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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

Z-value: 4.19

Transcription factors associated with etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

Gene Symbol Gene ID Gene Info
ENSDARG00000044511 ETS variant transcription factor 5b
ENSDARG00000069763 ETS variant transcription factor 5a
ENSDARG00000113729 ETS variant transcription factor 5a
ENSDARG00000113744 ETS variant transcription factor 5b
ENSDARG00000078066 ETS transcription factor ELK1
ENSDARG00000077092 ETS transcription factor ELK4
ENSDARG00000101959 ETS variant transcription factor 1
ENSDARG00000020759 E74-like ETS transcription factor 1
ENSDARG00000062801 Ets2 repressor factor like 3
ENSDARG00000063417 Ets2 repressor factor
ENSDARG00000069289 GA binding protein transcription factor subunit alpha
ENSDARG00000110923 GA binding protein transcription factor subunit alpha
ENSDARG00000018688 ETS transcription factor ELK3
ENSDARG00000110853 ETS transcription factor ELK3

Activity profile of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3 motif

Sorted Z-values of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_8365398 18.75 ENSDART00000138713
ENSDART00000136847
si:dkey-90l23.2
chr20_-_23253630 17.35 ENSDART00000103365
OCIA domain containing 1
chr1_+_59314675 14.22 ENSDART00000161872
ENSDART00000160658
ENSDART00000169792
ENSDART00000160735
poly(A)-specific ribonuclease (deadenylation nuclease)
chr9_+_8408054 12.89 ENSDART00000144373
zgc:153499
chr1_-_55044256 12.60 ENSDART00000165505
ENSDART00000167536
ENSDART00000170001
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr21_-_30994577 12.14 ENSDART00000065503
post-GPI attachment to proteins 2
chr20_-_10487951 11.99 ENSDART00000064112
glutaredoxin 5 homolog (S. cerevisiae)
chr9_+_426392 11.85 ENSDART00000172515
basic leucine zipper and W2 domains 1b
chr14_-_14687004 11.60 ENSDART00000169970
germ cell nuclear acidic peptidase
chr12_-_10508952 11.22 ENSDART00000152806
zgc:152977
chr24_-_32522587 11.11 ENSDART00000048968
ENSDART00000143781
zgc:56676
chr13_-_35761266 11.07 ENSDART00000190217
endoplasmic reticulum lectin 1
chr25_-_19574146 10.96 ENSDART00000156811
si:ch211-59o9.10
chr3_-_36440705 10.57 ENSDART00000162875
rogdi homolog (Drosophila)
chr13_-_35760969 10.56 ENSDART00000127476
endoplasmic reticulum lectin 1
chr9_-_21238616 10.54 ENSDART00000191840
ENSDART00000189127
COX17 cytochrome c oxidase copper chaperone
chr5_+_3927989 10.37 ENSDART00000030125
zinc finger, HIT-type containing 3
chr13_-_9300299 10.37 ENSDART00000144142
si:dkey-33c12.12
chr3_+_32416948 10.31 ENSDART00000157324
ENSDART00000154267
ENSDART00000186094
ENSDART00000155860
ENSDART00000156986
proline rich Gla (G-carboxyglutamic acid) 2
chr21_+_21743599 10.23 ENSDART00000101700
polymerase (DNA-directed), delta 3, accessory subunit
chr7_+_55518519 10.20 ENSDART00000098476
ENSDART00000149915
chromatin licensing and DNA replication factor 1
chr9_+_8407778 10.15 ENSDART00000102754
ENSDART00000178144
zgc:153499
chr20_+_13141408 10.10 ENSDART00000034098
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr2_-_57900430 9.69 ENSDART00000132245
ENSDART00000140060
si:dkeyp-68b7.7
chr2_+_30182431 9.66 ENSDART00000004903
retinol dehydrogenase 10b
chr17_+_39790388 9.65 ENSDART00000149488
ubiquitin protein ligase E3 component n-recognin 1
chr25_-_36263115 9.24 ENSDART00000143046
ENSDART00000139002
dihydrouridine synthase 2
chr14_+_16083818 9.18 ENSDART00000168462
ring finger protein 103
chr8_+_47683352 9.16 ENSDART00000187320
ENSDART00000192605
dipeptidyl-peptidase 9
chr9_-_12269847 9.15 ENSDART00000136558
ENSDART00000144734
ENSDART00000131766
ENSDART00000032344
nucleoporin 35
chr25_+_186583 9.05 ENSDART00000161504
PCNA clamp associated factor
chr5_-_69482891 8.97 ENSDART00000109487

chr3_-_15131438 8.82 ENSDART00000131720
exportin 6
chr1_+_494297 8.65 ENSDART00000108579
ENSDART00000146732
basic leucine zipper nuclear factor 1
chr9_-_7287128 8.65 ENSDART00000176281
ENSDART00000065803
MIT, microtubule interacting and transport, domain containing 1
chr13_+_9559461 8.50 ENSDART00000047740
WD repeat domain 32
chr17_+_50261603 8.46 ENSDART00000154503
ENSDART00000154467
synaptotagmin binding, cytoplasmic RNA interacting protein, like
chr9_-_7287375 8.44 ENSDART00000128352
MIT, microtubule interacting and transport, domain containing 1
chr9_-_21238159 8.42 ENSDART00000146764
ENSDART00000102143
COX17 cytochrome c oxidase copper chaperone
chr5_+_27404946 8.39 ENSDART00000121886
ENSDART00000005025
hematopoietic death receptor
chr21_-_30181268 8.36 ENSDART00000167867
heterogeneous nuclear ribonucleoprotein H1, like
chr2_+_38055529 8.31 ENSDART00000145642
si:rp71-1g18.1
chr22_-_8306743 8.15 ENSDART00000123982

chr13_-_33700461 8.07 ENSDART00000160520
MAD2L1 binding protein
chr21_-_30181732 7.87 ENSDART00000015636
heterogeneous nuclear ribonucleoprotein H1, like
chr6_+_52212927 7.87 ENSDART00000143458
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr8_+_47677208 7.85 ENSDART00000123254
dipeptidyl-peptidase 9
chr4_-_18606524 7.83 ENSDART00000173438
ENSDART00000137798
ENSDART00000172976
ENSDART00000171450
ENSDART00000184288
si:ch211-239e6.4
chr11_-_34480822 7.75 ENSDART00000129029
xyloside xylosyltransferase 1
chr13_-_18691041 7.74 ENSDART00000057867
sideroflexin 3
chr2_+_2772447 7.70 ENSDART00000124882
THO complex 1
chr15_+_17343319 7.67 ENSDART00000018461
vacuole membrane protein 1
chr5_-_13206878 7.65 ENSDART00000051666
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr22_-_10752471 7.32 ENSDART00000081191
SAS-6 centriolar assembly protein
chr6_+_46406565 7.13 ENSDART00000168440
ENSDART00000131203
ENSDART00000138567
ENSDART00000132845
polybromo 1, like
chr17_-_868004 7.11 ENSDART00000112803
WD repeat domain 20a
chr11_+_18183220 7.03 ENSDART00000113468

chr25_+_33202294 7.02 ENSDART00000131098
zgc:171719
chr2_-_32512648 6.95 ENSDART00000170674
ATP-binding cassette, sub-family F (GCN20), member 2a
chr7_+_32693890 6.94 ENSDART00000121972
solute carrier family 39 (zinc transporter), member 13
chr13_-_33654931 6.90 ENSDART00000020350
sorting nexin 5
chr20_-_46866934 6.73 ENSDART00000158178
si:ch73-21k16.4
chr5_-_4297459 6.72 ENSDART00000018895
serrate RNA effector molecule homolog (Arabidopsis)
chr24_+_15020402 6.62 ENSDART00000148102
docking protein 6
chr14_-_45558490 6.60 ENSDART00000165060
integrator complex subunit 5
chr16_+_20294976 6.56 ENSDART00000059619
FK506 binding protein 14
chr25_-_21782435 6.55 ENSDART00000089616
base methyltransferase of 25S rRNA 2 homolog
chr9_-_49964810 6.52 ENSDART00000167098
sodium channel, voltage-gated, type I, alpha
chr10_-_3427589 6.51 ENSDART00000133452
ENSDART00000037183
transmembrane p24 trafficking protein 2
chr5_-_26795438 6.50 ENSDART00000146124
si:ch211-102c2.7
chr2_-_48298985 6.50 ENSDART00000057957
integral membrane protein 2Cb
chr1_-_6085750 6.45 ENSDART00000138891
si:ch1073-345a8.1
chr5_-_3927692 6.45 ENSDART00000146840
ENSDART00000058346
complement component 1, q subcomponent binding protein
chr15_+_34933552 6.43 ENSDART00000155368
zgc:66024
chr2_+_5406236 6.40 ENSDART00000154167
SFT2 domain containing 3
chr3_-_34528306 6.37 ENSDART00000023039
septin 9a
chr19_-_1871415 6.32 ENSDART00000004585
CLPTM1-like
chr16_+_25259313 6.27 ENSDART00000058938
F-box protein 32
chr9_+_14023386 6.19 ENSDART00000140199
ENSDART00000124267
si:ch211-67e16.4
chr4_-_858434 6.12 ENSDART00000006961
sine oculis binding protein homolog (Drosophila) b
chr5_+_25733774 6.12 ENSDART00000137088
ENSDART00000098467
abhydrolase domain containing 17B
chr8_+_47683539 6.08 ENSDART00000190701
dipeptidyl-peptidase 9
chr1_-_23294753 6.06 ENSDART00000013263
UDP-glucose 6-dehydrogenase
chr12_-_44759246 6.05 ENSDART00000162888
dedicator of cytokinesis 1
chr21_-_36453594 6.04 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8
chr12_-_22355430 6.04 ENSDART00000153296
ENSDART00000056919
ENSDART00000159036
N-ethylmaleimide-sensitive factor b
chr5_-_52010122 6.00 ENSDART00000073627
ENSDART00000163898
ENSDART00000051003
cyclin-dependent kinase 7
chr8_-_1266181 5.97 ENSDART00000148654
ENSDART00000149924
cell division cycle 14B
chr22_-_11829436 5.92 ENSDART00000126784
protein tyrosine phosphatase, non-receptor type 4b
chr13_-_29980215 5.92 ENSDART00000042049
hypoxia inducible factor 1, alpha subunit inhibitor
chr9_-_22918413 5.87 ENSDART00000007392
ADP-ribosylation factor-like 5A
chr7_+_13684012 5.86 ENSDART00000056893
programmed cell death 7
chr7_+_53254234 5.84 ENSDART00000169830
thyroid hormone receptor interactor 4
chr13_-_24396003 5.84 ENSDART00000016211
TATA box binding protein
chr8_-_25034411 5.83 ENSDART00000135973
nuclear transcription factor Y, alpha, like
chr18_+_44849809 5.73 ENSDART00000097328
ADP-ribosylation factor GTPase activating protein 2
chr14_+_22457230 5.66 ENSDART00000019296
growth differentiation factor 9
chr16_-_54498109 5.66 ENSDART00000083713
CDC-like kinase 2b
chr13_-_24396199 5.64 ENSDART00000181093
TATA box binding protein
chr6_-_6248893 5.58 ENSDART00000124662
reticulon 4a
chr5_-_48070779 5.55 ENSDART00000078401
transmembrane protein 161B
chr7_-_32629458 5.54 ENSDART00000001376
ADP-ribosylation factor-like 14 effector protein
chr9_-_30243393 5.54 ENSDART00000089539
si:dkey-100n23.3
chr11_+_25693395 5.51 ENSDART00000110224
MON1 secretory trafficking family member Bb
chr14_-_899170 5.50 ENSDART00000165211
ENSDART00000031992
regulator of G protein signaling 14a
chr22_+_30047245 5.50 ENSDART00000142857
ENSDART00000141247
ENSDART00000140015
ENSDART00000040538
adducin 3 (gamma) a
chr6_+_52212574 5.46 ENSDART00000025940
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr14_-_26465729 5.44 ENSDART00000143454
synovial apoptosis inhibitor 1, synoviolin
chr25_+_35889102 5.43 ENSDART00000023453
ENSDART00000125821
ENSDART00000135441
LSM14A mRNA processing body assembly factor a
chr21_+_17016337 5.43 ENSDART00000065755
GPN-loop GTPase 3
chr2_-_21847935 5.41 ENSDART00000003940
RAB2A, member RAS oncogene family
chr7_+_74141297 5.41 ENSDART00000164992
RNA binding protein with multiple splicing
chr23_+_44611864 5.39 ENSDART00000145905
ENSDART00000132361
enolase 3, (beta, muscle)
chr2_+_34112100 5.37 ENSDART00000056666
ENSDART00000146624
kelch-like family member 20
chr22_-_5171829 5.36 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr17_+_17804752 5.33 ENSDART00000123350
serine palmitoyltransferase, long chain base subunit 2a
chr5_+_51833305 5.31 ENSDART00000165276
ENSDART00000166443
PAP associated domain containing 4
chr20_-_14462995 5.30 ENSDART00000152418
ENSDART00000044125
gene rich cluster, C10 gene
chr19_+_366034 5.20 ENSDART00000093383
vacuolar protein sorting 72 homolog (S. cerevisiae)
chr2_+_30249977 5.18 ENSDART00000109160
ENSDART00000135171
transmembrane protein 70
chr4_-_287425 5.17 ENSDART00000159128
enoyl CoA hydratase domain containing 3
chr3_-_30186296 5.16 ENSDART00000134395
ENSDART00000077057
ENSDART00000017422
TBC1 domain family, member 17
chr11_-_36230146 5.16 ENSDART00000135888
ENSDART00000189782
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr14_-_33278084 5.13 ENSDART00000132850
START domain containing 14
chr15_-_30984557 5.13 ENSDART00000080328
neurofibromin 1a
chr13_-_12667220 5.11 ENSDART00000079594
family with sequence similarity 241 member A
chr1_+_51615672 5.10 ENSDART00000165117
zgc:165656
chr20_-_48898371 5.08 ENSDART00000170617
5'-3' exoribonuclease 2
chr12_-_26491464 5.08 ENSDART00000153361
si:dkey-287g12.6
chr10_+_29771256 5.07 ENSDART00000193195
hypoxia up-regulated 1
chr3_-_34816893 5.07 ENSDART00000084448
ENSDART00000154696
proteasome 26S subunit, non-ATPase 11a
chr14_+_32918484 5.06 ENSDART00000105721
ligand of numb-protein X 2b
chr5_-_23596339 5.06 ENSDART00000024815
family with sequence similarity 76, member B
chr18_+_26429428 5.05 ENSDART00000142686
Bloom syndrome, RecQ helicase-like
chr14_-_33277743 5.04 ENSDART00000048130
START domain containing 14
chr18_-_35407530 5.03 ENSDART00000137663
small nuclear ribonucleoprotein polypeptide A
chr15_-_2519640 5.02 ENSDART00000047013
signal recognition particle receptor, B subunit
chr21_+_26028947 5.01 ENSDART00000028007
SPT6 homolog, histone chaperone
chr2_-_57918314 5.00 ENSDART00000138265
si:dkeyp-68b7.7
chr4_-_19693978 4.99 ENSDART00000100974
ENSDART00000040405
staphylococcal nuclease and tudor domain containing 1
chr1_+_38818268 4.97 ENSDART00000166864
signal peptidase complex subunit 3
chr18_-_35407695 4.95 ENSDART00000191845
ENSDART00000141703
small nuclear ribonucleoprotein polypeptide A
chr13_+_49727333 4.92 ENSDART00000168799
ENSDART00000037559
geranylgeranyl diphosphate synthase 1
chr19_+_6904314 4.89 ENSDART00000151502
si:ch1073-127d16.1
chr16_-_2390931 4.89 ENSDART00000149463
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr11_+_25560072 4.89 ENSDART00000124131
ENSDART00000147179
methyl-CpG binding domain protein 1b
chr12_+_10443785 4.88 ENSDART00000029133
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr5_-_51998708 4.88 ENSDART00000097194
serine incorporator 5
chr10_+_17747880 4.86 ENSDART00000135044
phosphatidylinositol glycan anchor biosynthesis, class O
chr20_-_48898560 4.85 ENSDART00000163071
5'-3' exoribonuclease 2
chr9_-_10805231 4.78 ENSDART00000193913
ENSDART00000078348
si:ch1073-416j23.1
chr11_-_16975190 4.77 ENSDART00000122222
succinate-CoA ligase, GDP-forming, beta subunit
chr18_-_35407289 4.76 ENSDART00000012018
small nuclear ribonucleoprotein polypeptide A
chr8_+_36500061 4.74 ENSDART00000185840
solute carrier family 7, member 4
chr20_-_45772306 4.74 ENSDART00000062092
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr15_-_14642186 4.71 ENSDART00000164166
si:dkey-260j18.2
chr10_-_7671219 4.71 ENSDART00000159330
prenylcysteine oxidase 1
chr8_+_387622 4.69 ENSDART00000167361
PYM homolog 1, exon junction complex associated factor
chr4_+_13931578 4.68 ENSDART00000142466
periphilin 1
chr18_+_5454341 4.67 ENSDART00000192649
DTW domain containing 1
chr5_+_32490238 4.65 ENSDART00000191839
NADPH dependent diflavin oxidoreductase 1
chr6_-_10725847 4.64 ENSDART00000184567
Sp3b transcription factor
chr16_+_25171832 4.62 ENSDART00000156416
wu:fe05a04
chr24_-_25004553 4.62 ENSDART00000080997
ENSDART00000136860
zinc finger, DHHC-type containing 20b
chr14_-_25935167 4.61 ENSDART00000139855
GTPase activating protein (SH3 domain) binding protein 1
chr4_-_5371639 4.59 ENSDART00000150697
si:dkey-14d8.1
chr25_+_17847054 4.59 ENSDART00000067290
zgc:162634
chr24_+_37533728 4.55 ENSDART00000061203
ras homolog family member T2
chr25_-_12412704 4.55 ENSDART00000168275
DET1, COP1 ubiquitin ligase partner
chr20_+_14968031 4.53 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vesicle-associated membrane protein 4
chr16_-_17345377 4.52 ENSDART00000143056
zyxin
chr23_+_4260458 4.48 ENSDART00000103747
serine/arginine-rich splicing factor 6a
chr4_+_20051478 4.47 ENSDART00000143642
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr10_-_42519773 4.45 ENSDART00000039187
membrane-associated ring finger (C3HC4) 5, like
chr19_-_34742440 4.44 ENSDART00000122625
ENSDART00000175621
elongator acetyltransferase complex subunit 2
chr1_-_47122058 4.43 ENSDART00000159925
ENSDART00000101143
ENSDART00000176803
major histocompatibility complex class I ZEA
chr12_+_47794089 4.41 ENSDART00000160726
polymerase (RNA) III (DNA directed) polypeptide A
chr14_+_164556 4.41 ENSDART00000185606
WD repeat domain 1
chr16_+_32184485 4.41 ENSDART00000084009
zinc finger with UFM1-specific peptidase domain
chr18_+_7553950 4.41 ENSDART00000193420
ENSDART00000062143
zgc:77650
chr5_-_56964547 4.39 ENSDART00000074400
TIA1 cytotoxic granule-associated RNA binding protein
chr1_-_8553165 4.38 ENSDART00000135197
ENSDART00000054981
zgc:112980
chr9_-_29003245 4.37 ENSDART00000183391
ENSDART00000188836
protein tyrosine phosphatase, non-receptor type 4a
chr14_-_31618243 4.36 ENSDART00000016592
membrane magnesium transporter 1
chr15_-_30984804 4.35 ENSDART00000157005
neurofibromin 1a
chr3_+_56574623 4.35 ENSDART00000130877
Rac family small GTPase 1b
chr21_-_36453417 4.34 ENSDART00000018350
CCR4-NOT transcription complex, subunit 8
chr19_-_11015238 4.34 ENSDART00000010997
tropomyosin 3
chr5_+_23045096 4.33 ENSDART00000171719
alpha thalassemia/mental retardation syndrome X-linked, like
chr12_-_20409794 4.32 ENSDART00000077936
leucine carboxyl methyltransferase 1
chr20_+_54312970 4.31 ENSDART00000024598
ENSDART00000193172
zona pellucida glycoprotein 2, tandem duplicate 5
chr20_+_23947004 4.31 ENSDART00000144195
caspase 8 associated protein 2
chr13_+_41917606 4.30 ENSDART00000114741
polymerase (RNA) I polypeptide B
chr23_-_13840433 4.30 ENSDART00000104831
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr20_+_54299419 4.30 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
chr21_+_38033226 4.30 ENSDART00000085728
Kruppel-like factor 8
chr15_-_11683529 4.29 ENSDART00000161445
fukutin related protein
chr5_-_32489796 4.28 ENSDART00000168870
G protein-coupled receptor 107
chr10_+_36439293 4.27 ENSDART00000043802
ubiquitin specific peptidase like 1
chr5_-_30516646 4.27 ENSDART00000014666
archain 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of etv5a+etv5b_elk1_elk4_etv1_elf1_erf+erfl3_gabpa_elk3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0070914 UV-damage excision repair(GO:0070914)
2.6 7.7 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
2.4 7.2 GO:0042245 RNA repair(GO:0042245)
2.2 6.7 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
2.1 12.8 GO:0070734 histone H3-K27 methylation(GO:0070734)
2.1 8.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
1.9 9.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
1.9 7.6 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
1.9 13.3 GO:0014009 glial cell proliferation(GO:0014009)
1.9 13.2 GO:0040016 embryonic cleavage(GO:0040016)
1.9 5.7 GO:0030237 female sex determination(GO:0030237)
1.9 5.6 GO:0000390 spliceosomal complex disassembly(GO:0000390)
1.7 5.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
1.6 6.5 GO:0048211 Golgi vesicle docking(GO:0048211)
1.6 4.9 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
1.6 7.9 GO:0097355 protein localization to heterochromatin(GO:0097355)
1.5 13.8 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
1.5 5.9 GO:1903292 protein localization to Golgi membrane(GO:1903292)
1.4 5.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
1.4 4.3 GO:0034421 post-translational protein acetylation(GO:0034421)
1.4 7.1 GO:0031053 primary miRNA processing(GO:0031053)
1.4 5.7 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.4 4.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
1.3 21.2 GO:0019985 translesion synthesis(GO:0019985)
1.3 4.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.3 3.9 GO:0048478 replication fork protection(GO:0048478)
1.3 5.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
1.3 5.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
1.3 22.6 GO:0046688 response to copper ion(GO:0046688)
1.2 9.9 GO:0019405 alditol catabolic process(GO:0019405)
1.2 5.9 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
1.1 4.5 GO:0090161 Golgi ribbon formation(GO:0090161)
1.1 5.6 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
1.1 7.8 GO:0045901 positive regulation of translational elongation(GO:0045901)
1.1 3.3 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
1.1 16.1 GO:0000076 DNA replication checkpoint(GO:0000076)
1.1 4.3 GO:0051645 Golgi localization(GO:0051645)
1.1 13.8 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
1.1 8.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.0 3.1 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
1.0 9.2 GO:0006465 signal peptide processing(GO:0006465)
1.0 3.0 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
1.0 2.9 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
1.0 2.9 GO:0010847 regulation of chromatin assembly(GO:0010847)
1.0 2.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
1.0 5.7 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.9 4.7 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.9 4.7 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.9 15.9 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.9 2.8 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.9 18.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.9 3.4 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.9 3.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.9 4.3 GO:1904867 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.8 12.7 GO:0061055 myotome development(GO:0061055)
0.8 9.2 GO:0006999 nuclear pore organization(GO:0006999)
0.8 3.3 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.8 3.3 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.8 2.5 GO:0042730 fibrinolysis(GO:0042730)
0.8 5.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.8 2.4 GO:0042832 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.8 3.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.8 8.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.8 1.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.8 5.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.8 3.0 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.7 2.2 GO:0061355 Wnt protein secretion(GO:0061355)
0.7 2.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
0.7 9.7 GO:0042572 retinol metabolic process(GO:0042572)
0.7 3.0 GO:1903232 melanosome assembly(GO:1903232)
0.7 4.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7 1.4 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.7 6.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.7 6.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.7 2.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.7 5.4 GO:0034063 stress granule assembly(GO:0034063)
0.7 5.4 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.7 2.0 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.7 13.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.6 3.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.6 1.9 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.6 4.5 GO:0006301 postreplication repair(GO:0006301)
0.6 2.5 GO:0042985 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.6 4.4 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.6 8.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.6 4.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.6 2.4 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.6 1.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.6 10.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.6 2.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.6 2.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.6 1.1 GO:0010658 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.6 6.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.6 8.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.5 5.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.5 2.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.5 3.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.5 1.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.5 4.3 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.5 1.6 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.5 4.2 GO:0048730 epidermis morphogenesis(GO:0048730)
0.5 2.1 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.5 4.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.5 3.0 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.5 2.0 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.5 1.5 GO:0010586 miRNA metabolic process(GO:0010586)
0.5 5.4 GO:0006611 protein export from nucleus(GO:0006611)
0.5 1.4 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.5 1.9 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.5 1.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.5 2.3 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.5 5.5 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.5 3.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.4 2.2 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.4 0.9 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.4 4.4 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.4 4.0 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.4 5.3 GO:0009791 post-embryonic development(GO:0009791)
0.4 6.2 GO:0016926 protein desumoylation(GO:0016926)
0.4 1.7 GO:0019348 dolichol metabolic process(GO:0019348)
0.4 2.1 GO:0048855 adenohypophysis morphogenesis(GO:0048855)
0.4 4.7 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.4 6.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.4 0.4 GO:0045191 regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.4 5.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 7.7 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.4 0.8 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.4 6.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.4 13.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.4 4.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.4 8.6 GO:0007520 myoblast fusion(GO:0007520)
0.4 3.1 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.4 1.9 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.4 11.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.4 1.9 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.4 1.1 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.4 1.9 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.4 12.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.4 2.2 GO:0032447 protein urmylation(GO:0032447)
0.4 2.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 2.6 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.4 2.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.4 1.1 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.4 1.1 GO:0008344 adult locomotory behavior(GO:0008344)
0.4 3.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.4 7.1 GO:0016233 telomere capping(GO:0016233)
0.4 7.1 GO:0008354 germ cell migration(GO:0008354)
0.4 2.1 GO:0044209 AMP salvage(GO:0044209)
0.4 4.9 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.3 28.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.3 2.4 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.3 1.0 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.3 2.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.3 24.7 GO:0006400 tRNA modification(GO:0006400)
0.3 1.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.3 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 2.3 GO:0021982 pineal gland development(GO:0021982)
0.3 2.9 GO:0007220 Notch receptor processing(GO:0007220)
0.3 7.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 2.3 GO:0010830 regulation of myotube differentiation(GO:0010830) regulation of skeletal muscle fiber development(GO:0048742)
0.3 7.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.3 0.9 GO:0071025 RNA surveillance(GO:0071025)
0.3 0.9 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 4.1 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.3 8.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.3 2.8 GO:0090398 cellular senescence(GO:0090398)
0.3 5.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.3 3.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.3 5.2 GO:0046660 female sex differentiation(GO:0046660)
0.3 3.0 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.3 6.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.3 4.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.3 2.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 0.9 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.3 0.6 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.3 4.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 0.8 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.3 5.6 GO:0071456 cellular response to hypoxia(GO:0071456)
0.3 6.0 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.3 0.8 GO:0006167 AMP biosynthetic process(GO:0006167)
0.3 9.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.3 1.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 12.6 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.3 3.5 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.3 4.0 GO:0045116 protein neddylation(GO:0045116)
0.3 0.8 GO:0051026 chiasma assembly(GO:0051026)
0.3 3.4 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271) DNA strand elongation(GO:0022616)
0.3 5.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.3 4.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.3 7.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.3 0.3 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.3 3.3 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.3 1.8 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.3 2.5 GO:0039023 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.3 1.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 5.0 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.2 2.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 8.6 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.2 17.7 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.2 0.7 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.2 0.7 GO:0097435 fibril organization(GO:0097435)
0.2 1.6 GO:0036010 protein localization to endosome(GO:0036010)
0.2 1.4 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.2 1.4 GO:0021634 optic nerve formation(GO:0021634)
0.2 4.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 6.6 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.2 0.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 3.4 GO:0050685 positive regulation of mRNA processing(GO:0050685)
0.2 1.1 GO:1901207 regulation of heart looping(GO:1901207)
0.2 0.6 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.2 0.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 4.0 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 8.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 1.5 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 2.3 GO:0043489 RNA stabilization(GO:0043489)
0.2 4.0 GO:0035675 neuromast hair cell development(GO:0035675)
0.2 2.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.2 1.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 1.8 GO:0006623 protein targeting to vacuole(GO:0006623)
0.2 0.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 1.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 1.6 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.2 1.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) histone mRNA metabolic process(GO:0008334)
0.2 0.5 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 0.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 1.0 GO:0072319 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.2 0.9 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 11.5 GO:0007030 Golgi organization(GO:0007030)
0.2 2.9 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 1.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 5.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 3.8 GO:0090148 membrane fission(GO:0090148)
0.2 4.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.2 0.5 GO:0005997 xylulose metabolic process(GO:0005997)
0.2 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 6.1 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.2 0.5 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 0.9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 0.5 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.2 0.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 1.9 GO:0033198 response to ATP(GO:0033198)
0.2 1.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 1.0 GO:0014846 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575) esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.7 GO:0014074 response to purine-containing compound(GO:0014074) response to organophosphorus(GO:0046683)
0.1 0.4 GO:0016180 snRNA metabolic process(GO:0016073) snRNA processing(GO:0016180)
0.1 0.7 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 5.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.7 GO:0032475 otolith formation(GO:0032475)
0.1 2.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.4 GO:0060969 negative regulation of chromatin silencing(GO:0031936) negative regulation of gene silencing(GO:0060969)
0.1 1.9 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 0.4 GO:0050930 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.1 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 1.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 2.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.5 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 1.8 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 0.5 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 2.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 3.1 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.1 1.3 GO:0042026 protein refolding(GO:0042026)
0.1 0.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 4.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.1 1.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 3.4 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 1.4 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.8 GO:0000959 mitochondrial RNA metabolic process(GO:0000959)
0.1 6.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.4 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.9 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 2.4 GO:0003094 glomerular filtration(GO:0003094)
0.1 7.5 GO:0018210 peptidyl-threonine modification(GO:0018210)
0.1 0.1 GO:0035303 regulation of dephosphorylation(GO:0035303)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.1 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.6 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.1 0.3 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.1 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.8 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.1 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 1.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 2.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 14.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 0.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.6 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.6 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 1.2 GO:0015693 magnesium ion transport(GO:0015693)
0.1 2.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 0.9 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.6 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.1 6.3 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.1 0.5 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 3.2 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.1 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.3 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 1.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.6 GO:0051014 actin filament severing(GO:0051014)
0.1 4.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 1.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 4.1 GO:0030098 lymphocyte differentiation(GO:0030098)
0.1 0.8 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 1.0 GO:0070828 heterochromatin organization(GO:0070828)
0.1 3.6 GO:0031047 gene silencing by RNA(GO:0031047)
0.1 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 2.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.1 6.3 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 7.5 GO:1903706 regulation of hemopoiesis(GO:1903706)
0.1 3.7 GO:0030901 midbrain development(GO:0030901)
0.1 4.7 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.1 0.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.9 GO:0031060 regulation of histone methylation(GO:0031060)
0.1 1.8 GO:0006497 protein lipidation(GO:0006497)
0.1 1.1 GO:0006825 copper ion transport(GO:0006825)
0.1 2.1 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 0.2 GO:0045687 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 3.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 4.5 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 0.3 GO:0032366 intracellular sterol transport(GO:0032366)
0.1 2.4 GO:0021591 ventricular system development(GO:0021591)
0.1 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.1 GO:0072350 citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350)
0.1 0.2 GO:0036315 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.7 GO:0061351 neural precursor cell proliferation(GO:0061351)
0.1 1.8 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 5.7 GO:0016485 protein processing(GO:0016485)
0.1 1.6 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 2.9 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 3.2 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 2.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.3 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.3 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.2 GO:0030242 pexophagy(GO:0030242)
0.1 2.0 GO:0030261 chromosome condensation(GO:0030261)
0.1 1.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.8 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 3.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0051030 snRNA transport(GO:0051030)
0.0 1.0 GO:0050821 protein stabilization(GO:0050821)
0.0 1.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 1.8 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 3.3 GO:0031101 fin regeneration(GO:0031101)
0.0 1.2 GO:0045761 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.6 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.7 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 7.4 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.2 GO:0072422 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 1.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.8 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.4 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.8 GO:0019835 cytolysis(GO:0019835)
0.0 1.3 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 1.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.2 GO:0098781 ncRNA transcription(GO:0098781)
0.0 0.6 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.6 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.0 1.3 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.7 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.7 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.2 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.3 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 0.5 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.2 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 1.2 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.7 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.5 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.6 GO:0009306 protein secretion(GO:0009306)
0.0 0.1 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.4 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.6 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 2.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.2 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 2.1 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.3 GO:0006284 base-excision repair(GO:0006284)
0.0 0.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.3 GO:0022406 membrane docking(GO:0022406) vesicle docking(GO:0048278)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.8 14.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
2.6 10.6 GO:0043291 RAVE complex(GO:0043291)
2.4 7.3 GO:0098536 deuterosome(GO:0098536)
2.3 9.2 GO:0005787 signal peptidase complex(GO:0005787)
2.1 12.6 GO:0000938 GARP complex(GO:0000938)
1.7 5.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.6 9.9 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
1.6 4.8 GO:0042709 succinate-CoA ligase complex(GO:0042709)
1.5 13.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
1.3 5.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
1.1 7.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.1 5.4 GO:0031415 NatA complex(GO:0031415)
1.0 3.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.0 5.0 GO:0031501 mannosyltransferase complex(GO:0031501)
0.9 4.7 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.9 6.5 GO:1990130 Iml1 complex(GO:1990130)
0.8 8.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.8 5.0 GO:0000243 commitment complex(GO:0000243)
0.8 5.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.8 18.9 GO:0005685 U1 snRNP(GO:0005685)
0.8 4.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.8 4.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.8 10.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.8 8.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.7 3.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.7 18.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.7 13.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.7 5.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.7 4.0 GO:0071986 Ragulator complex(GO:0071986)
0.7 3.3 GO:0031298 replication fork protection complex(GO:0031298)
0.6 5.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.6 6.0 GO:0005675 holo TFIIH complex(GO:0005675)
0.6 12.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.6 11.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.6 2.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.6 2.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 3.9 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.5 2.9 GO:0070695 FHF complex(GO:0070695)
0.5 4.9 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.5 1.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.5 4.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.5 3.2 GO:0070847 core mediator complex(GO:0070847)
0.4 1.3 GO:0097361 CIA complex(GO:0097361)
0.4 3.5 GO:0016586 RSC complex(GO:0016586)
0.4 3.7 GO:0000974 Prp19 complex(GO:0000974)
0.4 3.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.4 6.1 GO:0070187 telosome(GO:0070187)
0.4 3.1 GO:0005682 U5 snRNP(GO:0005682)
0.4 3.0 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4 4.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.4 1.5 GO:0032838 cell projection cytoplasm(GO:0032838)
0.4 2.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.4 4.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.4 2.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.3 5.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 5.9 GO:0000813 ESCRT I complex(GO:0000813)
0.3 0.3 GO:0071203 WASH complex(GO:0071203)
0.3 1.4 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.3 7.0 GO:0032039 integrator complex(GO:0032039)
0.3 3.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 9.8 GO:0005795 Golgi stack(GO:0005795)
0.3 1.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.3 5.2 GO:0015030 Cajal body(GO:0015030)
0.3 2.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.3 1.5 GO:0070390 transcription export complex 2(GO:0070390)
0.3 2.4 GO:0030686 90S preribosome(GO:0030686)
0.3 4.9 GO:0071011 precatalytic spliceosome(GO:0071011)
0.3 1.6 GO:0070876 SOSS complex(GO:0070876)
0.3 2.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 3.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.3 1.3 GO:0018444 translation release factor complex(GO:0018444)
0.2 5.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.2 9.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.2 2.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 2.2 GO:0071797 LUBAC complex(GO:0071797)
0.2 0.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 4.6 GO:0043596 nuclear replication fork(GO:0043596)
0.2 0.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 1.8 GO:0031931 TORC1 complex(GO:0031931)
0.2 1.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 1.5 GO:0035101 FACT complex(GO:0035101)
0.2 1.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.2 1.3 GO:0017119 Golgi transport complex(GO:0017119)
0.2 5.3 GO:0035861 site of double-strand break(GO:0035861)
0.2 8.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 7.6 GO:0016605 PML body(GO:0016605)
0.2 0.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 28.1 GO:0005769 early endosome(GO:0005769)
0.2 3.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 8.4 GO:0005811 lipid particle(GO:0005811)
0.2 1.6 GO:0016272 prefoldin complex(GO:0016272)
0.2 4.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 81.5 GO:0000139 Golgi membrane(GO:0000139)
0.2 13.9 GO:0005802 trans-Golgi network(GO:0005802)
0.2 4.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 6.3 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 4.0 GO:0035102 PRC1 complex(GO:0035102)
0.2 0.2 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.2 4.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 0.6 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.2 9.5 GO:0072686 mitotic spindle(GO:0072686)
0.1 4.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.5 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 12.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 2.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 2.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 6.1 GO:0016592 mediator complex(GO:0016592)
0.1 6.8 GO:0055029 nuclear DNA-directed RNA polymerase complex(GO:0055029)
0.1 0.4 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 9.2 GO:0098573 intrinsic component of mitochondrial membrane(GO:0098573)
0.1 19.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 0.7 GO:0016589 NURF complex(GO:0016589)
0.1 0.9 GO:0001772 immunological synapse(GO:0001772)
0.1 2.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 8.1 GO:0001726 ruffle(GO:0001726)
0.1 3.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 23.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 5.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.9 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.1 4.2 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 0.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 1.8 GO:0005876 spindle microtubule(GO:0005876)
0.1 2.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 4.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.3 GO:0042382 paraspeckles(GO:0042382)
0.1 8.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 6.1 GO:0031201 SNARE complex(GO:0031201)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 3.8 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 3.9 GO:0005643 nuclear pore(GO:0005643)
0.1 6.2 GO:0030027 lamellipodium(GO:0030027)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.1 2.7 GO:0031012 extracellular matrix(GO:0031012)
0.1 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 10.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 0.4 GO:0030662 coated vesicle membrane(GO:0030662)
0.1 13.2 GO:0030425 dendrite(GO:0030425)
0.1 0.6 GO:0032021 NELF complex(GO:0032021)
0.1 0.6 GO:0000124 SAGA complex(GO:0000124)
0.1 0.3 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 6.3 GO:0014069 postsynaptic density(GO:0014069)
0.1 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.5 GO:0045252 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.1 14.5 GO:0005768 endosome(GO:0005768)
0.1 2.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 3.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 5.2 GO:0016604 nuclear body(GO:0016604)
0.1 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 3.4 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 29.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 9.9 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 1.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531) BRISC complex(GO:0070552)
0.0 0.1 GO:0030880 RNA polymerase complex(GO:0030880)
0.0 1.4 GO:0008305 integrin complex(GO:0008305)
0.0 2.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 5.4 GO:0099568 cell cortex(GO:0005938) cytoplasmic region(GO:0099568)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 38.8 GO:0005576 extracellular region(GO:0005576)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0005903 brush border(GO:0005903)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.3 GO:0009986 cell surface(GO:0009986)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.0 GO:0072380 TRC complex(GO:0072380)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 20.1 GO:0016531 copper chaperone activity(GO:0016531)
2.8 8.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
2.7 21.8 GO:0030619 U1 snRNA binding(GO:0030619)
2.6 10.2 GO:0070182 DNA polymerase binding(GO:0070182)
2.5 9.9 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
2.4 9.6 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
2.3 6.8 GO:0071532 ankyrin repeat binding(GO:0071532)
1.9 7.6 GO:0034511 U3 snoRNA binding(GO:0034511)
1.8 10.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
1.6 24.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
1.6 11.5 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
1.6 4.8 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
1.5 6.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
1.5 4.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.3 3.9 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.3 5.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.3 7.7 GO:0022889 serine transmembrane transporter activity(GO:0022889)
1.2 22.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
1.2 4.7 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
1.1 9.0 GO:0034452 dynactin binding(GO:0034452)
1.1 7.8 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
1.1 7.5 GO:0070698 type I activin receptor binding(GO:0070698)
1.0 3.1 GO:0019777 Atg12 transferase activity(GO:0019777)
1.0 3.0 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
1.0 5.0 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
1.0 4.9 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
1.0 2.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.9 4.7 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.9 4.7 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.9 11.2 GO:0043495 protein anchor(GO:0043495)
0.9 2.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.9 2.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.9 8.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.9 8.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.9 4.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.9 9.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.9 6.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.9 4.3 GO:0032183 SUMO binding(GO:0032183)
0.8 4.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.8 3.3 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.8 3.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.8 6.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.8 6.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.8 7.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.7 2.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.7 14.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.7 6.4 GO:0008494 translation activator activity(GO:0008494)
0.7 2.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.7 4.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.7 2.1 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.7 2.0 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.7 5.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.7 2.0 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.7 15.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.6 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.6 4.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.6 4.6 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.6 7.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.6 2.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.5 2.6 GO:0008106 alditol:NADP+ 1-oxidoreductase activity(GO:0004032) alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.5 13.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 8.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.5 6.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.5 5.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.5 1.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.5 4.4 GO:0032977 membrane insertase activity(GO:0032977)
0.5 13.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.5 6.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.5 6.0 GO:0005537 mannose binding(GO:0005537)
0.5 1.8 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.4 2.2 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.4 4.0 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.4 16.9 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.4 1.3 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.4 2.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.4 1.6 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.4 3.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.4 1.9 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.4 5.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.4 1.5 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.4 9.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.4 1.8 GO:0060182 apelin receptor activity(GO:0060182)
0.3 1.9 GO:0008126 acetylesterase activity(GO:0008126)
0.3 2.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 0.9 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.3 4.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 0.9 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.3 0.9 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.3 7.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.3 2.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 4.6 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.3 1.4 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.3 2.2 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.3 1.9 GO:0035173 histone kinase activity(GO:0035173)
0.3 1.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3 2.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 2.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 5.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 0.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 1.9 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 5.0 GO:0031267 small GTPase binding(GO:0031267)
0.2 1.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 4.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 2.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 3.6 GO:0070122 isopeptidase activity(GO:0070122)
0.2 2.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 4.0 GO:0035497 cAMP response element binding(GO:0035497)
0.2 3.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2 3.2 GO:0051117 ATPase binding(GO:0051117)
0.2 3.5 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 3.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.2 3.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 1.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 0.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 20.5 GO:0004519 endonuclease activity(GO:0004519)
0.2 0.8 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 8.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 1.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 1.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.5 GO:0035198 miRNA binding(GO:0035198)
0.2 1.6 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 0.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 1.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 0.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 8.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.2 2.9 GO:0032190 acrosin binding(GO:0032190)
0.2 5.6 GO:0051018 protein kinase A binding(GO:0051018)
0.2 4.2 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.2 3.3 GO:0097602 cullin family protein binding(GO:0097602)
0.2 7.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.9 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.6 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.2 39.8 GO:0030246 carbohydrate binding(GO:0030246)
0.1 2.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 2.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 1.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 6.5 GO:0030276 clathrin binding(GO:0030276)
0.1 5.4 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.8 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 19.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 6.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 22.2 GO:0060090 binding, bridging(GO:0060090)
0.1 23.0 GO:0000149 SNARE binding(GO:0000149)
0.1 1.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 1.5 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.1 0.9 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 0.6 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 1.3 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 1.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.5 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 3.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.8 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 1.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 2.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 18.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.3 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 22.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 43.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 2.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 6.7 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 0.7 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 1.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.7 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 2.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.4 GO:0031386 protein tag(GO:0031386)
0.1 1.9 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 3.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.2 GO:0015923 mannosidase activity(GO:0015923)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 7.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 5.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 13.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 2.7 GO:0019003 GDP binding(GO:0019003)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 1.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.9 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 3.4 GO:0005507 copper ion binding(GO:0005507)
0.1 22.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1 7.0 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.1 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 12.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 2.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 12.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 28.8 GO:0005525 GTP binding(GO:0005525)
0.1 1.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 1.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.4 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 1.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.0 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 1.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0015925 galactosidase activity(GO:0015925)
0.0 1.8 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.7 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0016722 oxidoreductase activity, oxidizing metal ions(GO:0016722)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 9.4 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.2 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 3.0 GO:0043492 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 2.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.3 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.4 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0031826 G-protein coupled serotonin receptor binding(GO:0031821) type 2A serotonin receptor binding(GO:0031826)
0.0 0.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.7 7.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5 4.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5 7.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.5 24.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 8.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 2.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.3 0.6 SIG CHEMOTAXIS Genes related to chemotaxis
0.3 4.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 0.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 3.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 6.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 2.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 1.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 4.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 3.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 1.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 4.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 8.5 PID PLK1 PATHWAY PLK1 signaling events
0.2 3.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 6.1 PID AURORA B PATHWAY Aurora B signaling
0.2 1.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 5.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 5.1 PID FOXO PATHWAY FoxO family signaling
0.1 1.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 2.9 PID ATM PATHWAY ATM pathway
0.1 3.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 3.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.7 PID BARD1 PATHWAY BARD1 signaling events
0.1 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 6.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.2 PID ARF 3PATHWAY Arf1 pathway
0.1 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.3 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.9 PID E2F PATHWAY E2F transcription factor network
0.1 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 6.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID P73PATHWAY p73 transcription factor network
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 23.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
1.2 14.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.8 9.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.7 4.1 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.7 6.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.6 27.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.6 10.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.6 13.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.5 3.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.5 9.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.5 9.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.5 4.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.5 7.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.5 10.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.4 5.6 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.4 8.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.4 9.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.4 5.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.4 13.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.3 16.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 13.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.3 4.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 8.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 2.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 2.9 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.3 11.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 5.9 REACTOME KINESINS Genes involved in Kinesins
0.3 16.4 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.3 5.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 2.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.2 8.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 5.9 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.2 2.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 0.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 0.6 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.2 2.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 13.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 0.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 2.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 12.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 4.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.4 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1 1.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.8 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 2.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 5.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 4.4 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 1.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling