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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxd3

Z-value: 2.45

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Transcription factors associated with foxd3

Gene Symbol Gene ID Gene Info
ENSDARG00000021032 forkhead box D3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxd3dr11_v1_chr6_-_32093830_32093830-0.682.0e-03Click!

Activity profile of foxd3 motif

Sorted Z-values of foxd3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_28888975 10.09 ENSDART00000076362
phosphorylase kinase, gamma 2 (testis)
chr22_+_24559947 8.20 ENSDART00000169847
WD repeat domain 47b
chr6_-_25201810 6.52 ENSDART00000168683
leucine rich repeat containing 8 VRAC subunit C
chr17_+_14965570 6.51 ENSDART00000066604
G protein-coupled receptor 137c
chr15_+_38299385 6.36 ENSDART00000142403
si:dkey-24p1.6
chr15_+_38299563 5.94 ENSDART00000099375
si:dkey-24p1.6
chr1_-_33647138 5.60 ENSDART00000142111
ENSDART00000015547
claudin g
chr14_-_16082806 5.27 ENSDART00000165656
MAX dimerization protein 3
chr17_-_4245902 5.23 ENSDART00000151851
growth differentiation factor 3
chr14_+_32926385 4.96 ENSDART00000139159
ligand of numb-protein X 2b
chr15_-_16076399 4.90 ENSDART00000135658
ENSDART00000133755
ENSDART00000080413
serine/arginine-rich splicing factor 1a
chr5_+_57924611 4.82 ENSDART00000050949
B-cell translocation gene 4
chr3_+_53116172 4.72 ENSDART00000115117
bromodomain containing 4
chr2_-_44777592 4.58 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr12_-_11349899 4.42 ENSDART00000079645
zgc:174164
chr6_+_4255319 4.39 ENSDART00000170351
neurobeachin-like 1
chr22_-_28777557 4.33 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
chr15_+_19990068 4.33 ENSDART00000154033
ENSDART00000054428
zgc:112083
chr19_+_25971000 4.22 ENSDART00000089836
jumonji, AT rich interactive domain 2b
chr22_-_28777374 4.08 ENSDART00000188206
si:dkeyp-34c12.1
chr20_-_4793450 4.02 ENSDART00000053870
galactosylceramidase a
chr11_+_45286911 4.02 ENSDART00000181763
pyrroline-5-carboxylate reductase 1b
chr13_+_11828516 3.99 ENSDART00000110141
suppressor of fused homolog (Drosophila)
chr22_-_22337382 3.95 ENSDART00000144684
si:ch211-129c21.1
chr15_-_44052927 3.93 ENSDART00000166209
wu:fb44b02
chr18_+_15271993 3.90 ENSDART00000099777
si:dkey-103i16.6
chr1_-_6028876 3.87 ENSDART00000168117
si:ch1073-345a8.1
chr3_-_34561624 3.83 ENSDART00000129313
septin 9a
chr3_-_43650189 3.82 ENSDART00000161127
axin 1
chr14_-_34633960 3.82 ENSDART00000128869
ENSDART00000179977
actin filament associated protein 1-like 1a
chr12_-_17863467 3.81 ENSDART00000042006
BAI1-associated protein 2-like 1a
chr16_+_23487051 3.69 ENSDART00000145496
ictacalcin 2
chr1_-_33645967 3.67 ENSDART00000192758
claudin g
chr5_+_31214341 3.67 ENSDART00000133432
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr20_+_29209767 3.66 ENSDART00000141252
katanin p80 subunit B-like 1
chr11_+_18612421 3.59 ENSDART00000110621
nuclear receptor coactivator 3
chr17_+_32622933 3.57 ENSDART00000077418
cathepsin Ba
chr5_-_13766651 3.56 ENSDART00000134064
MAX dimerization protein 1
chr5_+_3891485 3.52 ENSDART00000129329
ENSDART00000091711
RPA interacting protein
chr3_-_34528306 3.51 ENSDART00000023039
septin 9a
chr22_-_17671348 3.47 ENSDART00000137995
tight junction protein 3
chr21_-_13856689 3.46 ENSDART00000102197
family with sequence similarity 129, member Ba
chr20_+_29209926 3.43 ENSDART00000152949
ENSDART00000153016
katanin p80 subunit B-like 1
chr10_-_14929392 3.42 ENSDART00000137430
SMAD family member 2
chr7_+_24023653 3.40 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr8_+_10862353 3.40 ENSDART00000140717
bromodomain and PHD finger containing, 3b
chr23_+_36730713 3.39 ENSDART00000113179
tetraspanin 31
chr19_+_1510971 3.38 ENSDART00000157721
solute carrier family 45 member 4
chr3_-_26191960 3.38 ENSDART00000113843
yippee-like 3
chr6_-_41135215 3.37 ENSDART00000001861
solute carrier family 6 member 22, tandem duplicate 1
chr13_-_22961605 3.36 ENSDART00000143112
ENSDART00000057641
tetraspanin 15
chr20_+_29209615 3.34 ENSDART00000062350
katanin p80 subunit B-like 1
chr17_-_40956035 3.29 ENSDART00000124715
si:dkey-16j16.4
chr7_-_51773166 3.23 ENSDART00000054591
bone morphogenetic protein 15
chr23_+_22873415 3.22 ENSDART00000135130
arginine-glutamic acid dipeptide (RE) repeats a
chr16_+_43077909 3.18 ENSDART00000014140
RUN domain containing 3b
chr6_+_2174082 3.18 ENSDART00000073936
activin A receptor type 1Bb
chr12_+_20691310 3.17 ENSDART00000064335
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr17_+_25856671 3.17 ENSDART00000064817
WAPL cohesin release factor a
chr9_+_27720428 3.16 ENSDART00000112415
leucine carboxyl methyltransferase 2
chr13_+_25397098 3.15 ENSDART00000132953
glutathione S-transferase omega 2
chr12_-_35505610 3.13 ENSDART00000105518
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr13_+_25396896 3.12 ENSDART00000041257
glutathione S-transferase omega 2
chr12_-_25380028 3.11 ENSDART00000142674
zinc finger protein 36, C3H type-like 2
chr2_+_31437547 3.11 ENSDART00000141170
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr6_-_40922971 3.11 ENSDART00000155363
SFI1 centrin binding protein
chr1_+_45707219 3.10 ENSDART00000143363
si:ch211-214c7.4
chr2_+_15069011 3.09 ENSDART00000145893
calponin 3, acidic b
chr12_+_11650146 3.08 ENSDART00000150191
WAPL cohesin release factor b
chr7_+_52712807 3.07 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr5_+_13472234 3.06 ENSDART00000114069
ENSDART00000132406
cyclin and CBS domain divalent metal cation transport mediator 4b
chr14_-_21660548 3.05 ENSDART00000161713
ENSDART00000089845
lysine (K)-specific demethylase 3B
chr15_-_37104165 3.05 ENSDART00000165867
zmp:0000001114
chr21_-_25295087 3.04 ENSDART00000087910
ENSDART00000147860
suppression of tumorigenicity 14 (colon carcinoma) b
chr15_+_23657051 3.02 ENSDART00000078336
kinesin light chain 3
chr20_+_26940178 3.02 ENSDART00000190888
cell division cycle associated 4
chr13_-_18011168 2.98 ENSDART00000144813
membrane-associated ring finger (C3HC4) 8
chr3_-_2623176 2.96 ENSDART00000179792
ENSDART00000123512
si:dkey-217f16.6
chr1_-_55015439 2.95 ENSDART00000161029
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr7_+_38808027 2.90 ENSDART00000052323
harbinger transposase derived 1
chr24_-_23716097 2.86 ENSDART00000084954
ENSDART00000129028
phosphatidylinositol glycan anchor biosynthesis, class N
chr2_-_57110477 2.86 ENSDART00000181132
solute carrier family 25, member 42
chr5_-_48070779 2.85 ENSDART00000078401
transmembrane protein 161B
chr7_-_55633475 2.85 ENSDART00000149478
galactosamine (N-acetyl)-6-sulfatase
chr10_+_3428194 2.82 ENSDART00000081599
protein tyrosine phosphatase, non-receptor type 11, a
chr5_-_3960161 2.80 ENSDART00000111453
myosin XIX
chr19_-_6193448 2.79 ENSDART00000151405
Ets2 repressor factor
chr25_+_16214854 2.79 ENSDART00000109672
ENSDART00000190093
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr19_-_2822372 2.78 ENSDART00000109130
ENSDART00000122385
RecQ helicase-like 4
chr13_+_5978809 2.75 ENSDART00000102563
ENSDART00000121598
PHD finger protein 10
chr23_+_28378543 2.75 ENSDART00000145327
zgc:153867
chr8_+_30742898 2.74 ENSDART00000018475
small nuclear ribonucleoprotein D3 polypeptide
chr23_-_36670369 2.73 ENSDART00000006881
zinc finger and BTB domain containing 39
chr10_-_15854743 2.73 ENSDART00000092343
tight junction protein 2a (zona occludens 2)
chr12_+_22404108 2.69 ENSDART00000153055
high density lipoprotein binding protein b
chr24_+_36317544 2.67 ENSDART00000048640
ENSDART00000156096
pseudouridylate synthase 3
chr2_-_42492201 2.67 ENSDART00000180762
ENSDART00000009093
extended synaptotagmin-like protein 2a
chr8_-_25566347 2.66 ENSDART00000138289
ENSDART00000078022
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr18_+_38775277 2.66 ENSDART00000186129
family with sequence similarity 214, member A
chr7_-_48251234 2.66 ENSDART00000024062
ENSDART00000098904
cytoplasmic polyadenylation element binding protein 1b
chr19_+_41479990 2.66 ENSDART00000087187
argonaute RISC catalytic component 2
chr6_-_37745508 2.66 ENSDART00000078316
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr2_-_41723487 2.65 ENSDART00000170171
zgc:110158
chr11_+_31864921 2.65 ENSDART00000180252
diaphanous-related formin 3
chr16_+_35924188 2.64 ENSDART00000165847
SH3 domain containing 21
chr1_+_11107688 2.64 ENSDART00000109858
kinetochore-localized astrin/SPAG5 binding protein
chr11_+_506465 2.64 ENSDART00000082519
Raf-1 proto-oncogene, serine/threonine kinase b
chr18_-_40913294 2.63 ENSDART00000059196
ENSDART00000098878
polymerase (RNA) II (DNA directed) polypeptide I
chr2_+_44512324 2.62 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
PAS domain containing serine/threonine kinase
chr7_-_49594995 2.61 ENSDART00000174161
ENSDART00000109147
BR serine/threonine kinase 2b
chr6_+_32393057 2.61 ENSDART00000190765
dedicator of cytokinesis 7
chr7_+_34487833 2.57 ENSDART00000173854
CLN6, transmembrane ER protein a
chr9_+_24088062 2.57 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr2_-_42492445 2.57 ENSDART00000139929
extended synaptotagmin-like protein 2a
chr11_-_43226255 2.56 ENSDART00000172929
spectrin, beta, non-erythrocytic 1
chr2_+_1988036 2.56 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr14_-_36437249 2.55 ENSDART00000016728
aspartylglucosaminidase
chr7_+_21787507 2.55 ENSDART00000100936
transmembrane protein 88 b
chr9_+_38458193 2.55 ENSDART00000008053
minichromosome maintenance complex component 3 associated protein
chr16_-_41488023 2.53 ENSDART00000169312
CKLF-like MARVEL transmembrane domain containing 6
chr25_-_14087377 2.53 ENSDART00000124140
zgc:101566
chr13_+_37653851 2.53 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
PHD finger protein 3
chr13_-_36761379 2.52 ENSDART00000131534
ENSDART00000029824
mitogen-activated protein kinase kinase kinase kinase 5
chr10_-_33251876 2.51 ENSDART00000184565
BCL tumor suppressor 7Ba
chr5_-_49951106 2.51 ENSDART00000135954
family with sequence similarity 172, member A
chr18_+_20047374 2.50 ENSDART00000146957
uveal autoantigen with coiled-coil domains and ankyrin repeats a
chr5_-_22052852 2.48 ENSDART00000002938
myotubularin related protein 8
chr5_+_61361815 2.48 ENSDART00000009507
GATS protein-like 2
chr11_-_24523161 2.46 ENSDART00000191936
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr12_-_28791969 2.46 ENSDART00000153073
oxysterol binding protein-like 7
chr25_-_13789955 2.45 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
cytoskeleton associated protein 5
chr18_+_17534627 2.44 ENSDART00000061007
metallothionein 2
chr8_-_53896982 2.43 ENSDART00000169206
mindbomb E3 ubiquitin protein ligase 2
chr16_+_39146696 2.43 ENSDART00000121756
ENSDART00000084381
syntabulin (syntaxin-interacting)
chr3_+_28502419 2.41 ENSDART00000151081
septin 12
chr3_-_15119856 2.40 ENSDART00000138328
exportin 6
chr20_-_28842524 2.40 ENSDART00000046035
ENSDART00000139843
ENSDART00000129858
ENSDART00000137425
ENSDART00000135720
myc associated factor X
chr3_-_55650771 2.40 ENSDART00000162413
axin 2 (conductin, axil)
chr22_-_38934989 2.39 ENSDART00000008365
nuclear cap binding protein subunit 2
chr2_+_44518636 2.39 ENSDART00000153733
PAS domain containing serine/threonine kinase
chr1_-_40519340 2.38 ENSDART00000114659
mastermind-like transcriptional coactivator 3
chr22_-_17688868 2.38 ENSDART00000012336
ENSDART00000147070
tight junction protein 3
chr17_-_23709347 2.37 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr16_+_25259313 2.37 ENSDART00000058938
F-box protein 32
chr18_-_21725638 2.36 ENSDART00000089853
FANCD2/FANCI-associated nuclease 1
chr7_+_26549846 2.35 ENSDART00000141353
tyrosine kinase, non-receptor, 1
chr5_-_23517747 2.35 ENSDART00000137655
stromal antigen 2a
chr5_+_44805269 2.34 ENSDART00000136965
cathepsin La
chr10_+_3153973 2.34 ENSDART00000183223
hypermethylated in cancer 2
chr12_-_4301234 2.34 ENSDART00000152377
ENSDART00000152521
carbonic anhydrase XVb
chr14_+_21699129 2.33 ENSDART00000073707
syntaxin 3A
chr15_-_16946124 2.33 ENSDART00000154923
huntingtin interacting protein 1
chr3_-_4501026 2.33 ENSDART00000163052
zgc:162198
chr19_-_12965020 2.32 ENSDART00000128975
solute carrier family 25 (mitochondrial folate carrier), member 32a
chr5_+_44805028 2.32 ENSDART00000141198
cathepsin La
chr1_+_44173245 2.32 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
catenin (cadherin-associated protein), delta 1
chr16_-_35532937 2.31 ENSDART00000193209
CTP synthase 1b
chr9_+_54039006 2.31 ENSDART00000112441
toll-like receptor 7
chr22_-_5171829 2.30 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr8_-_537716 2.29 ENSDART00000051777
zgc:101664
chr23_+_38171186 2.28 ENSDART00000148188
zgc:112994
chr22_-_10752471 2.27 ENSDART00000081191
SAS-6 centriolar assembly protein
chr16_+_47207691 2.27 ENSDART00000062507
islet cell autoantigen 1
chr20_-_23876291 2.27 ENSDART00000043316
katanin p60 (ATPase containing) subunit A 1
chr16_-_31791165 2.27 ENSDART00000148389
chromodomain helicase DNA binding protein 4b
chr22_-_3299100 2.26 ENSDART00000160305
si:zfos-943e10.1
chr4_-_1720648 2.26 ENSDART00000103484
growth arrest-specific 2 like 3
chr6_+_20954400 2.25 ENSDART00000143248
ENSDART00000165806
serine/threonine kinase 11 interacting protein
chr7_+_13830052 2.24 ENSDART00000191360
abhydrolase domain containing 2a
chr3_-_15131438 2.23 ENSDART00000131720
exportin 6
chr23_-_26784736 2.23 ENSDART00000024064
ENSDART00000131615
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr21_+_4116437 2.23 ENSDART00000167791
ENSDART00000123759
Rap guanine nucleotide exchange factor (GEF) 1b
chr7_+_13824150 2.23 ENSDART00000035067
abhydrolase domain containing 2a
chr25_+_7494181 2.22 ENSDART00000165005
catalase
chr1_+_12302073 2.22 ENSDART00000164045
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr16_-_47381519 2.22 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
chr17_-_14966384 2.22 ENSDART00000105064
thioredoxin domain containing 16
chr23_+_4709607 2.21 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr8_+_8643901 2.21 ENSDART00000142076
ENSDART00000075624
ubiquitin specific peptidase 11
chr2_+_30740095 2.21 ENSDART00000186387
transcription elongation factor A (SII), 1
chr18_+_26429428 2.20 ENSDART00000142686
Bloom syndrome, RecQ helicase-like
chr24_+_33462800 2.19 ENSDART00000166666
ENSDART00000050826
regulator of MON1-CCZ1
chr2_+_34967022 2.19 ENSDART00000134926
astrotactin 1
chr3_+_31662126 2.19 ENSDART00000113441
myosin, light chain kinase 5
chr13_-_23051766 2.19 ENSDART00000111774
SUV3-like helicase
chr17_+_50261603 2.18 ENSDART00000154503
ENSDART00000154467
synaptotagmin binding, cytoplasmic RNA interacting protein, like
chr1_+_26676758 2.18 ENSDART00000152299
si:dkey-25o16.4
chr4_+_14981854 2.18 ENSDART00000067046
cation/H+ exchanger protein 1
chr10_-_44017642 2.18 ENSDART00000135240
ENSDART00000014669
acyl-CoA dehydrogenase short chain
chr8_+_42917515 2.17 ENSDART00000021715
solute carrier family 23 (ascorbic acid transporter), member 2
chr11_-_38554394 2.16 ENSDART00000102858
nuclear casein kinase and cyclin-dependent kinase substrate 1a
chr21_-_30082414 2.15 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr17_-_29311835 2.14 ENSDART00000104224
tectonin beta-propeller repeat containing 2
chr3_+_31925067 2.14 ENSDART00000127330
ENSDART00000055279
small nuclear ribonucleoprotein 70 (U1)
chr7_-_32629458 2.13 ENSDART00000001376
ADP-ribosylation factor-like 14 effector protein
chr25_+_28158352 2.13 ENSDART00000151854
Ca++-dependent secretion activator 2
chr9_-_30220818 2.13 ENSDART00000140929
si:dkey-100n23.3
chr17_-_29271359 2.12 ENSDART00000104219
REST corepressor 1
chr19_-_6983002 2.11 ENSDART00000104891
zinc finger protein 384 like
chr13_-_12667220 2.10 ENSDART00000079594
family with sequence similarity 241 member A

Network of associatons between targets according to the STRING database.

First level regulatory network of foxd3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.9 9.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.6 4.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
1.4 4.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
1.2 3.7 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
1.1 4.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.1 3.2 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
1.0 5.2 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
1.0 3.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
1.0 3.1 GO:0071896 protein localization to adherens junction(GO:0071896)
1.0 4.0 GO:0042308 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
1.0 4.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.0 3.8 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.9 4.5 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.8 4.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.8 2.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.8 3.2 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.8 2.4 GO:0046833 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.8 3.9 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.8 4.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.8 2.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.8 2.3 GO:0045830 regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.7 3.0 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.7 3.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.7 4.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.7 5.5 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.7 2.0 GO:0034214 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.7 6.0 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.7 2.0 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.7 2.0 GO:1905072 cardiac jelly development(GO:1905072)
0.6 1.9 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.6 3.7 GO:0016559 peroxisome fission(GO:0016559)
0.6 2.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.6 2.4 GO:0060074 synapse maturation(GO:0060074)
0.6 5.8 GO:0030104 water homeostasis(GO:0030104)
0.6 2.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.6 5.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.5 1.6 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.5 2.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.5 1.6 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.5 4.3 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.5 2.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.5 2.7 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.5 2.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.5 1.6 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.5 6.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.5 2.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.5 3.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.5 1.0 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.5 2.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.5 3.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.5 1.4 GO:0032570 response to progesterone(GO:0032570)
0.5 3.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.5 1.4 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.4 1.3 GO:2000402 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.4 1.7 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.4 2.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.4 1.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.4 4.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.4 0.4 GO:1903430 negative regulation of cell maturation(GO:1903430)
0.4 1.6 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.4 1.6 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.4 1.2 GO:1900274 positive regulation of phospholipase C activity(GO:0010863) regulation of phospholipase C activity(GO:1900274)
0.4 7.5 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.4 1.2 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.4 2.0 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 3.1 GO:0051013 microtubule severing(GO:0051013)
0.4 1.1 GO:1905133 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.4 1.5 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.4 1.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.4 2.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 2.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.4 6.1 GO:0015693 magnesium ion transport(GO:0015693)
0.4 1.8 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.4 3.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 1.0 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 1.0 GO:0051026 chiasma assembly(GO:0051026)
0.3 1.0 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.3 1.0 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.3 2.3 GO:0040016 embryonic cleavage(GO:0040016)
0.3 1.6 GO:0002159 desmosome assembly(GO:0002159)
0.3 1.3 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.3 5.3 GO:0051764 actin crosslink formation(GO:0051764)
0.3 2.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.3 4.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.3 1.8 GO:0032964 collagen biosynthetic process(GO:0032964)
0.3 2.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.3 2.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 3.6 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.3 1.5 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.3 1.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.3 1.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.3 1.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.3 1.7 GO:0016578 histone deubiquitination(GO:0016578)
0.3 3.1 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.3 2.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.3 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.3 1.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.3 3.9 GO:0010574 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575)
0.3 1.8 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.3 0.8 GO:1903646 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.3 2.6 GO:0006517 protein deglycosylation(GO:0006517)
0.3 2.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 1.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 8.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 1.7 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.2 1.9 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.2 2.8 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 2.4 GO:0006108 malate metabolic process(GO:0006108)
0.2 2.4 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.2 0.7 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.2 2.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 2.2 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.2 1.5 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.2 1.5 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.2 0.9 GO:0070084 protein initiator methionine removal(GO:0070084)
0.2 1.9 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.2 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 4.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.2 1.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 2.8 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 0.6 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.2 1.8 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 1.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 1.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 1.0 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 6.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 4.0 GO:0007520 myoblast fusion(GO:0007520)
0.2 1.3 GO:1902902 negative regulation of autophagosome maturation(GO:1901097) negative regulation of autophagosome assembly(GO:1902902)
0.2 3.2 GO:0008354 germ cell migration(GO:0008354)
0.2 3.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.2 1.4 GO:0044211 CTP salvage(GO:0044211)
0.2 0.9 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.2 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.2 1.5 GO:0007220 Notch receptor processing(GO:0007220)
0.2 14.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.2 1.5 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 0.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.0 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.2 2.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 0.6 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.2 2.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.2 5.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 2.3 GO:0019985 translesion synthesis(GO:0019985)
0.2 2.3 GO:0045116 protein neddylation(GO:0045116) positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.2 1.2 GO:0021634 optic nerve formation(GO:0021634)
0.2 2.3 GO:0051310 metaphase plate congression(GO:0051310)
0.2 2.1 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.1 1.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.9 GO:0016048 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.1 2.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.9 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.4 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 1.9 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 1.3 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.1 0.6 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.3 GO:0070228 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.1 1.4 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 2.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.8 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 2.9 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 1.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 4.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 1.3 GO:0051601 exocyst localization(GO:0051601)
0.1 2.1 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.5 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 2.2 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.1 2.7 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 1.9 GO:0090279 regulation of calcium ion import(GO:0090279)
0.1 1.9 GO:0048922 posterior lateral line neuromast deposition(GO:0048922) regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 2.9 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 1.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 4.4 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 5.6 GO:0003146 heart jogging(GO:0003146)
0.1 2.0 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 2.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 2.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.6 GO:0002431 Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1 2.2 GO:0048264 determination of ventral identity(GO:0048264)
0.1 2.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 2.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.3 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 2.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.9 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.1 0.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.7 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 0.5 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 2.0 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.5 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.8 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 3.9 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.7 GO:0045109 intermediate filament organization(GO:0045109) intermediate filament bundle assembly(GO:0045110)
0.1 1.7 GO:0034032 nucleoside bisphosphate metabolic process(GO:0033865) ribonucleoside bisphosphate metabolic process(GO:0033875) purine nucleoside bisphosphate metabolic process(GO:0034032)
0.1 0.6 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 2.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.0 GO:0042407 cristae formation(GO:0042407)
0.1 1.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.9 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 1.6 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.9 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.9 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 1.8 GO:0060173 limb development(GO:0060173)
0.1 1.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.4 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 1.8 GO:0001966 thigmotaxis(GO:0001966)
0.1 1.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.7 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 6.6 GO:0090504 epiboly(GO:0090504)
0.1 0.9 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.6 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.3 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 4.3 GO:0051693 actin filament capping(GO:0051693)
0.1 0.2 GO:0002076 osteoblast development(GO:0002076)
0.1 0.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 1.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.6 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.5 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 2.1 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 2.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 2.1 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 2.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 0.7 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 2.7 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.1 0.1 GO:0051099 positive regulation of DNA binding(GO:0043388) positive regulation of binding(GO:0051099) regulation of DNA binding(GO:0051101)
0.1 1.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 3.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 0.2 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.1 3.8 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.1 1.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.5 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.4 GO:0009584 detection of visible light(GO:0009584)
0.1 0.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 0.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.8 GO:0043244 regulation of protein complex disassembly(GO:0043244)
0.0 0.5 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109) regulation of adherens junction organization(GO:1903391)
0.0 1.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 6.7 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 2.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0071543 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 2.3 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 1.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.4 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.6 GO:0043507 activation of JUN kinase activity(GO:0007257) regulation of JUN kinase activity(GO:0043506) positive regulation of JUN kinase activity(GO:0043507)
0.0 1.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 2.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.4 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.9 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.8 GO:0072666 establishment of protein localization to vacuole(GO:0072666)
0.0 2.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.7 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:1900027 regulation of ruffle assembly(GO:1900027) positive regulation of ruffle assembly(GO:1900029)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 2.4 GO:0016573 histone acetylation(GO:0016573)
0.0 1.0 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.0 0.5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.9 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.8 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.7 GO:0048538 thymus development(GO:0048538)
0.0 0.6 GO:0043486 histone exchange(GO:0043486)
0.0 0.7 GO:0014029 neural crest formation(GO:0014029)
0.0 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.0 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 1.5 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.5 GO:0043113 receptor clustering(GO:0043113)
0.0 0.6 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.0 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.8 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.0 0.8 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.5 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 1.4 GO:0006909 phagocytosis(GO:0006909)
0.0 4.9 GO:0006869 lipid transport(GO:0006869)
0.0 3.5 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649) entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.4 GO:0048794 swim bladder development(GO:0048794)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 1.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 1.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 8.9 GO:0030029 actin filament-based process(GO:0030029)
0.0 0.0 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.0 0.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.0 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.3 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.4 GO:0000910 cytokinesis(GO:0000910) regulation of cytokinesis(GO:0032465)
0.0 0.1 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 1.4 GO:0008033 tRNA processing(GO:0008033)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.6 GO:0070390 transcription export complex 2(GO:0070390)
1.1 4.5 GO:0097524 sperm plasma membrane(GO:0097524)
1.0 4.0 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.8 10.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.8 2.3 GO:0098536 deuterosome(GO:0098536)
0.7 3.0 GO:0035339 SPOTS complex(GO:0035339)
0.7 5.0 GO:0034518 RNA cap binding complex(GO:0034518)
0.7 2.9 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.6 1.9 GO:0031213 RSF complex(GO:0031213)
0.6 1.8 GO:0030686 90S preribosome(GO:0030686)
0.6 2.3 GO:0097268 cytoophidium(GO:0097268)
0.5 3.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.5 2.6 GO:0008091 spectrin(GO:0008091)
0.5 2.0 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.5 2.9 GO:0000938 GARP complex(GO:0000938)
0.5 3.8 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.5 3.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4 2.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 2.4 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.4 9.3 GO:0071141 SMAD protein complex(GO:0071141)
0.4 0.7 GO:1990745 EARP complex(GO:1990745)
0.4 1.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 1.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 3.6 GO:0034451 centriolar satellite(GO:0034451)
0.3 2.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.3 1.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.3 1.2 GO:0032584 growth cone membrane(GO:0032584)
0.3 2.7 GO:0089701 U2AF(GO:0089701)
0.3 11.0 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.3 1.7 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.3 3.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 2.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 3.8 GO:0002102 podosome(GO:0002102)
0.3 2.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 0.8 GO:0072380 TRC complex(GO:0072380)
0.2 1.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 3.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 2.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 3.6 GO:0070187 telosome(GO:0070187)
0.2 1.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 3.2 GO:0048179 activin receptor complex(GO:0048179)
0.2 3.6 GO:0071564 npBAF complex(GO:0071564)
0.2 2.8 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.2 2.4 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.2 5.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 1.7 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2 3.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 8.2 GO:0030496 midbody(GO:0030496)
0.2 1.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 11.3 GO:0031901 early endosome membrane(GO:0031901)
0.2 21.3 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.2 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.5 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.0 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.1 1.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 8.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.7 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.5 GO:0035101 FACT complex(GO:0035101)
0.1 1.8 GO:0042555 MCM complex(GO:0042555)
0.1 2.3 GO:0030057 desmosome(GO:0030057)
0.1 0.5 GO:0016460 myosin II complex(GO:0016460)
0.1 2.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.0 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.7 GO:0030914 STAGA complex(GO:0030914)
0.1 0.7 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 3.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 5.0 GO:0031941 filamentous actin(GO:0031941)
0.1 1.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.0 GO:0000812 Swr1 complex(GO:0000812)
0.1 2.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.0 GO:0005685 U1 snRNP(GO:0005685)
0.1 24.8 GO:0005764 lysosome(GO:0005764)
0.1 7.9 GO:0005871 kinesin complex(GO:0005871)
0.1 5.3 GO:0030139 endocytic vesicle(GO:0030139)
0.1 5.9 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.0 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.9 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 7.3 GO:0030027 lamellipodium(GO:0030027)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 4.8 GO:0000793 condensed chromosome(GO:0000793)
0.1 1.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 15.8 GO:0005813 centrosome(GO:0005813)
0.1 8.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 0.6 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 3.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 2.0 GO:0016605 PML body(GO:0016605)
0.1 1.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 15.4 GO:0005730 nucleolus(GO:0005730)
0.1 5.0 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0000145 exocyst(GO:0000145)
0.0 2.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.0 GO:0016342 catenin complex(GO:0016342)
0.0 1.4 GO:0005844 polysome(GO:0005844)
0.0 2.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 4.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 4.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.5 GO:0005903 brush border(GO:0005903)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 2.0 GO:0005769 early endosome(GO:0005769)
0.0 2.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.7 GO:0030135 coated vesicle(GO:0030135)
0.0 0.5 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.5 GO:0005884 actin filament(GO:0005884)
0.0 1.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 2.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 4.4 GO:0005768 endosome(GO:0005768)
0.0 0.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.1 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 9.4 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.6 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
2.0 10.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.2 6.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.0 5.2 GO:0035197 siRNA binding(GO:0035197)
1.0 2.9 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.8 2.4 GO:0070336 flap-structured DNA binding(GO:0070336)
0.8 2.3 GO:0008517 folic acid transporter activity(GO:0008517) FAD transmembrane transporter activity(GO:0015230)
0.7 4.5 GO:0008126 acetylesterase activity(GO:0008126)
0.7 2.2 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.7 2.9 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.7 6.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.6 1.8 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.6 2.4 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.6 2.4 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.6 1.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 2.3 GO:0003883 CTP synthase activity(GO:0003883)
0.6 4.5 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.6 5.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.5 3.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.5 2.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.5 2.0 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.5 3.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.5 3.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.5 3.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.4 2.5 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.4 4.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.4 2.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.4 1.6 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.4 1.2 GO:0043621 protein self-association(GO:0043621)
0.4 3.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 6.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.4 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 4.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 1.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 6.9 GO:0070411 I-SMAD binding(GO:0070411)
0.3 5.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 1.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 1.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.3 6.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 6.5 GO:0017136 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
0.3 1.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 1.5 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.3 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.3 2.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.3 2.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 6.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.3 2.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.3 2.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 2.7 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 2.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3 3.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 2.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 2.2 GO:0004096 catalase activity(GO:0004096)
0.2 1.5 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.2 0.9 GO:0030626 U12 snRNA binding(GO:0030626) pre-mRNA intronic binding(GO:0097157)
0.2 1.5 GO:0035173 histone kinase activity(GO:0035173)
0.2 3.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 3.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 2.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 4.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 3.7 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 1.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 0.6 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 2.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 4.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2 1.4 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.4 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.9 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 0.9 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 3.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 2.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 1.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 3.0 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 1.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.7 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 1.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 2.4 GO:0019894 kinesin binding(GO:0019894)
0.1 1.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 3.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.5 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 2.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.1 0.5 GO:0032028 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 3.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 3.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 2.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.1 2.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 15.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.6 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.1 2.0 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.4 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.3 GO:0002039 p53 binding(GO:0002039)
0.1 2.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 18.4 GO:0042393 histone binding(GO:0042393)
0.1 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.6 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 1.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.3 GO:2001070 starch binding(GO:2001070)
0.1 4.2 GO:0017124 SH3 domain binding(GO:0017124)
0.1 3.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 6.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 3.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.9 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 3.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 1.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 3.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 13.9 GO:0042802 identical protein binding(GO:0042802)
0.1 0.6 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 3.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.2 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.0 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 8.5 GO:0060090 binding, bridging(GO:0060090)
0.1 0.2 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.1 1.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 3.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 2.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 11.1 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.9 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.6 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 16.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 3.6 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 1.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 6.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.0 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.5 GO:0002020 protease binding(GO:0002020)
0.0 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 6.3 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 6.1 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 3.2 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 4.5 GO:0008083 growth factor activity(GO:0008083)
0.0 3.6 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.5 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 1.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 1.2 GO:0015296 anion:cation symporter activity(GO:0015296)
0.0 1.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 1.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 5.0 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.0 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 5.7 GO:0003779 actin binding(GO:0003779)
0.0 0.4 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 4.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.3 4.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 9.3 PID AURORA B PATHWAY Aurora B signaling
0.2 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 1.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 12.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 3.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 4.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 4.5 PID CDC42 PATHWAY CDC42 signaling events
0.1 3.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 0.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 5.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 3.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 2.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 5.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 2.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.4 PID FOXO PATHWAY FoxO family signaling
0.1 1.8 PID AURORA A PATHWAY Aurora A signaling
0.1 2.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.0 PID ARF 3PATHWAY Arf1 pathway
0.1 5.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.5 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.7 PID BMP PATHWAY BMP receptor signaling
0.1 2.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 1.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 1.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID EPO PATHWAY EPO signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.5 4.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.4 6.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.4 2.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 4.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4 4.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3 2.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 4.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 4.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.3 5.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 6.3 REACTOME KINESINS Genes involved in Kinesins
0.3 3.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 4.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 3.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 4.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 2.4 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.2 4.3 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.2 1.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 1.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 5.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 2.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.2 2.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 1.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 8.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 2.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 1.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 8.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 5.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 1.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 2.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.5 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases