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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for gli2a+gli3

Z-value: 0.29

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Transcription factors associated with gli2a+gli3

Gene Symbol Gene ID Gene Info
ENSDARG00000025641 GLI family zinc finger 2a
ENSDARG00000052131 GLI family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gli2adr11_v1_chr9_+_37152564_371525640.924.8e-08Click!
gli3dr11_v1_chr24_-_11821505_118215050.608.4e-03Click!

Activity profile of gli2a+gli3 motif

Sorted Z-values of gli2a+gli3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_27340682 0.60 ENSDART00000011305
dipeptidyl-peptidase 3
chr25_+_30298377 0.54 ENSDART00000153622
chromosome 11 open reading frame 96
chr16_+_52512025 0.48 ENSDART00000056095
fatty acid binding protein 10a, liver basic
chr25_+_245438 0.48 ENSDART00000004689
zgc:92481
chr20_-_39596338 0.46 ENSDART00000023531
hes-related family bHLH transcription factor with YRPW motif 2
chr5_-_38643188 0.44 ENSDART00000144972
si:ch211-271e10.1
chr3_+_55114097 0.40 ENSDART00000121686
hemoglobin beta embryonic-1.1
chr18_-_17485419 0.40 ENSDART00000018764
forkhead box L1
chr20_-_25626693 0.40 ENSDART00000132247
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr23_+_31245395 0.38 ENSDART00000053588
interleukin-1 receptor-associated kinase 1 binding protein 1
chr5_-_10012971 0.38 ENSDART00000179421

chr13_+_15682803 0.38 ENSDART00000188063

chr6_-_35446110 0.37 ENSDART00000058773
regulator of G protein signaling 16
chr4_-_5831036 0.35 ENSDART00000166232
forkhead box M1
chr24_+_35827766 0.35 ENSDART00000144700
si:dkeyp-7a3.1
chr17_-_8562586 0.35 ENSDART00000154257
ENSDART00000157308
frizzled class receptor 3b
chr12_-_17479078 0.35 ENSDART00000079115
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr22_-_11714104 0.33 ENSDART00000145265
ENSDART00000063127
ENSDART00000183743
crystallin, gamma S1
chr15_-_35252522 0.32 ENSDART00000144153
ENSDART00000059195
mitochondrial fission factor
chr10_+_18952271 0.31 ENSDART00000146517
dihydropyrimidinase-like 2b
chr22_-_188102 0.30 ENSDART00000125391
ENSDART00000170463

chr1_-_19845378 0.30 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
glyoxylate reductase/hydroxypyruvate reductase b
chr23_+_44374041 0.29 ENSDART00000136056
eph receptor B4b
chr19_-_10243148 0.29 ENSDART00000148073
shisa family member 7
chr21_-_30415524 0.28 ENSDART00000101036
GrpE-like 2, mitochondrial
chr23_+_20422661 0.28 ENSDART00000144047
ENSDART00000104336
troponin C type 2 (fast)
chr5_+_20693724 0.27 ENSDART00000141368
si:ch211-240b21.2
chr8_-_52859301 0.27 ENSDART00000162004
nuclear receptor subfamily 5, group A, member 1a
chr10_+_26747755 0.26 ENSDART00000100329
coagulation factor IXb
chr10_-_36726188 0.26 ENSDART00000157262
Pim proto-oncogene, serine/threonine kinase, related 137
chr3_+_55122662 0.26 ENSDART00000128380
hemoglobin beta embryonic-1.2
chr4_-_75175407 0.26 ENSDART00000180125

chr1_+_10129099 0.25 ENSDART00000187740
RNA binding motif protein 46
chr20_+_15552657 0.25 ENSDART00000063912
Jun proto-oncogene, AP-1 transcription factor subunit
chr3_+_55131289 0.24 ENSDART00000111585

chr22_+_38173960 0.24 ENSDART00000010537
ceruloplasmin
chr5_-_43959972 0.24 ENSDART00000180517
si:ch211-204c21.1
chr14_-_215051 0.24 ENSDART00000054822
NK3 homeobox 2
chr4_-_52165969 0.23 ENSDART00000171130
si:dkeyp-44b5.4
chr13_+_30804367 0.23 ENSDART00000053946
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr10_-_8358396 0.23 ENSDART00000059322
chondroitin sulfate N-acetylgalactosaminyltransferase 1a
chr8_-_47800754 0.23 ENSDART00000115050
ENSDART00000133669
KN motif and ankyrin repeat domains 3
chr18_-_14836600 0.22 ENSDART00000045232
metastasis suppressor 1-like a
chr1_-_46862190 0.22 ENSDART00000145167
1-acylglycerol-3-phosphate O-acyltransferase 3
chr8_-_7078575 0.22 ENSDART00000137413
si:ch73-233m11.2
chr12_+_27117609 0.21 ENSDART00000076154
homeobox B8b
chr4_+_57881965 0.21 ENSDART00000162234
si:dkeyp-44b5.4
chr6_+_7123980 0.21 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
chr1_+_7956030 0.21 ENSDART00000159655

chr24_+_7828613 0.20 ENSDART00000135161
zgc:101569
chr4_-_20208166 0.20 ENSDART00000066891
gamma-secretase activating protein
chr4_-_18454591 0.19 ENSDART00000185200
SCO2 cytochrome c oxidase assembly protein
chr9_+_23770666 0.19 ENSDART00000182493
si:ch211-219a4.3
chr19_-_40192249 0.19 ENSDART00000051972
granulin 1
chr13_-_31346392 0.18 ENSDART00000134343
ribosomal RNA processing 12 homolog
chr1_+_51479128 0.18 ENSDART00000028018
Meis homeobox 1 a
chr5_-_23179319 0.17 ENSDART00000161883
ENSDART00000136260
si:dkey-114c15.5
chr24_-_25184553 0.16 ENSDART00000166917
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr17_+_6563307 0.15 ENSDART00000156454
adhesion G protein-coupled receptor F3a
chr5_-_15948833 0.15 ENSDART00000051649
ENSDART00000124467
X-box binding protein 1
chr21_+_35327589 0.15 ENSDART00000145191
ENSDART00000132743
arginyl-tRNA synthetase
chr6_-_18560190 0.15 ENSDART00000168636
transcription elongation factor, mitochondrial
chr10_+_28428222 0.15 ENSDART00000135003
si:ch211-222e20.4
chr6_-_35106425 0.14 ENSDART00000165139
nitric oxide synthase 1 (neuronal) adaptor protein a
chr23_+_31979602 0.14 ENSDART00000140351
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr19_+_10860485 0.14 ENSDART00000169962
si:ch73-347e22.4
chr10_-_22854758 0.13 ENSDART00000079449
actinodin3
chr13_+_42124566 0.13 ENSDART00000074707
CDC42 effector protein (Rho GTPase binding) 3
chr25_+_22730490 0.13 ENSDART00000149455
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr4_+_5132951 0.13 ENSDART00000103279
cyclin D2, b
chr8_+_29962635 0.13 ENSDART00000007640
patched 1
chr21_-_45073764 0.12 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr9_+_50007556 0.12 ENSDART00000175587
solute carrier family 38, member 11
chr12_+_18358082 0.12 ENSDART00000123315
si:dkey-7e14.3
chr13_+_3954540 0.11 ENSDART00000092646
leucine rich repeat containing 73
chr6_-_10693111 0.11 ENSDART00000187206
ENSDART00000192319
dynein, axonemal, heavy polypeptide 9 like
chr6_-_10320676 0.11 ENSDART00000151247
sodium channel, voltage-gated, type I like, alpha b
chr21_-_30935262 0.10 ENSDART00000172390
stromal interaction molecule 1b
chr25_+_7461624 0.10 ENSDART00000170569
synaptotagmin XII
chr23_+_28582865 0.10 ENSDART00000020296
L1 cell adhesion molecule, paralog a
chr14_-_29859067 0.10 ENSDART00000136380
sorbin and SH3 domain containing 2b
chr25_-_28384954 0.10 ENSDART00000073500
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr25_-_210730 0.10 ENSDART00000187580

chr9_+_6587364 0.10 ENSDART00000122279
four and a half LIM domains 2a
chr4_+_47656992 0.09 ENSDART00000161148
zinc finger protein 1040
chr19_+_56351 0.09 ENSDART00000168334
collagen, type XIV, alpha 1b
chr20_-_33959815 0.09 ENSDART00000133081
selectin P
chr22_-_12726556 0.09 ENSDART00000105776
family with sequence similarity 207, member A
chr12_-_26582607 0.09 ENSDART00000045186
solute carrier family 16 (monocarboxylate transporter), member 5a
chr19_-_26235219 0.09 ENSDART00000104008
dystrobrevin binding protein 1b
chr8_-_18316482 0.09 ENSDART00000190156
ring finger protein 220b
chr17_+_15388479 0.09 ENSDART00000052439
si:ch211-266g18.6
chr16_+_37470717 0.08 ENSDART00000112003
ENSDART00000188431
ENSDART00000192837
adhesion G protein-coupled receptor B1a
chr9_+_6587056 0.08 ENSDART00000193421
four and a half LIM domains 2a
chr16_-_38067952 0.08 ENSDART00000114266
pleckstrin homology domain containing, family O member 1b
chr14_+_25465346 0.08 ENSDART00000173436
si:dkey-280e21.3
chr10_+_2232023 0.08 ENSDART00000097695
contactin associated protein like 3
chr7_-_15413188 0.08 ENSDART00000185980
si:ch211-106j24.1
chr17_+_30587333 0.08 ENSDART00000156500
NHS-like 1a
chr18_-_2639351 0.07 ENSDART00000168106
RELT, TNF receptor
chr24_-_6258869 0.07 ENSDART00000006636
ENSDART00000178667
myosin IIIA
chr8_-_14484599 0.07 ENSDART00000057644
LIM homeobox 4
chr10_+_40235959 0.07 ENSDART00000145862
GRAM domain containing 1Ba
chr23_-_41824460 0.07 ENSDART00000131235
si:ch73-302a13.2
chr22_-_24818066 0.07 ENSDART00000143443
vitellogenin 6
chr22_+_1751640 0.07 ENSDART00000162093
zinc finger protein 1169
chr18_+_5273953 0.07 ENSDART00000165073
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr23_+_43834376 0.07 ENSDART00000148989
si:ch211-149b19.4
chr1_+_9557212 0.07 ENSDART00000111131
extracellular leucine-rich repeat and fibronectin type III domain containing 1b
chr10_-_24868581 0.07 ENSDART00000193055

chr13_-_50624173 0.07 ENSDART00000184181
ventral homeobox
chr8_-_19216657 0.06 ENSDART00000135096
ENSDART00000135869
ENSDART00000145951
si:ch73-222f22.2
si:ch73-222f22.2
chr13_-_45201300 0.06 ENSDART00000074750
ENSDART00000180265
runt-related transcription factor 3
chr19_-_10631482 0.06 ENSDART00000129264
si:dkey-211g8.9
chr21_-_26520629 0.06 ENSDART00000142731
Ras converting CAAX endopeptidase 1b
chr7_-_8374950 0.06 ENSDART00000057101
aerolysin-like protein
chr25_-_24247584 0.06 ENSDART00000046349
SPT2 chromatin protein domain containing 1
chr20_+_26095530 0.06 ENSDART00000139350
spectrin repeat containing, nuclear envelope 1a
chr15_+_42431198 0.06 ENSDART00000189951
ENSDART00000089694
T cell lymphoma invasion and metastasis 1b
chr15_+_16525126 0.06 ENSDART00000193455
polypeptide N-acetylgalactosaminyltransferase 17
chr16_-_30847192 0.06 ENSDART00000191106
ENSDART00000128158
protein tyrosine kinase 2ab
chr3_-_51109286 0.06 ENSDART00000172010
si:ch211-148f13.1
chr3_+_5083407 0.05 ENSDART00000146883
si:ch73-338o16.4
chr15_-_47812268 0.05 ENSDART00000190231
transmembrane O-methyltransferase
chr25_-_35106751 0.05 ENSDART00000180682
ENSDART00000073457
zgc:194989
chr12_-_464007 0.05 ENSDART00000106669
dehydrogenase/reductase (SDR family) member 7Cb
chr4_-_43822179 0.05 ENSDART00000185246
si:dkey-261p22.1
chr6_-_8480815 0.05 ENSDART00000162300
RAS protein activator like 3
chr10_-_1827225 0.05 ENSDART00000058627
erythrocyte membrane protein band 4.1 like 4A
chr13_-_40726865 0.05 ENSDART00000099847
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr7_-_15413019 0.05 ENSDART00000172147
si:ch211-106j24.1
chr21_+_43402794 0.04 ENSDART00000185572
FERM domain containing 7
chr10_+_22854803 0.04 ENSDART00000079437
adaptor-related protein complex 4, mu 1 subunit
chr17_-_42213822 0.04 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr8_+_28467893 0.04 ENSDART00000189724
solute carrier family 52 (riboflavin transporter), member 3
chr17_-_7371564 0.04 ENSDART00000060336
RAB32b, member RAS oncogene family
chr4_+_72797711 0.04 ENSDART00000190934
ENSDART00000163236
myelin regulatory factor-like
chr7_+_73801377 0.04 ENSDART00000184051
si:ch73-252p3.1
chr9_-_1984604 0.04 ENSDART00000082339
homeobox D12a
chr6_-_43817761 0.04 ENSDART00000183945
forkhead box P1b
chr18_+_33100606 0.04 ENSDART00000003907
si:ch211-229c8.13
chr20_-_7000225 0.04 ENSDART00000100098
adenylate cyclase 1a
chr14_+_46020282 0.04 ENSDART00000190087
C1q and TNF related 2
chr20_+_2669017 0.04 ENSDART00000058777
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr14_+_34952883 0.04 ENSDART00000182812
interleukin 12Ba
chr13_+_24842857 0.04 ENSDART00000123866
dual specificity phosphatase 13a
chr7_+_73780936 0.04 ENSDART00000092691
proliferation and apoptosis adaptor protein 15
chr10_-_40448736 0.04 ENSDART00000137644
ENSDART00000168190
trace amine associated receptor 20p
chr6_+_54358529 0.03 ENSDART00000153704
ankyrin repeat and sterile alpha motif domain containing 1Ab
chr12_+_24562667 0.03 ENSDART00000056256
neurexin 1a
chr21_+_10739846 0.03 ENSDART00000084011
complexin 4a
chr13_-_12602920 0.03 ENSDART00000102311
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr14_+_43554490 0.03 ENSDART00000060351
adrenoceptor alpha 1Bb
chr17_+_31580960 0.03 ENSDART00000188157
si:dkey-13p1.4
chr2_-_33993533 0.03 ENSDART00000140910
ENSDART00000077304
patched 2
chr25_+_25085349 0.03 ENSDART00000192166
si:ch73-182e20.4
chr5_+_20437124 0.03 ENSDART00000159001
transmembrane protein 119a
chr5_+_68878124 0.03 ENSDART00000139933
southpaw
chr16_-_31644545 0.03 ENSDART00000181634

chr21_-_5856050 0.02 ENSDART00000115367

chr21_+_22985078 0.02 ENSDART00000156491
lysophosphatidic acid receptor 6b
chr19_+_14158075 0.02 ENSDART00000170335
ENSDART00000168260
nudC nuclear distribution protein
chr16_-_37964325 0.02 ENSDART00000148801
melanocortin 2 receptor accessory protein 2a
chr4_-_56157199 0.02 ENSDART00000169806
si:ch211-207e19.15
chr8_-_49201258 0.02 ENSDART00000114584
ENSDART00000142172
zgc:171501
chr10_-_44482911 0.02 ENSDART00000085556
huntingtin interacting protein 1 related a
chr23_+_12072980 0.02 ENSDART00000141646
endothelin 3b
chr12_+_34273240 0.02 ENSDART00000037904
suppressor of cytokine signaling 3b
chr6_-_15639087 0.02 ENSDART00000128940
ENSDART00000183092
melanophilin a
chr17_-_34952562 0.02 ENSDART00000021128
kinase D-interacting substrate 220a
chr3_-_19091024 0.02 ENSDART00000188485
ENSDART00000110554
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr22_-_24791505 0.01 ENSDART00000136837
vitellogenin 4
chr3_+_23692462 0.01 ENSDART00000145934
homeobox B7a
chr22_-_10487490 0.01 ENSDART00000064798
asporin (LRR class 1)
chr17_+_6585333 0.01 ENSDART00000124293
adhesion G protein-coupled receptor F3a
chr20_+_27194833 0.01 ENSDART00000150072
si:dkey-85n7.8
chr20_+_10498704 0.01 ENSDART00000192985
zgc:100997
chr13_+_3252950 0.01 ENSDART00000020671
peripherin 2b (retinal degeneration, slow)
chr20_-_915234 0.01 ENSDART00000164816
cannabinoid receptor 1
chr15_-_38361787 0.01 ENSDART00000155758
transient receptor potential cation channel, subfamily C, member 2a
chr8_+_48558100 0.01 ENSDART00000166165
si:ch211-215j19.12
chr14_+_25464681 0.01 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr10_+_15224660 0.01 ENSDART00000137932
SH3-domain binding protein 2
chr4_+_38937575 0.01 ENSDART00000150385
zinc finger protein 997
chr3_+_57991074 0.01 ENSDART00000076077
myeloid-associated differentiation marker-like 2
chr2_+_26656283 0.01 ENSDART00000133202
ENSDART00000099208
aspartate beta-hydroxylase
chr18_+_9641210 0.01 ENSDART00000182024
piccolo presynaptic cytomatrix protein b
chr25_-_17403598 0.01 ENSDART00000104216
cytochrome P450, family 2, subfamily X, polypeptide 9
chr15_+_1137337 0.01 ENSDART00000191508
purinergic receptor P2Y13
chr6_-_49655879 0.01 ENSDART00000191594
adenomatosis polyposis coli down-regulated 1-like
chr9_-_12736089 0.01 ENSDART00000088042
myosin X-like 3
chr22_+_38762693 0.00 ENSDART00000015016
ENSDART00000150187
alkaline phosphatase, intestinal, tandem duplicate 1
chr13_-_15799391 0.00 ENSDART00000124688
BCL2 associated athanogene 5
chr5_+_51594209 0.00 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
creatine kinase, mitochondrial 2b (sarcomeric)
chr4_+_45274792 0.00 ENSDART00000150295
zinc finger protein 1138
chr25_+_32473433 0.00 ENSDART00000152326
sulfide quinone oxidoreductase
chr8_+_31119548 0.00 ENSDART00000136578
synapsin I
chr17_-_51202339 0.00 ENSDART00000167117
si:ch1073-469d17.2
chr9_-_33136990 0.00 ENSDART00000131742
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3b
chr4_-_17741513 0.00 ENSDART00000141680
myosin binding protein C, slow type

Network of associatons between targets according to the STRING database.

First level regulatory network of gli2a+gli3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.1 0.3 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.2 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.1 0.2 GO:0048785 hatching gland development(GO:0048785)
0.0 0.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.1 GO:0060155 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.0 0.2 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.1 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.5 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction