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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

Z-value: 0.52

Motif logo

Transcription factors associated with dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

Gene Symbol Gene ID Gene Info
ENSDARG00000017174 distal-less homeobox 2b
ENSDARG00000079964 distal-less homeobox 2a
ENSDARG00000116017 distal-less homeobox 2b
ENSDARG00000011956 distal-less homeobox 4a
ENSDARG00000042291 distal-less homeobox 6a
ENSDARG00000071560 distal-less homeobox 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx2adr11_v1_chr9_-_3400727_3400729-0.822.6e-05Click!
dlx2bdr11_v1_chr1_-_30979707_30979707-0.781.2e-04Click!
dlx4adr11_v1_chr3_+_34670076_34670076-0.711.0e-03Click!
dlx6adr11_v1_chr19_+_41464870_41464870-0.608.3e-03Click!
dlx4bdr11_v1_chr12_-_5728755_5728755-0.243.3e-01Click!

Activity profile of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a motif

Sorted Z-values of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 2.84 ENSDART00000021620
claudin d
chr11_-_6452444 2.70 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
La ribonucleoprotein domain family, member 6b
chr10_-_21362071 2.28 ENSDART00000125167
avidin
chr10_-_21362320 2.13 ENSDART00000189789
avidin
chr8_+_45334255 1.90 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr3_-_32337653 1.46 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr17_-_30635298 1.44 ENSDART00000155478
SH3 and SYLF domain containing 1
chr2_+_41526904 1.32 ENSDART00000127520
activin A receptor, type 1 like
chr17_+_16046132 1.29 ENSDART00000155005
si:ch73-204p21.2
chr17_+_16046314 1.28 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr20_-_23426339 1.27 ENSDART00000004625
zygote arrest 1
chr15_-_26931541 1.26 ENSDART00000027563
coiled-coil domain containing 9
chr8_-_20230559 1.24 ENSDART00000193677
MLLT1, super elongation complex subunit a
chr21_+_34088110 1.15 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
myotubularin related protein 1b
chr8_-_20230802 1.13 ENSDART00000063400
MLLT1, super elongation complex subunit a
chr8_-_19467011 1.12 ENSDART00000162010
zgc:92140
chr2_-_15324837 1.11 ENSDART00000015655
trans-2,3-enoyl-CoA reductase-like 2b
chr1_-_6028876 1.06 ENSDART00000168117
si:ch1073-345a8.1
chr8_+_11425048 1.02 ENSDART00000018739
tight junction protein 2b (zona occludens 2)
chr21_+_34088377 0.86 ENSDART00000170070
myotubularin related protein 1b
chr11_-_44801968 0.86 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr20_-_28800999 0.85 ENSDART00000049462
RAB15, member RAS oncogene family
chr18_-_40708537 0.82 ENSDART00000077577
si:ch211-132b12.8
chr1_-_43905252 0.81 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr6_+_50393047 0.79 ENSDART00000055502
ENSDART00000055511
ERGIC and golgi 3
chr16_-_17197546 0.78 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
glyceraldehyde-3-phosphate dehydrogenase
chr8_-_25034411 0.77 ENSDART00000135973
nuclear transcription factor Y, alpha, like
chr14_+_34490445 0.75 ENSDART00000132193
ENSDART00000148044
wingless-type MMTV integration site family, member 8a
chr17_+_26722904 0.75 ENSDART00000114927
NRDE-2, necessary for RNA interference, domain containing
chr16_-_17347727 0.70 ENSDART00000144392
zyxin
chr13_+_38817871 0.64 ENSDART00000187708
collagen, type XIX, alpha 1
chr3_-_26805455 0.63 ENSDART00000180648
phosphatidylinositol glycan anchor biosynthesis, class Q
chr20_+_27712714 0.62 ENSDART00000008306
zinc finger and BTB domain containing 1
chr3_+_28860283 0.61 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr9_-_35633827 0.60 ENSDART00000077745
zona pellucida glycoprotein 2, like 1
chr15_-_43284021 0.58 ENSDART00000041677
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr25_+_29662411 0.57 ENSDART00000077445
Pim-3 proto-oncogene, serine/threonine kinase
chr7_+_27603211 0.57 ENSDART00000148782
cytochrome P450, family 2, subfamily R, polypeptide 1
chr17_-_21162821 0.56 ENSDART00000157283
abhydrolase domain containing 12
chr19_-_7358184 0.54 ENSDART00000092379
oxidation resistance 1b
chr6_-_40922971 0.54 ENSDART00000155363
SFI1 centrin binding protein
chr8_-_39822917 0.52 ENSDART00000067843
zgc:162025
chr23_+_33963619 0.52 ENSDART00000140666
ENSDART00000084792
pyridoxal phosphate binding protein
chr7_-_48263516 0.52 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr2_-_7246848 0.51 ENSDART00000146434
zgc:153115
chr19_+_28187480 0.48 ENSDART00000183825
iroquois homeobox 4b
chr20_+_41021054 0.47 ENSDART00000146052
mannosidase, alpha, class 1A, member 1
chr11_+_31864921 0.47 ENSDART00000180252
diaphanous-related formin 3
chr12_+_22580579 0.46 ENSDART00000171725
ENSDART00000192290
capping protein (actin filament), gelsolin-like b
chr10_+_43039947 0.43 ENSDART00000193434
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr19_-_12212692 0.43 ENSDART00000142077
ENSDART00000151599
ENSDART00000140834
ENSDART00000078781
zinc finger protein 706
chr6_-_37744430 0.43 ENSDART00000150177
ENSDART00000149722
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr23_-_17484555 0.43 ENSDART00000187181
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr2_+_44972720 0.40 ENSDART00000075146
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr25_+_10410620 0.40 ENSDART00000151886
ets homologous factor
chr5_+_19314574 0.40 ENSDART00000133247
RUN and SH3 domain containing 2
chr21_-_3853204 0.40 ENSDART00000188829
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr23_+_38957472 0.39 ENSDART00000193836
ATPase phospholipid transporting 9A (putative)
chr24_-_34680956 0.39 ENSDART00000171009
catenin (cadherin-associated protein), alpha 1
chr16_-_13623659 0.39 ENSDART00000168978
si:dkeyp-69b9.6
chr14_-_33945692 0.38 ENSDART00000168546
ENSDART00000189778
zinc finger, DHHC-type containing 24
chr16_+_20161805 0.38 ENSDART00000192146
chromosome 16 C2orf66 homolog
chr17_+_28628404 0.38 ENSDART00000032975
ENSDART00000143607
HEAT repeat containing 5a
chr23_-_31913069 0.37 ENSDART00000135526
mitochondrial fission regulator 2
chr22_+_29113796 0.37 ENSDART00000150264
phospholipase A2, group VI (cytosolic, calcium-independent)
chr5_-_23117078 0.37 ENSDART00000051529
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr6_-_43283122 0.36 ENSDART00000186022
FERM domain containing 4Ba
chr19_-_8768564 0.36 ENSDART00000170416
si:ch73-350k19.1
chr7_+_39418869 0.35 ENSDART00000169195

chr16_-_42965192 0.35 ENSDART00000113714
metaxin 1a
chr15_+_17345609 0.35 ENSDART00000111753
vacuole membrane protein 1
chr16_+_13818500 0.35 ENSDART00000135245
folliculin
chr13_+_2625150 0.34 ENSDART00000164177
phospholipid phosphatase 4
chr14_-_32631013 0.34 ENSDART00000176815
ATPase phospholipid transporting 11C
chr25_+_15997957 0.32 ENSDART00000140047
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr15_-_34408777 0.32 ENSDART00000139934
alkylglycerol monooxygenase
chr16_+_13818743 0.32 ENSDART00000090191
folliculin
chr11_+_45110865 0.31 ENSDART00000158188
meningioma expressed antigen 5 (hyaluronidase) like
chr23_-_4966821 0.31 ENSDART00000147122
ENSDART00000145760
nerve growth factor a (beta polypeptide)
chr12_-_33817114 0.29 ENSDART00000161265
twinkle mtDNA helicase
chr7_-_54679595 0.28 ENSDART00000165320
cyclin D1
chr13_-_25720876 0.28 ENSDART00000142404
ENSDART00000146487
si:dkey-192p21.6
chr12_+_48803098 0.28 ENSDART00000074768
peptidylprolyl isomerase Fb
chr12_-_33579873 0.28 ENSDART00000184661
tudor and KH domain containing
chr15_+_31344472 0.27 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
odorant receptor, family D, subfamily 107, member 1
chr10_-_10969596 0.27 ENSDART00000092011
exonuclease 3'-5' domain containing 3
chr20_-_45060241 0.26 ENSDART00000185227
kelch-like family member 29
chr19_-_19871211 0.26 ENSDART00000170980
even-skipped homeobox 1
chr6_+_40922572 0.25 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_+_45365098 0.25 ENSDART00000052746
ENSDART00000156555
ubiquitin-conjugating enzyme E2Ia
chr1_+_513986 0.25 ENSDART00000109083
ENSDART00000081945
thioredoxin-like 4B
chr8_+_28452738 0.24 ENSDART00000062706
transmembrane protein 189
chr10_-_13343831 0.23 ENSDART00000135941
interleukin 11 receptor, alpha
chr9_-_21460164 0.23 ENSDART00000133469
zinc finger, MYM-type 2
chr8_-_19051906 0.23 ENSDART00000089024
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr2_-_38206034 0.23 ENSDART00000144518
ENSDART00000137395
apoptotic chromatin condensation inducer 1a
chr10_-_10969444 0.23 ENSDART00000138041
exonuclease 3'-5' domain containing 3
chr10_-_18463934 0.23 ENSDART00000133116
ENSDART00000113422
si:dkey-28o19.1
chr16_+_33163858 0.23 ENSDART00000101943
Ras-related GTP binding Ca
chr16_-_13623928 0.22 ENSDART00000164344
si:dkeyp-69b9.6
chr18_-_3552414 0.22 ENSDART00000163762
ENSDART00000165434
ENSDART00000161197
ENSDART00000166841
ENSDART00000170260
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr24_-_26981848 0.22 ENSDART00000183198
stromal antigen 1b
chr13_+_45431660 0.21 ENSDART00000099950
SYF2 pre-mRNA-splicing factor
chr5_-_57311037 0.21 ENSDART00000149855
fer (fps/fes related) tyrosine kinase
chr13_-_36911118 0.21 ENSDART00000048739
tripartite motif containing 9
chr18_+_15644559 0.21 ENSDART00000061794
nuclear receptor subfamily 1, group H, member 4
chr9_+_20557793 0.21 ENSDART00000178434
mannosidase, alpha, class 1A, member 2
chr20_+_13403281 0.20 ENSDART00000045183
ENSDART00000127350
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr2_-_33645411 0.19 ENSDART00000114663
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr16_+_35661771 0.18 ENSDART00000161393
MAP7 domain containing 1a
chr6_-_14292307 0.18 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr12_+_33395748 0.18 ENSDART00000129458
fatty acid synthase
chr19_+_46158078 0.17 ENSDART00000183933
ENSDART00000164055
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr17_+_24687338 0.17 ENSDART00000135794
selenoprotein N
chr10_-_33297864 0.17 ENSDART00000163360
PR/SET domain 15
chr23_+_20518504 0.17 ENSDART00000114246
activity-dependent neuroprotector homeobox b
chr13_+_38430466 0.17 ENSDART00000132691
adhesion G protein-coupled receptor B3
chr1_-_8566567 0.17 ENSDART00000114613
pentatricopeptide repeat domain 1
chr4_+_26629368 0.17 ENSDART00000183575
IQ motif and Sec7 domain 3a
chr8_-_23612462 0.16 ENSDART00000025024
solute carrier family 38, member 5b
chr7_-_12464412 0.16 ENSDART00000178723
ADAMTS-like 3
chr20_-_40758410 0.15 ENSDART00000183031
connexin 34.5
chr7_+_34592526 0.15 ENSDART00000173959
formin homology 2 domain containing 1
chr2_+_37227011 0.15 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr15_+_40792667 0.15 ENSDART00000193186
ENSDART00000184559
FAT atypical cadherin 3a
chr11_+_35171406 0.14 ENSDART00000110839
MON1 secretory trafficking family member A
chr12_+_34953038 0.14 ENSDART00000187022
ENSDART00000123988
ENSDART00000027034
QKI, KH domain containing, RNA binding 2
chr22_-_7129631 0.13 ENSDART00000171359
acid-sensing (proton-gated) ion channel 1b
chr24_-_30862168 0.13 ENSDART00000168540
polypyrimidine tract binding protein 2a
chr21_-_11654422 0.13 ENSDART00000081614
ENSDART00000132699
calpastatin
chr8_+_50953776 0.13 ENSDART00000013870
zgc:56596
chr8_-_46894362 0.12 ENSDART00000111124
acyl-CoA thioesterase 7
chr15_+_31806303 0.12 ENSDART00000155902
furry homolog a (Drosophila)
chr9_+_34331368 0.12 ENSDART00000147913
POU class 2 homeobox 1b
chr18_+_3064237 0.12 ENSDART00000161848
integrator complex subunit 4
chr25_-_27621268 0.12 ENSDART00000146205
ENSDART00000073511
hyaluronoglucosaminidase 6
chr1_+_52392511 0.11 ENSDART00000144025
si:ch211-217k17.8
chr9_+_17983463 0.11 ENSDART00000182150
A kinase (PRKA) anchor protein 11
chr25_+_7299488 0.11 ENSDART00000184836
high mobility group 20A
chr18_+_9362455 0.11 ENSDART00000187025
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr8_+_7801060 0.11 ENSDART00000161618
transcription factor binding to IGHM enhancer 3a
chr17_-_44247707 0.10 ENSDART00000126097
orthodenticle homeobox 2b
chr23_-_31913231 0.10 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr22_-_20386982 0.10 ENSDART00000089015
zinc finger and BTB domain containing 7a
chr18_+_9637744 0.09 ENSDART00000190171
piccolo presynaptic cytomatrix protein b
chr24_+_26134209 0.09 ENSDART00000038824
teleost multiple tissue opsin b
chr15_+_9053059 0.09 ENSDART00000012039
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr9_+_22485343 0.09 ENSDART00000146028
diacylglycerol kinase, gamma
chr6_-_44044385 0.09 ENSDART00000075497
RING1 and YY1 binding protein b
chr6_+_52880292 0.09 ENSDART00000077848
odorant receptor, family H, subfamily 137, member 4
chr18_-_33979422 0.09 ENSDART00000136535
ENSDART00000167698
si:ch211-203b20.7
chr24_-_30843250 0.09 ENSDART00000162920
polypyrimidine tract binding protein 2a
chr18_+_1837668 0.08 ENSDART00000164210

chr19_+_2631565 0.08 ENSDART00000171487
family with sequence similarity 126, member A
chr6_+_36807861 0.08 ENSDART00000161708
si:ch73-29l19.1
chr15_-_6247775 0.08 ENSDART00000148350
Down syndrome cell adhesion molecule b
chr23_+_20563779 0.07 ENSDART00000146008
CaM kinase-like vesicle-associated, like
chr16_+_35661331 0.07 ENSDART00000161725
MAP7 domain containing 1a
chr3_+_33440615 0.07 ENSDART00000146005
GTP binding protein 1
chr11_-_8126223 0.07 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr22_+_18315490 0.07 ENSDART00000160413
GATA zinc finger domain containing 2Ab
chr8_-_28259766 0.07 ENSDART00000134226
ENSDART00000087037
ENSDART00000136973
DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
chr15_-_25518084 0.06 ENSDART00000158594
hypoxia-inducible factor 1, alpha subunit, like
chr7_+_69019851 0.06 ENSDART00000162891

chr14_-_3381303 0.06 ENSDART00000171601
im:7150988
chr22_+_16308450 0.06 ENSDART00000105678
leucine rich repeat containing 39
chr20_+_13783040 0.06 ENSDART00000115329
ENSDART00000152497
lysophosphatidylglycerol acyltransferase 1
chr12_-_8504278 0.06 ENSDART00000135865
early growth response 2b
chr19_-_44955710 0.05 ENSDART00000165246
si:ch211-233f16.1
chr14_-_41075262 0.05 ENSDART00000180518
dystrophin related protein 2
chr21_+_28958471 0.05 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_+_16397063 0.05 ENSDART00000159794
mitochondrial calcium uptake family, member 3a
chr19_-_38830582 0.05 ENSDART00000189966
ENSDART00000183055
adhesion G protein-coupled receptor B2
chr22_-_20166660 0.05 ENSDART00000085913
ENSDART00000188241
BTB (POZ) domain containing 2a
chr19_-_19556778 0.05 ENSDART00000164060
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr23_-_38497705 0.04 ENSDART00000109493
teashirt zinc finger homeobox 2
chr5_+_20147830 0.04 ENSDART00000098727
SV2 related protein a
chr13_+_25720969 0.04 ENSDART00000046050
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr4_-_46915962 0.04 ENSDART00000169555
si:ch211-134c10.1
chr19_-_19379084 0.04 ENSDART00000165206
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr22_+_31295791 0.04 ENSDART00000092447
glutamate receptor interacting protein 2b
chr22_+_16308806 0.04 ENSDART00000162685
leucine rich repeat containing 39
chr19_-_20403845 0.04 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
deleted in azoospermia-like
chr23_+_17387325 0.04 ENSDART00000083947
PTK6 protein tyrosine kinase 6b
chr2_+_33326522 0.03 ENSDART00000056655
Kruppel-like factor 17
chr13_-_40141630 0.03 ENSDART00000181618
ENSDART00000171583
ENSDART00000192780
cartilage acidic protein 1b
chr20_-_38617766 0.03 ENSDART00000050474
solute carrier family 30 (zinc transporter), member 2
chr7_-_44957503 0.03 ENSDART00000165077
cadherin 16, KSP-cadherin
chr6_-_46782176 0.03 ENSDART00000185559
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 4
chr1_+_16396870 0.03 ENSDART00000189245
ENSDART00000113266
mitochondrial calcium uptake family, member 3a
chr18_+_34478959 0.03 ENSDART00000059394
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr1_+_8534698 0.03 ENSDART00000021504
Smith-Magenis syndrome chromosome region, candidate 8b
chr1_-_49947482 0.03 ENSDART00000143398
sphingomyelin synthase 2
chr1_-_49947290 0.03 ENSDART00000141476
sphingomyelin synthase 2
chr5_+_37032038 0.03 ENSDART00000045036
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr1_+_56755536 0.03 ENSDART00000157727

chr10_+_40660772 0.02 ENSDART00000148007
trace amine associated receptor 19l
chr17_+_23298928 0.02 ENSDART00000153652
zgc:165461
chr5_+_38837429 0.02 ENSDART00000160236
Fraser extracellular matrix complex subunit 1
chr21_-_10488379 0.02 ENSDART00000163878
hyperpolarization activated cyclic nucleotide-gated potassium channel 1

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 1.3 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.3 0.8 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 0.5 GO:0097065 anterior head development(GO:0097065)
0.1 0.6 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.7 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.5 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.7 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.6 GO:0070640 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 1.5 GO:0006825 copper ion transport(GO:0006825)
0.1 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.0 0.2 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 1.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 1.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.2 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 1.2 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.1 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.4 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 1.5 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.2 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.5 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:0048785 hatching gland development(GO:0048785)
0.0 0.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.9 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0070724 BMP receptor complex(GO:0070724)
0.3 0.8 GO:0097189 apoptotic body(GO:0097189)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.5 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 4.2 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0001726 ruffle(GO:0001726)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0009374 biotin binding(GO:0009374)
0.3 1.5 GO:0016531 copper chaperone activity(GO:0016531)
0.2 2.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 0.8 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.4 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 1.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.7 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 3.0 GO:0042802 identical protein binding(GO:0042802)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG