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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for eomesa
Z-value: 1.39
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Transcription factors associated with eomesa
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| eomesa | dr11_v1_chr19_-_868187_868187 | 0.61 | 7.3e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_+_19596214 Show fit | 6.17 |
ENSDART00000183110
|
|
|
| chr19_-_27564458 Show fit | 5.54 |
ENSDART00000123155
|
si:dkeyp-46h3.6 |
|
| chr22_+_25704430 Show fit | 4.23 |
ENSDART00000143776
|
si:dkeyp-98a7.3 |
|
| chr22_+_25687525 Show fit | 4.22 |
ENSDART00000135717
|
si:dkeyp-98a7.3 |
|
| chr22_+_25681911 Show fit | 4.22 |
ENSDART00000113381
|
si:dkeyp-98a7.3 |
|
| chr10_+_19595009 Show fit | 4.14 |
ENSDART00000112276
|
zgc:173837 |
|
| chr22_+_25693295 Show fit | 4.14 |
ENSDART00000123888
ENSDART00000150783 |
si:dkeyp-98a7.4 si:dkeyp-98a7.3 |
|
| chr22_+_25715925 Show fit | 4.10 |
ENSDART00000150650
|
si:dkeyp-98a7.7 |
|
| chr22_+_25753972 Show fit | 4.05 |
ENSDART00000188417
|
|
|
| chr22_+_25352530 Show fit | 3.97 |
ENSDART00000176742
ENSDART00000113186 |
si:dkey-240e12.6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of eomesa
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 1.0 | 3.0 | GO:0060571 | invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571) |
| 0.2 | 1.6 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
| 0.1 | 1.5 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.1 | 1.3 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.1 | 1.3 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) response to copper ion(GO:0046688) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.2 | 1.2 | GO:0031174 | lifelong otolith mineralization(GO:0031174) |
| 0.2 | 1.2 | GO:0070640 | vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305) |
| 0.0 | 1.2 | GO:0031101 | fin regeneration(GO:0031101) |
| 0.0 | 1.1 | GO:0043534 | blood vessel endothelial cell migration(GO:0043534) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.0 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.3 | 1.6 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
| 0.0 | 1.3 | GO:0031970 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.0 | 1.2 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.8 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.1 | 0.7 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 0.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.6 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 0.3 | GO:0034657 | GID complex(GO:0034657) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 30.4 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.2 | 3.5 | GO:0061608 | nuclear import signal receptor activity(GO:0061608) |
| 0.0 | 2.5 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 2.2 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.4 | 1.6 | GO:0030366 | molybdopterin synthase activity(GO:0030366) |
| 0.1 | 1.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.3 | 1.3 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.3 | 1.3 | GO:0070004 | cysteine-type exopeptidase activity(GO:0070004) |
| 0.0 | 1.3 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
| 0.3 | 1.2 | GO:0051717 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 2.2 | PID FOXO PATHWAY | FoxO family signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 1.3 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 1.2 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 0.8 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.7 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 0.1 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 0.1 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.0 | 0.1 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |