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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for etv7
Z-value: 0.81
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Transcription factors associated with etv7
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| etv7 | dr11_v1_chr23_-_5101847_5101847 | 0.21 | 4.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_+_29648854 Show fit | 0.95 |
ENSDART00000146280
|
BBSome interacting protein 1 |
|
| chr5_-_50084310 Show fit | 0.84 |
ENSDART00000074599
ENSDART00000189970 |
family with sequence similarity 172, member A |
|
| chr16_+_6944311 Show fit | 0.82 |
ENSDART00000144763
|
ELL associated factor 1 |
|
| chr5_+_872299 Show fit | 0.82 |
ENSDART00000130042
|
far upstream element (FUSE) binding protein 3 |
|
| chr19_+_9050852 Show fit | 0.77 |
ENSDART00000151031
|
ash1 (absent, small, or homeotic)-like (Drosophila) |
|
| chr16_-_33930759 Show fit | 0.77 |
ENSDART00000177453
|
dynein, axonemal, light intermediate chain 1 |
|
| chr21_+_37513058 Show fit | 0.76 |
ENSDART00000141096
|
angiomotin |
|
| chr2_-_37134169 Show fit | 0.75 |
ENSDART00000146123
ENSDART00000146533 ENSDART00000040427 |
ELAV like RNA binding protein 1a |
|
| chr13_+_9559461 Show fit | 0.75 |
ENSDART00000047740
|
WD repeat domain 32 |
|
| chr19_+_47290287 Show fit | 0.75 |
ENSDART00000078382
|
thiopurine S-methyltransferase, tandem duplicate 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of etv7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | GO:0014812 | muscle cell migration(GO:0014812) |
| 0.3 | 1.0 | GO:1903441 | receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441) |
| 0.1 | 0.9 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.1 | 0.8 | GO:0031048 | chromatin silencing by small RNA(GO:0031048) |
| 0.1 | 0.8 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
| 0.0 | 0.8 | GO:0045766 | positive regulation of angiogenesis(GO:0045766) |
| 0.2 | 0.7 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.0 | 0.7 | GO:0033962 | cytoplasmic mRNA processing body assembly(GO:0033962) |
| 0.0 | 0.7 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.1 | 0.6 | GO:2000576 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.5 | GO:0032783 | ELL-EAF complex(GO:0032783) |
| 0.0 | 1.1 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.1 | 1.0 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.9 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 0.8 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.8 | GO:0030286 | dynein complex(GO:0030286) |
| 0.1 | 0.7 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.1 | 0.7 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.1 | 0.6 | GO:0097134 | cyclin E1-CDK2 complex(GO:0097134) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.5 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 1.0 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.2 | 0.8 | GO:0035197 | siRNA binding(GO:0035197) |
| 0.0 | 0.8 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 0.8 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.0 | 0.8 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
| 0.0 | 0.8 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.2 | 0.7 | GO:0008119 | thiopurine S-methyltransferase activity(GO:0008119) |
| 0.1 | 0.7 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.7 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.5 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.9 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.8 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.7 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.7 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.6 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.5 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.4 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.4 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |