Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for hey2_hey1+heyl

Z-value: 0.66

Motif logo

Transcription factors associated with hey2_hey1+heyl

Gene Symbol Gene ID Gene Info
ENSDARG00000013441 hes-related family bHLH transcription factor with YRPW motif 2
ENSDARG00000055798 hes related family bHLH transcription factor with YRPW motif like
ENSDARG00000070538 hes-related family bHLH transcription factor with YRPW motif 1
ENSDARG00000112770 hes related family bHLH transcription factor with YRPW motif like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
heyldr11_v1_chr19_+_32553874_32553874-0.322.0e-01Click!
hey1dr11_v1_chr19_-_31802296_31802296-0.272.8e-01Click!
hey2dr11_v1_chr20_-_39596338_395963380.107.0e-01Click!

Activity profile of hey2_hey1+heyl motif

Sorted Z-values of hey2_hey1+heyl motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_68807170 1.12 ENSDART00000017849
hairy and enhancer of split related-7
chr7_+_38750871 0.86 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
coagulation factor II (thrombin)
chr17_+_24318753 0.83 ENSDART00000064083
orthodenticle homeobox 1
chr1_-_41192059 0.68 ENSDART00000084665
ENSDART00000135369
docking protein 7
chr2_-_49860723 0.64 ENSDART00000083690
biliverdin reductase A
chr7_+_31319876 0.63 ENSDART00000187611
family with sequence similarity 189, member A1
chr7_+_38717624 0.60 ENSDART00000132522
synaptotagmin XIII
chr1_-_13989643 0.59 ENSDART00000191046
E74-like factor 2b (ets domain transcription factor)
chr14_+_22076596 0.58 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr10_+_2684958 0.58 ENSDART00000112019
SET domain containing 9
chr5_-_32338866 0.57 ENSDART00000017956
ENSDART00000047670
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr7_+_29163762 0.56 ENSDART00000173762
solute carrier family 38, member 8b
chr21_-_36948 0.55 ENSDART00000181230
junction mediating and regulatory protein, p53 cofactor
chr1_+_31573225 0.54 ENSDART00000075286
solute carrier family 2 (facilitated glucose transporter), member 15b
chr23_+_2421689 0.54 ENSDART00000180200
t-complex 1
chr2_-_42375275 0.54 ENSDART00000026339
GTP binding protein 4
chr4_-_16824231 0.53 ENSDART00000014007
glycogen synthase 2
chr20_-_14665002 0.53 ENSDART00000152816
secernin 2
chr21_+_31150438 0.52 ENSDART00000065366
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_+_153146 0.52 ENSDART00000097468
zinc finger, GATA-like protein 1
chr4_-_16824556 0.50 ENSDART00000165289
ENSDART00000185839
glycogen synthase 2
chr18_+_14693682 0.49 ENSDART00000132249
URI1, prefoldin-like chaperone
chr11_+_3959495 0.46 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr8_-_21372446 0.46 ENSDART00000061481
ENSDART00000079293
elastase 2 like
chr9_-_12888082 0.46 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
chr21_+_31150773 0.45 ENSDART00000126205
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr3_+_1150348 0.45 ENSDART00000148524
nucleolar protein 12
chr8_+_26059677 0.45 ENSDART00000009178
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr7_+_32021982 0.44 ENSDART00000173848
methyltransferase like 15
chr25_-_35113891 0.43 ENSDART00000190724
zgc:165555
chr7_+_32021669 0.43 ENSDART00000173976
methyltransferase like 15
chr19_-_35361556 0.43 ENSDART00000012167
NADH dehydrogenase (ubiquinone) Fe-S protein 5
chr12_-_33359654 0.42 ENSDART00000001907
solute carrier family 16 (monocarboxylate transporter), member 3
chr21_+_39673157 0.40 ENSDART00000100240
mitochondrial rRNA methyltransferase 3b
chr23_+_2728095 0.40 ENSDART00000066086
zgc:114123
chr12_+_19384615 0.40 ENSDART00000078266
ribosomal L1 domain containing 1
chr16_-_40459104 0.39 ENSDART00000032389
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr23_+_2421313 0.39 ENSDART00000126038
t-complex 1
chr5_+_43470544 0.39 ENSDART00000111587
Rho-related BTB domain containing 2a
chr18_+_5875268 0.39 ENSDART00000177784
ENSDART00000122009
WD repeat domain 59
chr19_+_7152966 0.38 ENSDART00000080348
bromodomain containing 2a
chr15_-_17099560 0.37 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr14_-_26704829 0.37 ENSDART00000078563
neurogenin 1
chr21_+_1647990 0.36 ENSDART00000148540
ferrochelatase
chr10_+_29770120 0.36 ENSDART00000100032
ENSDART00000193205
hypoxia up-regulated 1
chr23_-_19686791 0.36 ENSDART00000161973
zgc:193598
chr4_-_178510 0.35 ENSDART00000169805
epidermal growth factor receptor pathway substrate 8
chr9_-_11587070 0.35 ENSDART00000030995
uridine monophosphate synthetase
chr25_-_36367523 0.34 ENSDART00000181344

chr1_+_17695426 0.34 ENSDART00000103236
ankyrin repeat domain 37
chr24_+_32668675 0.34 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
chr9_-_3149896 0.34 ENSDART00000020861
pyruvate dehydrogenase kinase, isozyme 1
chr17_+_53156530 0.34 ENSDART00000126277
ENSDART00000156774
diphthamine biosynthesis 6
chr15_-_44077937 0.33 ENSDART00000110112
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr16_-_48400639 0.32 ENSDART00000159372
eukaryotic translation initiation factor 3, subunit H, a
chr6_-_28222592 0.32 ENSDART00000131126
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr3_+_53773256 0.32 ENSDART00000170461
collagen, type V, alpha 3a
chr25_-_8625601 0.32 ENSDART00000155280
zgc:153343
chr5_+_27488975 0.32 ENSDART00000123635
secreted frizzled-related protein 1a
chr20_-_31496679 0.31 ENSDART00000153437
ENSDART00000153193
SAM and SH3 domain containing 1a
chr13_+_41917606 0.31 ENSDART00000114741
polymerase (RNA) I polypeptide B
chr24_+_31459715 0.31 ENSDART00000181102
ENSDART00000189950
ENSDART00000192321
ENSDART00000126380
cyclic nucleotide binding domain containing 1
chr7_+_74134010 0.30 ENSDART00000164874
claudin domain containing 1a
chr20_+_50115335 0.30 ENSDART00000031139
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr3_+_23029934 0.30 ENSDART00000110343
N-acetylglutamate synthase
chr14_+_14836468 0.30 ENSDART00000166728
si:dkey-102m7.3
chr7_-_41812015 0.30 ENSDART00000174058
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr7_-_30174882 0.30 ENSDART00000110409
FERM domain containing 5
chr7_-_41812355 0.29 ENSDART00000016105
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr24_-_38644937 0.29 ENSDART00000170194
solute carrier family 6, member 16b
chr18_-_5875433 0.29 ENSDART00000151727
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr19_-_13933204 0.29 ENSDART00000158059
tRNA selenocysteine 1 associated protein 1a
chr18_-_5103931 0.28 ENSDART00000188091
programmed cell death 10a
chr6_-_39919982 0.28 ENSDART00000065091
ENSDART00000064903
sulfatase modifying factor 1
chr24_+_42074143 0.28 ENSDART00000170514
DNA topoisomerase I mitochondrial
chr9_+_12887491 0.28 ENSDART00000102386
si:ch211-167j6.4
chr4_-_5912951 0.28 ENSDART00000169439
ADP-ribosylation factor-like 1
chr20_-_27733683 0.28 ENSDART00000103317
ENSDART00000138139
zgc:153157
chr16_+_19029297 0.27 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr25_+_37268900 0.27 ENSDART00000156737
si:dkey-234i14.6
chr1_-_26676391 0.27 ENSDART00000152492
tRNA methyltransferase O
chr1_-_26675969 0.27 ENSDART00000054184
tRNA methyltransferase O
chr18_+_6126506 0.27 ENSDART00000125725
si:ch1073-390k14.1
chr2_+_25839650 0.26 ENSDART00000134077
ENSDART00000140804
eukaryotic translation initiation factor 5A2
chr5_-_26247671 0.26 ENSDART00000145187
endoplasmic reticulum aminopeptidase 1b
chr5_-_26247215 0.26 ENSDART00000136806
endoplasmic reticulum aminopeptidase 1b
chr25_-_6223567 0.26 ENSDART00000067512
proteasome subunit alpha 4
chr19_-_34979837 0.26 ENSDART00000044838
N-myc downstream regulated 1a
chr5_-_26247973 0.25 ENSDART00000098527
endoplasmic reticulum aminopeptidase 1b
chr1_+_30946231 0.25 ENSDART00000022841
methionyl aminopeptidase type 1D (mitochondrial)
chr3_+_28939759 0.25 ENSDART00000141904
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr12_-_9516981 0.25 ENSDART00000106285
si:ch211-207i20.3
chr7_+_66048102 0.25 ENSDART00000104523
aryl hydrocarbon receptor nuclear translocator-like 1b
chr2_+_25839940 0.24 ENSDART00000139927
eukaryotic translation initiation factor 5A2
chr20_+_5065268 0.24 ENSDART00000053883
si:dkey-60a16.1
chr22_+_17261801 0.24 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr16_+_17252487 0.24 ENSDART00000063572
general transcription factor IIIC, polypeptide 6, alpha
chr9_+_3283608 0.24 ENSDART00000192275
histone acetyltransferase 1
chr20_-_25626693 0.24 ENSDART00000132247
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr14_-_52480661 0.23 ENSDART00000158353
exosome component 3
chr20_-_25626198 0.23 ENSDART00000126716
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr14_+_24935131 0.23 ENSDART00000170871
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr20_-_25626428 0.23 ENSDART00000136475
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr13_-_280652 0.23 ENSDART00000193627
solute carrier family 30 (zinc transporter), member 6
chr8_-_18582922 0.23 ENSDART00000123917
transmembrane protein 47
chr9_-_10804796 0.23 ENSDART00000134911
si:ch1073-416j23.1
chr18_-_11729 0.22 ENSDART00000159781
WAS protein homolog associated with actin, golgi membranes and microtubules
chr2_+_25840463 0.22 ENSDART00000125178
eukaryotic translation initiation factor 5A2
chr7_-_13362590 0.22 ENSDART00000091616
succinate dehydrogenase complex assembly factor 2
chr7_-_14535862 0.22 ENSDART00000112980
ENSDART00000135446
mitochondrial ribosomal protein S11
chr25_+_25123385 0.22 ENSDART00000163892
lactate dehydrogenase A4
chr9_-_403767 0.22 ENSDART00000167743
si:dkey-11f4.7
chr2_+_8780443 0.22 ENSDART00000137768
zinc finger, ZZ-type containing 3
chr2_-_11504347 0.22 ENSDART00000019392
short chain dehydrogenase/reductase family 16C, member 5a
chr7_+_14536083 0.21 ENSDART00000027331
mitochondrial ribosomal protein L46
chr9_-_10805231 0.21 ENSDART00000193913
ENSDART00000078348
si:ch1073-416j23.1
chr22_-_94352 0.21 ENSDART00000184883
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr8_+_39760258 0.21 ENSDART00000037914
cytochrome c oxidase subunit VIa polypeptide 1
chr22_-_38035084 0.21 ENSDART00000145029
peroxisomal biogenesis factor 6
chr8_-_26961779 0.20 ENSDART00000099214
solute carrier family 16 (monocarboxylate transporter), member 1b
chr20_-_29683754 0.20 ENSDART00000130599
ENSDART00000015928
ENSDART00000131219
si:ch211-195d17.2
chr18_+_5850837 0.20 ENSDART00000013150
component of oligomeric golgi complex 8
chr8_-_38317914 0.20 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr15_+_28410664 0.20 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr12_-_49168398 0.20 ENSDART00000186608

chr11_+_25485774 0.20 ENSDART00000026249
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr6_-_57476465 0.20 ENSDART00000128065
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr20_-_165818 0.20 ENSDART00000123860
si:ch211-241j12.3
chr23_+_25292147 0.19 ENSDART00000131486
proliferation-associated 2G4, b
chr22_-_38034852 0.19 ENSDART00000104613
peroxisomal biogenesis factor 6
chr22_-_94519 0.19 ENSDART00000161432
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr21_-_2322102 0.19 ENSDART00000162867
zgc:66483
chr13_-_280827 0.19 ENSDART00000144819
solute carrier family 30 (zinc transporter), member 6
chr2_-_32513538 0.19 ENSDART00000056640
ATP-binding cassette, sub-family F (GCN20), member 2a
chr22_-_20695237 0.19 ENSDART00000112722
oogenesis-related gene
chr24_-_20208474 0.19 ENSDART00000139329
cryptochrome DASH
chr4_-_5913338 0.18 ENSDART00000183590
ADP-ribosylation factor-like 1
chr16_+_22865942 0.18 ENSDART00000103235
ENSDART00000143957
flavin adenine dinucleotide synthetase 1
chr10_+_158590 0.18 ENSDART00000081982
potassium voltage-gated channel subfamily J member 15
chr12_-_33359052 0.18 ENSDART00000135943
solute carrier family 16 (monocarboxylate transporter), member 3
chr7_+_22801465 0.18 ENSDART00000052862
ENSDART00000173633
RNA binding motif protein 4.1
chr17_-_48705993 0.18 ENSDART00000030934
potassium channel, subfamily K, member 5a
chr21_+_40498628 0.18 ENSDART00000163454
coronin 6
chr24_-_42090635 0.18 ENSDART00000166413
signal sequence receptor, alpha
chr25_+_16945348 0.18 ENSDART00000016591
fibroblast growth factor 6a
chr5_+_4366431 0.18 ENSDART00000168560
ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr20_-_32405440 0.17 ENSDART00000062978
ENSDART00000153411
AFG1 like ATPase b
chr10_+_10972795 0.17 ENSDART00000127331
cell division cycle 37-like 1
chr7_-_41512999 0.17 ENSDART00000173577
si:dkey-10f23.2
chr22_-_18779232 0.17 ENSDART00000186726
ATP synthase F1 subunit delta
chr12_-_30359031 0.17 ENSDART00000192628
tudor domain containing 1
chr10_+_5268054 0.17 ENSDART00000114491
receptor tyrosine kinase-like orphan receptor 2
chr3_-_62380146 0.17 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr18_+_38191346 0.16 ENSDART00000052703
nucleobindin 2b
chr20_+_25626479 0.16 ENSDART00000143883
phosphoribosyl pyrophosphate amidotransferase
chr20_-_13140309 0.16 ENSDART00000020703
ENSDART00000188594
integrator complex subunit 7
chr9_+_42066030 0.16 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr20_+_38458084 0.16 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr18_+_40993369 0.16 ENSDART00000141162
si:dkey-283j8.1
chr12_+_33975065 0.16 ENSDART00000036649
sideroflexin 2
chr19_-_32518556 0.16 ENSDART00000103410
zinc finger and BTB domain containing 8B
chr25_-_35101396 0.16 ENSDART00000138865
zgc:162611
chr13_-_31370184 0.16 ENSDART00000034829
ribosomal RNA processing 12 homolog
chr25_-_35101673 0.16 ENSDART00000140864
zgc:162611
chr11_-_44194132 0.16 ENSDART00000182954
ENSDART00000111271

chr9_-_14137295 0.16 ENSDART00000127640
ENSDART00000189018
ENSDART00000188985
tubulin tyrosine ligase-like family, member 4
chr18_+_40993196 0.16 ENSDART00000115111
si:dkey-283j8.1
chr19_-_5103313 0.16 ENSDART00000037007
triosephosphate isomerase 1a
chr7_+_40148492 0.15 ENSDART00000110789
extended synaptotagmin-like protein 2b
chr20_-_25486384 0.15 ENSDART00000141340
si:dkey-183n20.15
chr10_+_41159241 0.15 ENSDART00000141657
annexin A4
chr13_+_35925490 0.15 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr20_+_32406011 0.15 ENSDART00000018640
ENSDART00000137910
sorting nexin 3
chr18_+_5490668 0.15 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr9_-_12594759 0.15 ENSDART00000021266
transformer 2 beta homolog
chr5_-_33959868 0.15 ENSDART00000143652
zgc:63972
chr1_-_19648227 0.15 ENSDART00000054574
polymerase (RNA) I polypeptide E
chr3_+_54887782 0.14 ENSDART00000018205
arylalkylamine N-acetyltransferase 2
chr1_-_157563 0.14 ENSDART00000018741
PCI domain containing 2
chr14_-_498979 0.14 ENSDART00000171976
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr8_-_39977026 0.14 ENSDART00000141707
aspartate beta-hydroxylase domain containing 2
chr7_-_6340998 0.14 ENSDART00000172884
zgc:165555
chr19_+_32822269 0.14 ENSDART00000052097
ENSDART00000052096
ENSDART00000188012
reactive intermediate imine deaminase A homolog
chr15_+_6652396 0.14 ENSDART00000192813
ENSDART00000157678
NOP53 ribosome biogenesis factor
chr5_-_13167097 0.14 ENSDART00000149700
ENSDART00000030213
mitogen-activated protein kinase 1
chr8_+_23213320 0.14 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr11_+_45299447 0.14 ENSDART00000172999
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr9_-_35557397 0.14 ENSDART00000100681
neural cell adhesion molecule 2
chr17_-_24879003 0.13 ENSDART00000123147
zinc finger and BTB domain containing 8A
chr7_-_16034324 0.13 ENSDART00000002498
ENSDART00000162962
elongator acetyltransferase complex subunit 4
chr7_+_16033923 0.13 ENSDART00000161669
ENSDART00000114062
inner mitochondrial membrane peptidase subunit 1
chr17_+_52612866 0.13 ENSDART00000182828
ENSDART00000191156
ENSDART00000188814
ENSDART00000109891
angel homolog 1 (Drosophila)
chr11_+_25328199 0.13 ENSDART00000141478
ENSDART00000112209
family with sequence similarity 83, member D
chr8_+_21159122 0.13 ENSDART00000033491
SPRY domain containing 4
chr24_+_42129775 0.13 ENSDART00000181576
WW domain containing E3 ubiquitin protein ligase 1
chr9_+_907459 0.13 ENSDART00000034850
ENSDART00000144114
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr8_+_23738122 0.13 ENSDART00000062983
ribosomal protein L10a
chr11_-_438294 0.13 ENSDART00000040812
NUF2, NDC80 kinetochore complex component, homolog
chr7_+_67467702 0.13 ENSDART00000168460
ENSDART00000170322
ribosomal protein L13
chr19_-_791016 0.13 ENSDART00000037515
misato 1, mitochondrial distribution and morphology regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of hey2_hey1+heyl

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0006953 acute-phase response(GO:0006953)
0.1 0.4 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.7 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.3 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.9 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.2 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.5 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.4 GO:0021516 dorsal spinal cord development(GO:0021516) anterior lateral line nerve development(GO:0048909)
0.1 0.6 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.6 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 0.8 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.3 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.2 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.2 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.2 GO:0072388 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.1 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.2 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.4 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.1 GO:0003156 regulation of organ formation(GO:0003156)
0.0 0.2 GO:0032206 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.4 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.2 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.0 0.2 GO:0097032 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 1.1 GO:0001757 somite specification(GO:0001757)
0.0 0.9 GO:0009749 response to glucose(GO:0009749)
0.0 0.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.1 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0030719 P granule organization(GO:0030719)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0019478 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.0 0.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.6 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.5 GO:0048599 oocyte development(GO:0048599)
0.0 0.7 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0019079 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.0 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.1 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.0 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.0 0.0 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.4 GO:0009648 photoperiodism(GO:0009648)
0.0 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.0 GO:0060585 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 1.4 GO:0006364 rRNA processing(GO:0006364)
0.0 0.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.3 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.2 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3 1.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 0.7 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.3 GO:0034618 arginine binding(GO:0034618)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.5 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 0.2 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.1 0.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 0.2 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.2 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.0 GO:0031708 endothelin B receptor binding(GO:0031708)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport