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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4

Z-value: 0.17

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Transcription factors associated with her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4

Gene Symbol Gene ID Gene Info
ENSDARG00000002707 hairy-related 11
ENSDARG00000008796 hairy-related 5
ENSDARG00000014722 hairy-related 1
ENSDARG00000009822 hairy-related 4, tandem duplicate 4
ENSDARG00000032963 hairy-related 12
ENSDARG00000038205 hairy-related 2
ENSDARG00000054560 hairy and enhancer of split-related 15, tandem duplicate 2
ENSDARG00000054562 hairy and enhancer of split-related 15, tandem duplicate 1
ENSDARG00000056729 hairy-related 4, tandem duplicate 2
ENSDARG00000056732 hairy-related 4, tandem duplicate 1
ENSDARG00000070770 hairy-related 4, tandem duplicate 3
ENSDARG00000094426 hairy-related 4, tandem duplicate 2

Activity profile of her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4 motif

Sorted Z-values of her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_62723233 0.78 ENSDART00000183718
nanos homolog 2
chr16_-_45069882 0.77 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr14_+_46313135 0.49 ENSDART00000172902
crystallin, beta A1, like 1
chr7_-_40993456 0.35 ENSDART00000031700
engrailed homeobox 2a
chr10_-_27566481 0.31 ENSDART00000078920
autism susceptibility candidate 2a
chr2_+_29976419 0.29 ENSDART00000056748
engrailed homeobox 2b
chr14_+_46313396 0.20 ENSDART00000047525
crystallin, beta A1, like 1
chr6_+_39184236 0.16 ENSDART00000156187
tachykinin 3b
chr11_-_3959477 0.13 ENSDART00000045971
polybromo 1
chr9_+_3283608 0.12 ENSDART00000192275
histone acetyltransferase 1
chr11_-_3959889 0.11 ENSDART00000159683
polybromo 1
chr19_+_31183495 0.11 ENSDART00000088618
mesenchyme homeobox 2b
chr5_-_46329880 0.11 ENSDART00000156577
si:ch211-130m23.5
chr15_-_14469704 0.11 ENSDART00000185077
numb homolog (Drosophila)-like
chr8_+_39760258 0.11 ENSDART00000037914
cytochrome c oxidase subunit VIa polypeptide 1
chr19_+_42470396 0.10 ENSDART00000191679
si:dkey-166k12.1
chr4_-_8093753 0.10 ENSDART00000133434
WNK lysine deficient protein kinase 1b
chr23_+_21459263 0.09 ENSDART00000104209
hairy-related 4, tandem duplicate 3
chr9_-_44295071 0.09 ENSDART00000011837
neuronal differentiation 1
chr14_+_14836468 0.08 ENSDART00000166728
si:dkey-102m7.3
chr11_+_3959495 0.08 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr3_+_32425202 0.07 ENSDART00000156464
proline rich 12b
chr6_+_49021703 0.07 ENSDART00000149394
solute carrier family 16 (monocarboxylate transporter), member 1a
chr4_-_44611273 0.06 ENSDART00000156793
zinc finger protein 1115
chr19_+_42142381 0.05 ENSDART00000129915
potassium voltage-gated channel, KQT-like subfamily, member 4
chr19_-_35596207 0.05 ENSDART00000136811
collagen, type VIII, alpha 2
chr9_+_45789887 0.05 ENSDART00000135202
si:dkey-34f9.3
chr23_-_21463788 0.04 ENSDART00000079265
hairy-related 4, tandem duplicate 4
chr19_+_42469058 0.04 ENSDART00000076915
si:dkey-166k12.1
chr8_-_39760427 0.04 ENSDART00000184336
ENSDART00000186500
si:ch211-170d8.8
chr20_-_39344116 0.04 ENSDART00000037282
coiled-coil domain containing 25
chr14_-_30387894 0.03 ENSDART00000176136
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr2_-_32386791 0.03 ENSDART00000056634
upstream binding transcription factor, like
chr8_+_29593986 0.03 ENSDART00000077642
atonal bHLH transcription factor 1a
chr1_+_5576151 0.02 ENSDART00000109756
carboxypeptidase O
chr11_+_29671661 0.02 ENSDART00000024318
ENSDART00000165024
ring finger protein 207a
chr12_+_30046320 0.02 ENSDART00000179904
ENSDART00000153394
actin binding LIM protein 1b
chr20_+_19212962 0.00 ENSDART00000063706
fibronectin type III domain containing 4a

Network of associatons between targets according to the STRING database.

First level regulatory network of her1+her11+her5_her12+her15.1+her15.2+her2+her4.1+her4.2+her4.3+her4.4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.8 GO:0006096 glycolytic process(GO:0006096)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016586 RSC complex(GO:0016586)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis