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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for gmeb1

Z-value: 0.30

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Transcription factors associated with gmeb1

Gene Symbol Gene ID Gene Info
ENSDARG00000062060 glucocorticoid modulatory element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gmeb1dr11_v1_chr19_+_16068445_16068445-0.331.8e-01Click!

Activity profile of gmeb1 motif

Sorted Z-values of gmeb1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_11649690 1.06 ENSDART00000149713
BTB (POZ) domain containing 16
chr5_+_30588856 0.95 ENSDART00000086661
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr5_-_30588539 0.85 ENSDART00000086686
ENSDART00000159163
ENSDART00000142958
c2cd2-like
chr16_-_24815091 0.66 ENSDART00000154269
ENSDART00000131025
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr25_+_34845115 0.62 ENSDART00000061996
transmembrane protein 231
chr9_-_306515 0.51 ENSDART00000166059
si:ch211-166e11.5
chr11_+_35364445 0.49 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr4_-_17642168 0.42 ENSDART00000007030
kelch-like family, member 42
chr14_-_26400501 0.40 ENSDART00000054189
Pim proto-oncogene, serine/threonine kinase, related 212
chr5_-_67993086 0.38 ENSDART00000049331
general transcription factor IIIAa
chr21_-_8153165 0.37 ENSDART00000182580

chr3_-_16000168 0.33 ENSDART00000160628
NME/NM23 nucleoside diphosphate kinase 3
chr14_-_21932403 0.33 ENSDART00000054420
RAD9 checkpoint clamp component A
chr4_+_45148652 0.32 ENSDART00000150798
si:dkey-51d8.9
chr3_-_15999501 0.31 ENSDART00000160668
NME/NM23 nucleoside diphosphate kinase 3
chr25_+_36045072 0.29 ENSDART00000126326
RPGRIP1-like
chr20_+_22666548 0.28 ENSDART00000147520
ligand of numb-protein X 1
chr10_+_39091716 0.28 ENSDART00000193072
si:ch73-1a9.4
chr4_-_25485404 0.25 ENSDART00000041402
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr9_-_28103097 0.24 ENSDART00000146284
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr4_-_25485214 0.23 ENSDART00000159941
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr20_-_27381691 0.23 ENSDART00000010293
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a
chr8_+_10305400 0.23 ENSDART00000172400
Pim-1 proto-oncogene, serine/threonine kinase
chr16_+_23397785 0.22 ENSDART00000148961
S100 calcium binding protein A10b
chr14_-_8795081 0.17 ENSDART00000106671
transforming growth factor, beta 2, like
chr2_-_3045861 0.17 ENSDART00000105818
ENSDART00000187575
guanylate kinase 1a
chr5_+_6955900 0.14 ENSDART00000099417

chr10_-_20523405 0.12 ENSDART00000114824
DDHD domain containing 2
chr1_+_17676745 0.09 ENSDART00000030665
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr20_+_27427112 0.09 ENSDART00000153459
si:dkey-22l1.1
chr21_+_6397463 0.05 ENSDART00000136539
si:ch211-225g23.1
chr17_-_25831569 0.03 ENSDART00000148743
hedgehog acyltransferase
chr25_-_36044583 0.02 ENSDART00000073432
retinoblastoma-like 2 (p130)
chr2_-_5399437 0.02 ENSDART00000132411
si:ch1073-184j22.2

Network of associatons between targets according to the STRING database.

First level regulatory network of gmeb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.6 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0051503 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.4 GO:1990798 pancreas regeneration(GO:1990798)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.0 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels