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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxl1

Z-value: 1.24

Motif logo

Transcription factors associated with foxl1

Gene Symbol Gene ID Gene Info
ENSDARG00000008133 forkhead box L1
ENSDARG00000111418 forkhead box L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxl1dr11_v1_chr18_-_17485419_17485419-0.981.0e-12Click!

Activity profile of foxl1 motif

Sorted Z-values of foxl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_19719240 4.84 ENSDART00000135405
cysteine-serine-rich nuclear protein 1b
chr15_-_37104165 3.72 ENSDART00000165867
zmp:0000001114
chr7_-_71585065 3.55 ENSDART00000128678
methyltransferase like 4
chr7_+_58751504 3.16 ENSDART00000024185
zgc:56231
chr20_+_22799641 2.96 ENSDART00000131132
sec1 family domain containing 2
chr19_-_11315224 2.88 ENSDART00000104933
endonuclease/exonuclease/phosphatase family domain containing 1
chr12_-_1034383 2.81 ENSDART00000152455
ENSDART00000152346
polymerase (RNA) III (DNA directed) polypeptide E
chr11_-_10456553 2.67 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
epithelial cell transforming 2
chr20_+_22799857 2.63 ENSDART00000058527
sec1 family domain containing 2
chr20_-_52882881 2.53 ENSDART00000111078
wu:fi04e12
chr15_+_34946779 2.36 ENSDART00000192661
ENSDART00000188800
ENSDART00000156515
si:ch73-95l15.5
zgc:55621
chr8_-_22514918 2.34 ENSDART00000021514
ENSDART00000189272
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr16_+_30002605 2.34 ENSDART00000160555
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr2_+_37245382 2.33 ENSDART00000004626
SEC62 homolog, preprotein translocation factor
chr24_-_21090447 2.33 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
queuine tRNA-ribosyltransferase accessory subunit 2
chr12_-_48188928 2.30 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr24_-_26632171 2.30 ENSDART00000008374
ENSDART00000017384
TRAF2 and NCK interacting kinase b
chr21_+_3244146 2.26 ENSDART00000127740
CBP80/20-dependent translation initiation factor
chr17_+_25331576 2.21 ENSDART00000157309
transmembrane protein 54a
chr13_-_24260609 2.21 ENSDART00000138747
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr12_-_34827477 2.18 ENSDART00000153026
si:dkey-21c1.6
chr6_+_33931740 2.12 ENSDART00000130492
ENSDART00000151213
origin recognition complex, subunit 1
chr3_-_20118342 2.12 ENSDART00000139902
selenoprotein W, 2a
chr10_+_23060391 2.11 ENSDART00000079711
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr3_+_30190419 2.10 ENSDART00000157320
AKT1 substrate 1 (proline-rich)
chr21_-_30168947 2.07 ENSDART00000130820
ENSDART00000193171
heparin-binding EGF-like growth factor b
chr14_+_31618982 2.05 ENSDART00000026195
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr11_-_44979281 2.03 ENSDART00000190972
LIM-domain binding 1b
chr9_+_29520696 2.02 ENSDART00000144430
ferredoxin 1
chr9_-_37367477 1.95 ENSDART00000182711
ENSDART00000192655
hspb associated protein 1
chr3_-_12227359 1.95 ENSDART00000167356
transcription factor AP-4 (activating enhancer binding protein 4)
chr1_+_496268 1.93 ENSDART00000109415
basic leucine zipper nuclear factor 1
chr10_-_21362320 1.92 ENSDART00000189789
avidin
chr10_+_39199547 1.90 ENSDART00000075943
etoposide induced 2.4
chr5_+_37379825 1.89 ENSDART00000171826
kelch-like family member 13
chr13_+_49727333 1.85 ENSDART00000168799
ENSDART00000037559
geranylgeranyl diphosphate synthase 1
chr15_+_28175638 1.85 ENSDART00000037119
solute carrier family 46 (folate transporter), member 1
chr11_+_45286911 1.83 ENSDART00000181763
pyrroline-5-carboxylate reductase 1b
chr23_-_36934944 1.76 ENSDART00000109976
ENSDART00000162179
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a
chr3_+_7771420 1.76 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr2_-_23391266 1.75 ENSDART00000159048
influenza virus NS1A binding protein b
chr23_-_31428763 1.74 ENSDART00000053545
zgc:153284
chr11_-_44194132 1.73 ENSDART00000182954
ENSDART00000111271

chr20_-_14114078 1.71 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr8_-_19467011 1.69 ENSDART00000162010
zgc:92140
chr15_-_20125331 1.69 ENSDART00000152355
mediator complex subunit 13b
chr5_+_9224051 1.66 ENSDART00000139265
si:ch211-12e13.12
chr12_-_26537145 1.63 ENSDART00000138437
ENSDART00000163931
ENSDART00000132737
acyl-CoA synthetase family member 2
chr22_+_33131891 1.63 ENSDART00000126885
dystroglycan 1
chr15_-_27522806 1.62 ENSDART00000149374
ENSDART00000187341
ENSDART00000183043
ENSDART00000189541
ENSDART00000190362
ENSDART00000193745
ENSDART00000187390
BRCA1 interacting protein C-terminal helicase 1
chr2_+_1989941 1.61 ENSDART00000190814
synovial sarcoma, X breakpoint 2 interacting protein a
chr4_-_75172216 1.59 ENSDART00000127522
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr1_-_54718863 1.59 ENSDART00000122601
phosphoglycerate mutase 1b
chr18_+_20034023 1.59 ENSDART00000139441
mortality factor 4 like 1
chr19_+_40069524 1.57 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr24_+_15020402 1.53 ENSDART00000148102
docking protein 6
chr11_+_12811906 1.48 ENSDART00000123445
regulator of telomere elongation helicase 1
chr14_+_989733 1.47 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr14_-_16082806 1.45 ENSDART00000165656
MAX dimerization protein 3
chr19_-_6840506 1.44 ENSDART00000081568
transcription factor 19 (SC1), like
chr22_+_33135253 1.43 ENSDART00000004504
dystroglycan 1
chr20_+_9223514 1.43 ENSDART00000023293
potassium channel, subfamily K, member 5b
chr25_+_7532811 1.41 ENSDART00000161593
phosphatidylserine synthase 2
chr16_+_21426524 1.41 ENSDART00000182869
gasdermin Eb
chr14_-_45967712 1.41 ENSDART00000043751
ENSDART00000141357
MACRO domain containing 1
chr7_+_36467315 1.40 ENSDART00000138893
akt interacting protein
chr5_+_22579975 1.40 ENSDART00000080877
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr3_-_25086986 1.40 ENSDART00000050245
X-prolyl aminopeptidase 3, mitochondrial
chr25_-_19574146 1.40 ENSDART00000156811
si:ch211-59o9.10
chr13_+_46944607 1.39 ENSDART00000187352
F-box protein 5
chr9_-_30247961 1.38 ENSDART00000131519
si:dkey-100n23.3
chr5_+_65086856 1.38 ENSDART00000169209
ENSDART00000162409
peptidyl-tRNA hydrolase 1 homolog
chr25_-_2723902 1.36 ENSDART00000143721
ENSDART00000175224
ADP-dependent glucokinase
chr21_-_37435162 1.36 ENSDART00000133585
family with sequence similarity 114, member A2
chr25_+_1335530 1.35 ENSDART00000090803
fem-1 homolog b (C. elegans)
chr6_+_4387150 1.35 ENSDART00000181283
RNA binding motif protein 26
chr19_+_14351560 1.34 ENSDART00000182732
AT rich interactive domain 1Ab (SWI-like)
chr9_+_42157578 1.34 ENSDART00000142888
leucine rich repeat containing 3
chr15_-_17099560 1.33 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr18_-_27316599 1.31 ENSDART00000028294
zgc:56106
chr14_+_7048930 1.30 ENSDART00000109138
heparin-binding EGF-like growth factor a
chr3_+_40576447 1.29 ENSDART00000083212
fascin actin-bundling protein 1a
chr7_-_64971839 1.27 ENSDART00000164682
SIN3-HDAC complex associated factor, like
chr25_-_29363934 1.26 ENSDART00000166889
neuroplastin a
chr12_+_27231212 1.26 ENSDART00000133023
ENSDART00000123739
transmembrane protein 106A
chr4_-_12477224 1.26 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
Rho guanine nucleotide exchange factor (GEF) 39
chr8_-_30395888 1.25 ENSDART00000144637
dedicator of cytokinesis 8
chr20_+_38543542 1.25 ENSDART00000145254
general transcription factor IIIC, polypeptide 2, beta
chr17_-_15188440 1.25 ENSDART00000151885
WD repeat and HMG-box DNA binding protein 1
chr7_+_10562118 1.24 ENSDART00000185188
ENSDART00000168801
zinc finger, AN1-type domain 6
chr8_-_16725959 1.22 ENSDART00000183593
DEP domain containing 1a
chr15_-_31265375 1.21 ENSDART00000086592
vascular endothelial zinc finger 1b
chr13_+_29925397 1.21 ENSDART00000123482
CUE domain containing 2
chr12_+_38563373 1.20 ENSDART00000134670
ENSDART00000193668
tweety family member 2
chr1_+_6646529 1.19 ENSDART00000144641
ENSDART00000103701
ENSDART00000138919
ubiquitin-conjugating enzyme E2F (putative)
chr5_+_65086668 1.19 ENSDART00000183746
peptidyl-tRNA hydrolase 1 homolog
chr4_+_15605844 1.18 ENSDART00000101619
ENSDART00000021384
exocyst complex component 4
chr10_+_32050906 1.18 ENSDART00000137373
si:ch211-266i6.3
chr20_+_9474841 1.18 ENSDART00000053847
RAD51 paralog B
chr10_-_32558917 1.18 ENSDART00000128888
ENSDART00000143301
monoacylglycerol O-acyltransferase 2
chr20_+_53368611 1.18 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr8_-_26709959 1.18 ENSDART00000135215
transmembrane protein 51a
chr20_+_23501535 1.18 ENSDART00000177922
ENSDART00000058532
palladin, cytoskeletal associated protein
chr17_+_28706946 1.17 ENSDART00000126967
striatin, calmodulin binding protein 3
chr1_-_45215343 1.17 ENSDART00000014727
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr19_-_27448606 1.17 ENSDART00000079251
valyl-tRNA synthetase 2, mitochondrial (putative)
chr18_+_49969568 1.16 ENSDART00000126916
MOB kinase activator 2b
chr2_-_27619954 1.15 ENSDART00000144826
trimethylguanosine synthase 1
chr2_+_29996650 1.15 ENSDART00000138050
ENSDART00000141026
RNA binding motif protein 33b
chr16_+_14010242 1.14 ENSDART00000059928
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr5_-_37117778 1.12 ENSDART00000149138
interleukin 13 receptor, alpha 2
chr23_+_4226341 1.12 ENSDART00000012445
zgc:113278
chr13_+_7241170 1.12 ENSDART00000109434
apoptosis-inducing factor, mitochondrion-associated, 2
chr21_-_42831033 1.12 ENSDART00000160998
serine/threonine kinase 10
chr23_+_31000243 1.11 ENSDART00000085263
selenoprotein I
chr15_-_25094026 1.11 ENSDART00000129154
exonuclease 5
chr21_-_36453417 1.10 ENSDART00000018350
CCR4-NOT transcription complex, subunit 8
chr18_+_6641542 1.08 ENSDART00000160379
C2 calcium-dependent domain containing 5
chr20_+_14114258 1.08 ENSDART00000044937
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr14_+_21238682 1.07 ENSDART00000054462
ENSDART00000138551
small integral membrane protein 19
chr11_-_27702778 1.07 ENSDART00000045942
ENSDART00000125352
PHD finger protein 2
chr9_+_1365747 1.05 ENSDART00000140917
ENSDART00000036605
protein kinase, interferon-inducible double stranded RNA dependent activator
chr1_+_46404968 1.05 ENSDART00000042064
tubulin, gamma complex associated protein 3
chr23_+_25292147 1.05 ENSDART00000131486
proliferation-associated 2G4, b
chr17_-_22573311 1.04 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exonuclease 1
chr11_-_18283886 1.04 ENSDART00000019248
STIM activating enhance
chr25_-_13789955 1.04 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
cytoskeleton associated protein 5
chr15_-_23529945 1.03 ENSDART00000152543
hydroxymethylbilane synthase, b
chr8_-_24970790 1.03 ENSDART00000141267
si:ch211-199o1.2
chr6_+_19948043 1.02 ENSDART00000182636
phosphoinositide-3-kinase, regulatory subunit 5
chr22_-_21845685 1.01 ENSDART00000105564
amino-terminal enhancer of split
chr16_-_7827365 1.01 ENSDART00000188101
T cell activation inhibitor, mitochondrial
chr13_-_24263682 1.01 ENSDART00000176800
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr13_+_22675802 1.01 ENSDART00000145538
ENSDART00000143312
zgc:193505
chr10_+_16225553 1.01 ENSDART00000129844
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr3_+_15893039 1.01 ENSDART00000055780
Jupiter microtubule associated homolog 2
chr3_-_47235997 0.99 ENSDART00000047071
transmembrane p24 trafficking protein 1a
chr3_+_27786601 0.99 ENSDART00000086994
N-acetyltransferase 15 (GCN5-related, putative)
chr18_-_39787040 0.98 ENSDART00000169916
Dmx-like 2
chr5_-_1869982 0.97 ENSDART00000055878
RNA terminal phosphate cyclase-like 1
chr8_-_7603700 0.97 ENSDART00000137975
interleukin-1 receptor-associated kinase 1
chr12_-_37449396 0.96 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr6_+_28018390 0.96 ENSDART00000123324
ENSDART00000150915
Sin3A-associated protein a
chr7_-_59210882 0.96 ENSDART00000170330
ENSDART00000158996
N-acetylglucosamine kinase
chr8_-_16674584 0.94 ENSDART00000100727
oxysterol binding protein-like 9
chr6_-_1780633 0.94 ENSDART00000160670
N-terminal asparagine amidase
chr3_-_52899394 0.94 ENSDART00000128223
coiled-coil-helix-coiled-coil-helix domain containing 5
chr16_+_7380463 0.93 ENSDART00000029727
ENSDART00000149086
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr4_-_75057322 0.93 ENSDART00000157935
LARGE xylosyl- and glucuronyltransferase 1
chr24_-_26981848 0.93 ENSDART00000183198
stromal antigen 1b
chr16_-_17345377 0.93 ENSDART00000143056
zyxin
chr22_+_737211 0.91 ENSDART00000017305
zinc finger protein 76
chr5_-_11809710 0.90 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
neurofibromin 2a (merlin)
chr23_+_1702624 0.89 ENSDART00000149357
Rab geranylgeranyltransferase, alpha subunit
chr5_-_30080332 0.89 ENSDART00000140049
beta-carotene oxygenase 2a
chr13_-_21650404 0.88 ENSDART00000078352
tetraspanin 14
chr3_+_41558682 0.88 ENSDART00000157023
caspase recruitment domain family, member 11
chr17_-_21200406 0.87 ENSDART00000104708
abhydrolase domain containing 12
chr16_+_25296389 0.86 ENSDART00000114528
TBC1 domain family, member 31
chr23_-_19051869 0.86 ENSDART00000140866
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr8_-_26792912 0.86 ENSDART00000139787
kazrin, periplakin interacting protein a
chr8_+_28452738 0.86 ENSDART00000062706
transmembrane protein 189
chr21_-_2814709 0.86 ENSDART00000097664
semaphorin 4D
chr2_+_34967022 0.85 ENSDART00000134926
astrotactin 1
chr24_+_37709191 0.85 ENSDART00000066558
2,4-dienoyl CoA reductase 2, peroxisomal
chr12_+_19138452 0.85 ENSDART00000141346
ENSDART00000066397
PHD finger protein 5A
chr23_+_7710447 0.84 ENSDART00000168199
kinesin family member 3B
chr12_+_3262564 0.84 ENSDART00000184264
transmembrane protein 101
chr7_+_7696665 0.84 ENSDART00000091099
INO80 complex subunit B
chr25_+_20272145 0.83 ENSDART00000109605
si:dkey-219c3.2
chr7_-_12789251 0.83 ENSDART00000052750
ADAMTS-like 3
chr7_+_9326234 0.82 ENSDART00000104536
chondroitin sulfate synthase 1
chr10_-_9961488 0.82 ENSDART00000191023
spermatid perinuclear RNA binding protein
chr14_+_22467672 0.82 ENSDART00000079409
ENSDART00000136597
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr2_+_19195841 0.81 ENSDART00000163137
ENSDART00000161095
ELOVL fatty acid elongase 1a
chr20_+_28803642 0.80 ENSDART00000188526
farnesyltransferase, CAAX box, beta
chr13_+_11436130 0.80 ENSDART00000169895
zinc finger and BTB domain containing 18
chr15_-_16384184 0.80 ENSDART00000154504
family with sequence similarity 222, member Bb
chr3_-_39190317 0.80 ENSDART00000013167
retinol saturase (all-trans-retinol 13,14-reductase)
chr2_+_1881334 0.79 ENSDART00000161420
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr23_-_36439961 0.79 ENSDART00000187907
cysteine sulfinic acid decarboxylase
chr5_+_42124706 0.79 ENSDART00000020044
ENSDART00000156372
sedoheptulokinase
chr6_+_45494227 0.78 ENSDART00000159863
contactin 4
chr6_-_50685862 0.78 ENSDART00000134146
metastasis suppressor 1
chr24_+_26140855 0.77 ENSDART00000139017
teleost multiple tissue opsin b
chr11_+_1867613 0.77 ENSDART00000065470
RNA binding motif, single stranded interacting protein 2a
chr12_+_22580579 0.75 ENSDART00000171725
ENSDART00000192290
capping protein (actin filament), gelsolin-like b
chr3_+_17806213 0.74 ENSDART00000055890
zinc finger protein 385C
chr7_-_16195144 0.74 ENSDART00000173492
bloodthirsty-related gene family, member 4
chr20_+_54333774 0.74 ENSDART00000144633
CLOCK-interacting pacemaker b
chr22_+_12595144 0.73 ENSDART00000140054
ENSDART00000060979
ENSDART00000139826
zgc:92335
chr8_-_14554785 0.73 ENSDART00000057645
quiescin Q6 sulfhydryl oxidase 1
chr6_-_9646275 0.73 ENSDART00000012903
WD repeat domain 12
chr14_-_30905288 0.72 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
chr13_+_45476181 0.72 ENSDART00000045329
microsomal glutathione S-transferase 3b
chr14_-_33981544 0.72 ENSDART00000167774
forkhead box A sequence
chr11_+_30282141 0.71 ENSDART00000122756
si:dkey-163f14.6
chr5_+_1493767 0.71 ENSDART00000022132
HAUS augmin-like complex, subunit 4
chr8_+_37749263 0.71 ENSDART00000108556
ENSDART00000147942
nucleophosmin/nucleoplasmin, 2a
chr3_-_39305291 0.71 ENSDART00000102674
phospholipase C, delta 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of foxl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.4 1.3 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.4 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 3.5 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.4 3.1 GO:0033292 T-tubule organization(GO:0033292)
0.4 1.1 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.4 2.1 GO:0010269 response to selenium ion(GO:0010269)
0.3 2.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.3 1.4 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 2.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 1.0 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.3 1.6 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.3 0.9 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.3 1.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 2.9 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.3 1.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 1.3 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.3 2.0 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.3 0.5 GO:0051645 Golgi localization(GO:0051645)
0.2 2.7 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 1.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.2 0.6 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.2 2.2 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 1.8 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.2 1.1 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 0.6 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.2 1.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2 0.7 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.2 0.9 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 0.9 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2 0.5 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2 1.0 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.2 0.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 1.5 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.2 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 1.0 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 6.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 1.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.7 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.4 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 0.8 GO:0060876 semicircular canal formation(GO:0060876)
0.1 1.5 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 1.7 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.5 GO:0010758 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.1 0.7 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.9 GO:0043584 nose development(GO:0043584)
0.1 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.9 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.4 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 1.0 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.9 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 1.0 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.5 GO:0071543 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.9 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 0.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.5 GO:1904396 regulation of neuromuscular junction development(GO:1904396)
0.1 0.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 4.8 GO:0030901 midbrain development(GO:0030901)
0.1 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.6 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.1 0.5 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.7 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 2.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 2.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.4 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.1 0.6 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 1.0 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 2.5 GO:0043588 skin development(GO:0043588)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.6 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 2.4 GO:0006284 base-excision repair(GO:0006284)
0.1 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.5 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.2 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.5 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 3.0 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 1.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.0 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.0 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.5 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.9 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 2.6 GO:0006096 glycolytic process(GO:0006096)
0.0 1.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.4 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 2.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 2.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.9 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 1.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.6 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.8 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.1 GO:0007620 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.7 GO:0051014 actin filament severing(GO:0051014)
0.0 0.8 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.4 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 1.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.5 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.6 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807) SNARE complex disassembly(GO:0035494)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.9 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.9 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 2.5 GO:0032259 methylation(GO:0032259)
0.0 2.4 GO:0006631 fatty acid metabolic process(GO:0006631)
0.0 0.9 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 1.2 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.1 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.6 GO:0032147 activation of protein kinase activity(GO:0032147)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.3 3.1 GO:0016011 dystroglycan complex(GO:0016011)
0.3 1.2 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.0 GO:0043291 RAVE complex(GO:0043291)
0.2 0.7 GO:0070545 PeBoW complex(GO:0070545)
0.2 1.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 1.4 GO:0070695 FHF complex(GO:0070695)
0.2 0.9 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 1.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 0.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 2.5 GO:0014704 intercalated disc(GO:0014704)
0.2 2.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.3 GO:0035060 brahma complex(GO:0035060)
0.1 3.0 GO:0070822 Sin3-type complex(GO:0070822)
0.1 2.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.4 GO:0034657 GID complex(GO:0034657)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.5 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 1.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.0 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.5 GO:0032797 SMN complex(GO:0032797)
0.1 1.5 GO:0005686 U2 snRNP(GO:0005686)
0.1 5.0 GO:0030141 secretory granule(GO:0030141)
0.1 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 2.7 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 3.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.7 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.9 GO:0008278 cohesin complex(GO:0008278)
0.0 1.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 4.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 2.6 GO:0030027 lamellipodium(GO:0030027)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0042641 stress fiber(GO:0001725) actomyosin(GO:0042641) contractile actin filament bundle(GO:0097517)
0.0 1.1 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 4.5 GO:0005764 lysosome(GO:0005764)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 5.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.0 1.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.9 GO:0005938 cell cortex(GO:0005938)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.5 1.6 GO:0031956 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.5 2.3 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.4 1.6 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.4 1.9 GO:0009374 biotin binding(GO:0009374)
0.4 1.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4 1.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.4 1.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 1.8 GO:0005542 folic acid binding(GO:0005542)
0.4 2.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 1.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 2.0 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.4 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.3 3.6 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.3 2.3 GO:0008494 translation activator activity(GO:0008494)
0.2 0.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.9 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 1.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 0.7 GO:0034246 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.2 0.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 2.1 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 0.5 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 1.0 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.2 0.7 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.2 1.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 0.6 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.2 3.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 3.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.8 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 3.0 GO:0043236 laminin binding(GO:0043236)
0.1 0.5 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.9 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 1.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 2.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.4 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.1 0.9 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.8 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.9 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.9 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 1.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.5 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 5.6 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.1 0.6 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 1.2 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 2.6 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 1.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.8 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 3.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 2.0 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.9 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 2.3 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 1.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 3.4 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.6 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.0 0.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 1.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 7.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 1.4 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.5 GO:0019955 cytokine binding(GO:0019955)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0070330 aromatase activity(GO:0070330)
0.0 2.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 1.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 3.8 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 3.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 2.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 1.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis