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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for dbpa+dbpb+hlfa

Z-value: 0.73

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Transcription factors associated with dbpa+dbpb+hlfa

Gene Symbol Gene ID Gene Info
ENSDARG00000057652 D site albumin promoter binding protein b
ENSDARG00000063014 D site albumin promoter binding protein a
ENSDARG00000074752 HLF transcription factor, PAR bZIP family member a
ENSDARG00000116703 D site albumin promoter binding protein b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dbpbdr11_v1_chr16_-_13612650_136126500.807.2e-05Click!
dbpadr11_v1_chr19_-_10196370_101963700.644.2e-03Click!
hlfadr11_v1_chr3_-_11624694_11624694-0.428.4e-02Click!

Activity profile of dbpa+dbpb+hlfa motif

Sorted Z-values of dbpa+dbpb+hlfa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_33361425 2.43 ENSDART00000031638
solute carrier family 48 (heme transporter), member 1a
chr16_+_34523515 1.35 ENSDART00000041007
stathmin 1b
chr15_+_34988148 1.19 ENSDART00000076269
coiled-coil domain containing 105
chr10_+_506538 1.19 ENSDART00000141713
si:ch211-242f23.3
chr9_-_1702648 1.13 ENSDART00000102934
heterogeneous nuclear ribonucleoprotein A3
chr20_+_1121458 1.12 ENSDART00000064472
proline-rich nuclear receptor coactivator 1
chr9_-_9225980 1.00 ENSDART00000180301
cystathionine-beta-synthase b
chr18_+_26899316 0.99 ENSDART00000050230
tetraspanin 3a
chr6_+_37754763 0.96 ENSDART00000110770
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr9_-_48736388 0.91 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr14_-_12071679 0.83 ENSDART00000165581
thymosin beta 1
chr5_-_69212184 0.79 ENSDART00000053963
methionine adenosyltransferase II, alpha b
chr22_+_10606573 0.78 ENSDART00000192638
RAD54 like 2
chr15_-_20939579 0.78 ENSDART00000152371
ubiquitin specific peptidase 2a
chr4_-_12914163 0.76 ENSDART00000140002
ENSDART00000145917
ENSDART00000141355
ENSDART00000067135
methionine sulfoxide reductase B3
chr17_-_8268406 0.74 ENSDART00000149873
ENSDART00000064668
ENSDART00000148403
Abelson helper integration site 1
chr19_+_46259619 0.71 ENSDART00000158032
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr16_+_23397785 0.69 ENSDART00000148961
S100 calcium binding protein A10b
chr21_-_32467799 0.69 ENSDART00000007675
ENSDART00000133099
zgc:123105
chr8_+_12930216 0.64 ENSDART00000115405
zgc:103670
chr25_+_34014523 0.61 ENSDART00000182856
annexin A2a
chr22_+_10606863 0.59 ENSDART00000147975
RAD54 like 2
chr11_+_39135050 0.59 ENSDART00000180571
ENSDART00000189685
cell division cycle 42
chr15_-_29348212 0.58 ENSDART00000133117
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr21_+_43178831 0.57 ENSDART00000151512
AF4/FMR2 family, member 4
chr5_+_69808763 0.56 ENSDART00000143482
fibronectin type III and SPRY domain containing 1-like
chr12_-_20373058 0.54 ENSDART00000066382
aquaporin 8a, tandem duplicate 1
chr16_+_23398369 0.54 ENSDART00000037694
S100 calcium binding protein A10b
chr6_+_44197099 0.50 ENSDART00000124168
protein phosphatase 4, regulatory subunit 2b
chr19_+_9032073 0.50 ENSDART00000127755
ash1 (absent, small, or homeotic)-like (Drosophila)
chr14_+_4151379 0.49 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr6_+_44197348 0.48 ENSDART00000075486
protein phosphatase 4, regulatory subunit 2b
chr8_+_247163 0.48 ENSDART00000122378
centrosomal protein 120
chr18_-_39288894 0.48 ENSDART00000186216
mitogen-activated protein kinase 6
chr8_-_53044300 0.47 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr6_-_41085692 0.45 ENSDART00000181463
serine/arginine-rich splicing factor 3a
chr5_-_36949476 0.45 ENSDART00000047269
H3 histone, family 3C
chr23_+_9522781 0.44 ENSDART00000136486
oxysterol binding protein-like 2b
chr21_-_32467099 0.43 ENSDART00000186354
zgc:123105
chr8_-_41228530 0.43 ENSDART00000165949
ENSDART00000173055
fumarylacetoacetate hydrolase domain containing 2A
chr8_-_11324143 0.42 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr7_+_67733759 0.41 ENSDART00000172015
cytochrome b5 type B
chr22_+_17531214 0.40 ENSDART00000161174
ENSDART00000088356
heterogeneous nuclear ribonucleoprotein M
chr24_-_39772045 0.39 ENSDART00000087441
si:ch211-276f18.2
chr4_+_5341592 0.37 ENSDART00000123375
ENSDART00000067371
zgc:113263
chr5_+_22974019 0.37 ENSDART00000147157
ENSDART00000020434
bromodomain and WD repeat domain containing 3
chr23_-_18981595 0.37 ENSDART00000147617
bcl2-like 1
chr16_-_33105677 0.36 ENSDART00000145055
proline-rich nuclear receptor coactivator 2
chr8_-_31716302 0.36 ENSDART00000061832
si:dkey-46a10.3
chr1_-_59411901 0.36 ENSDART00000167015
si:ch211-188p14.4
chr5_-_15494164 0.35 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
TAO kinase 3a
chr6_+_48348415 0.35 ENSDART00000064826
Mov10 RISC complex RNA helicase a
chr23_+_33963619 0.35 ENSDART00000140666
ENSDART00000084792
pyridoxal phosphate binding protein
chr24_+_14581864 0.35 ENSDART00000134536
thiamine triphosphatase
chr1_-_35928942 0.32 ENSDART00000033566
SMAD family member 1
chr10_+_18911152 0.32 ENSDART00000030205
BCL2 interacting protein 3 like b
chr22_-_881725 0.32 ENSDART00000035514
choline/ethanolamine phosphotransferase 1b
chr13_-_293250 0.31 ENSDART00000138581
chitin synthase 1
chr9_+_1654284 0.31 ENSDART00000062854
nuclear factor, erythroid 2-like 2a
chr16_+_5408748 0.31 ENSDART00000160008
ENSDART00000014024
plectin b
chr12_-_26383242 0.29 ENSDART00000152941
ubiquitin specific peptidase 54b
chr7_+_38278860 0.29 ENSDART00000016265
low density lipoprotein receptor-related protein 3
chr12_-_23365737 0.29 ENSDART00000170376
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr8_-_53044089 0.29 ENSDART00000135982
nuclear receptor subfamily 6, group A, member 1a
chr19_+_4990320 0.28 ENSDART00000147056
zgc:91968
chr18_-_15551360 0.28 ENSDART00000159915
ENSDART00000172690
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr17_-_17759138 0.28 ENSDART00000157128
ENSDART00000123845
aarF domain containing kinase 1
chr24_-_21343982 0.27 ENSDART00000012653
spindle and centriole associated protein 1
chr12_-_5120175 0.27 ENSDART00000160729
retinol binding protein 4, plasma
chr7_+_38380135 0.27 ENSDART00000174005
rhophilin, Rho GTPase binding protein 2
chr22_+_15973122 0.26 ENSDART00000144545
ring finger and CCCH-type domains 1a
chr16_-_45069882 0.26 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr6_+_23810529 0.26 ENSDART00000166921
glutamate-ammonia ligase (glutamine synthase) b
chr7_-_7823662 0.26 ENSDART00000167652
chemokine (C-X-C motif) ligand 8b, duplicate 3
chr15_+_32711663 0.25 ENSDART00000157854
ENSDART00000167515
periostin, osteoblast specific factor b
chr6_+_23809163 0.25 ENSDART00000170402
glutamate-ammonia ligase (glutamine synthase) b
chr17_-_20979077 0.25 ENSDART00000006676
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr19_+_342094 0.25 ENSDART00000151013
ENSDART00000187622
endosulfine alpha a
chr15_+_26600611 0.25 ENSDART00000155352
solute carrier family 47 (multidrug and toxin extrusion), member 3
chr1_-_35929143 0.25 ENSDART00000185002
SMAD family member 1
chr17_+_43013171 0.24 ENSDART00000055541
gsk3b interacting protein
chr25_-_12803723 0.24 ENSDART00000158787
carbonic anhydrase Va
chr7_+_69528850 0.24 ENSDART00000109507
Rap1 GTPase-GDP dissociation stimulator 1
chr15_+_21882419 0.23 ENSDART00000157216
si:dkey-103g5.4
chr23_+_16814968 0.23 ENSDART00000161299
zgc:100832
chr3_-_32927516 0.23 ENSDART00000140117
amine oxidase, copper containing 2
chr17_+_25833947 0.22 ENSDART00000044328
ENSDART00000154604
acyl-CoA synthetase short chain family member 1
chr20_-_33675676 0.22 ENSDART00000147168
rho-associated, coiled-coil containing protein kinase 2b
chr6_+_9130989 0.22 ENSDART00000162588
regucalcin
chr13_+_30035253 0.22 ENSDART00000181303
ENSDART00000057525
ENSDART00000136622
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr10_-_24371312 0.21 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr20_-_45661049 0.21 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr3_-_28665291 0.21 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr1_-_10071422 0.21 ENSDART00000135522
ENSDART00000033118
fibrinogen alpha chain
chr22_-_13165186 0.21 ENSDART00000105762
aryl hydrocarbon receptor 2
chr4_+_21867522 0.20 ENSDART00000140400
acyl-CoA synthetase short chain family member 3
chr2_+_10134345 0.20 ENSDART00000100725
alpha-2-HS-glycoprotein 2
chr6_+_41255485 0.20 ENSDART00000042683
ENSDART00000186013
Ca2+-dependent activator protein for secretion b
chr3_-_21348478 0.20 ENSDART00000114906
family with sequence similarity 171, member A2a
chr25_-_1235457 0.20 ENSDART00000093093
coronin, actin binding protein, 2Bb
chr4_-_12725513 0.20 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr5_+_26121393 0.19 ENSDART00000002221
beta-carotene 15, 15-dioxygenase 2, like
chr6_-_14292307 0.19 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr11_-_10770053 0.19 ENSDART00000179213
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr17_-_52091999 0.19 ENSDART00000019766
transforming growth factor, beta 3
chr6_+_23809501 0.19 ENSDART00000168701
glutamate-ammonia ligase (glutamine synthase) b
chr10_-_25591194 0.18 ENSDART00000131640
T cell lymphoma invasion and metastasis 1a
chr25_+_28893615 0.18 ENSDART00000156994
ENSDART00000075151
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr8_+_7801060 0.18 ENSDART00000161618
transcription factor binding to IGHM enhancer 3a
chr14_+_21699129 0.18 ENSDART00000073707
syntaxin 3A
chr9_-_9732212 0.18 ENSDART00000092884
leucine rich repeat containing 58b
chr20_-_20610812 0.17 ENSDART00000181870
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr14_+_7377552 0.17 ENSDART00000142158
ENSDART00000141471
histidyl-tRNA synthetase
chr22_+_20720808 0.17 ENSDART00000171321
si:dkey-211f22.5
chr3_-_336299 0.17 ENSDART00000105021
major histocompatibility complex class I ZFA
chr18_+_507618 0.17 ENSDART00000159464
neural precursor cell expressed, developmentally down-regulated 4a
chr6_+_16468776 0.17 ENSDART00000109151
ENSDART00000114667
zgc:161969
chr16_-_35427060 0.17 ENSDART00000172294
CTP synthase 1b
chr17_+_24036791 0.17 ENSDART00000140767
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr11_-_40147032 0.17 ENSDART00000052918
si:dkey-264d12.4
chr8_+_17884569 0.17 ENSDART00000134660
solute carrier family 44, member 5b
chr6_-_7726849 0.16 ENSDART00000151511
solute carrier family 25, member 38b
chr23_+_33947874 0.16 ENSDART00000136104
si:ch211-148l7.4
chr6_+_10333920 0.16 ENSDART00000151667
ENSDART00000151477
cordon-bleu WH2 repeat protein-like 1a
chr8_-_29851706 0.16 ENSDART00000149297
solute carrier family 20 (phosphate transporter), member 2
chr9_-_35069645 0.15 ENSDART00000122679
ENSDART00000077908
ENSDART00000077894
ENSDART00000125536
amyloid beta (A4) precursor protein b
chr16_+_40954481 0.15 ENSDART00000058587
glycogen synthase kinase binding protein
chr3_-_36209936 0.15 ENSDART00000175208
casein kinase 1, delta a
chr5_-_29488245 0.15 ENSDART00000047719
ENSDART00000141154
ENSDART00000171165
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
chr21_-_39058490 0.15 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr12_-_22400999 0.15 ENSDART00000153194
si:dkey-38p12.3
chr11_-_45138857 0.14 ENSDART00000166501
calcium activated nucleotidase 1b
chr25_-_2081371 0.14 ENSDART00000104915
ENSDART00000156925
wingless-type MMTV integration site family, member 7Bb
chr3_-_31804481 0.14 ENSDART00000028270
glial fibrillary acidic protein
chr18_+_24562188 0.14 ENSDART00000099463
LysM, putative peptidoglycan-binding, domain containing 4
chr7_+_52761841 0.14 ENSDART00000111444
diphosphoinositol pentakisphosphate kinase 1a
chr14_-_30905288 0.14 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
chr21_-_39566854 0.13 ENSDART00000020174
dynein, light chain, LC8-type 2b
chr14_+_21699414 0.13 ENSDART00000169942
syntaxin 3A
chr25_+_24616717 0.13 ENSDART00000089113
ankyrin repeat and BTB (POZ) domain containing 2b
chr7_+_19835569 0.13 ENSDART00000149812
ovo-like zinc finger 1a
chr19_+_7735157 0.13 ENSDART00000186717
tuftelin 1b
chr25_+_15354095 0.13 ENSDART00000090397
KIAA1549-like a
chr5_+_27583117 0.13 ENSDART00000180340
zinc finger, matrin-type 4a
chr20_-_20611063 0.13 ENSDART00000063492
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr7_+_56577906 0.12 ENSDART00000184023
haptoglobin
chr23_-_29812667 0.12 ENSDART00000006120
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr7_-_41420226 0.12 ENSDART00000074155
ATP-binding cassette, sub-family F (GCN20), member 2b
chr15_-_22074315 0.12 ENSDART00000149830
dopamine receptor D2a
chr11_+_43419809 0.12 ENSDART00000172982
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr12_+_15002757 0.12 ENSDART00000135036
myosin light chain, phosphorylatable, fast skeletal muscle b
chr16_-_7828838 0.12 ENSDART00000191434
ENSDART00000108653
T cell activation inhibitor, mitochondrial
chr8_+_1187928 0.12 ENSDART00000127252
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr7_-_38792543 0.11 ENSDART00000157416
si:dkey-23n7.10
chr9_-_13871935 0.11 ENSDART00000146597
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr9_-_6927587 0.11 ENSDART00000059092
transmembrane protein 182a
chr12_-_9538578 0.10 ENSDART00000066445
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr2_-_51772438 0.10 ENSDART00000170241
Danio rerio three-finger protein 5 (LOC100003647), mRNA.
chr20_-_25533739 0.10 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr3_+_19687217 0.09 ENSDART00000141937
tousled-like kinase 2
chr14_+_16345003 0.09 ENSDART00000003040
ENSDART00000165193
intelectin 3
chr3_-_31875138 0.09 ENSDART00000155298
LIM domain containing 2
chr16_-_20294236 0.08 ENSDART00000059623
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr20_+_25563105 0.08 ENSDART00000063100
cytochrome P450, family 2, subfamily P, polypeptide 6
chr20_-_35246150 0.08 ENSDART00000090549
frizzled class receptor 3a
chr19_+_41080240 0.08 ENSDART00000087295
protein phosphatase 1, regulatory subunit 9A
chr12_+_8003872 0.08 ENSDART00000180300
ENSDART00000126661
Rho-related BTB domain containing 1
chr25_-_16826219 0.08 ENSDART00000191299
ENSDART00000188504
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr23_-_30960506 0.07 ENSDART00000142661
oxysterol binding protein-like 2a
chr20_-_40755614 0.07 ENSDART00000061247
connexin 32.3
chr9_+_32301456 0.07 ENSDART00000078608
ENSDART00000185153
ENSDART00000144947
heat shock 10 protein 1
chr4_+_21866851 0.07 ENSDART00000177640
acyl-CoA synthetase short chain family member 3
chr16_+_46111849 0.07 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr3_-_26184018 0.07 ENSDART00000191604
si:ch211-11k18.4
chr1_+_2128970 0.07 ENSDART00000180074
ENSDART00000022019
ENSDART00000098059
muscleblind-like splicing regulator 2
chr14_-_9199968 0.07 ENSDART00000146113
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr6_+_22025806 0.06 ENSDART00000151240
si:dkey-156n14.3
chr7_+_46020508 0.06 ENSDART00000170294
cyclin E1
chr6_-_40583253 0.06 ENSDART00000032603
translocator protein
chr13_+_23157053 0.06 ENSDART00000162359
sorbin and SH3 domain containing 1
chr20_-_1151265 0.06 ENSDART00000012376
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr2_+_49860722 0.06 ENSDART00000144060
ribosomal protein L37
chr1_+_31112436 0.05 ENSDART00000075340
eukaryotic translation elongation factor 1 alpha 1b
chr4_-_20181964 0.05 ENSDART00000022539
fibrinogen-like 2a
chr16_+_14029283 0.05 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr2_+_36616830 0.05 ENSDART00000169547
ENSDART00000098417
p21 protein (Cdc42/Rac)-activated kinase 2a
chr4_-_5302866 0.05 ENSDART00000138590
si:ch211-214j24.9
chr22_-_10121880 0.05 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr5_+_3501859 0.05 ENSDART00000080486
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr23_-_37291793 0.05 ENSDART00000083281
ENSDART00000187108
mitochondrial E3 ubiquitin protein ligase 1b
chr10_+_9595575 0.05 ENSDART00000091780
ENSDART00000184287
ring finger and CCCH-type domains 2
chr10_+_10210455 0.05 ENSDART00000144214
SH2 domain containing 3Ca
chr25_+_32473277 0.05 ENSDART00000146451
sulfide quinone oxidoreductase
chr22_+_15323930 0.05 ENSDART00000142416
si:dkey-236e20.3
chr11_+_43751263 0.05 ENSDART00000163843
zgc:153431
chr25_-_11088839 0.05 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr23_+_16815353 0.04 ENSDART00000142789
ENSDART00000143424
zgc:100832
chr24_+_18948665 0.04 ENSDART00000106186
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr1_-_45215343 0.04 ENSDART00000014727
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr21_-_20733615 0.04 ENSDART00000145544
si:ch211-22d5.2

Network of associatons between targets according to the STRING database.

First level regulatory network of dbpa+dbpb+hlfa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.2 2.4 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 0.8 GO:0030091 protein repair(GO:0030091)
0.1 0.6 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.5 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 0.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.2 GO:0042364 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.7 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.2 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.1 0.3 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.3 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.3 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 0.2 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.1 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.3 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 0.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.3 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0 0.3 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.4 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.2 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 0.1 GO:0070285 pigment cell development(GO:0070285)
0.0 0.3 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.3 GO:0016203 muscle attachment(GO:0016203)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.8 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.0 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.8 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 0.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0016586 RSC complex(GO:0016586)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0030428 cell septum(GO:0030428)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 2.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 0.0 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0015232 heme transporter activity(GO:0015232)
0.2 1.0 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.2 0.8 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.4 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 0.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.7 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.3 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.3 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.5 GO:0015250 water channel activity(GO:0015250)
0.1 0.3 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.6 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.3 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.1 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.0 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis