENSDART00000051070
ENSDART00000074781
golgi phosphoprotein 3
chr14_-_25935167 0.51 ENSDART00000139855
GTPase activating protein (SH3 domain) binding protein 1
chr20_+_36812368 0.50 ENSDART00000062931
ABRA C-terminal like
chr15_+_32398921 0.50 ENSDART00000156125
ENSDART00000153806
si:ch211-162k9.6
chr15_-_44601331 0.49 ENSDART00000161514
zgc:165508
chr18_+_924949 0.49 ENSDART00000170888
ENSDART00000193163
pyruvate kinase M1/2a
chr6_+_6797520 0.49 ENSDART00000150967
si:ch211-85n16.3
chr6_-_7061086 0.48 ENSDART00000122719
Indian hedgehog homolog b
chr9_-_710896 0.48 ENSDART00000180478
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr10_+_15024772 0.46 ENSDART00000135667
si:dkey-88l16.5
chr17_+_16429826 0.46 ENSDART00000136078
EF-hand calcium binding domain 11
chr19_-_44064842 0.45 ENSDART00000151541
mitochondrial transcription termination factor 3
chr11_+_31609481 0.45 ENSDART00000124830
ENSDART00000162768
zgc:162816
chr5_+_25733774 0.44 ENSDART00000137088
ENSDART00000098467
abhydrolase domain containing 17B
chr25_+_37293312 0.44 ENSDART00000086737
ENSDART00000161595
si:dkey-234i14.9
chr1_+_35985813 0.44 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
chr22_-_26865361 0.44 ENSDART00000182504
heme oxygenase 2a
chr9_+_41080029 0.44 ENSDART00000141179
ENSDART00000019289
zgc:136439
chr2_+_50608099 0.43 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr11_-_18020258 0.43 ENSDART00000156116
glutamine-rich 1
chr24_+_37640626 0.43 ENSDART00000008047
WD repeat domain 24
chr3_+_4502066 0.42 ENSDART00000088610
RAN GTPase activating protein 1a
chr20_-_20270191 0.42 ENSDART00000009356
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr13_+_38814521 0.42 ENSDART00000110976
collagen, type XIX, alpha 1
chr22_+_737211 0.42 ENSDART00000017305
zinc finger protein 76
chr24_-_36238054 0.41 ENSDART00000155725
transmembrane protein 241
chr5_+_36768674 0.41 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr13_+_35856463 0.41 ENSDART00000171056
ENSDART00000017202
potassium channel, subfamily K, member 1b
chr7_+_17106160 0.41 ENSDART00000190048
ENSDART00000180004
ENSDART00000013409
protein arginine methyltransferase 3
chr19_+_7627070 0.41 ENSDART00000151078
ENSDART00000131324
pygopus homolog 2 (Drosophila)
chr2_+_10006839 0.40 ENSDART00000160304
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr7_-_59165640 0.40 ENSDART00000170853
HAUS augmin-like complex, subunit 6
chr5_-_9625459 0.40 ENSDART00000143347
SH2B adaptor protein 3
chr7_+_17973269 0.39 ENSDART00000079969
potassium channel, subfamily K, member 7
chr9_-_27398369 0.38 ENSDART00000186499
testis expressed 30
chr13_+_45431660 0.38 ENSDART00000099950
SYF2 pre-mRNA-splicing factor
chr10_+_13000669 0.38 ENSDART00000158919
ENSDART00000172625
lysophosphatidic acid receptor 1
chr8_+_31717175 0.37 ENSDART00000013434
3-oxoacid CoA transferase 1a
chr9_-_11676491 0.37 ENSDART00000022358
zinc finger CCCH-type containing 15
chr25_-_6292560 0.36 ENSDART00000153496
WD repeat domain 61
chr23_+_2906031 0.36 ENSDART00000109304
c23h20orf24 homolog (H. sapiens)
chr24_+_16547035 0.36 ENSDART00000164319
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr1_+_23311617 0.36 ENSDART00000025770
ENSDART00000139003
ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast)
chr3_-_16719244 0.36 ENSDART00000055859
polymerase (DNA directed), delta 1, catalytic subunit
chr5_+_54497730 0.35 ENSDART00000157722
transmembrane protein 203
chr8_+_18011522 0.35 ENSDART00000136756
single stranded DNA binding protein 3b
chr24_-_25166720 0.34 ENSDART00000141601
pleckstrin homology-like domain, family B, member 2b
chr5_-_1203455 0.34 ENSDART00000172177
surfeit gene 4
chr22_-_20166660 0.34 ENSDART00000085913
ENSDART00000188241
BTB (POZ) domain containing 2a
chr15_-_18115540 0.34 ENSDART00000131639
ENSDART00000047902
archain 1b
chr6_-_48418021 0.34 ENSDART00000090528
ras homolog family member Ca
chr11_-_20096018 0.33 ENSDART00000030420
opioid growth factor receptor-like 2
chr23_-_36446307 0.33 ENSDART00000136623
zgc:174906
chr12_+_1492641 0.32 ENSDART00000152411
ubiquitin specific peptidase 22
chr14_-_26392146 0.32 ENSDART00000037999
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr1_-_23268569 0.32 ENSDART00000143948
replication factor C (activator 1) 1
chr7_+_15308219 0.31 ENSDART00000165683
mesoderm posterior ba
chr3_-_15734358 0.31 ENSDART00000137325
major vault protein
chr8_-_11988065 0.31 ENSDART00000005140
mediator complex subunit 27
chr9_-_3934963 0.31 ENSDART00000062336
ubiquitin protein ligase E3 component n-recognin 3
chr6_-_55399214 0.31 ENSDART00000168367
cathepsin A
chr1_-_51710225 0.30 ENSDART00000057601
ENSDART00000152745
small nuclear ribonucleoprotein polypeptide B2
chr19_+_5480327 0.30 ENSDART00000148794
junction plakoglobin b
chr19_+_41464870 0.29 ENSDART00000102778
distal-less homeobox 6a
chr13_-_9213207 0.29 ENSDART00000139861
ENSDART00000140524
si:dkey-33c12.11
chr4_+_25917915 0.29 ENSDART00000138603
vezatin, adherens junctions transmembrane protein
chr23_-_31060350 0.29 ENSDART00000145598
ENSDART00000191491
si:ch211-197l9.5
chr3_-_15734530 0.29 ENSDART00000141142
major vault protein
chr16_+_4654333 0.28 ENSDART00000167665
si:ch1073-284b18.2
chr11_-_15296805 0.28 ENSDART00000124968
ribophorin II
chr13_+_4225173 0.27 ENSDART00000058242
ENSDART00000143456
male-enhanced antigen 1
chr14_+_30795559 0.27 ENSDART00000006132
cofilin 1
chr7_+_69019851 0.26 ENSDART00000162891

chr21_+_15592426 0.26 ENSDART00000138207
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr18_+_14619544 0.26 ENSDART00000010821
UTP4, small subunit processome component
chr3_+_17537352 0.25 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr24_+_40860320 0.25 ENSDART00000161351
golgi reassembly stacking protein 1b
chr19_+_40115977 0.25 ENSDART00000139802
si:ch211-173p18.3
chr17_-_37395460 0.25 ENSDART00000148160
ENSDART00000075975
cysteine-rich protein 1
chr13_-_9045879 0.25 ENSDART00000155463
ENSDART00000140041
ENSDART00000137454
si:dkey-112g5.11
chr21_-_37075542 0.24 ENSDART00000129439

chr22_-_38621438 0.24 ENSDART00000098330
natriuretic peptide C
chr5_+_1624359 0.24 ENSDART00000165431
protein phosphatase 1 catalytic subunit gamma
chr10_-_25561751 0.24 ENSDART00000147089
glutamate receptor, ionotropic, kainate 1a
chr6_+_23026714 0.24 ENSDART00000124948
signal recognition particle 68
chr12_-_19119176 0.24 ENSDART00000149180
aconitase 2, mitochondrial
chr4_+_13586689 0.23 ENSDART00000067161
ENSDART00000138201
transportin 3
chr9_+_29643036 0.23 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr14_-_26392475 0.22 ENSDART00000170614
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr21_-_37435162 0.22 ENSDART00000133585
family with sequence similarity 114, member A2
chr16_+_42471455 0.22 ENSDART00000166640
si:ch211-215k15.5
chr20_-_28800999 0.22 ENSDART00000049462
RAB15, member RAS oncogene family
chr14_+_21820034 0.22 ENSDART00000122739
C-terminal binding protein 1
chr3_-_402714 0.22 ENSDART00000134062
ENSDART00000105659
major histocompatibility complex class I ZJA
chr13_-_9111927 0.22 ENSDART00000133815
ENSDART00000109783
ENSDART00000142540
ENSDART00000192613
si:dkey-19p15.4
si:dkey-112g5.12
chr7_+_22313533 0.22 ENSDART00000123457
si:dkey-11f12.2
chr8_-_23776399 0.21 ENSDART00000114800
si:ch211-163l21.4
chr9_-_43538328 0.21 ENSDART00000140526
zinc finger protein 385B
chr10_+_16036246 0.21 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lamin B1
chr13_-_35808904 0.21 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr22_-_36530902 0.21 ENSDART00000056188
info polymerase (RNA) II (DNA directed) polypeptide H
chr2_-_26596794 0.20 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr5_+_40485503 0.20 ENSDART00000051055
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr18_+_39487486 0.20 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr9_-_44897553 0.20 ENSDART00000110697
DnaJ (Hsp40) homolog, subfamily C, member 10
chr10_-_15963903 0.20 ENSDART00000142357
si:dkey-3h23.3
chr15_-_17618800 0.20 ENSDART00000157185
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr2_+_36828746 0.20 ENSDART00000186638
nardilysin a (N-arginine dibasic convertase)
chr6_-_12275836 0.19 ENSDART00000189980
plakophilin 4
chr23_-_2901167 0.19 ENSDART00000165955
ENSDART00000190616
zinc fingers and homeoboxes 3
chr7_+_36898850 0.19 ENSDART00000113342
TOX high mobility group box family member 3
chr4_-_9664995 0.19 ENSDART00000180105
ENSDART00000029084
cyclin D binding myb-like transcription factor 1
chr10_+_34175476 0.19 ENSDART00000102123
zgc:174193
chr13_+_9468535 0.18 ENSDART00000135088
ENSDART00000164270
ENSDART00000099619
ENSDART00000164656
si:dkey-265c15.6
chr3_-_53722182 0.18 ENSDART00000032788
retinol dehydrogenase 8a
chr25_+_13620555 0.18 ENSDART00000163642
si:ch211-172l8.4
chr8_+_3434146 0.18 ENSDART00000164426
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr3_+_22035863 0.18 ENSDART00000177169
cell division cycle 27
chr20_+_50184934 0.18 ENSDART00000158388
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa4a+hoxc3a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.5 1.4 GO:0000212 meiotic spindle organization(GO:0000212)
0.4 1.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 1.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 1.2 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.2 3.4 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.8 GO:0045938 regulation of endocrine process(GO:0044060) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) endocrine hormone secretion(GO:0060986)
0.2 0.8 GO:0006531 aspartate metabolic process(GO:0006531)
0.2 0.7 GO:0032801 receptor catabolic process(GO:0032801)
0.2 0.9 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.7 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.1 0.7 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 1.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 1.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.3 GO:0022410 circadian sleep/wake cycle process(GO:0022410) circadian sleep/wake cycle(GO:0042745)
0.1 0.5 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.1 0.5 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.8 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.5 GO:0046416 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.1 0.5 GO:0006788 heme oxidation(GO:0006788)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.3 GO:0051645 Golgi localization(GO:0051645)
0.1 0.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.5 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.7 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.4 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.3 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 2.3 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.7 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 1.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.6 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 3.0 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.4 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.8 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.5 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.1 GO:0043092 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.0 1.9 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 1.9 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.5 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.3 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 0.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.7 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.5 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.4 1.8 GO:0055087 Ski complex(GO:0055087)
0.2 0.7 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 3.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.1 0.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.6 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.4 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 0.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 2.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:0035060 brahma complex(GO:0035060)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 1.0 GO:0001726 ruffle(GO:0001726)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.0 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.8 4.0 GO:0009374 biotin binding(GO:0009374)
0.7 2.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.4 1.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.3 0.8 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 0.7 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 0.9 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.2 3.4 GO:0032190 acrosin binding(GO:0032190)
0.2 0.8 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 1.2 GO:0008494 translation activator activity(GO:0008494)
0.1 0.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 1.0 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.7 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 0.5 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.0 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.4 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism