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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for esr1+esr2a+esr2b

Z-value: 0.38

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Transcription factors associated with esr1+esr2a+esr2b

Gene Symbol Gene ID Gene Info
ENSDARG00000004111 estrogen receptor 1
ENSDARG00000016454 estrogen receptor 2a
ENSDARG00000034181 estrogen receptor 2b
ENSDARG00000112357 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
esr2bdr11_v1_chr13_+_37022601_370226320.625.8e-03Click!
esr1dr11_v1_chr20_-_26382284_263822840.532.3e-02Click!
esr2adr11_v1_chr20_+_21583639_21583639-0.145.7e-01Click!

Activity profile of esr1+esr2a+esr2b motif

Sorted Z-values of esr1+esr2a+esr2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_44027391 1.03 ENSDART00000145404
crystallin, beta B1
chr12_+_49125510 0.95 ENSDART00000185804

chr5_-_71722257 0.85 ENSDART00000013404
adenylate kinase 1
chr5_+_62723233 0.77 ENSDART00000183718
nanos homolog 2
chr13_+_50375800 0.73 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr1_-_44704261 0.73 ENSDART00000133210
si:dkey-28b4.8
chr20_+_54738210 0.69 ENSDART00000151399
p21 protein (Cdc42/Rac)-activated kinase 7
chr1_-_30039331 0.69 ENSDART00000086935
ENSDART00000143800
zgc:153256
chr4_+_17280868 0.69 ENSDART00000145349
branched chain amino-acid transaminase 1, cytosolic
chr12_-_47782623 0.67 ENSDART00000115742
selenoprotein U1b
chr8_+_24745041 0.67 ENSDART00000148872
solute carrier family 16, member 4
chr12_+_7491690 0.63 ENSDART00000152564
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr4_-_191736 0.61 ENSDART00000169187
ENSDART00000192054
protein tyrosine phosphatase, receptor type, O
chr12_-_27242498 0.61 ENSDART00000152609
ENSDART00000152170
si:dkey-11c5.11
chr2_-_38000276 0.59 ENSDART00000034790
Purkinje cell protein 4 like 1
chr1_-_14694809 0.57 ENSDART00000193331

chr7_+_29012033 0.51 ENSDART00000173909
ENSDART00000145762
dynein, axonemal, assembly factor 1
chr6_-_40352215 0.50 ENSDART00000103992
tubulin tyrosine ligase-like family, member 3
chr7_+_39720317 0.49 ENSDART00000164996
si:dkey-58i8.5
chr3_+_28953274 0.49 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr5_+_42467867 0.48 ENSDART00000172028
Pim proto-oncogene, serine/threonine kinase, related 58
chr23_+_42810055 0.48 ENSDART00000186647
myosin, light chain 9a, regulatory
chr23_-_39636195 0.47 ENSDART00000144439
von Willebrand factor A domain containing 1
chr9_-_48736388 0.47 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr11_+_5842632 0.47 ENSDART00000111374
ENSDART00000158599
NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)
chr17_+_46739693 0.46 ENSDART00000097810
Pim proto-oncogene, serine/threonine kinase, related 22
chr1_-_59176949 0.45 ENSDART00000128742

chr8_+_23213320 0.45 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr4_+_38344 0.45 ENSDART00000170197
ENSDART00000175348
putative homeodomain transcription factor 2
chr5_+_70155935 0.45 ENSDART00000165570
regulator of G protein signaling 3a
chr8_+_21406769 0.45 ENSDART00000135766
si:dkey-163f12.6
chr22_-_2886937 0.44 ENSDART00000063533
aquaporin 12
chr13_-_36703164 0.44 ENSDART00000044357
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr15_-_28095532 0.44 ENSDART00000191490
crystallin, beta A1a
chr17_+_42027969 0.44 ENSDART00000147563
kizuna centrosomal protein
chr17_-_39786222 0.43 ENSDART00000154515
Pim proto-oncogene, serine/threonine kinase, related 62
chr1_+_57311901 0.42 ENSDART00000149397
mycbp associated protein
chr5_+_20693724 0.42 ENSDART00000141368
si:ch211-240b21.2
chr16_+_10963602 0.41 ENSDART00000141032
POU class 2 homeobox 2a
chr24_-_39610585 0.41 ENSDART00000066506
cytochrome c oxidase subunit VIb polypeptide 1
chr25_+_4954220 0.41 ENSDART00000156034
si:ch73-265h17.2
chr6_-_49873020 0.41 ENSDART00000148511
GNAS complex locus
chr5_+_2815021 0.40 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr20_+_1398564 0.40 ENSDART00000002242
liver-enriched gene 1, tandem duplicate 2
chr16_+_41517188 0.39 ENSDART00000049976
si:dkey-11p23.7
chr7_-_51032128 0.39 ENSDART00000182781
ENSDART00000121574
collagen, type IV, alpha 6
chr1_+_54626491 0.39 ENSDART00000136063
si:ch211-202h22.9
chr18_+_31016379 0.38 ENSDART00000172461
ENSDART00000163471
urate (5-hydroxyiso-) hydrolase a
chr4_-_5826320 0.38 ENSDART00000165354
forkhead box M1
chr14_-_215051 0.38 ENSDART00000054822
NK3 homeobox 2
chr23_-_45568816 0.38 ENSDART00000076086
cytochrome P450, family 17, subfamily A, polypeptide 2
chr6_+_12853655 0.37 ENSDART00000156341
family with sequence similarity 117, member Ba
chr20_-_43462190 0.37 ENSDART00000100697
Pim proto-oncogene, serine/threonine kinase, related 133
chr21_-_25756119 0.37 ENSDART00000002341
claudin c
chr1_-_17650223 0.37 ENSDART00000043484
si:dkey-256e7.5
chr4_+_18489207 0.35 ENSDART00000135276
si:dkey-202b22.5
chr23_-_45319592 0.35 ENSDART00000189861
coiled-coil domain containing 171
chr25_+_3326885 0.34 ENSDART00000104866
lactate dehydrogenase Bb
chr13_+_8677166 0.34 ENSDART00000181016
ENSDART00000135028
PROP paired-like homeobox 1
chr23_+_42813415 0.34 ENSDART00000055577
myosin, light chain 9a, regulatory
chr5_-_51148298 0.34 ENSDART00000042420
coiled-coil domain containing 180
chr18_+_7456888 0.34 ENSDART00000081468
telomere repeat binding bouquet formation protein 1
chr6_+_7250824 0.34 ENSDART00000177226
DAZ interacting zinc finger protein 1
chr11_-_11471857 0.34 ENSDART00000030103
keratin 94
chr9_-_710896 0.34 ENSDART00000180478
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr12_+_18533198 0.33 ENSDART00000189729
meiosis specific with OB domains
chr11_+_24815927 0.33 ENSDART00000146838
RAB interacting factor
chr11_-_24681292 0.33 ENSDART00000089601
olfactomedin-like 3b
chr13_+_21826369 0.33 ENSDART00000165150
ENSDART00000192115
zinc finger, SWIM-type containing 8
chr7_+_568819 0.32 ENSDART00000173716
neurexin 2b
chr3_+_1182315 0.32 ENSDART00000055430
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr8_+_54188978 0.32 ENSDART00000175913

chr16_+_23972126 0.32 ENSDART00000132742
ENSDART00000145330
apolipoprotein C-I
chr22_-_15593824 0.32 ENSDART00000123125
tropomyosin 4a
chr8_+_39760258 0.32 ENSDART00000037914
cytochrome c oxidase subunit VIa polypeptide 1
chr23_-_45705525 0.32 ENSDART00000148959
endothelin receptor type Ab
chr15_-_22251089 0.32 ENSDART00000153646
si:ch211-286b4.4
chr9_+_52613820 0.32 ENSDART00000168753
ENSDART00000165580
ENSDART00000164769
si:ch211-241j8.2
chr11_+_6010177 0.32 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
GTP binding protein 3, mitochondrial
chr6_+_475264 0.31 ENSDART00000193615

chr11_+_24816238 0.31 ENSDART00000115356
RAB interacting factor
chr8_-_49431939 0.30 ENSDART00000011453
ENSDART00000088240
ENSDART00000114173
synaptophysin b
chr18_-_44285539 0.30 ENSDART00000137222
Pim proto-oncogene, serine/threonine kinase, related 179
chr16_+_4838808 0.30 ENSDART00000179363
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr18_+_62932 0.30 ENSDART00000052638
solute carrier family 27 (fatty acid transporter), member 2a
chr23_-_31372639 0.30 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
high mobility group nucleosomal binding domain 3
chr3_-_61592417 0.29 ENSDART00000155082
neuronal pentraxin 2a
chr11_-_2478374 0.29 ENSDART00000173205
si:ch73-267c23.10
chr13_-_9525527 0.29 ENSDART00000190618

chr8_+_46536893 0.29 ENSDART00000124023
Pim proto-oncogene, serine/threonine kinase, related 187
chr25_-_16600811 0.29 ENSDART00000011397
carboxypeptidase A2 (pancreatic)
chr22_-_38274188 0.29 ENSDART00000139420
ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr23_+_44634187 0.29 ENSDART00000143688
si:ch73-265d7.2
chr20_+_18232893 0.29 ENSDART00000189225
potassium channel tetramerization domain containing 1
chr3_-_13147310 0.28 ENSDART00000160840
protein kinase, cAMP-dependent, regulatory, type I, beta
chr11_+_30162407 0.28 ENSDART00000190333
ENSDART00000127502
cyclin-dependent kinase-like 5
chr14_-_8724290 0.28 ENSDART00000161171
Pim proto-oncogene, serine/threonine kinase, related 56
chr5_-_1963498 0.28 ENSDART00000073462
ribosomal protein, large, P0
chr23_-_38054 0.28 ENSDART00000170393

chr8_+_14158021 0.28 ENSDART00000080832
si:dkey-6n6.2
chr6_+_26346686 0.28 ENSDART00000154183
DAZ interacting zinc finger protein 1-like
chr6_+_3280939 0.28 ENSDART00000151359
lysine (K)-specific demethylase 4A, genome duplicate a
chr17_-_17764801 0.27 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr3_+_62196672 0.27 ENSDART00000097312
SCO1 cytochrome c oxidase assembly protein
chr19_+_46095210 0.27 ENSDART00000159753
stathmin domain containing 1
chr21_-_45073764 0.27 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr4_-_8152746 0.27 ENSDART00000012928
ENSDART00000177482
WNK lysine deficient protein kinase 1b
chr12_+_49135755 0.27 ENSDART00000153460
si:zfos-911d5.4
chr13_-_37127970 0.27 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr21_-_11856143 0.27 ENSDART00000151204
ubiquitin-conjugating enzyme E2R 2
chr2_-_23931536 0.27 ENSDART00000121885
transforming growth factor, beta receptor 1 a
chr23_+_21638258 0.27 ENSDART00000104188
immunoglobin superfamily, member 21b
chr5_-_69523816 0.27 ENSDART00000112692
si:ch211-157p22.10
chr18_+_50801307 0.26 ENSDART00000174126
tetraspanin 4a
chr24_-_37003577 0.26 ENSDART00000137777
dynein, axonemal, assembly factor 3
chr8_-_48675775 0.26 ENSDART00000060785
Pim proto-oncogene, serine/threonine kinase, related 183
chr13_-_36418921 0.26 ENSDART00000135804
ddb1 and cul4 associated factor 5
chr24_-_8777781 0.26 ENSDART00000082362
ENSDART00000177400
male germ cell-associated kinase
chr5_+_54400971 0.26 ENSDART00000169695
B-box and SPRY domain containing
chr21_-_8420830 0.25 ENSDART00000138040
LIM homeobox 2a
chr25_-_3469576 0.25 ENSDART00000186738
HMG-box transcription factor 1
chr20_-_16906623 0.25 ENSDART00000012859
ENSDART00000171628
proteasome subunit alpha 6b
chr20_-_43459761 0.25 ENSDART00000137422
Pim proto-oncogene, serine/threonine kinase, related 133
chr23_+_9560991 0.25 ENSDART00000081433
ENSDART00000131594
ENSDART00000130069
ENSDART00000138601
adhesion regulating molecule 1
chr17_-_46933567 0.25 ENSDART00000157274
Pim proto-oncogene, serine/threonine kinase, related 25
chr14_+_45732081 0.25 ENSDART00000110103
coiled-coil domain containing 88B
chr22_-_35330532 0.25 ENSDART00000172654

chr7_+_21331688 0.25 ENSDART00000128014
dynein, axonemal, heavy chain 2
chr25_+_13731726 0.25 ENSDART00000181065
coiled-coil domain containing 135
chr5_-_3889047 0.25 ENSDART00000185817
MLX interacting protein like
chr2_+_33051730 0.24 ENSDART00000177902
ENSDART00000187903
ring finger protein 220a
chr25_+_3327071 0.24 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr5_+_13353866 0.24 ENSDART00000099611
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr22_+_18816662 0.24 ENSDART00000132476
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr19_+_3826782 0.24 ENSDART00000169222
organic solute carrier partner 1a
chr13_+_51981764 0.24 ENSDART00000160698
kelch domain containing 3
chr18_+_7594012 0.24 ENSDART00000062150
zgc:77752
chr11_-_6048490 0.24 ENSDART00000066164
plasmalemma vesicle associated protein b
chr3_-_30941362 0.24 ENSDART00000076830
coronin, actin binding protein, 1A
chr23_+_9560797 0.24 ENSDART00000180014
adhesion regulating molecule 1
chr7_-_59256806 0.24 ENSDART00000167955
meiosis 1 associated protein
chr20_-_40717900 0.24 ENSDART00000181663
connexin 43
chr1_-_9109699 0.23 ENSDART00000147833
vascular associated protein
chr2_-_42960353 0.23 ENSDART00000098303
otoconin 90
chr20_-_14924858 0.23 ENSDART00000047039
dynamin 3a
chr1_+_44767657 0.23 ENSDART00000073717
si:dkey-9i23.4
chrM_+_9735 0.23 ENSDART00000093613
cytochrome c oxidase III, mitochondrial
chr10_-_17103651 0.23 ENSDART00000108959
ring finger protein 208
chr19_+_712127 0.23 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
formin homology 2 domain containing 3a
chr12_+_18532866 0.23 ENSDART00000152126
ENSDART00000152443
ENSDART00000089589
meiosis specific with OB domains
chr1_-_8691969 0.23 ENSDART00000152153
ATP-binding cassette, sub-family G (WHITE), member 2b
chr8_-_48675411 0.22 ENSDART00000165081
Pim proto-oncogene, serine/threonine kinase, related 183
chr5_+_483965 0.22 ENSDART00000150007
TEK tyrosine kinase, endothelial
chr19_+_4916233 0.22 ENSDART00000159512
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_+_56213694 0.22 ENSDART00000162582
upf1 regulator of nonsense transcripts homolog (yeast)
chr7_+_40884012 0.22 ENSDART00000149395
sonic hedgehog a
chr7_+_22293894 0.22 ENSDART00000056790
transmembrane protein 256
chr23_+_2760573 0.22 ENSDART00000129719
DNA topoisomerase I
chr1_+_12046544 0.22 ENSDART00000152479
si:dkey-58j15.11
chr5_-_36549024 0.22 ENSDART00000097671
zgc:158432
chr24_-_5910811 0.22 ENSDART00000163012
procollagen C-endopeptidase enhancer 2b
chr3_-_41292275 0.22 ENSDART00000144088
sidekick cell adhesion molecule 1a
chr17_+_53156530 0.22 ENSDART00000126277
ENSDART00000156774
diphthamine biosynthesis 6
chr3_-_36260102 0.22 ENSDART00000126588
Rac family small GTPase 3a
chr14_+_17376940 0.22 ENSDART00000054590
ENSDART00000010148
spondin 2b, extracellular matrix protein
chr6_+_52350443 0.21 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr18_+_3530769 0.21 ENSDART00000163469
si:ch73-338a16.3
chr21_+_11415224 0.21 ENSDART00000049036
zgc:92275
chr19_+_58954 0.21 ENSDART00000162379
collagen, type XIV, alpha 1b
chr5_-_3839285 0.21 ENSDART00000122292
MLX interacting protein like
chr6_+_10871659 0.21 ENSDART00000041858
metaxin 2
chr6_+_10450000 0.21 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
potassium channel, voltage gated eag related subfamily H, member 7
chr1_+_50976975 0.21 ENSDART00000022290
ENSDART00000140982
malate dehydrogenase 1Aa, NAD (soluble)
chr2_-_127945 0.21 ENSDART00000056453
insulin-like growth factor binding protein 1b
chr17_+_32374876 0.21 ENSDART00000183851
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr12_-_37653685 0.21 ENSDART00000085121
sidekick cell adhesion molecule 2b
chr14_+_17397534 0.20 ENSDART00000180162
ENSDART00000129838
ring finger protein 212
chr22_+_10201826 0.20 ENSDART00000006513
ENSDART00000132641
pyruvate dehydrogenase E1 beta subunit
chr15_-_23793641 0.20 ENSDART00000122891
transmembrane protein 97
chr9_-_20372977 0.20 ENSDART00000113418
immunoglobulin superfamily, member 3
chr16_-_45327616 0.20 ENSDART00000158733
si:dkey-33i11.1
chr6_+_9651703 0.20 ENSDART00000122937
transcription factor 23
chr24_-_25186895 0.20 ENSDART00000081029
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr16_+_21242491 0.20 ENSDART00000145886
oxysterol binding protein-like 3b
chr2_+_49864219 0.20 ENSDART00000187744
ribosomal protein L37
chr18_-_15932704 0.20 ENSDART00000127769
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr23_+_44633858 0.20 ENSDART00000180728
si:ch73-265d7.2
chr16_-_2558653 0.20 ENSDART00000110365
adenylate cyclase 3a
chr21_+_44112914 0.20 ENSDART00000062836
fibroblast growth factor 1b
chr16_+_4839078 0.19 ENSDART00000150111
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr5_-_72376973 0.19 ENSDART00000164969

chr18_-_48550426 0.19 ENSDART00000145189
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr10_-_27566481 0.19 ENSDART00000078920
autism susceptibility candidate 2a
chr6_-_37468971 0.19 ENSDART00000126379
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr13_-_50108337 0.19 ENSDART00000133308
nidogen 1a
chr12_+_30234209 0.19 ENSDART00000102081
actin filament associated protein 1-like 2
chr20_-_4731155 0.19 ENSDART00000152155
poly(A) polymerase alpha
chr8_-_13471916 0.19 ENSDART00000146558
Pim proto-oncogene, serine/threonine kinase, related 105
chr17_+_53425037 0.19 ENSDART00000154983
fatty acid binding protein 10b, liver basic
chr13_+_15354012 0.19 ENSDART00000121453
lysyl oxidase-like 3b

Network of associatons between targets according to the STRING database.

First level regulatory network of esr1+esr2a+esr2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 0.5 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.4 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.1 1.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.9 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.3 GO:0090220 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.3 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 0.3 GO:0032369 negative regulation of lipid transport(GO:0032369) negative regulation of lipid catabolic process(GO:0050995)
0.1 0.3 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.5 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.1 0.4 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.1 0.4 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 0.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.8 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0007440 foregut morphogenesis(GO:0007440)
0.1 0.2 GO:0032602 chemokine production(GO:0032602)
0.1 0.4 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.1 0.3 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 0.2 GO:0055026 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.1 0.2 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0072149 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.2 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.0 0.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:0044003 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.2 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.2 GO:1990544 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.2 GO:2000316 regulation of T-helper 17 type immune response(GO:2000316) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.7 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) response to dexamethasone(GO:0071548)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.5 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.1 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.2 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.4 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.1 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.0 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.7 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.1 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868)
0.0 0.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.7 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0030317 sperm motility(GO:0030317)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0016122 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 0.3 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 1.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 4.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.0 0.0 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.0 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:1901381 positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 0.0 GO:0072020 proximal straight tubule development(GO:0072020)
0.0 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:1900744 regulation of p38MAPK cascade(GO:1900744)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.5 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.3 GO:0000801 central element(GO:0000801)
0.1 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.1 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 1.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.0 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 1.3 GO:0005930 axoneme(GO:0005930)
0.0 0.3 GO:0070469 respiratory chain(GO:0070469)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0097546 ciliary base(GO:0097546)
0.0 0.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0098533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.8 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.5 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.2 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.2 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.3 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.0 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.0 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.1 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:2001070 starch binding(GO:2001070)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.0 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling