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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxm1

Z-value: 0.42

Motif logo

Transcription factors associated with foxm1

Gene Symbol Gene ID Gene Info
ENSDARG00000003200 forkhead box M1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxm1dr11_v1_chr4_-_5831522_58315220.753.5e-04Click!

Activity profile of foxm1 motif

Sorted Z-values of foxm1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_30039331 1.36 ENSDART00000086935
ENSDART00000143800
zgc:153256
chr14_-_52480661 0.87 ENSDART00000158353
exosome component 3
chr12_-_2993095 0.79 ENSDART00000152316
si:dkey-202c14.3
chr7_+_24115082 0.70 ENSDART00000182718
mitochondrial ribosomal protein L52
chr16_+_2433696 0.63 ENSDART00000182803

chr19_+_31904836 0.63 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tumor protein D52
chr5_-_13251907 0.60 ENSDART00000176774
ENSDART00000030553
DNA topoisomerase III beta
chr20_-_39596338 0.59 ENSDART00000023531
hes-related family bHLH transcription factor with YRPW motif 2
chr19_+_43604643 0.58 ENSDART00000151168
si:ch211-199g17.9
chr2_-_32505091 0.58 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr7_+_24114694 0.57 ENSDART00000127177
mitochondrial ribosomal protein L52
chr19_+_11978209 0.57 ENSDART00000111568
polymerase (RNA) II (DNA directed) polypeptide K
chr19_+_43604256 0.56 ENSDART00000151080
ENSDART00000110305
si:ch211-199g17.9
chr10_-_26512742 0.55 ENSDART00000135951
si:dkey-5g14.1
chr14_+_45565891 0.55 ENSDART00000133389
ENSDART00000025549
zgc:92249
chr7_-_41554047 0.54 ENSDART00000174144
plexin domain containing 2
chr20_-_22798794 0.53 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr4_-_6809323 0.52 ENSDART00000099467
interferon-related developmental regulator 1
chr5_-_54672763 0.51 ENSDART00000159009
sperm associated antigen 8
chr3_-_13461056 0.45 ENSDART00000137678
F-box and WD repeat domain containing 9
chr6_+_16949735 0.44 ENSDART00000155342
Pim proto-oncogene, serine/threonine kinase, related 13
chr11_+_2416064 0.44 ENSDART00000067117
ubiquitin-conjugating enzyme E2 variant 1
chr15_+_23784842 0.44 ENSDART00000192889
ENSDART00000138375
intraflagellar transport 20 homolog (Chlamydomonas)
chr22_+_31059919 0.44 ENSDART00000077063
SEC13 homolog, nuclear pore and COPII coat complex component
chr25_+_27873836 0.44 ENSDART00000163801
IQ motif and ubiquitin domain containing
chr5_-_68826177 0.43 ENSDART00000136605
si:ch211-283h6.4
chr15_-_47822597 0.43 ENSDART00000193236
ENSDART00000161391

chr8_+_40210398 0.43 ENSDART00000167612
ring finger protein 34a
chr7_+_52766211 0.42 ENSDART00000186191
diphosphoinositol pentakisphosphate kinase 1a
chr16_-_24194587 0.42 ENSDART00000181520
ribosomal protein S19
chr8_+_17987215 0.42 ENSDART00000113605
leucine-rich repeats and IQ motif containing 3
chr15_-_23692359 0.41 ENSDART00000141618
excision repair cross-complementation group 2
chr3_-_16068236 0.41 ENSDART00000157315
si:dkey-81l17.6
chr13_+_24679674 0.41 ENSDART00000033090
ENSDART00000139854
zgc:66426
chr17_+_46818521 0.41 ENSDART00000156022
Pim proto-oncogene, serine/threonine kinase, related 14
chr7_+_26629084 0.40 ENSDART00000101044
ENSDART00000173765
heat shock factor binding protein 1a
chr8_+_50531709 0.40 ENSDART00000193352
phosphatidylethanolamine binding protein 4
chr21_-_3796461 0.40 ENSDART00000021976
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr25_+_27873671 0.39 ENSDART00000088817
IQ motif and ubiquitin domain containing
chr6_-_16894312 0.39 ENSDART00000155450
Pim proto-oncogene, serine/threonine kinase, related 42
chr25_+_36045072 0.38 ENSDART00000126326
RPGRIP1-like
chr20_-_14925281 0.38 ENSDART00000152641
dynamin 3a
chr5_+_34982318 0.37 ENSDART00000160504
ankyrin repeat, family A (RFXANK-like), 2
chr4_-_6567355 0.37 ENSDART00000134820
ENSDART00000142087
forkhead box P2
chr1_+_38362412 0.37 ENSDART00000075086
centrosomal protein 44
chr4_-_75157223 0.36 ENSDART00000174127

chr3_+_37112693 0.36 ENSDART00000055228
ENSDART00000144278
ENSDART00000138079
PSMC3 interacting protein
chr14_-_33454595 0.36 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr24_+_5840258 0.36 ENSDART00000087034
transient receptor potential cation channel, subfamily C, member 1
chr7_-_51102479 0.36 ENSDART00000174023
collagen, type IV, alpha 6
chr4_-_17725008 0.35 ENSDART00000016658
choline phosphotransferase 1
chr20_+_30939178 0.35 ENSDART00000062556
superoxide dismutase 2, mitochondrial
chr14_-_4177311 0.34 ENSDART00000128129
si:dkey-185e18.7
chr17_+_10593398 0.33 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mitogen-activated protein kinase binding protein 1
chr19_+_233143 0.33 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr2_+_22694382 0.32 ENSDART00000139196
kinesin family member 1Ab
chr10_-_35051691 0.31 ENSDART00000108670
ENSDART00000190711
SPT20 homolog, SAGA complex component
chr2_+_17540720 0.31 ENSDART00000114638
Pim proto-oncogene, serine/threonine kinase, related 198
chr6_-_16735402 0.31 ENSDART00000154216
Pim proto-oncogene, serine/threonine kinase, related 44
chr7_+_39401388 0.31 ENSDART00000144750
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr14_-_44790817 0.31 ENSDART00000098640
glyoxylate reductase/hydroxypyruvate reductase a
chr21_+_13182149 0.31 ENSDART00000140267
spectrin alpha, non-erythrocytic 1
chr17_+_46935061 0.31 ENSDART00000156578
Pim proto-oncogene, serine/threonine kinase, related 26
chr16_-_50203058 0.30 ENSDART00000154570
V-set and immunoglobulin domain containing 10 like
chr23_+_13928346 0.30 ENSDART00000155326
si:dkey-90a13.10
chr10_+_35554219 0.30 ENSDART00000077373
zinc finger, DHHC-type containing 20a
chr15_+_37589698 0.29 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin-37 DREAM MuvB core complex component
chr13_+_12761707 0.29 ENSDART00000015127
zgc:100846
chr20_+_16881883 0.29 ENSDART00000130107
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr10_-_35052198 0.29 ENSDART00000147805
SPT20 homolog, SAGA complex component
chr22_-_17606575 0.29 ENSDART00000183951
glutathione peroxidase 4a
chr12_-_48566778 0.28 ENSDART00000063442
cytochrome P450, family 4, subfamily F, polypeptide 3
chr5_-_64883082 0.28 ENSDART00000064983
ENSDART00000139066
keratin, type 1, gene c5
chr3_-_13461361 0.28 ENSDART00000080807
F-box and WD repeat domain containing 9
chr12_+_30234209 0.28 ENSDART00000102081
actin filament associated protein 1-like 2
chr11_-_22369303 0.28 ENSDART00000163450
transmembrane protein 183A
chr11_+_6881001 0.28 ENSDART00000170331
kelch-like family member 26
chr5_+_34981584 0.27 ENSDART00000134795
ankyrin repeat, family A (RFXANK-like), 2
chr2_-_10338759 0.27 ENSDART00000150166
ENSDART00000149584
guanine nucleotide binding protein (G protein), gamma 12a
chr10_+_19017146 0.26 ENSDART00000038674
transmembrane protein 230a
chr20_+_9124369 0.26 ENSDART00000064150
si:ch211-59d15.9
chr3_-_37758487 0.26 ENSDART00000150938
si:dkey-260c8.6
chr9_-_38368138 0.26 ENSDART00000059574
coiled-coil domain containing 93
chr3_+_5575313 0.26 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
chr22_+_2315996 0.26 ENSDART00000132489
zinc finger protein 1175
chr7_+_30282389 0.26 ENSDART00000108782
RNA polymerase II subunit M
chr2_+_17524278 0.25 ENSDART00000165633
Pim proto-oncogene, serine/threonine kinase, related 196
chr22_-_9934854 0.25 ENSDART00000136404
si:dkey-253d23.11
chr7_+_17255705 0.25 ENSDART00000053357
ENSDART00000167849
ENSDART00000165833
novel immune-type receptor 9
si:ch73-46n24.1
chr9_-_31108285 0.25 ENSDART00000003193
G protein-coupled receptor 183a
chr11_-_1509773 0.24 ENSDART00000050762
phosphatase and actin regulator 3b
chr6_-_29288155 0.24 ENSDART00000078630
NME/NM23 family member 7
chr2_+_3595333 0.24 ENSDART00000041052
complement component 1, q subcomponent-like 3b
chr17_+_43890736 0.24 ENSDART00000179918
mutS homolog 4
chr4_-_890220 0.24 ENSDART00000022668
crystallin beta-gamma domain containing 1b
chr5_-_67757188 0.24 ENSDART00000167168
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr14_-_8453192 0.23 ENSDART00000136947
eukaryotic translation initiation factor 1A domain containing
chr21_-_25565392 0.23 ENSDART00000144917
ENSDART00000180102
si:dkey-17e16.10
chr12_-_9516981 0.23 ENSDART00000106285
si:ch211-207i20.3
chr8_+_7033049 0.23 ENSDART00000064172
ENSDART00000134440
glycerol-3-phosphate dehydrogenase 1a
chr2_-_22688651 0.23 ENSDART00000013863
alanine-glyoxylate aminotransferase b
chr14_+_23687678 0.22 ENSDART00000002469
heat shock protein 4b
chr11_-_28614608 0.22 ENSDART00000065853
dehydrogenase/reductase (SDR family) member 3b
chr17_-_46933567 0.22 ENSDART00000157274
Pim proto-oncogene, serine/threonine kinase, related 25
chr14_+_45559268 0.22 ENSDART00000173152
zgc:154040
chr6_+_16870004 0.21 ENSDART00000154794
Pim proto-oncogene, serine/threonine kinase, related 21
chr6_+_18569453 0.21 ENSDART00000171338
ras homolog family member T1
chr2_+_3986083 0.21 ENSDART00000188979
mohawk homeobox b
chr4_-_22472653 0.21 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
lysine (K)-specific methyltransferase 2E
chr18_-_15932704 0.21 ENSDART00000127769
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr11_-_24347644 0.21 ENSDART00000089777
si:ch211-15p9.2
chr7_+_26716321 0.20 ENSDART00000189750
CD82 molecule a
chr25_-_35045250 0.20 ENSDART00000156508
ENSDART00000126590
zgc:114046
chr5_-_24333684 0.20 ENSDART00000051553
zinc finger protein 703
chr18_-_16795262 0.20 ENSDART00000048722
adenosine monophosphate deaminase 3b
chr22_+_1421212 0.20 ENSDART00000161813
zgc:101130
chr4_+_25558849 0.19 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
chr5_-_16351306 0.19 ENSDART00000168643

chr11_+_11201096 0.19 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr23_-_40817792 0.19 ENSDART00000136343
si:dkeyp-27c8.1
chr23_+_39611688 0.19 ENSDART00000034690
OTU deubiquitinase 3
chr13_+_13770980 0.18 ENSDART00000113089
solute carrier family 4, sodium borate transporter, member 11
chr16_-_53800047 0.18 ENSDART00000158047
zinc and ring finger 2b
chr5_-_16475682 0.18 ENSDART00000090695
piwi-like RNA-mediated gene silencing 2
chr4_-_18436899 0.18 ENSDART00000141671
suppressor of cytokine signaling 2
chr9_+_23770666 0.18 ENSDART00000182493
si:ch211-219a4.3
chr4_-_12388535 0.18 ENSDART00000017180
RERG/RAS-like a
chr18_+_19120984 0.18 ENSDART00000141501
si:dkey-242h9.3
chr12_+_9542124 0.17 ENSDART00000127952
prolyl 4-hydroxylase, alpha polypeptide I a
chr11_-_33618612 0.17 ENSDART00000033980
LIM and senescent cell antigen-like domains 1
chr19_+_7759354 0.17 ENSDART00000151400
ubiquitin associated protein 2-like
chr23_+_25305431 0.17 ENSDART00000143291
si:dkey-151g10.6
chr19_+_18627100 0.17 ENSDART00000167245
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr10_+_35257651 0.17 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr18_-_37407235 0.17 ENSDART00000132315
centrosomal protein 126
chr7_+_10592152 0.17 ENSDART00000182624
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr7_+_13995792 0.17 ENSDART00000091470
furin (paired basic amino acid cleaving enzyme) a
chr4_-_39111612 0.17 ENSDART00000150394
si:dkey-122c11.8
chr2_-_29761965 0.17 ENSDART00000142057
ENSDART00000110595
si:dkey-188g12.1
chr4_-_23759192 0.16 ENSDART00000014685
ENSDART00000131690
carboxypeptidase M
chr15_+_3674765 0.16 ENSDART00000081802
NIMA related kinase 3
chr6_+_17113677 0.16 ENSDART00000154080
Pim proto-oncogene, serine/threonine kinase, related 5
chr2_+_31476065 0.16 ENSDART00000049219
calcium channel, voltage-dependent, beta 2b
chr15_-_23784600 0.16 ENSDART00000059354
RAD1 homolog (S. pombe)
chr8_-_37056622 0.16 ENSDART00000111513
si:ch211-218o21.4
chr16_+_53125918 0.16 ENSDART00000102170

chr20_-_26383368 0.16 ENSDART00000024518
ENSDART00000087844
estrogen receptor 1
chr5_+_26079178 0.16 ENSDART00000145920
si:dkey-201c13.2
chr2_-_37837472 0.16 ENSDART00000165347
methyltransferase like 17
chr17_-_53440284 0.16 ENSDART00000126976
c-myc binding protein
chr22_+_1734981 0.16 ENSDART00000158195
zinc finger protein 1159
chr14_+_52481288 0.15 ENSDART00000169164
ENSDART00000159297
transcription elongation regulator 1a (CA150)
chr15_-_28082310 0.15 ENSDART00000152620
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr24_-_17444067 0.15 ENSDART00000155843
contactin associated protein like 2a
chr6_+_17181157 0.15 ENSDART00000154962
Pim proto-oncogene, serine/threonine kinase, related 4
chr21_+_13353263 0.15 ENSDART00000114677
si:ch73-62l21.1
chr4_-_73787702 0.14 ENSDART00000136328
ENSDART00000150546
si:dkey-262g12.3
chr6_-_23931442 0.14 ENSDART00000160547
SEC16 homolog B, endoplasmic reticulum export factor
chr11_+_6422374 0.14 ENSDART00000183148

chr13_-_280827 0.14 ENSDART00000144819
solute carrier family 30 (zinc transporter), member 6
chr20_+_38525567 0.14 ENSDART00000147787
zinc finger protein 512
chr6_-_16948040 0.13 ENSDART00000156433
Pim proto-oncogene, serine/threonine kinase, related 30
chr5_+_50898849 0.13 ENSDART00000083317
arylsulfatase family, member K
chr7_+_38811800 0.13 ENSDART00000052322
zgc:110699
chr9_+_2522797 0.13 ENSDART00000186786
ENSDART00000147034
G protein-coupled receptor 155a
chr17_-_53439866 0.13 ENSDART00000154826
c-myc binding protein
chr14_+_31865099 0.13 ENSDART00000189124
transmembrane 9 superfamily protein member 5
chr14_+_8343498 0.13 ENSDART00000164551
neuregulin 2b
chr11_+_44502410 0.12 ENSDART00000172998
endoplasmic reticulum oxidoreductase beta
chr16_-_55028740 0.12 ENSDART00000156368
ENSDART00000161704
zgc:114181
chr6_+_16736871 0.12 ENSDART00000155471
Pim proto-oncogene, serine/threonine kinase, related 12
chr6_-_16804001 0.12 ENSDART00000155398
Pim proto-oncogene, serine/threonine kinase, related 40
chr14_+_22498757 0.12 ENSDART00000021657
SMYD family member 5
chr8_+_32719930 0.12 ENSDART00000145362
hemicentin 2
chr14_-_26177156 0.12 ENSDART00000014149
FAT atypical cadherin 2
chr11_-_42418374 0.12 ENSDART00000160704
sarcolemma associated protein a
chr6_+_35362225 0.11 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr1_-_23268013 0.11 ENSDART00000146575
replication factor C (activator 1) 1
chr19_-_18626952 0.11 ENSDART00000168004
ENSDART00000162034
ENSDART00000165486
ENSDART00000167971
ribosomal protein S18
chr7_-_50604626 0.11 ENSDART00000073903
ENSDART00000174031
CREB regulated transcription coactivator 3
chr5_-_38197080 0.11 ENSDART00000140708
si:ch211-284e13.9
chr24_-_2312868 0.11 ENSDART00000140125
ENSDART00000138432
cullin 2
chr21_+_3796620 0.11 ENSDART00000099535
ENSDART00000144515
SPOUT domain containing methyltransferase 1
chr4_-_68913650 0.10 ENSDART00000184297
si:dkey-264f17.5
chr7_-_20836625 0.10 ENSDART00000192566
claudin 15a
chr15_-_23761580 0.10 ENSDART00000137918
BCL2 binding component 3
chr9_-_38036984 0.10 ENSDART00000134574
3-hydroxyacyl-CoA dehydratase 2
chr22_+_2254972 0.10 ENSDART00000144906
zinc finger protein 1157
chr6_+_17267681 0.10 ENSDART00000156312
Pim proto-oncogene, serine/threonine kinase, related 15
chr25_+_28679672 0.10 ENSDART00000139965
ENSDART00000134072
CCR4-NOT transcription complex, subunit 2
chr20_-_39273987 0.09 ENSDART00000127173
clusterin
chr25_+_4812685 0.09 ENSDART00000193103
myosin VC
chr19_-_27261102 0.09 ENSDART00000143919
gamma-aminobutyric acid (GABA) B receptor, 1b
chr1_+_55535827 0.09 ENSDART00000152784
adhesion G protein-coupled receptor E16
chr22_-_29205327 0.09 ENSDART00000183161
ENSDART00000189515
parvalbumin 7
chr11_-_25213651 0.09 ENSDART00000097316
ENSDART00000152186
myosin, heavy chain 7B, cardiac muscle, beta a
chr8_+_8973425 0.09 ENSDART00000066107
B cell receptor associated protein 31
chr7_+_1505507 0.09 ENSDART00000161015
NOP10 ribonucleoprotein homolog (yeast)
chr7_+_60359347 0.09 ENSDART00000145201
ENSDART00000039827
protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
chr12_+_19191787 0.09 ENSDART00000152892
solute carrier family 16 (monocarboxylate transporter), member 8

Network of associatons between targets according to the STRING database.

First level regulatory network of foxm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0071034 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2 0.6 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.1 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.4 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.1 0.3 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.1 0.3 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 0.2 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 1.1 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 0.4 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.2 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.4 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.1 0.2 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 0.4 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.3 GO:0036268 swimming(GO:0036268)
0.0 0.2 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.4 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.6 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.6 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 1.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.4 GO:0045471 response to ethanol(GO:0045471)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.4 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0090497 skin morphogenesis(GO:0043589) mesenchymal cell migration(GO:0090497)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.1 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 3.6 GO:0046777 protein autophosphorylation(GO:0046777)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.9 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.4 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 1.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0005948 acetolactate synthase complex(GO:0005948)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.8 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.2 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0003984 acetolactate synthase activity(GO:0003984)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0008378 galactosyltransferase activity(GO:0008378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex