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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxc1a+foxc1b

Z-value: 0.78

Motif logo

Transcription factors associated with foxc1a+foxc1b

Gene Symbol Gene ID Gene Info
ENSDARG00000055398 forkhead box C1b
ENSDARG00000091481 forkhead box C1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxc1adr11_v1_chr2_-_689047_6890470.971.3e-11Click!
foxc1bdr11_v1_chr20_+_26702377_267023770.978.9e-11Click!

Activity profile of foxc1a+foxc1b motif

Sorted Z-values of foxc1a+foxc1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_34141935 2.71 ENSDART00000127063
family with sequence similarity 183, member A
chr2_+_49644803 2.69 ENSDART00000160342
si:ch211-209f23.7
chr10_+_2587234 2.49 ENSDART00000126937
wu:fb59d01
chr16_-_31974482 2.37 ENSDART00000189073
serine/threonine/tyrosine kinase 1
chr8_+_47817454 2.23 ENSDART00000144825
Pim proto-oncogene, serine/threonine kinase, related 185
chr13_-_10727550 2.18 ENSDART00000190925
protein phosphatase, Mg2+/Mn2+ dependent, 1Ba
chr16_+_28727383 1.95 ENSDART00000149753
DC-STAMP domain containing 2
chr9_-_48736388 1.88 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr4_-_25064510 1.73 ENSDART00000025153
GATA binding protein 3
chr16_-_24815091 1.69 ENSDART00000154269
ENSDART00000131025
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr16_-_13818061 1.68 ENSDART00000132982
ENSDART00000144856
leukocyte receptor cluster (LRC) member 9
chr18_+_25752592 1.60 ENSDART00000111767
si:ch211-39k3.2
chr3_-_18030938 1.59 ENSDART00000013540
si:ch73-141c7.1
chr7_-_16598212 1.49 ENSDART00000128488
E2F transcription factor 8
chr3_-_43770876 1.49 ENSDART00000160162
zgc:92162
chr8_-_48770163 1.39 ENSDART00000160959
Pim proto-oncogene, serine/threonine kinase, related 184
chr22_+_26793389 1.37 ENSDART00000165381
Pim proto-oncogene, serine/threonine kinase, related 69
chr11_-_38910527 1.36 ENSDART00000143105
Pim proto-oncogene, serine/threonine kinase, related 126
chr2_-_24554416 1.32 ENSDART00000052061
calponin 2
chr7_+_49695904 1.31 ENSDART00000183550
ENSDART00000126991
achaete-scute family bHLH transcription factor 1b
chr17_+_53250802 1.29 ENSDART00000143819
vasohibin 1
chr22_+_20720808 1.27 ENSDART00000171321
si:dkey-211f22.5
chr23_-_42752387 1.26 ENSDART00000149781
si:ch73-217n20.1
chr19_-_33370271 1.20 ENSDART00000132628
naked cuticle homolog 3, like
chr21_+_6556635 1.17 ENSDART00000139598
procollagen, type V, alpha 1
chr16_+_7662609 1.16 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
blood vessel epicardial substance
chr3_-_16227683 1.14 ENSDART00000111707
calcium channel, voltage-dependent, beta 1 subunit
chr2_+_6181383 1.07 ENSDART00000153307
si:ch73-344o19.1
chr3_-_16227490 0.96 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
calcium channel, voltage-dependent, beta 1 subunit
chr2_-_31614277 0.94 ENSDART00000137054
ENSDART00000131507
ENSDART00000137674
ENSDART00000147041
si:ch211-106h4.5
chr21_-_22114625 0.93 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr8_-_13471916 0.91 ENSDART00000146558
Pim proto-oncogene, serine/threonine kinase, related 105
chr19_-_19339285 0.86 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr1_-_25679339 0.85 ENSDART00000161703
ENSDART00000054230
fibrinogen gamma chain
chr4_+_12358822 0.81 ENSDART00000172557
ENSDART00000150627
Pim proto-oncogene, serine/threonine kinase, related 168
chr14_-_46310204 0.80 ENSDART00000188713
ENSDART00000184930
crystallin, beta B1, like 1
chr20_+_51478939 0.80 ENSDART00000149758
toll-like receptor 5a
chr25_+_16601839 0.80 ENSDART00000008986
ATPase H+ transporting V1 subunit E1a
chr1_-_9109699 0.79 ENSDART00000147833
vascular associated protein
chr4_+_12342173 0.79 ENSDART00000161518
Pim proto-oncogene, serine/threonine kinase, related 214
chr12_+_695619 0.78 ENSDART00000161691
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr22_+_38978084 0.73 ENSDART00000025482
Rho guanine nucleotide exchange factor (GEF) 3
chr15_-_20468302 0.70 ENSDART00000018514
deltaC
chr11_-_45138857 0.69 ENSDART00000166501
calcium activated nucleotidase 1b
chr19_-_26736336 0.68 ENSDART00000109258
ENSDART00000182802
casein kinase 2, beta polypeptide
chr7_+_23907692 0.66 ENSDART00000045479
synaptotagmin IV
chr24_+_9372292 0.66 ENSDART00000082422
ENSDART00000191127
ENSDART00000180510
si:ch211-285f17.1
chr1_-_54947592 0.66 ENSDART00000129710
cartilage acidic protein 1a
chr1_-_17663108 0.66 ENSDART00000131559
si:dkey-256e7.5
chr8_-_13419049 0.66 ENSDART00000133656
Pim proto-oncogene, serine/threonine kinase, related 101
chr15_+_47903864 0.64 ENSDART00000063835
orthodenticle homolog 5
chr22_-_23000815 0.63 ENSDART00000137111
protein tyrosine phosphatase, receptor type, C
chr17_+_12265095 0.63 ENSDART00000153812
Pim proto-oncogene, serine/threonine kinase, related 168
chr19_-_10730488 0.61 ENSDART00000126033
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 1
chr23_+_18944388 0.60 ENSDART00000104487
cytochrome c oxidase subunit IV isoform 2
chr11_+_583142 0.60 ENSDART00000168157
MKRN2 opposite strand, tandem duplicate 2
chr3_+_26064091 0.60 ENSDART00000143697
si:dkeyp-69e1.8
chr7_-_22132265 0.60 ENSDART00000125284
ENSDART00000112978
neuroligin 2a
chr5_-_28029558 0.60 ENSDART00000078649
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr21_-_17290941 0.59 ENSDART00000147993
growth factor independent 1B transcription repressor
chr11_+_39135050 0.59 ENSDART00000180571
ENSDART00000189685
cell division cycle 42
chr1_-_46326156 0.58 ENSDART00000040284
ATPase phospholipid transporting 11A
chr10_+_38512270 0.56 ENSDART00000109752
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr4_-_14899113 0.54 ENSDART00000137829
si:dkey-14k9.3
chr13_+_28417297 0.54 ENSDART00000043658
solute carrier family 2 (facilitated glucose transporter), member 15a
chr7_+_20030888 0.53 ENSDART00000192808
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr11_+_16138065 0.53 ENSDART00000188616
Pim proto-oncogene, serine/threonine kinase, related 204
chr20_+_51479263 0.53 ENSDART00000148798
toll-like receptor 5a
chr13_+_36680564 0.51 ENSDART00000136030
ENSDART00000006923
ATP synthase, H+ transporting, mitochondrial F0 complex subunit s
chr6_+_9398074 0.50 ENSDART00000151772
kalirin RhoGEF kinase b
chr12_-_24060358 0.50 ENSDART00000050831
ChaC, cation transport regulator homolog 2 (E. coli)
chr22_-_26175237 0.50 ENSDART00000108737
complement component c3b, tandem duplicate 2
chr5_+_30680804 0.50 ENSDART00000078049
PDZ domain containing 3b
chr16_-_1709328 0.49 ENSDART00000168865
activating signal cointegrator 1 complex subunit 3
chr4_+_12333168 0.49 ENSDART00000172455
ENSDART00000146166
Pim proto-oncogene, serine/threonine kinase, related 214
Pim proto-oncogene, serine/threonine kinase, related 171
chr17_-_17764801 0.49 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr16_-_5721386 0.48 ENSDART00000136655
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr11_-_11331052 0.48 ENSDART00000081765
ENSDART00000160247
mitochondrial ribosomal protein L4
chr20_+_38276690 0.48 ENSDART00000061437
chemokine (C-C motif) ligand 38, duplicate 6
chr11_+_11200550 0.47 ENSDART00000181339
ENSDART00000187116
myomesin 2a
chr2_-_9816492 0.47 ENSDART00000138472
ENSDART00000124051
adaptor-related protein complex 2, mu 1 subunit, b
chr19_-_5103313 0.47 ENSDART00000037007
triosephosphate isomerase 1a
chr17_-_53439866 0.47 ENSDART00000154826
c-myc binding protein
chr18_-_41219790 0.46 ENSDART00000162387
ENSDART00000193753
zinc finger and BTB domain containing 38
chr20_-_48061351 0.45 ENSDART00000164962
prolyl endopeptidase
chr5_+_61941610 0.45 ENSDART00000168808
si:dkeyp-117b8.4
chr21_-_22928214 0.45 ENSDART00000182760
duboraya
chr21_-_4918735 0.45 ENSDART00000150936
potassium channel, subfamily T, member 1
chr4_-_73299225 0.45 ENSDART00000174178
ENSDART00000174198
si:cabz01021430.2
chr3_+_25825043 0.43 ENSDART00000153749
phosphoinositide-3-kinase, regulatory subunit 6b
chr14_-_2602445 0.42 ENSDART00000166910
eukaryotic translation termination factor 1a
chr19_+_164013 0.42 ENSDART00000167379
capping protein regulator and myosin 1 linker 1
chr9_+_51180508 0.41 ENSDART00000138990
interferon induced with helicase C domain 1
chr5_-_61431809 0.41 ENSDART00000082952
RCC1 like
chr7_+_9981757 0.41 ENSDART00000113429
ENSDART00000173233
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr20_+_10723292 0.40 ENSDART00000152805
si:ch211-182e10.4
chr4_+_57093908 0.40 ENSDART00000170198
si:ch211-238e22.5
chr6_-_10828880 0.39 ENSDART00000131458
ENSDART00000020261
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr25_-_3087556 0.39 ENSDART00000193249
bestrophin 1
chr6_+_18441331 0.39 ENSDART00000171005
si:dkey-31g6.4
chr23_+_25893020 0.39 ENSDART00000144769
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_-_22338521 0.39 ENSDART00000176849
si:ch73-380n15.2
chr9_+_13985567 0.37 ENSDART00000102296
CD28 molecule
chr3_-_1938588 0.37 ENSDART00000013001
ENSDART00000186405
zgc:152753
chr1_-_14332283 0.37 ENSDART00000090025
Wolfram syndrome 1a (wolframin)
chr1_+_7540978 0.35 ENSDART00000147770
myosin, light polypeptide 3, skeletal muscle
chr13_-_47800342 0.35 ENSDART00000121817
fibulin 7
chr10_-_302827 0.34 ENSDART00000157582
EMSY BRCA2-interacting transcriptional repressor
chr21_-_2310064 0.33 ENSDART00000169520
si:ch211-241b2.1
chr21_-_43606502 0.31 ENSDART00000151030
si:ch73-362m14.4
chr8_-_44015210 0.31 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
RIMS binding protein 2
RIMS binding protein 2
chr8_-_46525092 0.31 ENSDART00000030482
sulfotransferase family 1, cytosolic sulfotransferase 2
chr23_-_15090782 0.30 ENSDART00000133624
si:ch211-218g4.2
chr9_-_370225 0.30 ENSDART00000163637
si:dkey-11f4.7
chr17_+_45404758 0.29 ENSDART00000147557
T cell activation RhoGTPase activating protein a
chr7_-_28463106 0.29 ENSDART00000137799
tripartite motif containing 66
chr23_+_16910071 0.29 ENSDART00000104793
si:dkey-147f3.8
chr2_-_50372467 0.28 ENSDART00000108900
contactin associated protein like 2b
chr8_+_53464216 0.28 ENSDART00000169514
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr17_-_50430817 0.28 ENSDART00000154007
si:ch211-235i11.4
chr21_-_26250744 0.28 ENSDART00000044735
glutamate receptor, ionotropic, AMPA 1b
chr25_-_31953516 0.28 ENSDART00000110180
dual oxidase 2
chr16_+_9726038 0.28 ENSDART00000192988
ENSDART00000020859
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr25_+_3525494 0.27 ENSDART00000169775
RAB19, member RAS oncogene family
chr6_-_8480815 0.27 ENSDART00000162300
RAS protein activator like 3
chr12_-_31794908 0.27 ENSDART00000105583
ENSDART00000153449
N-acetyltransferase 9 (GCN5-related, putative)
chr18_+_808911 0.27 ENSDART00000172518
cytochrome c oxidase subunit Vab
chr18_+_16986903 0.26 ENSDART00000142088
si:ch211-218c6.8
chr17_-_28097760 0.26 ENSDART00000149861
lysine (K)-specific demethylase 1a
chr9_-_21918963 0.25 ENSDART00000090782
LIM domain 7a
chr21_-_4032650 0.25 ENSDART00000151648
netrin g2b
chr18_+_17754510 0.25 ENSDART00000189372
ENSDART00000135236
ENSDART00000137239
si:ch211-216l23.2
chr1_+_31638274 0.25 ENSDART00000057885
fibroblast growth factor 8 b
chr5_-_54300725 0.24 ENSDART00000163048
solute carrier family 25, member 35
chr13_+_46927350 0.24 ENSDART00000165041
ENSDART00000167931
mitochondrial translational release factor 1-like
chr17_-_12336987 0.23 ENSDART00000172001
synaptosomal-associated protein, 25b
chr5_+_39087364 0.23 ENSDART00000004286
annexin A3a
chr5_+_31860043 0.23 ENSDART00000036235
ENSDART00000140541
iron-sulfur cluster assembly enzyme b
chr12_-_9438227 0.23 ENSDART00000003932
erb-b2 receptor tyrosine kinase 2
chr24_-_40726073 0.22 ENSDART00000168100
slow myosin heavy chain 2
chr20_+_28960340 0.22 ENSDART00000147917
G protein-coupled receptor 176
chr7_-_17337233 0.22 ENSDART00000050236
ENSDART00000102141
novel immune-type receptor 8
chr24_-_10917243 0.22 ENSDART00000144372
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr1_+_44911405 0.22 ENSDART00000182465
wu:fc21g02
chr10_+_17714866 0.21 ENSDART00000039969
solute carrier family 20 (phosphate transporter), member 1b
chr9_-_24244383 0.21 ENSDART00000182407
caveolae associated protein 2a
chr15_-_568645 0.21 ENSDART00000156744
cerebellin 18
chr7_-_43787616 0.21 ENSDART00000179758
cadherin 11, type 2, OB-cadherin (osteoblast)
chr16_-_42004544 0.20 ENSDART00000034544
caspase a
chr9_-_32659805 0.20 ENSDART00000141482
granzyme 3, tandem duplicate 2
chr9_-_7421135 0.19 ENSDART00000144600
bridging integrator 1a
chr15_-_1590858 0.19 ENSDART00000081875
nanor
chr4_-_5317006 0.19 ENSDART00000150867
si:ch211-214j24.15
chr8_-_18200003 0.18 ENSDART00000080014
ribosomal protein S8b
chr2_+_56139941 0.18 ENSDART00000164741
pyroglutamyl-peptidase I
chr15_+_638457 0.18 ENSDART00000157162
zinc finger protein 1013
chr12_+_29236274 0.18 ENSDART00000006505
mix-type homeobox gene 2
chr1_-_37383741 0.18 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
secretory calcium-binding phosphoprotein 1
chr15_-_3976035 0.18 ENSDART00000168061
si:ch73-309g22.1
chr16_+_38119004 0.18 ENSDART00000132087
pogo transposable element derived with ZNF domain b
chr17_-_23412705 0.18 ENSDART00000126995
si:ch211-149k12.3
chr8_-_15398760 0.17 ENSDART00000162011
ATP/GTP binding protein-like 4
chr11_+_42765963 0.17 ENSDART00000156080
ENSDART00000179888
tudor domain containing 3
chr8_-_51340773 0.17 ENSDART00000060633
KAT8 regulatory NSL complex subunit 3
chr9_-_7257877 0.17 ENSDART00000153514
si:ch211-121j5.4
chr5_-_61942482 0.16 ENSDART00000097338
N-ethylmaleimide-sensitive factor attachment protein, alpha a
chr14_-_44773864 0.16 ENSDART00000158386
si:dkey-109l4.3
chr14_-_38865800 0.16 ENSDART00000173047
glutathione reductase
chr20_-_15062606 0.16 ENSDART00000175585
ENSDART00000135212
proline-rich coiled-coil 2C
chr5_+_23597144 0.16 ENSDART00000143929
ENSDART00000142420
ENSDART00000032909
K(lysine) acetyltransferase 5b
chr22_+_29135846 0.14 ENSDART00000143811
BAI1-associated protein 2-like 2b
chr15_-_18574716 0.14 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr5_-_67629263 0.13 ENSDART00000133753
zinc finger and BTB domain containing 20
chr12_-_22524388 0.13 ENSDART00000020942
sex hormone-binding globulin
chr13_-_50614639 0.13 ENSDART00000170527
ventral expressed homeobox
chr1_-_23274393 0.13 ENSDART00000147800
ENSDART00000130277
ENSDART00000054340
ENSDART00000054338
ribosomal protein L9
chr6_-_51811095 0.13 ENSDART00000161048
proteasome inhibitor subunit 1
chr25_+_20216159 0.12 ENSDART00000048642
troponin T2d, cardiac
chr12_+_20641471 0.12 ENSDART00000133654
calcium binding and coiled-coil domain 2
chr1_-_37383539 0.12 ENSDART00000127579
secretory calcium-binding phosphoprotein 1
chr23_+_24926407 0.11 ENSDART00000137486
kelch-like family member 21
chr13_+_31002658 0.11 ENSDART00000140257
leucine rich repeat containing 18a
chr1_+_45056371 0.11 ENSDART00000073689
ENSDART00000167309
bloodthirsty-related gene family, member 1
chr5_-_4219741 0.11 ENSDART00000100093
si:ch211-283g2.2
chr22_+_15720381 0.10 ENSDART00000128149
family with sequence similarity 32, member A
chr6_+_72040 0.10 ENSDART00000122957
crystallin, gamma M4
chr20_-_19365875 0.10 ENSDART00000063703
ENSDART00000187707
ENSDART00000161065
si:dkey-71h2.2
chr20_-_35578435 0.09 ENSDART00000142444
adhesion G protein-coupled receptor F6
chr12_-_37941733 0.09 ENSDART00000130167

chr20_-_3166168 0.09 ENSDART00000134137
si:ch73-212j7.3
chr18_-_16792561 0.09 ENSDART00000145546
adenosine monophosphate deaminase 3b
chr21_-_30111134 0.09 ENSDART00000014223
solute carrier family 23 (ascorbic acid transporter), member 1
chr2_-_27473645 0.09 ENSDART00000186152

chr16_-_13992646 0.09 ENSDART00000139623
si:dkey-85k15.6
chr9_+_15893093 0.08 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
chr24_-_36271352 0.08 ENSDART00000153682
ENSDART00000155892
si:ch211-40k21.5
chr1_+_18550864 0.08 ENSDART00000142515
si:dkey-192k22.2
chr14_-_22390821 0.08 ENSDART00000054396
F-box and leucine-rich repeat protein 3, like
chr17_-_465285 0.08 ENSDART00000168718
cholinergic receptor, muscarinic 5a
chr15_-_12319065 0.08 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6

Network of associatons between targets according to the STRING database.

First level regulatory network of foxc1a+foxc1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3 1.3 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.2 1.7 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.2 1.2 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.2 1.5 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 0.5 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 1.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.4 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.5 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.7 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.5 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.1 2.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.9 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 0.9 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.6 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:0070126 mitochondrial translational termination(GO:0070126)
0.1 0.4 GO:0032648 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.1 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.8 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.3 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 0.2 GO:0048940 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.1 0.6 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.6 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.6 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 2.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0086009 membrane repolarization(GO:0086009)
0.0 0.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 1.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.0 10.6 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.5 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 1.3 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.6 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.3 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 2.7 GO:0097546 ciliary base(GO:0097546)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.6 GO:0031526 brush border membrane(GO:0031526)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.2 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 2.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.8 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 2.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042166 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.2 1.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 0.6 GO:0046978 TAP1 binding(GO:0046978)
0.2 1.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 1.5 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 1.6 GO:0048039 ubiquinone binding(GO:0048039)
0.2 0.5 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.1 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.5 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 2.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.2 GO:0030552 cAMP binding(GO:0030552)
0.1 0.2 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 2.2 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.6 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 3.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases