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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxa10b

Z-value: 0.69

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Transcription factors associated with hoxa10b

Gene Symbol Gene ID Gene Info
ENSDARG00000031337 homeobox A10b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa10bdr11_v1_chr16_+_20910186_20910186-0.361.4e-01Click!

Activity profile of hoxa10b motif

Sorted Z-values of hoxa10b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_25887864 1.95 ENSDART00000152983
si:dkey-193p11.2
chr1_-_9485939 1.70 ENSDART00000157814
mical-like 2b
chr11_-_25257045 1.63 ENSDART00000130477
snail family zinc finger 1a
chr7_+_1473929 1.57 ENSDART00000050687
lysophosphatidylcholine acyltransferase 4
chr24_-_21090447 1.35 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
queuine tRNA-ribosyltransferase accessory subunit 2
chr2_-_17115256 1.32 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr13_-_24717618 1.28 ENSDART00000172156
ER lipid raft associated 1
chr17_+_50701748 1.23 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermitin family member 2
chr13_-_24717365 1.18 ENSDART00000137934
ENSDART00000003922
ER lipid raft associated 1
chr2_+_51818039 1.18 ENSDART00000170353
activin A receptor type 2Bb
chr14_+_45028062 1.16 ENSDART00000184717
ENSDART00000185481
ATPase phospholipid transporting 8A1
chr10_+_15340768 1.15 ENSDART00000046274
ENSDART00000168909
trafficking protein particle complex 13
chr22_-_881725 1.12 ENSDART00000035514
choline/ethanolamine phosphotransferase 1b
chr12_-_4243268 0.99 ENSDART00000131275
zgc:92313
chr11_+_11303458 0.98 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
chr12_-_18961289 0.95 ENSDART00000168405
E1A binding protein p300 a
chr14_-_16082806 0.95 ENSDART00000165656
MAX dimerization protein 3
chr15_-_43978141 0.94 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr21_-_14878220 0.92 ENSDART00000131237
unc-51 like autophagy activating kinase 1
chr3_+_39579393 0.87 ENSDART00000055170
ceroid-lipofuscinosis, neuronal 3
chr19_-_47571456 0.86 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr16_-_44945224 0.85 ENSDART00000156921
neural cell adhesion molecule 3
chr2_+_22409249 0.85 ENSDART00000182915
zgc:56628
chr12_-_10512911 0.85 ENSDART00000124562
ENSDART00000106163
zgc:152977
chr6_-_7107868 0.84 ENSDART00000171123
nonhomologous end-joining factor 1
chr22_-_20950448 0.84 ENSDART00000002029
FK506 binding protein 8
chr22_+_15959844 0.81 ENSDART00000182201
scl/tal1 interrupting locus
chr10_-_31805923 0.81 ENSDART00000077785
vacuolar protein sorting 26 homolog B, like
chr13_+_8892784 0.80 ENSDART00000075054
ENSDART00000143705
thyroid adenoma associated
chr17_-_30652738 0.79 ENSDART00000154960
SH3 and SYLF domain containing 1
chr21_+_43178831 0.78 ENSDART00000151512
AF4/FMR2 family, member 4
chr14_+_22132388 0.77 ENSDART00000109065
cyclin G1
chr11_-_25257595 0.76 ENSDART00000123567
snail family zinc finger 1a
chr12_-_18961491 0.75 ENSDART00000172574
E1A binding protein p300 a
chr13_-_17860307 0.75 ENSDART00000135920
ENSDART00000054579
membrane-associated ring finger (C3HC4) 8
chr8_+_2656231 0.74 ENSDART00000160833
family with sequence similarity 102, member Aa
chr25_+_3549841 0.73 ENSDART00000164030
coiled-coil domain containing 77
chr20_-_29499363 0.73 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
ribonucleotide reductase M2 polypeptide
chr5_-_65121747 0.71 ENSDART00000165556
torsin family 2, member A
chr15_+_22390076 0.71 ENSDART00000183764
OAF homolog a (Drosophila)
chr15_-_1843831 0.70 ENSDART00000156718
ENSDART00000154175
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr14_-_50028428 0.69 ENSDART00000163543
ENSDART00000168510
abhydrolase domain containing 18
chr1_-_14506759 0.69 ENSDART00000057044
si:dkey-194g4.1
chr13_+_7575563 0.68 ENSDART00000146592
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr8_-_18899427 0.68 ENSDART00000079840
RAR-related orphan receptor C a
chr6_-_9282080 0.68 ENSDART00000159506
coiled-coil domain containing 14
chr2_-_10877765 0.67 ENSDART00000100607
cell division cycle 7 homolog (S. cerevisiae)
chr13_+_33462232 0.67 ENSDART00000177841
zgc:136302
chr19_-_47571797 0.66 ENSDART00000166180
ENSDART00000168134
ribonucleotide reductase M2 polypeptide
chr12_+_19199735 0.65 ENSDART00000066393
pdgfa associated protein 1a
chr16_+_35916371 0.65 ENSDART00000167208
SH3 domain containing 21
chr8_-_11324143 0.65 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr12_-_11560794 0.65 ENSDART00000149098
ENSDART00000169975
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b
chr23_-_29751730 0.64 ENSDART00000056865
catenin, beta interacting protein 1
chr9_-_36924388 0.63 ENSDART00000059756
v-ral simian leukemia viral oncogene homolog Ba (ras related)
chr13_+_9559461 0.63 ENSDART00000047740
WD repeat domain 32
chr18_-_39288894 0.63 ENSDART00000186216
mitogen-activated protein kinase 6
chr8_+_35964482 0.63 ENSDART00000129357
ENSDART00000154953
glycosyltransferase 1 domain containing 1
chr21_-_14830353 0.62 ENSDART00000134687
pseudouridylate synthase 1
chr22_-_12337781 0.62 ENSDART00000188357
ENSDART00000123574
zinc finger, RAN-binding domain containing 3
chr22_+_23430688 0.61 ENSDART00000160457
DENN/MADD domain containing 1B
chr2_-_40890004 0.61 ENSDART00000191746
UDP-glucose glycoprotein glucosyltransferase 1
chr15_-_1844048 0.60 ENSDART00000102410
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr12_+_33361948 0.60 ENSDART00000124982
fatty acid synthase
chr2_-_40889465 0.60 ENSDART00000192631
ENSDART00000180824
UDP-glucose glycoprotein glucosyltransferase 1
chr2_+_49805892 0.60 ENSDART00000056248
WD repeat domain 48b
chr19_+_27970292 0.60 ENSDART00000103887
ENSDART00000145549
mediator complex subunit 10
chr2_-_37458527 0.59 ENSDART00000146820
si:dkey-57k2.7
chr22_+_5574952 0.59 ENSDART00000171774
zgc:171566
chr1_+_45663727 0.59 ENSDART00000038574
ENSDART00000141144
ENSDART00000149565
trafficking protein particle complex 5
chr1_+_12394205 0.58 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
chr1_+_2321384 0.58 ENSDART00000157662
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr12_+_3262564 0.56 ENSDART00000184264
transmembrane protein 101
chr15_-_5901514 0.56 ENSDART00000155252
si:ch73-281n10.2
chr12_-_20409794 0.55 ENSDART00000077936
leucine carboxyl methyltransferase 1
chr23_+_45200481 0.55 ENSDART00000004357
ENSDART00000111126
ENSDART00000193560
ENSDART00000190476
PC4 and SFRS1 interacting protein 1b
chr19_+_7424347 0.54 ENSDART00000004622
splicing factor 3b, subunit 4
chr14_+_22467672 0.54 ENSDART00000079409
ENSDART00000136597
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr20_-_34670236 0.54 ENSDART00000033325
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_-_60589292 0.53 ENSDART00000157822
jumonji domain containing 6
chr7_-_30280934 0.53 ENSDART00000126741
small EDRK-rich factor 2
chr13_-_25745089 0.52 ENSDART00000189333
ENSDART00000147420
sphingosine-1-phosphate lyase 1
chr13_+_13945218 0.52 ENSDART00000089501
ENSDART00000142997
eukaryotic translation initiation factor 2-alpha kinase 3
chr21_-_11970199 0.52 ENSDART00000114524
NOP56 ribonucleoprotein homolog
chr22_+_1953096 0.51 ENSDART00000166630
ENSDART00000186234
si:dkey-15h8.16
chr8_-_31416403 0.51 ENSDART00000098912
zinc finger protein 131
chr23_-_24253200 0.51 ENSDART00000114840
zinc finger and BTB domain containing 17
chr12_+_13205955 0.51 ENSDART00000092906
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr18_+_15876385 0.51 ENSDART00000142527
early endosome antigen 1
chr6_+_40554551 0.50 ENSDART00000017859
ENSDART00000155928
DNA-damage inducible protein 2
chr16_-_32671998 0.50 ENSDART00000161395
PNN-interacting serine/arginine-rich protein
chr20_+_26943072 0.49 ENSDART00000153215
cell division cycle associated 4
chr20_-_23219964 0.49 ENSDART00000144933
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr7_+_17907883 0.49 ENSDART00000147564
metastasis associated 1 family, member 2
chr16_+_46401756 0.48 ENSDART00000147370
ENSDART00000144000
rapunzel 2
chr3_-_4501026 0.48 ENSDART00000163052
zgc:162198
chr2_-_50272077 0.47 ENSDART00000127623
cullin 1a
chr11_-_25461336 0.47 ENSDART00000014945
host cell factor C1a
chr23_+_20431140 0.47 ENSDART00000193950
solute carrier family 35 (GDP-fucose transporter), member C2
chr15_-_26931541 0.47 ENSDART00000027563
coiled-coil domain containing 9
chr2_+_49457449 0.46 ENSDART00000185470
SH3-domain GRB2-like 1a
chr2_-_49627099 0.46 ENSDART00000083710
ENSDART00000147421
cactin
chr13_+_33268657 0.46 ENSDART00000002095
transmembrane protein 39B
chr10_-_20588787 0.45 ENSDART00000138045
ENSDART00000181885
ENSDART00000091115
nuclear receptor binding SET domain protein 3
chr21_+_43702016 0.44 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr13_+_15580758 0.43 ENSDART00000087194
ENSDART00000013525
MAP/microtubule affinity-regulating kinase 3a
chr22_+_30195257 0.42 ENSDART00000027803
ENSDART00000172496
adducin 3 (gamma) a
chr25_+_3549401 0.42 ENSDART00000166312
coiled-coil domain containing 77
chr3_-_45778123 0.41 ENSDART00000146211
H3 histone, family 3B.1
chr17_+_17764979 0.40 ENSDART00000105013
alkB homolog 1, histone H2A dioxygenase
chr24_-_3407507 0.40 ENSDART00000132648
NCK adaptor protein 1b
chr25_-_29074064 0.40 ENSDART00000165603
AT rich interactive domain 3B (BRIGHT-like)
chr5_-_68074592 0.40 ENSDART00000165052
ENSDART00000018792
sperm associated antigen 7
chr14_-_238931 0.39 ENSDART00000161122
biorientation of chromosomes in cell division 1-like 1
chr20_-_36416922 0.39 ENSDART00000019145
lamin B receptor
chr19_-_30447611 0.39 ENSDART00000073705
ENSDART00000048977
ENSDART00000191237
ATP-binding cassette, sub-family F (GCN20), member 1
chr14_-_47963115 0.38 ENSDART00000003826
Rap guanine nucleotide exchange factor (GEF) 2
chr7_-_8712148 0.38 ENSDART00000065488
testis expressed 261
chr1_+_41596099 0.38 ENSDART00000111367
si:dkey-56e3.3
chr16_-_32671782 0.38 ENSDART00000123980
PNN-interacting serine/arginine-rich protein
chr13_+_1131748 0.37 ENSDART00000054318
WD repeat domain 92
chr7_-_7692992 0.36 ENSDART00000192619
aminoadipate aminotransferase
chr17_+_15535501 0.36 ENSDART00000002932
myristoylated alanine-rich protein kinase C substrate b
chr6_-_10728921 0.36 ENSDART00000151484
Sp3b transcription factor
chr9_+_30090656 0.36 ENSDART00000102981
collagen, type VIII, alpha 1a
chr7_-_7692723 0.35 ENSDART00000183352
aminoadipate aminotransferase
chr24_-_15159658 0.35 ENSDART00000142473
rotatin
chr20_-_34801181 0.35 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr17_-_25630822 0.35 ENSDART00000126201
ENSDART00000105503
ENSDART00000151878
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr10_+_6013076 0.34 ENSDART00000167613
ENSDART00000159216
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr3_+_31093455 0.34 ENSDART00000153074
si:dkey-66i24.9
chr22_+_1947494 0.34 ENSDART00000159121
si:dkey-15h8.15
chr5_-_57289872 0.34 ENSDART00000189893
ENSDART00000050957
fer (fps/fes related) tyrosine kinase
chr20_-_45709990 0.33 ENSDART00000027482
glycerophosphocholine phosphodiesterase 1
chr14_+_26439227 0.33 ENSDART00000054183
G protein-coupled receptor 137
chr12_-_33817114 0.32 ENSDART00000161265
twinkle mtDNA helicase
chr12_+_27285994 0.32 ENSDART00000087204
dual specificity phosphatase 3a
chr24_-_23784701 0.32 ENSDART00000090368
serum/glucocorticoid regulated kinase family, member 3
chr1_-_41374117 0.32 ENSDART00000074777
huntingtin
chr6_-_30485009 0.31 ENSDART00000025698
zgc:153311
chr4_-_11053543 0.31 ENSDART00000067262
methyltransferase like 25
chr5_+_20453874 0.31 ENSDART00000124545
ENSDART00000008402
squamous cell carcinoma antigen recognized by T cells 3
chr4_-_17353972 0.31 ENSDART00000041529
PARP1 binding protein
chr2_+_21048661 0.30 ENSDART00000156876
ras responsive element binding protein 1b
chr5_+_27137473 0.30 ENSDART00000181833
unc-5 netrin receptor Db
chr13_+_29292011 0.30 ENSDART00000115023
poly (ADP-ribose) glycohydrolase a
chr25_+_9013342 0.29 ENSDART00000154207
ENSDART00000153705
im:7145024
chr15_-_20731638 0.29 ENSDART00000170616
tyrosylprotein sulfotransferase 1
chr23_-_29505645 0.29 ENSDART00000146458
kinesin family member 1B
chr10_-_33297864 0.29 ENSDART00000163360
PR/SET domain 15
chr3_+_60589157 0.29 ENSDART00000165367
methyltransferase like 23
chr18_+_6857071 0.29 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr14_+_45608576 0.29 ENSDART00000173248
si:ch211-276i12.11
chr1_+_27808916 0.28 ENSDART00000102335
paraspeckle component 1
chr20_-_25709247 0.28 ENSDART00000146711
si:dkeyp-117h8.2
chr21_-_26691959 0.28 ENSDART00000149702
ENSDART00000149840
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr25_+_20089986 0.28 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr15_-_47857687 0.27 ENSDART00000098982
ENSDART00000151594
H3 histone, family 3B.1
chr5_+_37032038 0.27 ENSDART00000045036
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr11_-_26362294 0.27 ENSDART00000184654
ENSDART00000115037
forkhead box J3
chr9_-_40765868 0.27 ENSDART00000138634
ATP-binding cassette, sub-family A (ABC1), member 12
chr4_+_23125689 0.26 ENSDART00000077854
MDM2 oncogene, E3 ubiquitin protein ligase
chr20_+_32552912 0.26 ENSDART00000009691
Scm polycomb group protein like 4
chr6_+_45692026 0.26 ENSDART00000164759
contactin 4
chr24_+_10202718 0.26 ENSDART00000126668
POU class 6 homeobox 2
chr5_-_37881345 0.26 ENSDART00000084819
Rho GTPase activating protein 35b
chr2_+_54086436 0.26 ENSDART00000174581

chr16_+_52966812 0.25 ENSDART00000148435
ENSDART00000049099
ENSDART00000150117
thyroid hormone receptor interactor 13
chr17_+_43595692 0.25 ENSDART00000156271
cilia and flagella associated protein 99
chr16_+_54829293 0.25 ENSDART00000024729
poly(A) binding protein, cytoplasmic 1a
chr12_+_23912074 0.25 ENSDART00000152864
supervillin a
chr25_+_28823952 0.24 ENSDART00000067072
nuclear transcription factor Y, beta b
chr1_+_52392511 0.24 ENSDART00000144025
si:ch211-217k17.8
chr15_-_46718759 0.24 ENSDART00000085926
ENSDART00000154577
zgc:162872
chr11_+_31730680 0.24 ENSDART00000145497
diaphanous-related formin 3
chr2_+_25315591 0.24 ENSDART00000161386
fibronectin type III domain containing 3Ba
chr6_+_8315050 0.24 ENSDART00000189987
glutaryl-CoA dehydrogenase a
chr16_-_52966811 0.23 ENSDART00000153758
ENSDART00000009256
bromodomain containing 9
chr14_+_10625112 0.23 ENSDART00000143377
ENSDART00000136480
nucleoporin 62 like
chr25_-_14433503 0.23 ENSDART00000103957
exocyst complex component 3-like 1
chr22_+_10606573 0.22 ENSDART00000192638
RAD54 like 2
chr25_+_22571475 0.22 ENSDART00000161559
stimulated by retinoic acid 6
chr8_-_10947205 0.22 ENSDART00000164467
PQ loop repeat containing 2
chr24_+_14581864 0.22 ENSDART00000134536
thiamine triphosphatase
chr1_-_55873178 0.22 ENSDART00000019936
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
chr23_-_21215311 0.22 ENSDART00000112424
multiple EGF-like-domains 6a
chr8_+_3820134 0.22 ENSDART00000122454
citron rho-interacting serine/threonine kinase b
chr19_+_40069524 0.21 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr12_+_32368574 0.21 ENSDART00000086389
si:ch211-277e21.2
chr4_-_22749553 0.20 ENSDART00000040033
nucleoporin 107
chr2_+_19163965 0.19 ENSDART00000166073
ELOVL fatty acid elongase 1a
chr12_-_10476448 0.19 ENSDART00000106172
Rac family small GTPase 1a
chr13_+_4888351 0.19 ENSDART00000145940
mitochondrial calcium uptake 1
chr18_+_21951551 0.19 ENSDART00000146261
RAN binding protein 10
chr3_-_5277041 0.19 ENSDART00000046995
thioredoxin 2
chr23_-_21215520 0.19 ENSDART00000143206
multiple EGF-like-domains 6a
chr2_+_35733335 0.19 ENSDART00000113489
RAS protein activator like 2
chr5_+_50913034 0.18 ENSDART00000149787
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr2_+_20967673 0.18 ENSDART00000057174
actin related protein 2/3 complex, subunit 5A
chr15_+_29727799 0.18 ENSDART00000182006
zgc:153372

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa10b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 1.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 2.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 0.6 GO:1905072 cardiac jelly development(GO:1905072)
0.2 2.5 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 0.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 0.5 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.6 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.9 GO:0015809 arginine transport(GO:0015809)
0.1 0.3 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 2.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.3 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.1 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.6 GO:0048478 replication fork protection(GO:0048478)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.4 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.1 1.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.2 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.3 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.6 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 0.2 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.1 GO:1902626 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.0 1.2 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.2 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.3 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.4 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.8 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.3 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.5 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 1.7 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0014028 notochord formation(GO:0014028)
0.0 0.5 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 0.2 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.8 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.9 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.2 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.0 0.9 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.6 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.4 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.4 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.0 GO:0071241 cellular response to inorganic substance(GO:0071241)
0.0 0.1 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.1 GO:0006400 tRNA modification(GO:0006400)
0.0 0.5 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.2 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.1 GO:0090594 nitric oxide mediated signal transduction(GO:0007263) regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284) inflammatory response to wounding(GO:0090594)
0.0 0.3 GO:0007340 acrosome reaction(GO:0007340)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.2 1.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 0.8 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.8 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.8 GO:0030904 retromer complex(GO:0030904)
0.0 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.9 GO:0005657 replication fork(GO:0005657)
0.0 1.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 1.7 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.5 GO:0016607 nuclear speck(GO:0016607)
0.0 1.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 2.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 1.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 1.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2 1.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.2 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.7 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.4 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 0.3 GO:2001070 starch binding(GO:2001070)
0.1 0.3 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 1.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.9 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.2 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 0.2 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 3.1 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 0.2 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 1.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.3 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 1.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID P73PATHWAY p73 transcription factor network
0.0 0.3 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)