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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for elf3

Z-value: 0.45

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Transcription factors associated with elf3

Gene Symbol Gene ID Gene Info
ENSDARG00000077982 E74-like factor 3 (ets domain transcription factor, epithelial-specific )

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
elf3dr11_v1_chr22_+_661711_6617110.599.4e-03Click!

Activity profile of elf3 motif

Sorted Z-values of elf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_28727383 0.96 ENSDART00000149753
DC-STAMP domain containing 2
chr13_-_23074454 0.90 ENSDART00000065652
serglycin
chr5_+_42467867 0.84 ENSDART00000172028
Pim proto-oncogene, serine/threonine kinase, related 58
chr20_-_43572763 0.78 ENSDART00000153251
Pim proto-oncogene, serine/threonine kinase, related 125
chr1_+_40237276 0.65 ENSDART00000037553
fatty acid amide hydrolase 2a
chr9_-_48397702 0.63 ENSDART00000147169
zgc:172182
chr13_+_33304187 0.63 ENSDART00000075826
ENSDART00000145295
doublecortin domain containing 2B
chr17_-_10309766 0.61 ENSDART00000160994
tetratricopeptide repeat domain 6
chr3_-_32902138 0.54 ENSDART00000144026
ENSDART00000083874
ENSDART00000145443
ENSDART00000148239
ENSDART00000134917
K(lysine) acetyltransferase 7a
chr1_-_59252973 0.54 ENSDART00000167061
si:ch1073-286c18.5
chr22_-_36934040 0.53 ENSDART00000151666
Pim proto-oncogene, serine/threonine kinase, related 206
chr5_-_21524251 0.48 ENSDART00000176793
ENSDART00000040184
teneurin transmembrane protein 1
chr6_-_55254786 0.48 ENSDART00000113805
nuclear factor of activated T cells 2b
chr20_+_42761881 0.47 ENSDART00000113625
Pim proto-oncogene, serine/threonine kinase, related 113
chr5_+_42402536 0.47 ENSDART00000186754

chr6_-_17849786 0.47 ENSDART00000172709
regulatory associated protein of MTOR, complex 1
chr23_-_10175898 0.46 ENSDART00000146185
keratin 5
chr3_+_49576662 0.46 ENSDART00000162275

chr20_+_39457598 0.46 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr2_+_9061885 0.45 ENSDART00000028906
phosphatidylinositol glycan anchor biosynthesis, class K
chr7_-_22981796 0.44 ENSDART00000167565
si:dkey-171c9.3
chr11_-_38899816 0.43 ENSDART00000141515
Pim proto-oncogene, serine/threonine kinase, related 127
chr12_-_28910419 0.43 ENSDART00000153278
ENSDART00000152937
si:ch73-81k8.2
chr17_-_12407106 0.42 ENSDART00000183540
ankyrin repeat and EF-hand domain containing 1b
chr11_+_11842724 0.42 ENSDART00000163752
Pim proto-oncogene, serine/threonine kinase, related 94
chr20_+_34770197 0.41 ENSDART00000018304
minichromosome maintenance complex component 3
chr22_+_12798569 0.40 ENSDART00000005720
signal transducer and activator of transcription 1a
chr20_+_33739059 0.40 ENSDART00000140361
peptidylprolyl isomerase (cyclophilin)-like 6
chr20_-_43495506 0.40 ENSDART00000170679
Pim proto-oncogene, serine/threonine kinase, related 132
chr5_-_57652168 0.40 ENSDART00000166245
expressed sequence EH456644
chr1_-_14258409 0.39 ENSDART00000079359
phosphodiesterase 5A, cGMP-specific, a
chr5_+_37087583 0.39 ENSDART00000049900
transgelin 2
chr5_-_26834511 0.39 ENSDART00000136713
ENSDART00000192932
ENSDART00000113246
si:ch211-102c2.4
chr5_-_55623443 0.38 ENSDART00000005671
ENSDART00000176341
heterogeneous nuclear ribonucleoprotein K, like
chr8_+_11642070 0.38 ENSDART00000004288
intraflagellar transport 81 homolog
chr3_+_29942338 0.38 ENSDART00000158220
interferon-induced protein 35
chr4_-_41209037 0.37 ENSDART00000151948
si:ch211-73m21.1
chr13_-_5978433 0.37 ENSDART00000102555
ARP2 actin related protein 2b homolog
chr4_-_64284924 0.37 ENSDART00000166733

chr6_+_40714811 0.37 ENSDART00000153868
coiled-coil domain containing 36
chr17_-_681142 0.36 ENSDART00000165583
heme-binding protein soul3
chr1_+_22691256 0.35 ENSDART00000017413
zinc finger, MYND-type containing 10
chr23_-_45318760 0.35 ENSDART00000166883
coiled-coil domain containing 171
chr8_+_8947623 0.34 ENSDART00000131215
solute carrier family 35 (UDP-galactose transporter), member 2
chr20_+_42780162 0.33 ENSDART00000127069
Pim proto-oncogene, serine/threonine kinase, related 213
chr1_-_59407322 0.33 ENSDART00000161661
si:ch211-188p14.5
chr10_+_40324395 0.33 ENSDART00000147205
glycolipid transfer protein b
chr19_+_18758014 0.32 ENSDART00000158935
chloride intracellular channel 1
chr24_+_9590188 0.32 ENSDART00000137092
si:dkey-96n2.1
chr5_-_23464970 0.31 ENSDART00000141028
si:dkeyp-20g2.1
chr3_+_46479705 0.31 ENSDART00000181564
tyrosine kinase 2
chr17_-_19626357 0.31 ENSDART00000011432
receptor accessory protein 3a
chr8_-_11202378 0.31 ENSDART00000147817
ENSDART00000174039
family with sequence similarity 208, member B
chr21_-_45073764 0.31 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr14_+_6287871 0.31 ENSDART00000105344
TBC1 domain family, member 2
chr3_+_26064091 0.31 ENSDART00000143697
si:dkeyp-69e1.8
chr1_-_625875 0.31 ENSDART00000167331
amyloid beta (A4) precursor protein a
chr1_-_11104805 0.31 ENSDART00000147648
kinetochore scaffold 1
chr22_+_29067388 0.30 ENSDART00000133673
Pim proto-oncogene, serine/threonine kinase, related 100
chr1_+_51386649 0.29 ENSDART00000152289
autophagy related 4D, cysteine peptidase a
chr25_-_35664817 0.29 ENSDART00000148718
leucine-rich repeat kinase 2
chr3_-_5228137 0.29 ENSDART00000137105
myosin, heavy chain 9b, non-muscle
chr20_+_43602810 0.28 ENSDART00000142543
si:dkey-206f10.1
chr23_-_40788933 0.27 ENSDART00000086613
si:dkeyp-27c8.1
chr7_-_24204665 0.27 ENSDART00000167141
guanosine monophosphate reductase 2
chr16_+_29514473 0.27 ENSDART00000034102
cathepsin S, ortholog 2, tandem duplicate 2
chr11_+_13423776 0.27 ENSDART00000102553
homer scaffolding protein 3b
chr2_-_30249746 0.27 ENSDART00000124153
ENSDART00000142575
elongin C paralog b
chr3_+_24459709 0.27 ENSDART00000180976
chromobox homolog 6b
chr11_-_18601955 0.26 ENSDART00000180565
zinc finger, MYND-type containing 8
chr3_-_15080226 0.26 ENSDART00000109818
ENSDART00000139835
NME/NM23 nucleoside diphosphate kinase 4
chr17_-_5610514 0.26 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr3_+_34234029 0.26 ENSDART00000044859
zinc finger protein 207, a
chr6_-_12459412 0.25 ENSDART00000090266
ENSDART00000144028
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr5_-_29152457 0.24 ENSDART00000078469
NADPH oxidase activator 1
chr8_+_50742975 0.24 ENSDART00000155664
ENSDART00000160612
si:ch73-6l19.2
chr8_-_41264502 0.24 ENSDART00000133124
ring finger protein 10
chr24_-_35707552 0.23 ENSDART00000165199
microtubule-associated protein, RP/EB family, member 2
chr19_-_20403845 0.23 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
deleted in azoospermia-like
chr9_+_2499627 0.23 ENSDART00000160782
WAS/WASL interacting protein family, member 1a
chr3_+_46479913 0.22 ENSDART00000149755
tyrosine kinase 2
chr6_+_26309968 0.22 ENSDART00000153805
DAZ interacting zinc finger protein 1-like
chr17_+_46739693 0.22 ENSDART00000097810
Pim proto-oncogene, serine/threonine kinase, related 22
chr4_-_37766174 0.22 ENSDART00000170066
si:dkey-207l24.2
chr4_+_2655358 0.22 ENSDART00000007638
B cell receptor associated protein 29
chr23_-_42810664 0.22 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr7_-_31759602 0.21 ENSDART00000113467
immunoglobulin superfamily, DCC subclass, member 4
chr5_+_40835601 0.21 ENSDART00000147767
si:dkey-3h3.3
chr15_-_2010926 0.21 ENSDART00000155688
dedicator of cytokinesis 10
chr14_-_26436951 0.21 ENSDART00000140173
si:dkeyp-110e4.6
chr12_+_16452912 0.21 ENSDART00000192467
kinesin family member 20Bb
chr23_+_1181248 0.21 ENSDART00000170942
utrophin
chr19_-_19442983 0.21 ENSDART00000052649
sb:cb649
chr3_-_57779801 0.21 ENSDART00000074285
synaptogyrin 2a
chr9_+_12948511 0.21 ENSDART00000135797
si:dkey-230p4.1
chr17_-_11418513 0.21 ENSDART00000064412
ENSDART00000151847
AT rich interactive domain 4A (RBP1-like)
chr3_-_34337969 0.20 ENSDART00000151634
trinucleotide repeat containing 6C1
chr1_+_36722122 0.20 ENSDART00000111566
transmembrane protein 184C
chr1_+_2101541 0.20 ENSDART00000128187
ENSDART00000167050
ENSDART00000182153
ENSDART00000122626
ENSDART00000164488
muscleblind-like splicing regulator 2
chr20_-_22798794 0.20 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr4_-_17642168 0.20 ENSDART00000007030
kelch-like family, member 42
chr18_+_20677090 0.20 ENSDART00000060243
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr20_-_2090789 0.20 ENSDART00000113237
Rho GTPase activating protein 18
chr11_+_34760628 0.20 ENSDART00000087216
si:dkey-202e22.2
chr1_+_55293424 0.19 ENSDART00000152464
zgc:172106
chr3_-_5228841 0.19 ENSDART00000092373
ENSDART00000182438
myosin, heavy chain 9b, non-muscle
chr6_+_3282809 0.19 ENSDART00000187444
ENSDART00000187407
ENSDART00000191883
lysine (K)-specific demethylase 4A, genome duplicate a
chr7_+_22981441 0.19 ENSDART00000182887
cyclin B3
chr4_-_17263210 0.19 ENSDART00000147853
lymphoid-restricted membrane protein
chr13_-_44738574 0.18 ENSDART00000074761
zinc finger, AN1-type domain 3
chr8_+_13694950 0.18 ENSDART00000132506
Pim proto-oncogene, serine/threonine kinase, related 107
chr8_+_35964482 0.18 ENSDART00000129357
ENSDART00000154953
glycosyltransferase 1 domain containing 1
chr15_-_1534232 0.18 ENSDART00000056763
ENSDART00000133943
intraflagellar transport 80 homolog (Chlamydomonas)
chr1_+_10318089 0.18 ENSDART00000029774
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr3_+_57997980 0.18 ENSDART00000168477
ENSDART00000193840
pyrroline-5-carboxylate reductase 1a
chr22_+_29009541 0.18 ENSDART00000169449
Pim proto-oncogene, serine/threonine kinase, related 97
chr11_+_45343245 0.18 ENSDART00000160904
si:ch73-100l22.3
chr2_+_27651984 0.18 ENSDART00000126762
transmembrane protein 68
chr8_-_13315304 0.18 ENSDART00000142596
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b
chr9_-_49860756 0.18 ENSDART00000044270
tetratricopeptide repeat domain 21B
chr7_-_31759394 0.17 ENSDART00000193040
immunoglobulin superfamily, DCC subclass, member 4
chr12_+_34763795 0.17 ENSDART00000153097
solute carrier family 38, member 10
chr19_+_25476228 0.17 ENSDART00000112808
collagen, type XXVIII, alpha 1a
chr21_+_25198637 0.17 ENSDART00000164972
si:dkey-183i3.6
chr1_+_55294009 0.17 ENSDART00000128979
zgc:172106
chr8_+_15239549 0.17 ENSDART00000132216
polyamine oxidase (exo-N4-amino) 1
chr5_-_39171302 0.17 ENSDART00000020808
progestin and adipoQ receptor family member IIIa
chr4_-_17353100 0.16 ENSDART00000134467
ENSDART00000189019
PARP1 binding protein
chr13_+_34689663 0.16 ENSDART00000133661
taspase, threonine aspartase, 1
chr8_+_53423408 0.16 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr13_+_27316934 0.16 ENSDART00000164533
eukaryotic translation elongation factor 1 alpha 1a
chr7_+_31051603 0.16 ENSDART00000108721
tight junction protein 1a
chr15_-_8856391 0.16 ENSDART00000008273
RAB4B, member RAS oncogene family
chr25_-_32311048 0.16 ENSDART00000181806
ENSDART00000086334

chr1_-_47071979 0.15 ENSDART00000160817
intersectin 1 (SH3 domain protein)
chr11_-_141592 0.15 ENSDART00000092787
cyclin-dependent kinase 4
chr12_+_33395748 0.15 ENSDART00000129458
fatty acid synthase
chr4_+_14727212 0.15 ENSDART00000158094
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr6_-_442163 0.15 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
GRB2-related adaptor protein 2b
chr2_+_27652386 0.15 ENSDART00000188261
transmembrane protein 68
chr1_-_24349759 0.15 ENSDART00000142740
ENSDART00000177989
LPS-responsive vesicle trafficking, beach and anchor containing
chr2_+_17524278 0.15 ENSDART00000165633
Pim proto-oncogene, serine/threonine kinase, related 196
chr7_+_19374683 0.15 ENSDART00000162700
small nuclear ribonucleoprotein polypeptide F
chr15_+_21882419 0.14 ENSDART00000157216
si:dkey-103g5.4
chr5_-_31875645 0.14 ENSDART00000098160
transmembrane protein 119b
chr12_-_7824291 0.14 ENSDART00000148673
ENSDART00000149453
ankyrin 3b
chr6_-_8489810 0.14 ENSDART00000124643
RAS protein activator like 3
chr5_+_65946222 0.14 ENSDART00000190969
ENSDART00000161578
myomaker, myoblast fusion factor
chr23_+_42304602 0.14 ENSDART00000166004
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr15_+_9327252 0.14 ENSDART00000144381
sarcoglycan, gamma
chr22_-_30973791 0.14 ENSDART00000104728
ssu-2 homolog, tandem duplicate 2
chr4_-_9533345 0.14 ENSDART00000128501
si:ch73-139j3.4
chr7_+_22981909 0.13 ENSDART00000122449
cyclin B3
chr11_-_29816429 0.13 ENSDART00000069132
cytochrome b-245, beta polypeptide (chronic granulomatous disease)
chr3_-_9458445 0.13 ENSDART00000192712

chr3_+_24612191 0.13 ENSDART00000190998
zgc:171506
chr22_-_3595439 0.13 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr7_-_6351021 0.13 ENSDART00000159542
zgc:112234
chr20_+_32478151 0.13 ENSDART00000145269
osteopetrosis associated transmembrane protein 1
chr1_+_12767318 0.13 ENSDART00000162652
protocadherin 10a
chr20_-_33556983 0.13 ENSDART00000168798
rho-associated, coiled-coil containing protein kinase 2b, like
chr16_-_12723738 0.13 ENSDART00000080414
SH3 domain binding kinase family, member 3
chr4_-_12723585 0.13 ENSDART00000185639
microsomal glutathione S-transferase 1.2
chr24_+_37449893 0.13 ENSDART00000164405
NLR family, CARD domain containing 3
chr10_-_26766780 0.13 ENSDART00000146666
MCF.2 cell line derived transforming sequence b
chr22_+_1170294 0.13 ENSDART00000159761
ENSDART00000169809
interferon regulatory factor 6
chr12_-_14551077 0.13 ENSDART00000188717

chr8_+_22438398 0.12 ENSDART00000135145
zgc:153759
chr13_+_28705143 0.12 ENSDART00000183338
LIM domain binding 1a
chr21_+_21244046 0.12 ENSDART00000058306
ENSDART00000189665
ENSDART00000131890
leukemia inhibitory factor receptor alpha b
chr1_-_35924495 0.12 ENSDART00000184424
SMAD family member 1
chr8_-_46321889 0.12 ENSDART00000075189
ENSDART00000122801
mechanistic target of rapamycin kinase
chr8_+_48801402 0.12 ENSDART00000098363
tumor protein p63 regulated 1-like
chr15_+_15856178 0.12 ENSDART00000080338
dual specificity phosphatase 14
chr21_-_2217685 0.12 ENSDART00000159315
si:dkey-50i6.5
chr6_+_18298444 0.12 ENSDART00000166018
caspase recruitment domain family, member 14
chr3_-_50277959 0.12 ENSDART00000082773
ENSDART00000139524
ADP-ribosylation factor-like 16
chr24_-_11069237 0.12 ENSDART00000127398

chr11_-_38914265 0.12 ENSDART00000141229
si:ch211-122l14.4
chr15_+_15415623 0.11 ENSDART00000127436
zgc:92630
chr3_-_21061931 0.11 ENSDART00000036741
family with sequence similarity 57, member Ba
chr1_+_157793 0.11 ENSDART00000152205
cullin 4A
chr19_+_48373140 0.11 ENSDART00000160896
abhydrolase domain containing 5b
chr17_+_24222190 0.11 ENSDART00000181698
ENSDART00000189411
EH domain binding protein 1
chr15_+_1534644 0.11 ENSDART00000130413
structural maintenance of chromosomes 4
chr15_+_3808996 0.11 ENSDART00000110227
ring finger protein 14
chr4_+_9911534 0.11 ENSDART00000109452
SET binding factor 1
chr16_+_13855039 0.11 ENSDART00000113764
ENSDART00000143983
zgc:174888
chr7_+_35075847 0.11 ENSDART00000193469
ENSDART00000037346
chymotrypsinogen B1
chr7_-_56766973 0.11 ENSDART00000020967
casein kinase 2, alpha prime polypeptide a
chr25_-_34979548 0.10 ENSDART00000153904
si:dkey-108k21.7
chr4_-_12978925 0.10 ENSDART00000013839
transmembrane BAX inhibitor motif containing 4
chr4_-_22310956 0.10 ENSDART00000162585
hematopoietic cell-specific Lyn substrate 1
chr23_-_9965148 0.10 ENSDART00000137308
plexin b1a
chr3_-_11972516 0.10 ENSDART00000140123
heme oxygenase 2b
chr22_-_16377960 0.10 ENSDART00000168170
tetratricopeptide repeat domain 39C
chr24_-_32025637 0.10 ENSDART00000180448
ENSDART00000159034
Ras suppressor protein 1
chr13_+_30696286 0.10 ENSDART00000192411
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr15_-_8856785 0.10 ENSDART00000192816
RAB4B, member RAS oncogene family
chr20_-_33705044 0.10 ENSDART00000166573
rho-associated, coiled-coil containing protein kinase 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of elf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0035046 pronuclear migration(GO:0035046)
0.1 0.4 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.3 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.4 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.4 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.6 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.3 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.1 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.4 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.6 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.0 GO:0045191 regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 5.8 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.0 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.0 0.1 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.5 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.3 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins