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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxo3a

Z-value: 0.41

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Transcription factors associated with foxo3a

Gene Symbol Gene ID Gene Info
foxo3a
ENSDARG00000023058 forkhead box O3A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxo3adr11_v1_chr17_+_6793001_67930010.814.5e-05Click!

Activity profile of foxo3a motif

Sorted Z-values of foxo3a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_4256300 1.48 ENSDART00000103319
ENSDART00000150279
cd9b
CD9 molecule b
chr22_-_28777557 1.33 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr22_-_28777374 1.25 ENSDART00000188206
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr7_+_33372680 1.22 ENSDART00000193436
ENSDART00000099988
glceb
glucuronic acid epimerase b
chr18_+_15271993 1.20 ENSDART00000099777
si:dkey-103i16.6
si:dkey-103i16.6
chr3_-_26191960 1.05 ENSDART00000113843
ypel3
yippee-like 3
chr23_-_24226533 1.04 ENSDART00000109134
plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr5_+_22579975 1.03 ENSDART00000080877
tnfsf10l4
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr11_+_2710530 0.94 ENSDART00000132768
ENSDART00000030921
ENSDART00000040147
mapk14b
mitogen-activated protein kinase 14b
chr17_+_14965570 0.93 ENSDART00000066604
gpr137c
G protein-coupled receptor 137c
chr25_+_7494181 0.82 ENSDART00000165005
cat
catalase
chr15_+_23657051 0.81 ENSDART00000078336
klc3
kinesin light chain 3
chr14_+_32926385 0.79 ENSDART00000139159
lnx2b
ligand of numb-protein X 2b
chr13_+_29925397 0.79 ENSDART00000123482
cuedc2
CUE domain containing 2
chr1_+_45969240 0.73 ENSDART00000042086
arhgef7b
Rho guanine nucleotide exchange factor (GEF) 7b
chr19_+_31585341 0.72 ENSDART00000052185
gmnn
geminin, DNA replication inhibitor
chr3_+_53116172 0.69 ENSDART00000115117
brd4
bromodomain containing 4
chr14_+_35424539 0.68 ENSDART00000171809
ENSDART00000162185
sytl4
synaptotagmin-like 4
chr14_+_15155684 0.68 ENSDART00000167966
zgc:158852
zgc:158852
chr23_+_28377360 0.66 ENSDART00000014983
ENSDART00000128831
ENSDART00000135178
ENSDART00000138621
zgc:153867
zgc:153867
chr11_+_18873619 0.64 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr3_+_54168007 0.63 ENSDART00000109894
olfm2a
olfactomedin 2a
chr7_-_51749683 0.63 ENSDART00000083190
hdac8
histone deacetylase 8
chr9_+_24088062 0.62 ENSDART00000126198
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr17_-_9962578 0.61 ENSDART00000021942
eapp
e2f-associated phosphoprotein
chr16_-_32671998 0.59 ENSDART00000161395
pnisr
PNN-interacting serine/arginine-rich protein
chr4_-_16876281 0.58 ENSDART00000016690
ENSDART00000044005
ENSDART00000042874
ENSDART00000125762
ENSDART00000185974
tmpoa
thymopoietin a
chr13_+_29926094 0.57 ENSDART00000057528
cuedc2
CUE domain containing 2
chr24_-_25144441 0.57 ENSDART00000152104
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr7_+_24023653 0.57 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr5_+_28271412 0.56 ENSDART00000031727
vamp8
vesicle-associated membrane protein 8 (endobrevin)
chr15_+_19990068 0.55 ENSDART00000154033
ENSDART00000054428
zgc:112083
zgc:112083
chr20_-_25643667 0.55 ENSDART00000137457
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr8_+_21225064 0.54 ENSDART00000129210
cry1ba
cryptochrome circadian clock 1ba
chr2_-_32262287 0.53 ENSDART00000056621
ENSDART00000039717
fam49ba
family with sequence similarity 49, member Ba
chr24_-_25004553 0.53 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr17_-_14966384 0.53 ENSDART00000105064
txndc16
thioredoxin domain containing 16
chr16_-_32671782 0.52 ENSDART00000123980
pnisr
PNN-interacting serine/arginine-rich protein
chr16_-_47381519 0.52 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
si:dkey-256h2.1
chr19_-_12965020 0.51 ENSDART00000128975
slc25a32a
solute carrier family 25 (mitochondrial folate carrier), member 32a
chr11_+_18612421 0.51 ENSDART00000110621
ncoa3
nuclear receptor coactivator 3
chr10_-_6588793 0.51 ENSDART00000163788
chd1
chromodomain helicase DNA binding protein 1
chr22_-_4769140 0.50 ENSDART00000165235
calr3a
calreticulin 3a
chr10_-_15879569 0.49 ENSDART00000136789
tjp2a
tight junction protein 2a (zona occludens 2)
chr15_-_44052927 0.48 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr2_-_17492486 0.47 ENSDART00000189464
kdm4ab
lysine (K)-specific demethylase 4A, genome duplicate b
chr6_-_12172424 0.47 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr10_-_36633882 0.47 ENSDART00000077161
ENSDART00000137688
rsf1b.1
rsf1b.1
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr3_-_13546610 0.47 ENSDART00000159647
amdhd2
amidohydrolase domain containing 2
chr20_-_35470891 0.46 ENSDART00000152993
ENSDART00000016090
pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr10_+_42589707 0.45 ENSDART00000075269
fgfr1b
fibroblast growth factor receptor 1b
chr20_+_25904199 0.45 ENSDART00000016864
slc35f6
solute carrier family 35, member F6
chr13_-_50247689 0.45 ENSDART00000034541
gpatch11
G patch domain containing 11
chr18_-_40913294 0.45 ENSDART00000059196
ENSDART00000098878
polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr12_-_48188928 0.44 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr8_+_16676894 0.43 ENSDART00000076586
si:ch211-198n5.11
si:ch211-198n5.11
chr13_+_1100197 0.43 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr5_-_69212184 0.42 ENSDART00000053963
mat2ab
methionine adenosyltransferase II, alpha b
chr20_-_52928541 0.42 ENSDART00000162812
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr8_-_25716074 0.40 ENSDART00000007482
tspy
testis specific protein, Y-linked
chr24_-_18659147 0.40 ENSDART00000166039
zgc:66014
zgc:66014
chr8_+_10823069 0.40 ENSDART00000081341
mapk13
mitogen-activated protein kinase 13
chr6_-_40922971 0.38 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr12_+_8822717 0.37 ENSDART00000021628
reep3b
receptor accessory protein 3b
chr3_-_4501026 0.37 ENSDART00000163052
zgc:162198
zgc:162198
chr10_+_42589391 0.37 ENSDART00000067689
ENSDART00000075259
fgfr1b
fibroblast growth factor receptor 1b
chr7_-_13906409 0.37 ENSDART00000062257
slc39a1
solute carrier family 39 (zinc transporter), member 1
chr23_+_22785375 0.36 ENSDART00000142085
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr8_+_26396552 0.36 ENSDART00000087151
amt
aminomethyltransferase
chr6_-_32045951 0.36 ENSDART00000016629
ENSDART00000139055
efcab7
EF-hand calcium binding domain 7
chr13_+_5978809 0.35 ENSDART00000102563
ENSDART00000121598
phf10
PHD finger protein 10
chr5_-_51998708 0.35 ENSDART00000097194
serinc5
serine incorporator 5
chr18_+_1703984 0.35 ENSDART00000114010
slitrk3a
SLIT and NTRK-like family, member 3a
chr2_-_17492080 0.35 ENSDART00000024302
kdm4ab
lysine (K)-specific demethylase 4A, genome duplicate b
chr19_-_12967986 0.33 ENSDART00000151064
slc25a32a
solute carrier family 25 (mitochondrial folate carrier), member 32a
chr2_+_25839650 0.32 ENSDART00000134077
ENSDART00000140804
eif5a2
eukaryotic translation initiation factor 5A2
chr2_+_25839940 0.32 ENSDART00000139927
eif5a2
eukaryotic translation initiation factor 5A2
chr16_+_36748538 0.32 ENSDART00000139069
decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr3_+_27786601 0.32 ENSDART00000086994
nat15
N-acetyltransferase 15 (GCN5-related, putative)
chr9_-_12885201 0.32 ENSDART00000124957
ankzf1
ankyrin repeat and zinc finger domain containing 1
chr5_-_8682590 0.31 ENSDART00000142762
zgc:153352
zgc:153352
chr2_-_47957673 0.31 ENSDART00000056305
fzd8b
frizzled class receptor 8b
chr24_+_14240196 0.30 ENSDART00000124740
ncoa2
nuclear receptor coactivator 2
chr5_+_53009083 0.30 ENSDART00000157836
hint2
histidine triad nucleotide binding protein 2
chr5_+_15495351 0.30 ENSDART00000111646
ENSDART00000114446
suds3
SDS3 homolog, SIN3A corepressor complex component
chr7_+_26049818 0.30 ENSDART00000173611
si:dkey-6n21.12
si:dkey-6n21.12
chr12_+_8569685 0.30 ENSDART00000031676
nrbf2b
nuclear receptor binding factor 2b
chr6_-_39919982 0.30 ENSDART00000065091
ENSDART00000064903
sumf1
sulfatase modifying factor 1
chr23_-_33680265 0.29 ENSDART00000138416
tfcp2
transcription factor CP2
chr23_-_17450746 0.28 ENSDART00000145399
ENSDART00000136457
ENSDART00000133125
ENSDART00000145719
ENSDART00000147524
ENSDART00000005366
ENSDART00000104680
tpd52l2b
tumor protein D52-like 2b
chr21_-_13662237 0.28 ENSDART00000091647
ENSDART00000151547
pnpla7a
patatin-like phospholipase domain containing 7a
chr13_-_31017960 0.27 ENSDART00000145287
wdfy4
WDFY family member 4
chr15_-_28805493 0.25 ENSDART00000179617
cd3eap
CD3e molecule, epsilon associated protein
chr13_+_42602406 0.25 ENSDART00000133388
ENSDART00000147996
mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
chr19_-_10323845 0.24 ENSDART00000151259
ENSDART00000151821
u2af2b
U2 small nuclear RNA auxiliary factor 2b
chr19_-_10324182 0.24 ENSDART00000151352
ENSDART00000151162
ENSDART00000023571
u2af2b
U2 small nuclear RNA auxiliary factor 2b
chr1_-_9277986 0.23 ENSDART00000146065
ENSDART00000114876
ENSDART00000132812
ubn1
ubinuclein 1
chr4_-_17353972 0.23 ENSDART00000041529
parpbp
PARP1 binding protein
chr7_-_28611145 0.23 ENSDART00000054366
scube2
signal peptide, CUB domain, EGF-like 2
chr16_-_44900306 0.22 ENSDART00000058380
rbm42
RNA binding motif protein 42
chr8_+_7778770 0.22 ENSDART00000171325
tfe3a
transcription factor binding to IGHM enhancer 3a
chr9_+_17971935 0.21 ENSDART00000149736
akap11
A kinase (PRKA) anchor protein 11
chr15_-_25527580 0.20 ENSDART00000167005
ENSDART00000157498
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr3_+_42999844 0.20 ENSDART00000183950
ints1
integrator complex subunit 1
chr12_-_35105670 0.19 ENSDART00000153034
si:ch73-127m5.2
si:ch73-127m5.2
chr23_-_12158685 0.19 ENSDART00000135035
fam217b
family with sequence similarity 217, member B
chr3_+_42999277 0.19 ENSDART00000163595
ints1
integrator complex subunit 1
chr7_+_38278860 0.19 ENSDART00000016265
lrp3
low density lipoprotein receptor-related protein 3
chr7_+_46003449 0.19 ENSDART00000159700
ENSDART00000173625
si:ch211-260e23.9
si:ch211-260e23.9
chr8_+_17869225 0.18 ENSDART00000080079
slc44a5b
solute carrier family 44, member 5b
chr15_+_30157602 0.17 ENSDART00000047248
ENSDART00000123937
nlk2
nemo-like kinase, type 2
chr15_-_17010358 0.16 ENSDART00000156768
hip1
huntingtin interacting protein 1
chr9_+_23900703 0.16 ENSDART00000127859
trim63b
tripartite motif containing 63b
chr10_-_8197049 0.14 ENSDART00000129467
dhx29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr20_-_9428021 0.13 ENSDART00000025330
rdh14b
retinol dehydrogenase 14b
chr1_-_28749604 0.13 ENSDART00000148522
GK3P
zgc:172295
chr25_+_27405738 0.13 ENSDART00000183266
ENSDART00000115139
pot1
protection of telomeres 1 homolog
chr5_-_38384289 0.13 ENSDART00000135260
mink1
misshapen-like kinase 1
chr24_+_17007407 0.12 ENSDART00000110652
zfx
zinc finger protein, X-linked
chr8_+_26432677 0.11 ENSDART00000078369
ENSDART00000131925
zgc:136971
zgc:136971
chr8_+_37749263 0.11 ENSDART00000108556
ENSDART00000147942
npm2a
nucleophosmin/nucleoplasmin, 2a
chr1_+_45839927 0.10 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
map2k7
mitogen-activated protein kinase kinase 7
chr9_-_16876474 0.09 ENSDART00000185450
fbxl3a
F-box and leucine-rich repeat protein 3a
chr16_+_49647402 0.08 ENSDART00000015694
ENSDART00000132547
rab5ab
RAB5A, member RAS oncogene family, b
chr18_-_14337450 0.08 ENSDART00000061435
hsbp1b
heat shock factor binding protein 1b
chr6_+_42475730 0.08 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr9_-_16877456 0.06 ENSDART00000161105
ENSDART00000160869
fbxl3a
F-box and leucine-rich repeat protein 3a
chr15_+_8043751 0.06 ENSDART00000193701
cadm2b
cell adhesion molecule 2b
chr20_-_9980318 0.05 ENSDART00000080664
ACTC1
zgc:86709
chr15_-_31498123 0.05 ENSDART00000153665
si:dkey-1m11.6
si:dkey-1m11.6
chr8_-_4031121 0.05 ENSDART00000169474
ENSDART00000163754
mtmr3
myotubularin related protein 3
chr17_+_44756247 0.04 ENSDART00000153773
cipca
CLOCK-interacting pacemaker a
chr19_+_12237945 0.04 ENSDART00000190034
grhl2b
grainyhead-like transcription factor 2b
chr3_-_31057624 0.04 ENSDART00000152901
armc5
armadillo repeat containing 5
chr5_+_24063046 0.03 ENSDART00000051548
ENSDART00000133355
ENSDART00000142268
gps2
G protein pathway suppressor 2
chr10_-_36225729 0.03 ENSDART00000127677
or109-5
odorant receptor, family D, subfamily 109, member 5
chr6_+_39279831 0.03 ENSDART00000155088
ankrd33ab
ankyrin repeat domain 33Ab
chr17_-_2690083 0.02 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr1_+_9966384 0.02 ENSDART00000132607
si:dkeyp-75b4.8
si:dkeyp-75b4.8
chr2_-_25553607 0.02 ENSDART00000150075
ENSDART00000078695
ghsra
growth hormone secretagogue receptor a
chr20_-_211920 0.02 ENSDART00000104790
znf292b
zinc finger protein 292b
chr7_+_72279584 0.02 ENSDART00000172021
tollip
toll interacting protein
chr10_-_9089545 0.02 ENSDART00000080781
arl15b
ADP-ribosylation factor-like 15b
chr21_+_32338897 0.02 ENSDART00000110137
si:ch211-247j9.1
si:ch211-247j9.1
chr4_+_17353714 0.01 ENSDART00000136299
nup37
nucleoporin 37
chr2_+_44615153 0.01 ENSDART00000156523
yeats2
YEATS domain containing 2
chr15_+_16897554 0.01 ENSDART00000154679
ypel2b
yippee-like 2b
chr15_+_20543770 0.01 ENSDART00000092357
sgsm2
small G protein signaling modulator 2
chr22_-_7129631 0.01 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr16_+_25011994 0.01 ENSDART00000157312
znf1035
zinc finger protein 1035
chr17_-_15746898 0.01 ENSDART00000180079
cx52.7
connexin 52.7
chr18_+_27000850 0.00 ENSDART00000188906
ENSDART00000086131
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr10_-_36214582 0.00 ENSDART00000166471
or109-11
odorant receptor, family D, subfamily 109, member 11
chr6_-_9565526 0.00 ENSDART00000151470
map3k2
mitogen-activated protein kinase kinase kinase 2
chr18_-_26675699 0.00 ENSDART00000113280
FRMD5
si:ch211-69m14.1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo3a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.5 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 0.6 GO:0070254 mucus secretion(GO:0070254)
0.1 1.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.6 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 1.0 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.1 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.9 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.7 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.8 GO:0046688 response to copper ion(GO:0046688)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.7 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.5 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.2 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.5 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.0 GO:0042754 negative regulation of circadian rhythm(GO:0042754)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.6 GO:0070187 telosome(GO:0070187)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.7 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.3 0.8 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.8 GO:0004096 catalase activity(GO:0004096)
0.1 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.8 GO:0004407 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
0.1 0.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription