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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxh1+foxq1a+foxq1b

Z-value: 1.02

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Transcription factors associated with foxh1+foxq1a+foxq1b

Gene Symbol Gene ID Gene Info
ENSDARG00000030896 forkhead box Q1a
ENSDARG00000055395 forkhead box Q1b
ENSDARG00000055630 forkhead box H1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxq1adr11_v1_chr2_-_722156_7221700.701.3e-03Click!
foxh1dr11_v1_chr12_-_13729263_137292630.561.6e-02Click!
foxq1bdr11_v1_chr20_+_26683933_26683940-0.322.0e-01Click!

Activity profile of foxh1+foxq1a+foxq1b motif

Sorted Z-values of foxh1+foxq1a+foxq1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_15960514 2.38 ENSDART00000181617
scl/tal1 interrupting locus
chr10_-_6587066 2.25 ENSDART00000171833
chromodomain helicase DNA binding protein 1
chr17_+_25856671 2.23 ENSDART00000064817
WAPL cohesin release factor a
chr17_+_15534815 2.21 ENSDART00000159426
myristoylated alanine-rich protein kinase C substrate b
chr7_+_28724919 2.20 ENSDART00000011324
coiled-coil domain containing 102A
chr22_+_15960005 2.12 ENSDART00000033617
scl/tal1 interrupting locus
chr22_+_15959844 2.11 ENSDART00000182201
scl/tal1 interrupting locus
chr19_+_25971000 2.06 ENSDART00000089836
jumonji, AT rich interactive domain 2b
chr21_-_44772738 1.96 ENSDART00000026178
kinesin family member 4
chr7_-_53117131 1.95 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr7_-_19999152 1.84 ENSDART00000173881
ENSDART00000100798
thyroid hormone receptor interactor 6
chr12_+_5251647 1.80 ENSDART00000124097
phospholipase C, epsilon 1
chr14_+_28486213 1.80 ENSDART00000161852
stromal antigen 2b
chr1_+_26676758 1.76 ENSDART00000152299
si:dkey-25o16.4
chr7_-_60351537 1.70 ENSDART00000159875
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr7_-_60351876 1.69 ENSDART00000098563
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr17_+_28005763 1.65 ENSDART00000155838
leucine zipper protein 1
chr1_+_19538299 1.63 ENSDART00000109416
structural maintenance of chromosomes 2
chr17_+_26803470 1.60 ENSDART00000023470
progesterone receptor membrane component 2
chr23_-_43595956 1.52 ENSDART00000162186
itchy E3 ubiquitin protein ligase b
chr13_+_25286538 1.50 ENSDART00000180282
conserved helix-loop-helix ubiquitous kinase
chr1_+_53321878 1.50 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr8_-_11324143 1.46 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr7_-_19998723 1.44 ENSDART00000173458
thyroid hormone receptor interactor 6
chr11_-_25257045 1.43 ENSDART00000130477
snail family zinc finger 1a
chr5_-_45958838 1.42 ENSDART00000135072
POC5 centriolar protein homolog (Chlamydomonas)
chr7_+_24153070 1.41 ENSDART00000076735
low density lipoprotein receptor-related protein 10
chr11_-_25257595 1.35 ENSDART00000123567
snail family zinc finger 1a
chr17_+_24590177 1.34 ENSDART00000092941
rearranged L-myc fusion
chr9_+_34397843 1.33 ENSDART00000146314
mediator complex subunit 14
chr21_+_4116437 1.32 ENSDART00000167791
ENSDART00000123759
Rap guanine nucleotide exchange factor (GEF) 1b
chr17_-_23709347 1.31 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr17_-_15546862 1.30 ENSDART00000091021
collagen, type X, alpha 1a
chr22_+_24559947 1.25 ENSDART00000169847
WD repeat domain 47b
chr8_+_11425048 1.23 ENSDART00000018739
tight junction protein 2b (zona occludens 2)
chr16_-_39267185 1.21 ENSDART00000058550
ENSDART00000133642
glycerol-3-phosphate dehydrogenase 1 like
chr1_-_23370395 1.19 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
PDS5 cohesin associated factor A
chr13_-_25198025 1.19 ENSDART00000159585
ENSDART00000144227
adenosine kinase a
chr9_+_34397516 1.18 ENSDART00000011304
ENSDART00000192973
mediator complex subunit 14
chr23_+_38159715 1.13 ENSDART00000137969
zgc:112994
chr3_-_37148594 1.12 ENSDART00000140855
MLX, MAX dimerization protein
chr8_-_25034411 1.10 ENSDART00000135973
nuclear transcription factor Y, alpha, like
chr8_+_8643901 1.08 ENSDART00000142076
ENSDART00000075624
ubiquitin specific peptidase 11
chr15_-_37875601 1.07 ENSDART00000122439
si:dkey-238d18.4
chr5_+_25762271 1.07 ENSDART00000181323
transmembrane protein 2
chr22_+_14117078 1.06 ENSDART00000013575
basic leucine zipper and W2 domains 1a
chr14_+_34495216 1.06 ENSDART00000147756
wingless-type MMTV integration site family, member 8a
chr5_+_8196264 1.03 ENSDART00000174564
ENSDART00000161261
LMBR1 domain containing 2a
chr7_+_9290929 1.03 ENSDART00000128530
small nuclear ribonucleoprotein polypeptide A'
chr16_-_42461263 1.02 ENSDART00000109259
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
chr17_+_15559046 1.01 ENSDART00000187126
BTB and CNC homology 1, basic leucine zipper transcription factor 2a
chr22_-_5171829 1.00 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr18_+_20034023 0.99 ENSDART00000139441
mortality factor 4 like 1
chr6_+_54680730 0.98 ENSDART00000074602
sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase)
chr17_-_11417551 0.98 ENSDART00000128291
AT rich interactive domain 4A (RBP1-like)
chr6_-_19341184 0.98 ENSDART00000168236
ENSDART00000167674
MIF4G domain containing a
chr12_+_19408373 0.97 ENSDART00000114248
sorting nexin 29
chr3_+_34234029 0.97 ENSDART00000044859
zinc finger protein 207, a
chr24_+_37338169 0.97 ENSDART00000141771
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr9_-_30494727 0.97 ENSDART00000148729
si:dkey-229b18.3
chr4_+_75200467 0.95 ENSDART00000122593

chr16_+_46410520 0.94 ENSDART00000131072
rapunzel 2
chr17_-_11417904 0.93 ENSDART00000103228
AT rich interactive domain 4A (RBP1-like)
chr11_-_27057572 0.93 ENSDART00000043091
IQ motif and Sec7 domain 1b
chr20_-_44055095 0.93 ENSDART00000125898
ENSDART00000082265
runt-related transcription factor 2b
chr22_-_29906764 0.92 ENSDART00000019786
structural maintenance of chromosomes 3
chr2_+_7132292 0.92 ENSDART00000153404
ENSDART00000012119
zgc:110366
chr8_-_44223899 0.90 ENSDART00000143020
syntaxin 2b
chr14_-_31694274 0.90 ENSDART00000173353
MAP7 domain containing 3
chr15_+_29662401 0.90 ENSDART00000135540
nuclear receptor interacting protein 1a
chr4_+_2637947 0.89 ENSDART00000130623
dihydrouridine synthase 4-like (S. cerevisiae)
chr4_+_25181572 0.88 ENSDART00000078529
ENSDART00000136643
Kin17 DNA and RNA binding protein
chr3_-_49138004 0.87 ENSDART00000167173
GIPC PDZ domain containing family, member 1
chr9_-_27398369 0.86 ENSDART00000186499
testis expressed 30
chr8_-_44223473 0.85 ENSDART00000098525
syntaxin 2b
chr16_+_35536075 0.85 ENSDART00000183618
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr7_+_38808027 0.84 ENSDART00000052323
harbinger transposase derived 1
chr25_+_388258 0.84 ENSDART00000166834
regulatory factor X7b
chr15_-_17169935 0.83 ENSDART00000110111
cullin 5a
chr13_-_23956178 0.83 ENSDART00000133646
phosphatase and actin regulator 2
chr15_+_21712328 0.83 ENSDART00000192553
zgc:162339
chr6_-_8466717 0.83 ENSDART00000151577
ENSDART00000151800
ENSDART00000151227
si:dkey-217d24.6
chr3_+_50172452 0.82 ENSDART00000191224
epsin 3a
chr5_-_13766651 0.81 ENSDART00000134064
MAX dimerization protein 1
chr19_+_43004408 0.80 ENSDART00000038230
small nuclear ribonucleoprotein 40 (U5)
chrM_+_6425 0.79 ENSDART00000093606
cytochrome c oxidase I, mitochondrial
chr13_-_23956361 0.79 ENSDART00000101150
phosphatase and actin regulator 2
chr12_-_23365737 0.78 ENSDART00000170376
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr25_+_2776865 0.77 ENSDART00000156567
neogenin 1b
chr3_-_50139860 0.77 ENSDART00000101563
bloodthirsty-related gene family, member 2
chr2_+_15128418 0.76 ENSDART00000141921
Rho GTPase activating protein 29b
chr5_-_32074534 0.74 ENSDART00000112342
ENSDART00000135855
actin related protein 2/3 complex, subunit 5-like, b
chr13_+_39182099 0.74 ENSDART00000131434
family with sequence similarity 135, member A
chr24_-_37338162 0.72 ENSDART00000056303
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr23_+_22819971 0.71 ENSDART00000111345
arginine-glutamic acid dipeptide (RE) repeats a
chr5_-_67365750 0.70 ENSDART00000062359
uracil DNA glycosylase a
chr21_-_38153824 0.70 ENSDART00000151226
Kruppel-like factor 5 like
chr7_-_26076970 0.70 ENSDART00000101120
zgc:92664
chr18_+_13077800 0.69 ENSDART00000161153
gigaxonin
chr7_+_22801465 0.67 ENSDART00000052862
ENSDART00000173633
RNA binding motif protein 4.1
chr23_+_39970425 0.66 ENSDART00000165376
FYVE and coiled-coil domain containing 1a
chr3_+_59864872 0.65 ENSDART00000102014
MAPK regulated corepressor interacting protein 1
chr11_+_24348425 0.64 ENSDART00000089747
NFS1 cysteine desulfurase
chr12_-_5455936 0.63 ENSDART00000109305
TBC1 domain family, member 12b
chr8_+_40476811 0.63 ENSDART00000129772
glucokinase (hexokinase 4)
chr3_+_40284598 0.61 ENSDART00000009411
BUD31 homolog (S. cerevisiae)
chr3_-_42086577 0.61 ENSDART00000083111
ENSDART00000187312
tweety family member 3a
chr23_-_41762956 0.61 ENSDART00000128302
serine/threonine kinase 35
chr19_-_46018152 0.61 ENSDART00000159206
KRIT1, ankyrin repeat containing
chr5_-_43682930 0.61 ENSDART00000075017
si:dkey-40c11.1
chr3_+_54047342 0.59 ENSDART00000178486
olfactomedin 2a
chr8_-_15150131 0.57 ENSDART00000138253
BCAR3, NSP family adaptor protein
chr16_+_35535375 0.55 ENSDART00000171675
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr12_-_31422433 0.55 ENSDART00000186075
ENSDART00000153172
ENSDART00000066256
vesicle transport through interaction with t-SNAREs 1A
chr9_+_7030016 0.54 ENSDART00000148047
ENSDART00000148181
inositol polyphosphate-4-phosphatase type I Aa
chr18_-_45761868 0.53 ENSDART00000025423
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr23_+_2191773 0.53 ENSDART00000190876
ENSDART00000126768
coiled-coil and C2 domain containing 2A
chr4_+_15011341 0.53 ENSDART00000124452
ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
chr16_+_25116827 0.52 ENSDART00000163244
si:ch211-261d7.6
chr12_+_27704015 0.51 ENSDART00000153256
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr7_+_46003449 0.51 ENSDART00000159700
ENSDART00000173625
si:ch211-260e23.9
chr14_-_15990361 0.51 ENSDART00000168075
tripartite motif containing 105
chr23_+_38957472 0.50 ENSDART00000193836
ATPase phospholipid transporting 9A (putative)
chr4_-_12102025 0.48 ENSDART00000048391
ENSDART00000023894
B-Raf proto-oncogene, serine/threonine kinase
chr24_+_32472155 0.48 ENSDART00000098859
neuronal differentiation 6a
chr17_+_24111392 0.48 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
EH domain binding protein 1
chr5_-_37997774 0.45 ENSDART00000139616
ENSDART00000167694
si:dkey-111e8.1
chr12_-_20120702 0.44 ENSDART00000153387
ENSDART00000158412
ENSDART00000112768
UBA-like domain containing 1a
chr3_+_40289418 0.44 ENSDART00000017304
cleavage and polyadenylation specific factor 4
chr1_+_32054159 0.43 ENSDART00000181442
steroid sulfatase (microsomal), isozyme S
chr4_+_23125689 0.43 ENSDART00000077854
MDM2 oncogene, E3 ubiquitin protein ligase
chr23_-_41762797 0.42 ENSDART00000186564
serine/threonine kinase 35
chr10_+_573667 0.41 ENSDART00000110384
SMAD family member 4a
chr10_+_43117661 0.40 ENSDART00000024644
ENSDART00000186932
X-ray repair complementing defective repair in Chinese hamster cells 4
chr12_-_28537615 0.40 ENSDART00000067762
si:ch211-94l19.4
chr11_-_8126223 0.40 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr2_+_8649293 0.40 ENSDART00000081442
ENSDART00000186024
far upstream element (FUSE) binding protein 1
chr16_+_29586468 0.39 ENSDART00000148926
MCL1, BCL2 family apoptosis regulator b
chr15_-_7337148 0.39 ENSDART00000182568
high affinity cationic amino acid transporter 1
chr11_-_24523161 0.38 ENSDART00000191936
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr19_+_33476557 0.38 ENSDART00000181800
triple QxxK/R motif containing
chr15_-_7337537 0.38 ENSDART00000161613
high affinity cationic amino acid transporter 1
chr10_+_15107886 0.37 ENSDART00000188047
ENSDART00000164095
secretory calcium-binding phosphoprotein 8
chr20_-_29505863 0.37 ENSDART00000148278
Kruppel-like factor 11a
chr9_+_34950942 0.37 ENSDART00000077800
transcription factor Dp-1, a
chr25_-_26893006 0.37 ENSDART00000006709
dihydrolipoamide dehydrogenase
chr2_+_31957554 0.36 ENSDART00000012413
ANKH inorganic pyrophosphate transport regulator b
chr21_+_17542473 0.35 ENSDART00000005750
ENSDART00000141326
stomatin
chr7_+_30240791 0.33 ENSDART00000109243
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr5_-_33769211 0.32 ENSDART00000133504
DAB2 interacting protein b
chr5_-_28767573 0.32 ENSDART00000158299
ENSDART00000043466
Tnf receptor-associated factor 2a
chr1_+_14658801 0.30 ENSDART00000192194

chr17_-_12764360 0.30 ENSDART00000003418
breast cancer metastasis-suppressor 1-like a
chr1_-_45580787 0.29 ENSDART00000135089
activating transcription factor 7 interacting protein
chr18_+_15644559 0.29 ENSDART00000061794
nuclear receptor subfamily 1, group H, member 4
chr19_-_17526735 0.28 ENSDART00000189391
thyroid hormone receptor beta
chr18_+_30421528 0.27 ENSDART00000140908
Gse1 coiled-coil protein
chr15_-_36727462 0.27 ENSDART00000085971
nephrosis 1, congenital, Finnish type (nephrin)
chr11_+_24046179 0.26 ENSDART00000006703
MAF1 homolog, negative regulator of RNA polymerase III
chr13_+_18507592 0.25 ENSDART00000142622
si:ch211-198a12.6
chr17_-_44440832 0.25 ENSDART00000148786
exocyst complex component 5
chr3_-_40284744 0.25 ENSDART00000018626
pdgfa associated protein 1b
chr1_-_53756851 0.23 ENSDART00000122445
v-akt murine thymoma viral oncogene homolog 3b
chr25_+_18711804 0.22 ENSDART00000011149
family with sequence similarity 185, member A
chr14_-_7207961 0.22 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr7_-_15118140 0.21 ENSDART00000179985
si:dkey-172h23.2
chr17_+_44441042 0.21 ENSDART00000142123
adaptor-related protein complex 5, mu 1 subunit
chr21_+_26733529 0.20 ENSDART00000168379
pyruvate carboxylase a
chr9_+_20554896 0.20 ENSDART00000144248
mannosidase, alpha, class 1A, member 2
chr15_+_7992906 0.20 ENSDART00000090790
cell adhesion molecule 2b
chr22_-_7461603 0.19 ENSDART00000170630

chr25_-_3647277 0.18 ENSDART00000166363
si:ch211-272n13.3
chr10_-_27009413 0.18 ENSDART00000139942
ENSDART00000146983
ENSDART00000132352
ubiquinol-cytochrome c reductase complex assembly factor 3
chr12_+_32729470 0.18 ENSDART00000175712
RNA binding fox-1 homolog 3a
chr16_-_17056630 0.18 ENSDART00000138715
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr6_-_9792004 0.17 ENSDART00000081129
cyclin-dependent kinase 15
chr7_+_30254652 0.17 ENSDART00000173711
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr4_+_11723852 0.16 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr16_-_21692024 0.15 ENSDART00000123597
si:ch211-154o6.2
chr7_-_17425535 0.15 ENSDART00000098053
ENSDART00000161873
novel immune-type receptor 3c
chr24_-_26854032 0.15 ENSDART00000087991
fibronectin type III domain containing 3Bb
chr20_-_16156419 0.14 ENSDART00000037420
Ral GEF with PH domain and SH3 binding motif 2
chr16_-_30563129 0.14 ENSDART00000191716
lamin A
chr22_-_15437242 0.14 ENSDART00000063719
ribonuclease P 21 subunit
chr3_+_29714775 0.12 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr8_+_4803906 0.12 ENSDART00000045533
transmembrane protein 127
chr1_+_44711446 0.11 ENSDART00000193481
ENSDART00000003895
structure specific recognition protein 1b
chr16_-_9675982 0.10 ENSDART00000113724
mal, T cell differentiation protein 2 (gene/pseudogene)
chr10_+_9595575 0.10 ENSDART00000091780
ENSDART00000184287
ring finger and CCCH-type domains 2
chr19_+_4139065 0.09 ENSDART00000172524
si:dkey-218f9.10
chr2_+_36701322 0.07 ENSDART00000002510
golgi integral membrane protein 4b
chr14_-_32403554 0.07 ENSDART00000172873
ENSDART00000173408
ENSDART00000173114
ENSDART00000185594
ENSDART00000186762
ENSDART00000010982
fibroblast growth factor 13a
chr5_-_15321451 0.06 ENSDART00000139203
thioredoxin reductase 2, tandem duplicate 1
chr10_+_43039947 0.06 ENSDART00000193434
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr4_-_1908179 0.06 ENSDART00000139586
anoctamin 6
chr9_+_17306162 0.05 ENSDART00000075926
sciellin
chr21_+_21673516 0.05 ENSDART00000147601
odorant receptor, family E, subfamily 125, member 6
chr6_-_6423885 0.05 ENSDART00000092257
si:ch211-194e18.2
chr10_-_25816558 0.04 ENSDART00000017240
periostin, osteoblast specific factor a
chr15_-_19334448 0.04 ENSDART00000062576
thymocyte nuclear protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxh1+foxq1a+foxq1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.7 6.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.7 2.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 1.3 GO:0050428 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.4 3.3 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.4 1.1 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.4 1.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.9 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.3 1.2 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.3 1.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 2.8 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.2 1.6 GO:0030728 ovulation(GO:0030728)
0.2 0.6 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.2 3.4 GO:0090279 regulation of calcium ion import(GO:0090279)
0.2 1.2 GO:0044209 AMP salvage(GO:0044209)
0.2 0.8 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.2 2.8 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.7 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.1 0.7 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.7 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 1.0 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.7 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.6 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 0.4 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 2.5 GO:0019827 stem cell population maintenance(GO:0019827)
0.1 2.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.4 GO:0051103 DNA ligation(GO:0006266) immunoglobulin V(D)J recombination(GO:0033152) DNA ligation involved in DNA repair(GO:0051103)
0.1 0.3 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 1.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.5 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 1.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.7 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 1.0 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 1.6 GO:0030261 chromosome condensation(GO:0030261)
0.0 1.5 GO:0070936 posterior lateral line neuromast primordium migration(GO:0048920) protein K48-linked ubiquitination(GO:0070936)
0.0 1.4 GO:0007632 visual behavior(GO:0007632)
0.0 0.6 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 1.0 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 2.0 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 3.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.3 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.3 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.1 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.3 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.0 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.7 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.3 GO:0031101 fin regeneration(GO:0031101)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0055026 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0070847 core mediator complex(GO:0070847)
0.4 1.1 GO:0097189 apoptotic body(GO:0097189)
0.3 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 1.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.7 GO:0016589 NURF complex(GO:0016589)
0.1 2.7 GO:0008278 cohesin complex(GO:0008278)
0.1 1.9 GO:0030057 desmosome(GO:0030057)
0.1 1.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 5.5 GO:0032432 actin filament bundle(GO:0032432)
0.1 1.0 GO:0016580 Sin3 complex(GO:0016580)
0.1 6.2 GO:0005814 centriole(GO:0005814)
0.1 1.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.0 GO:0071564 npBAF complex(GO:0071564)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.8 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 1.3 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 1.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.3 1.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.2 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 0.7 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 2.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 1.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.9 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 5.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 0.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 1.0 GO:0008494 translation activator activity(GO:0008494)
0.1 0.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0043621 protein self-association(GO:0043621)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.7 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 2.3 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.1 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 3.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.8 PID ATM PATHWAY ATM pathway
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4 3.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 1.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism