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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for e4f1+si:dkeyp-79b7.12

Z-value: 0.68

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Transcription factors associated with e4f1+si:dkeyp-79b7.12

Gene Symbol Gene ID Gene Info
e4f1
ENSDARG00000038243 E4F transcription factor 1
si_dkeyp-79b7.12
ENSDARG00000105305 si_dkeyp-79b7.12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
e4f1dr11_v1_chr3_-_18737126_187371260.912.1e-07Click!
si:dkeyp-79b7.12dr11_v1_chr22_+_2207502_22075020.455.9e-02Click!

Activity profile of e4f1+si:dkeyp-79b7.12 motif

Sorted Z-values of e4f1+si:dkeyp-79b7.12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_44801968 2.07 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr22_-_10541712 1.58 ENSDART00000013933
si:dkey-42i9.4
si:dkey-42i9.4
chr10_-_44017642 1.54 ENSDART00000135240
ENSDART00000014669
acads
acyl-CoA dehydrogenase short chain
chr17_+_25187226 1.53 ENSDART00000148431
cln8
CLN8, transmembrane ER and ERGIC protein
chr22_-_10541372 1.38 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr7_-_26518086 1.30 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr5_-_29531948 1.29 ENSDART00000098360
arrdc1a
arrestin domain containing 1a
chr20_-_44576949 1.29 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr2_+_9821757 1.28 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
anxa13l
annexin A13, like
chr5_+_44846434 1.27 ENSDART00000145299
ENSDART00000136521
kank1a
KN motif and ankyrin repeat domains 1a
chr5_+_44846280 1.26 ENSDART00000084370
kank1a
KN motif and ankyrin repeat domains 1a
chr7_+_66634167 1.22 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr2_-_10386738 1.14 ENSDART00000016369
wls
wntless Wnt ligand secretion mediator
chr9_+_33334501 1.13 ENSDART00000006867
ddx3a
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr8_-_410199 1.12 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr8_-_410728 1.09 ENSDART00000151255
trim36
tripartite motif containing 36
chr14_+_30413312 1.09 ENSDART00000186864
cnot7
CCR4-NOT transcription complex, subunit 7
chr15_+_20239141 1.08 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr6_+_112579 1.08 ENSDART00000034505
ap1m2
adaptor-related protein complex 1, mu 2 subunit
chr13_-_8304605 1.08 ENSDART00000080460
atl2
atlastin GTPase 2
chr12_+_33320884 1.02 ENSDART00000188988
csnk1db
casein kinase 1, delta b
chr25_-_34845302 1.02 ENSDART00000039485
gabarapl2
GABA(A) receptor-associated protein like 2
chr5_-_25576462 1.01 ENSDART00000165147
si:dkey-229d2.4
si:dkey-229d2.4
chr8_-_19266325 0.98 ENSDART00000036148
ENSDART00000137994
zgc:77486
zgc:77486
chr9_+_34148714 0.93 ENSDART00000078051
gpr161
G protein-coupled receptor 161
chr19_-_20106486 0.93 ENSDART00000043924
mpp6b
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr4_+_9011825 0.90 ENSDART00000058007
samm50l
sorting and assembly machinery component 50 homolog, like
chr10_+_44903676 0.89 ENSDART00000158553
zgc:114173
zgc:114173
chr23_-_32157865 0.89 ENSDART00000000876
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr23_-_17509656 0.89 ENSDART00000148423
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr3_-_21137362 0.88 ENSDART00000104051
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr25_-_23052707 0.88 ENSDART00000024633
dusp8a
dual specificity phosphatase 8a
chr2_+_9560740 0.86 ENSDART00000003465
gipc2
GIPC PDZ domain containing family, member 2
chr12_+_33320504 0.86 ENSDART00000021491
csnk1db
casein kinase 1, delta b
chr15_-_27522387 0.84 ENSDART00000112643
brip1
BRCA1 interacting protein C-terminal helicase 1
chr4_+_9011448 0.84 ENSDART00000192357
samm50l
sorting and assembly machinery component 50 homolog, like
chr17_+_1544903 0.83 ENSDART00000156244
ENSDART00000112183
cep170b
centrosomal protein 170B
chr4_-_12930086 0.83 ENSDART00000013604
lemd3
LEM domain containing 3
chr5_+_58455488 0.81 ENSDART00000038602
ENSDART00000127958
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr9_-_11655031 0.81 ENSDART00000044314
itgav
integrin, alpha V
chr14_+_1170968 0.80 ENSDART00000125203
ENSDART00000193575
hopx
HOP homeobox
chr20_-_36671660 0.80 ENSDART00000134819
slc5a6a
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6a
chr15_-_27522806 0.77 ENSDART00000149374
ENSDART00000187341
ENSDART00000183043
ENSDART00000189541
ENSDART00000190362
ENSDART00000193745
ENSDART00000187390
brip1
BRCA1 interacting protein C-terminal helicase 1
chr19_-_3821678 0.74 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr23_-_29668286 0.74 ENSDART00000129248
clstn1
calsyntenin 1
chr15_-_41689981 0.74 ENSDART00000059327
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr23_+_33963619 0.73 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr18_+_38775277 0.71 ENSDART00000186129
fam214a
family with sequence similarity 214, member A
chr5_+_26921033 0.71 ENSDART00000051483
tm2d2
TM2 domain containing 2
chr16_-_41535690 0.71 ENSDART00000102662
rpp25l
ribonuclease P/MRP 25 subunit-like
chr8_+_49433663 0.69 ENSDART00000140481
ENSDART00000180714
nfu1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr9_-_54840124 0.69 ENSDART00000137214
ENSDART00000085693
gpm6bb
glycoprotein M6Bb
chr15_-_8309207 0.68 ENSDART00000143880
ENSDART00000061351
tnfrsf19
tumor necrosis factor receptor superfamily, member 19
chr12_-_34852342 0.68 ENSDART00000152968
si:dkey-21c1.1
si:dkey-21c1.1
chr14_+_30413758 0.68 ENSDART00000092953
cnot7
CCR4-NOT transcription complex, subunit 7
chr3_+_61221194 0.68 ENSDART00000110030
lmtk2
lemur tyrosine kinase 2
chr15_-_23721618 0.67 ENSDART00000109318
zc3h4
zinc finger CCCH-type containing 4
chr23_-_27505825 0.67 ENSDART00000137229
ENSDART00000013797
asb8
ankyrin repeat and SOCS box containing 8
chr23_-_10722664 0.67 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
foxp1a
forkhead box P1a
chr2_-_4032732 0.66 ENSDART00000158335
rab18b
RAB18B, member RAS oncogene family
chr15_-_1843831 0.66 ENSDART00000156718
ENSDART00000154175
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr24_-_37326236 0.65 ENSDART00000003789
pdpk1b
3-phosphoinositide dependent protein kinase 1b
chr20_+_36812368 0.64 ENSDART00000062931
abracl
ABRA C-terminal like
chr1_-_23595779 0.62 ENSDART00000134860
ENSDART00000138852
lcorl
ligand dependent nuclear receptor corepressor-like
chr6_+_52212927 0.62 ENSDART00000143458
ywhaba
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr4_+_73051901 0.61 ENSDART00000174219
zgc:152938
zgc:152938
chr15_-_41689684 0.61 ENSDART00000143447
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr18_+_6857071 0.61 ENSDART00000018735
ENSDART00000181969
dnaja2l
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr3_+_56574623 0.60 ENSDART00000130877
rac1b
Rac family small GTPase 1b
chr10_+_15603082 0.59 ENSDART00000024450
zfand5b
zinc finger, AN1-type domain 5b
chr2_-_19354622 0.57 ENSDART00000168627
zfyve9a
zinc finger, FYVE domain containing 9a
chr6_+_52212574 0.56 ENSDART00000025940
ywhaba
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr4_+_1722899 0.56 ENSDART00000021139
fgfr1op2
FGFR1 oncogene partner 2
chr23_-_27506161 0.55 ENSDART00000145007
asb8
ankyrin repeat and SOCS box containing 8
chr16_+_26732086 0.55 ENSDART00000138496
rad54b
RAD54 homolog B (S. cerevisiae)
chr8_+_48965767 0.55 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr17_-_8673567 0.54 ENSDART00000192714
ENSDART00000012546
ctbp2a
C-terminal binding protein 2a
chr23_-_10723009 0.53 ENSDART00000189721
foxp1a
forkhead box P1a
chr13_-_38792061 0.53 ENSDART00000162858
lmbrd1
LMBR1 domain containing 1
chr17_-_8674208 0.53 ENSDART00000149201
ctbp2a
C-terminal binding protein 2a
chr19_+_46222428 0.52 ENSDART00000183984
vps28
vacuolar protein sorting 28 (yeast)
chr17_+_23554932 0.49 ENSDART00000135814
pank1a
pantothenate kinase 1a
chr16_+_25137483 0.48 ENSDART00000155666
znf576.1
zinc finger protein 576, tandem duplicate 1
chr13_-_17464362 0.47 ENSDART00000145499
lrmda
leucine rich melanocyte differentiation associated
chr15_-_1844048 0.47 ENSDART00000102410
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr19_+_42660158 0.47 ENSDART00000018328
fbxl2
F-box and leucine-rich repeat protein 2
chr18_+_6558338 0.46 ENSDART00000110892
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr20_+_16639848 0.43 ENSDART00000063944
ENSDART00000152359
tmem30ab
transmembrane protein 30Ab
chr1_-_23596391 0.43 ENSDART00000155184
lcorl
ligand dependent nuclear receptor corepressor-like
chr3_-_18373604 0.42 ENSDART00000148132
spag9a
sperm associated antigen 9a
chr18_+_6558146 0.41 ENSDART00000169401
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr23_+_34990693 0.40 ENSDART00000013449
CHST13
si:ch211-236h17.3
chr3_-_18373425 0.39 ENSDART00000178522
spag9a
sperm associated antigen 9a
chr22_-_29922872 0.39 ENSDART00000020249
dusp5
dual specificity phosphatase 5
chr11_+_4026229 0.38 ENSDART00000041417
camk1b
calcium/calmodulin-dependent protein kinase Ib
chr11_-_17782930 0.38 ENSDART00000080770
tmf1
TATA element modulatory factor 1
chr7_+_1534820 0.37 ENSDART00000192997
tox4b
TOX high mobility group box family member 4 b
chr19_-_32888758 0.36 ENSDART00000052080
laptm4b
lysosomal protein transmembrane 4 beta
chr3_+_40284598 0.36 ENSDART00000009411
bud31
BUD31 homolog (S. cerevisiae)
chr12_+_36109507 0.35 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr14_+_31493306 0.35 ENSDART00000138341
phf6
PHD finger protein 6
chr23_+_17509794 0.34 ENSDART00000148457
gid8b
GID complex subunit 8 homolog b (S. cerevisiae)
chr14_+_31493119 0.34 ENSDART00000006463
phf6
PHD finger protein 6
chr13_+_35856463 0.34 ENSDART00000171056
ENSDART00000017202
kcnk1b
potassium channel, subfamily K, member 1b
chr2_+_30103131 0.33 ENSDART00000185119
dnajb6a
DnaJ (Hsp40) homolog, subfamily B, member 6a
chr21_-_9782502 0.31 ENSDART00000158836
arhgap24
Rho GTPase activating protein 24
chr1_-_55166511 0.31 ENSDART00000150430
ENSDART00000035725
pane1
proliferation associated nuclear element
chr9_-_13963078 0.30 ENSDART00000193398
ENSDART00000061156
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr15_+_5116179 0.30 ENSDART00000101937
pgm2l1
phosphoglucomutase 2-like 1
chr11_+_769623 0.30 ENSDART00000172972
vgll4b
vestigial-like family member 4b
chr5_+_72145468 0.30 ENSDART00000148626
abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr15_+_23443665 0.29 ENSDART00000059369
phykpl
5-phosphohydroxy-L-lysine phospho-lyase
chr3_-_11624694 0.29 ENSDART00000127157
hlfa
hepatic leukemia factor a
chr14_-_38946808 0.28 ENSDART00000139293
gla
galactosidase, alpha
chr10_+_28306749 0.28 ENSDART00000142016
ptrh2
peptidyl-tRNA hydrolase 2
chr9_-_6501924 0.28 ENSDART00000168143
nck2a
NCK adaptor protein 2a
chr13_+_18507592 0.27 ENSDART00000142622
si:ch211-198a12.6
si:ch211-198a12.6
chr5_+_36439405 0.25 ENSDART00000102973
eda
ectodysplasin A
chr17_+_8754020 0.24 ENSDART00000105322
edrf1
erythroid differentiation regulatory factor 1
chr4_-_1839192 0.24 ENSDART00000003790
pwp1
PWP1 homolog (S. cerevisiae)
chr8_+_23147218 0.23 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr10_-_41906609 0.23 ENSDART00000102530
kdm2bb
lysine (K)-specific demethylase 2Bb
chr25_+_18711804 0.21 ENSDART00000011149
fam185a
family with sequence similarity 185, member A
chr14_-_31619408 0.20 ENSDART00000173277
mmgt1
membrane magnesium transporter 1
chr3_-_40284744 0.20 ENSDART00000018626
pdap1b
pdgfa associated protein 1b
chr14_-_52433292 0.19 ENSDART00000164272
rest
RE1-silencing transcription factor
chr4_-_2945306 0.19 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr8_+_23147609 0.17 ENSDART00000180284
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr25_-_13659249 0.17 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr4_-_1839352 0.15 ENSDART00000189215
pwp1
PWP1 homolog (S. cerevisiae)
chr21_+_43171013 0.14 ENSDART00000151362
zcchc10
zinc finger, CCHC domain containing 10
chr10_-_2971407 0.13 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr22_-_4760187 0.13 ENSDART00000081969
rad23ab
RAD23 homolog A, nucleotide excision repair protein b
chr15_-_163586 0.13 ENSDART00000163597
SEPT4
septin-4
chr17_+_8184649 0.12 ENSDART00000091818
tulp4b
tubby like protein 4b
chr3_+_36713477 0.12 ENSDART00000181105
ENSDART00000161897
ENSDART00000189952
abcc1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr10_+_44940693 0.12 ENSDART00000157515
cnnm4a
cyclin and CBS domain divalent metal cation transport mediator 4a
chr10_+_14488625 0.12 ENSDART00000026383
sigmar1
sigma non-opioid intracellular receptor 1
chr8_-_24113575 0.11 ENSDART00000099692
ENSDART00000186211
dclre1b
DNA cross-link repair 1B
chr4_-_26035770 0.11 ENSDART00000124514
usp44
ubiquitin specific peptidase 44
chr9_-_42418470 0.10 ENSDART00000144353
calcrla
calcitonin receptor-like a
chr7_-_12909352 0.10 ENSDART00000172901
sh3gl3a
SH3-domain GRB2-like 3a
chr5_+_24128908 0.08 ENSDART00000029719
si:ch211-114c12.2
si:ch211-114c12.2
chr17_-_32621103 0.08 ENSDART00000155321
xkr5b
XK related 5b
chr12_-_30760971 0.08 ENSDART00000066257
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr17_-_31212420 0.07 ENSDART00000086511
rpusd2
RNA pseudouridylate synthase domain containing 2
chr10_-_9089545 0.04 ENSDART00000080781
arl15b
ADP-ribosylation factor-like 15b
chr17_-_2690083 0.03 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr18_-_5598958 0.02 ENSDART00000161538
cyp1a
cytochrome P450, family 1, subfamily A

Network of associatons between targets according to the STRING database.

First level regulatory network of e4f1+si:dkeyp-79b7.12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.4 1.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.3 1.6 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.3 1.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.3 0.8 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.7 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.2 0.9 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.2 0.8 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 0.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 3.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 1.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.7 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.1 0.8 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.7 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.6 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.1 1.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.2 GO:1903430 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.1 0.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 1.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.3 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 1.3 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.6 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 2.5 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 1.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.7 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 2.8 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.1 GO:0031627 telomeric loop formation(GO:0031627)
0.0 1.5 GO:0055088 lipid homeostasis(GO:0055088)
0.0 1.2 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 1.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.5 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 1.2 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.0 0.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 3.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 1.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3 1.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 0.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.9 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 1.5 GO:0046625 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.2 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.9 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 1.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.3 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.5 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 3.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 2.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.6 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 1.0 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.9 GO:0043130 ubiquitin binding(GO:0043130)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 3.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis