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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hmbox1a+zgc:91944

Z-value: 0.40

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Transcription factors associated with hmbox1a+zgc:91944

Gene Symbol Gene ID Gene Info
ENSDARG00000027082 homeobox containing 1a
ENSDARG00000035887 91944
ENSDARG00000109287 homeobox containing 1 b
ENSDARG00000114642 91944

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hmbox1adr11_v1_chr17_-_16324565_163245650.841.6e-05Click!
CABZ01078261.1dr11_v1_chr20_+_49787584_497875840.753.4e-04Click!
zgc:91944dr11_v1_chr19_-_32600823_32600868-0.302.3e-01Click!

Activity profile of hmbox1a+zgc:91944 motif

Sorted Z-values of hmbox1a+zgc:91944 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_35191220 0.63 ENSDART00000110552
zinc finger, DHHC-type containing 1
chr18_+_35130416 0.59 ENSDART00000151595
si:ch211-195m9.3
chr2_-_21438492 0.54 ENSDART00000046098
phospholipase C, delta 1b
chr10_+_7709724 0.52 ENSDART00000097670
gamma-glutamyl carboxylase
chr17_+_21902058 0.52 ENSDART00000142178
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a
chr13_-_21672131 0.46 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr2_-_27619954 0.45 ENSDART00000144826
trimethylguanosine synthase 1
chr7_+_36467796 0.43 ENSDART00000146202
akt interacting protein
chr15_-_1036878 0.41 ENSDART00000123844
si:dkey-77f5.3
chr17_-_11368662 0.38 ENSDART00000159061
ENSDART00000188694
ENSDART00000190932
si:ch211-185a18.2
chr15_+_6459847 0.37 ENSDART00000157250
ENSDART00000065824
beta-site APP-cleaving enzyme 2
chr19_-_20430892 0.37 ENSDART00000111409
TBC1 domain family, member 5
chr13_+_39182099 0.36 ENSDART00000131434
family with sequence similarity 135, member A
chr19_+_43669122 0.35 ENSDART00000139151
si:ch211-193k19.1
chr23_+_25868637 0.35 ENSDART00000103934
tocopherol (alpha) transfer protein-like
chr3_-_23512285 0.34 ENSDART00000159151

chr23_-_36857964 0.34 ENSDART00000188822
ENSDART00000134061
ENSDART00000093061
homeodomain interacting protein kinase 1a
chr5_-_11809404 0.33 ENSDART00000132564
neurofibromin 2a (merlin)
chr4_+_26056548 0.33 ENSDART00000171204
si:ch211-244b2.1
chr12_-_13650344 0.32 ENSDART00000124364
ENSDART00000124638
ENSDART00000171929
signal transducer and activator of transcription 5b
chr17_-_15188440 0.31 ENSDART00000151885
WD repeat and HMG-box DNA binding protein 1
chr10_-_26196383 0.31 ENSDART00000192925
FH2 domain containing 3
chr16_-_42965192 0.31 ENSDART00000113714
metaxin 1a
chr7_-_25133783 0.31 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
BCL2 associated agonist of cell death b
chr3_-_26806032 0.30 ENSDART00000143710
phosphatidylinositol glycan anchor biosynthesis, class Q
chr2_+_23701613 0.30 ENSDART00000047073
oxidative stress responsive 1a
chr12_+_19281189 0.30 ENSDART00000153428
trinucleotide repeat containing 6b
chr13_-_36050303 0.29 ENSDART00000134955
ENSDART00000139087
legumain
chr12_+_10706772 0.29 ENSDART00000158227
DNA topoisomerase II alpha
chr6_+_44197348 0.29 ENSDART00000075486
protein phosphatase 4, regulatory subunit 2b
chr11_+_25129013 0.29 ENSDART00000132879
ndrg family member 3a
chr22_-_1079773 0.29 ENSDART00000136668
si:ch1073-15f12.3
chr19_-_20099394 0.28 ENSDART00000126173
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr10_-_26202766 0.28 ENSDART00000136393
FH2 domain containing 3
chr1_-_23596391 0.28 ENSDART00000155184
ligand dependent nuclear receptor corepressor-like
chr18_-_20458840 0.27 ENSDART00000177125
kinesin family member 23
chrM_+_6425 0.27 ENSDART00000093606
cytochrome c oxidase I, mitochondrial
chr21_-_36453417 0.27 ENSDART00000018350
CCR4-NOT transcription complex, subunit 8
chr12_-_26538823 0.27 ENSDART00000143213
acyl-CoA synthetase family member 2
chr9_-_54248182 0.26 ENSDART00000129540
leucyl-tRNA synthetase a
chr9_-_9228941 0.26 ENSDART00000121665
cystathionine-beta-synthase b
chr10_-_44008241 0.26 ENSDART00000137686
acyl-CoA dehydrogenase short chain
chr20_-_33512275 0.26 ENSDART00000185959
papilin b, proteoglycan-like sulfated glycoprotein
chr2_+_23677179 0.26 ENSDART00000153918
oxidative stress responsive 1a
chr3_-_47128096 0.25 ENSDART00000063287
queuine tRNA-ribosyltransferase 1
chr6_+_13506841 0.25 ENSDART00000032331
GDP-mannose pyrophosphorylase Ab
chr10_+_16036246 0.25 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lamin B1
chr21_+_37090585 0.24 ENSDART00000182971
zinc finger protein 346
chr16_-_17699111 0.24 ENSDART00000108581
si:dkey-17m8.1
chr23_+_13528053 0.24 ENSDART00000162217
uridine-cytidine kinase 1-like 1b
chr10_+_41939963 0.24 ENSDART00000126248
transmembrane protein 120B
chr9_+_29431763 0.23 ENSDART00000186095
ENSDART00000182640
UDP-glucose glycoprotein glucosyltransferase 2
chr24_-_7587401 0.23 ENSDART00000093163
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr16_+_33992418 0.23 ENSDART00000101885
ENSDART00000130540
zinc finger, DHHC-type containing 18a
chr16_+_33121106 0.22 ENSDART00000110195
akirin 1
chr1_-_11104805 0.22 ENSDART00000147648
kinetochore scaffold 1
chr3_+_30922947 0.22 ENSDART00000184060
claudin i
chr20_-_34670236 0.22 ENSDART00000033325
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr4_+_2059692 0.22 ENSDART00000067427
YEATS domain containing 4
chr11_+_42474694 0.21 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
chr5_-_15283509 0.21 ENSDART00000052712
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr10_-_22912255 0.21 ENSDART00000131992
si:ch1073-143l10.2
chr11_+_25157374 0.20 ENSDART00000019450
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr18_+_13077800 0.20 ENSDART00000161153
gigaxonin
chr13_+_28785814 0.20 ENSDART00000039028
NSE4 homolog A, SMC5-SMC6 complex component
chr12_-_18577774 0.20 ENSDART00000078166
zinc finger, DHHC-type containing 4
chr25_+_28825657 0.20 ENSDART00000153625
nuclear transcription factor Y, beta b
chr1_+_513986 0.20 ENSDART00000109083
ENSDART00000081945
thioredoxin-like 4B
chr3_+_13842554 0.20 ENSDART00000162317
ENSDART00000158068
interleukin enhancer binding factor 3b
chr22_-_36770649 0.20 ENSDART00000169442
aminoacylase 1
chr13_+_46718518 0.20 ENSDART00000160401
ENSDART00000182884
transmembrane protein 63Ba
chr12_-_49151326 0.19 ENSDART00000153244
BUB3 mitotic checkpoint protein
chr10_+_45302425 0.19 ENSDART00000159954
zinc finger, MIZ-type containing 2
chr13_+_8840772 0.19 ENSDART00000059321
epithelial cell adhesion molecule
chr7_+_13609457 0.19 ENSDART00000172857
ankyrin repeat and death domain containing 1A
chr24_+_28953089 0.19 ENSDART00000153761
RNA-binding region (RNP1, RRM) containing 3
chr3_+_22335030 0.19 ENSDART00000055676
zgc:103564
chr12_-_27588299 0.19 ENSDART00000178023
ENSDART00000066282
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr11_-_6868287 0.19 ENSDART00000037824
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr13_-_24906307 0.19 ENSDART00000148191
ENSDART00000189810
K(lysine) acetyltransferase 6B
chr18_-_31051847 0.19 ENSDART00000170982
growth arrest-specific 8
chr7_+_17938128 0.18 ENSDART00000141044
metastasis associated 1 family, member 2
chr25_-_25736958 0.18 ENSDART00000166308
calcium and integrin binding family member 2
chr17_+_30591287 0.18 ENSDART00000154243
si:dkey-190l8.2
chr5_+_20257225 0.18 ENSDART00000127919
slingshot protein phosphatase 1a
chr12_-_999762 0.18 ENSDART00000127003
ENSDART00000084076
ENSDART00000152425
methyltransferase like 9
chr16_+_29690708 0.17 ENSDART00000103054
LysM, putative peptidoglycan-binding, domain containing 1
chr6_-_40657653 0.17 ENSDART00000154359
peptidylprolyl isomerase (cyclophilin)-like 1
chr9_-_25328527 0.17 ENSDART00000060840
mediator complex subunit 4
chr13_+_48359573 0.17 ENSDART00000161959
ENSDART00000165311
mutS homolog 6 (E. coli)
chr22_+_28818291 0.17 ENSDART00000136032
tumor protein p53 binding protein, 2b
chr7_-_38570878 0.17 ENSDART00000139187
ENSDART00000134570
ENSDART00000041055
cugbp, Elav-like family member 1
chr25_-_19486399 0.17 ENSDART00000155076
ENSDART00000156016
zgc:193812
chr15_+_19335646 0.16 ENSDART00000062569
acyl-CoA dehydrogenase family, member 8
chr12_+_3723650 0.16 ENSDART00000179922
ENSDART00000152482
ENSDART00000108771
PAXIP1 associated glutamate-rich protein 1
chr19_+_7559901 0.16 ENSDART00000141189
pre-B-cell leukemia homeobox interacting protein 1a
chr21_-_2042037 0.16 ENSDART00000171131
ENSDART00000160144
adducin 1 (alpha)
chr2_-_32366287 0.16 ENSDART00000144758
upstream binding transcription factor, like
chr3_+_33367954 0.16 ENSDART00000103161
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr8_-_28259766 0.16 ENSDART00000134226
ENSDART00000087037
ENSDART00000136973
DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
chr14_+_23717165 0.16 ENSDART00000006373
Nedd4 family interacting protein 1
chr17_+_4325693 0.15 ENSDART00000154264
minichromosome maintenance 8 homologous recombination repair factor
chr1_-_23110740 0.15 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adhesion G protein-coupled receptor L3.1
chr3_-_31254379 0.15 ENSDART00000189376
actinoporin-like protein
chr23_-_17101360 0.15 ENSDART00000053418
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.1
chr4_-_2059233 0.14 ENSDART00000188177
ENSDART00000129521
ENSDART00000082289
cleavage and polyadenylation specific factor 6
chr14_+_23709134 0.14 ENSDART00000191162
ENSDART00000179754
ENSDART00000054266
glucosamine-6-phosphate deaminase 1
chr10_-_28513861 0.14 ENSDART00000177781
bobby sox homolog (Drosophila)
chr2_+_3403264 0.13 ENSDART00000105387
jumonji domain containing 4
chr17_-_7818944 0.13 ENSDART00000135538
ENSDART00000037541
required for meiotic nuclear division 1 homolog
chr10_+_22912251 0.13 ENSDART00000134790
mediator complex subunit 11
chr13_+_9612395 0.13 ENSDART00000136689
ENSDART00000138362
SMC5-SMC6 complex localization factor 2
chr7_-_23848012 0.13 ENSDART00000146104
ENSDART00000175108
si:ch211-200p22.4
chr5_+_25733774 0.13 ENSDART00000137088
ENSDART00000098467
abhydrolase domain containing 17B
chr2_-_24061575 0.13 ENSDART00000089234
solute carrier family 12 (potassium/chloride transporter), member 7a
chr21_-_32036597 0.13 ENSDART00000114964
zgc:165573
chr4_+_9011448 0.13 ENSDART00000192357
sorting and assembly machinery component 50 homolog, like
chr2_-_57264262 0.12 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
methyl-CpG binding domain protein 3a
chr19_+_2602903 0.12 ENSDART00000033132
family with sequence similarity 126, member A
chr8_-_47152001 0.12 ENSDART00000163922
ENSDART00000110512
ENSDART00000024320
Y box binding protein 1
chr23_-_18982499 0.12 ENSDART00000012507
bcl2-like 1
chr9_-_49805218 0.12 ENSDART00000179290
polypeptide N-acetylgalactosaminyltransferase 3
chr3_+_28831622 0.11 ENSDART00000184130
ENSDART00000191294
fleer
chr18_-_44331041 0.11 ENSDART00000168619
PR domain containing 10
chr22_+_18315490 0.11 ENSDART00000160413
GATA zinc finger domain containing 2Ab
chr3_-_30186296 0.11 ENSDART00000134395
ENSDART00000077057
ENSDART00000017422
TBC1 domain family, member 17
chr1_+_30723380 0.11 ENSDART00000127943
ENSDART00000062628
ENSDART00000127670
bora, aurora kinase A activator
chr12_-_33359052 0.11 ENSDART00000135943
solute carrier family 16 (monocarboxylate transporter), member 3
chr2_-_14390627 0.11 ENSDART00000172367
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr2_+_33926606 0.11 ENSDART00000111430
kinesin family member 2C
chr17_-_37184655 0.11 ENSDART00000180447
additional sex combs like transcriptional regulator 2
chr14_-_36437249 0.10 ENSDART00000016728
aspartylglucosaminidase
chr11_+_11030908 0.10 ENSDART00000111091
phospholipase A2 receptor 1
chr21_+_33459524 0.10 ENSDART00000053205
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr18_+_34601023 0.10 ENSDART00000149647
TCDD-inducible poly(ADP-ribose) polymerase
chr6_-_37441520 0.10 ENSDART00000132586
nitrilase family, member 2
chr16_+_54829574 0.10 ENSDART00000148392
poly(A) binding protein, cytoplasmic 1a
chr2_+_30960351 0.10 ENSDART00000141575
lipin 2
chr25_+_25737386 0.10 ENSDART00000108476
leucine rich repeat containing 61
chr18_-_2727764 0.10 ENSDART00000160841
si:ch211-248g20.5
chr8_-_36112278 0.10 ENSDART00000183283

chr16_+_43401005 0.10 ENSDART00000110994
squalene epoxidase a
chr12_+_35011899 0.09 ENSDART00000153007
ENSDART00000153020
QKI, KH domain containing, RNA binding 2
chr8_+_17868506 0.09 ENSDART00000175436
solute carrier family 44, member 5b
chr7_-_41420226 0.09 ENSDART00000074155
ATP-binding cassette, sub-family F (GCN20), member 2b
chr15_+_577698 0.09 ENSDART00000155799
si:ch73-144d13.4
chr20_-_47051996 0.09 ENSDART00000153330
DNA (cytosine-5-)-methyltransferase 3 alpha a
chr1_+_44395976 0.09 ENSDART00000159686
ENSDART00000189905
ENSDART00000025145
unc-93 homolog B1, TLR signaling regulator
chr6_+_11990733 0.09 ENSDART00000151075
bromodomain adjacent to zinc finger domain, 2Ba
chr12_-_19153177 0.09 ENSDART00000057125
thyrotrophic embryonic factor a
chr1_-_29061285 0.08 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gem (nuclear organelle) associated protein 8
chr16_-_42004544 0.08 ENSDART00000034544
caspase a
chr9_-_55772937 0.08 ENSDART00000159192
A kinase (PRKA) anchor protein 17A
chr9_-_32753535 0.08 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr24_-_18809433 0.08 ENSDART00000152009
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr9_-_1483879 0.08 ENSDART00000093415
RNA binding motif protein 45
chr9_+_29643036 0.08 ENSDART00000023210
ENSDART00000175160
tripartite motif containing 13
chr4_+_72798545 0.08 ENSDART00000181727
myelin regulatory factor-like
chr4_-_14486822 0.08 ENSDART00000048821
plexin b2a
chr2_-_43191465 0.08 ENSDART00000025254
cAMP responsive element modulator a
chr6_-_32314913 0.07 ENSDART00000051779
autophagy related 4C, cysteine peptidase
chr23_-_30960506 0.07 ENSDART00000142661
oxysterol binding protein-like 2a
chr19_+_32201991 0.07 ENSDART00000022667
family with sequence similarity 8, member A1a
chr3_-_11878490 0.07 ENSDART00000129961
coronin 7
chr11_+_43043171 0.07 ENSDART00000180344

chr15_-_25518084 0.07 ENSDART00000158594
hypoxia-inducible factor 1, alpha subunit, like
chr6_-_31325400 0.07 ENSDART00000188869
DnaJ (Hsp40) homolog, subfamily C, member 6
chr18_-_6881392 0.07 ENSDART00000154968
si:dkey-266m15.7
chr4_-_77506362 0.06 ENSDART00000174387
ENSDART00000181181

chr5_+_19448078 0.06 ENSDART00000088968
ubiquitin protein ligase E3B
chr10_-_11012000 0.06 ENSDART00000132995
adenylate kinase 3
chr21_+_43404945 0.06 ENSDART00000142234
FERM domain containing 7
chr20_+_32552912 0.06 ENSDART00000009691
Scm polycomb group protein like 4
chr3_+_46764022 0.06 ENSDART00000023814
protein kinase C substrate 80K-H
chr17_+_5985933 0.06 ENSDART00000190844
zgc:194275
chr17_+_28624321 0.06 ENSDART00000122260
HEAT repeat containing 5a
chr3_+_54761569 0.06 ENSDART00000135913
ENSDART00000180983
si:ch211-74m13.1
chr19_+_31585917 0.05 ENSDART00000132182
geminin, DNA replication inhibitor
chr17_-_40876680 0.05 ENSDART00000127200
SPT7-like STAGA complex gamma subunit
chr1_-_9641845 0.05 ENSDART00000121490
ENSDART00000159411
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
chr13_-_24429066 0.05 ENSDART00000147514
ENSDART00000057588
centrosomal protein 68
chr11_-_29650930 0.05 ENSDART00000166969
chromodomain helicase DNA binding protein 5
chr5_-_29559758 0.04 ENSDART00000051471
ENSDART00000167115
negative elongation factor complex member B
chr9_+_37850360 0.04 ENSDART00000185148
ENSDART00000082165
ENSDART00000133643
SEC22 homolog A, vesicle trafficking protein
chr8_+_10339869 0.04 ENSDART00000132253
TBC1 domain family, member 22B
chr24_-_20321012 0.04 ENSDART00000163683
mitogen-activated protein kinase kinase kinase 20
chr16_+_26738404 0.04 ENSDART00000163110
fibrinogen silencer binding protein
chr17_-_14451718 0.04 ENSDART00000039438
jnk1/mapk8 associated membrane protein
chr3_+_32443395 0.04 ENSDART00000188447
proline rich 12b
chr1_-_51719110 0.04 ENSDART00000190574
ribonuclease H2, subunit A
chr22_-_16755885 0.04 ENSDART00000036467
PATJ, crumbs cell polarity complex component
chr18_+_5454341 0.04 ENSDART00000192649
DTW domain containing 1
chr4_-_20313810 0.04 ENSDART00000136350
decapping mRNA 1B
chr19_+_31585341 0.04 ENSDART00000052185
geminin, DNA replication inhibitor
chr6_-_48473694 0.04 ENSDART00000154237
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr5_+_8246603 0.03 ENSDART00000167373
si:ch1073-475a24.1
chr24_-_4782052 0.03 ENSDART00000149911
angiotensin II receptor, type 1b
chr2_-_43123949 0.03 ENSDART00000075347
ENSDART00000132346
leucine rich repeat containing 6
chr17_-_25382367 0.03 ENSDART00000162306
ENSDART00000165282
LCK proto-oncogene, Src family tyrosine kinase
chr8_+_14890821 0.03 ENSDART00000190966
sterol O-acyltransferase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hmbox1a+zgc:91944

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.3 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 0.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.2 GO:0071674 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.1 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.2 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0019079 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0060907 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0035889 otolith tethering(GO:0035889)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 1.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138) toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.4 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.2 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.2 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0021742 abducens nucleus development(GO:0021742)
0.0 0.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) positive regulation of mRNA catabolic process(GO:0061014) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0045905 positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0036372 opsin transport(GO:0036372)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.2 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.2 GO:0044279 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0031956 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.1 0.3 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse