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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for ctcf

Z-value: 0.87

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Transcription factors associated with ctcf

Gene Symbol Gene ID Gene Info
ENSDARG00000056621 CCCTC-binding factor (zinc finger protein)
ENSDARG00000113285 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ctcfdr11_v1_chr18_+_22287084_222871880.233.5e-01Click!

Activity profile of ctcf motif

Sorted Z-values of ctcf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_28777557 2.48 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
chr22_-_28777374 2.32 ENSDART00000188206
si:dkeyp-34c12.1
chr21_-_19918286 2.27 ENSDART00000180816
protein phosphatase 1, regulatory subunit 3B
chr5_-_29514689 2.26 ENSDART00000126018
ENSDART00000125175
euchromatic histone-lysine N-methyltransferase 1a
chr14_-_41468892 2.14 ENSDART00000173099
ENSDART00000003170
MID1 interacting protein 1, like
chr23_-_43595956 1.81 ENSDART00000162186
itchy E3 ubiquitin protein ligase b
chr14_+_22129096 1.75 ENSDART00000132514
cyclin G1
chr12_+_31783066 1.68 ENSDART00000105584
leucine rich repeat containing 59
chr11_-_25257595 1.66 ENSDART00000123567
snail family zinc finger 1a
chr25_+_8921425 1.65 ENSDART00000128591
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr13_-_36761379 1.62 ENSDART00000131534
ENSDART00000029824
mitogen-activated protein kinase kinase kinase kinase 5
chr12_-_48374728 1.60 ENSDART00000153403
ENSDART00000188117
DnaJ (Hsp40) homolog, subfamily B, member 12b
chr25_+_5972690 1.57 ENSDART00000067517
si:ch211-11i22.4
chr6_+_60125033 1.47 ENSDART00000148557
ENSDART00000008224
aurora kinase A
chr9_-_34269066 1.46 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr6_-_42388608 1.45 ENSDART00000049425
Sec61 translocon alpha 1 subunit, like
chr1_+_45958904 1.45 ENSDART00000108528
Rho guanine nucleotide exchange factor (GEF) 7b
chr5_+_54497475 1.44 ENSDART00000158149
ENSDART00000163968
ENSDART00000160446
transmembrane protein 203
chr10_+_2842923 1.38 ENSDART00000181895
YKT6 v-SNARE homolog (S. cerevisiae)
chr12_-_10567188 1.35 ENSDART00000144283
myoferlin
chr1_+_58922027 1.34 ENSDART00000159479
thyroid hormone receptor interactor 10b
chr6_-_41028698 1.34 ENSDART00000134293
TruB pseudouridine (psi) synthase family member 2
chr13_-_35765028 1.33 ENSDART00000157391
endoplasmic reticulum lectin 1
chr10_+_41939963 1.32 ENSDART00000126248
transmembrane protein 120B
chr23_+_24501918 1.31 ENSDART00000078824
SUZ RNA binding domain containing 1
chr19_+_24068223 1.30 ENSDART00000141351
ENSDART00000100420
peroxisomal biogenesis factor 11 beta
chr8_-_34427364 1.29 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
GTPase activating protein and VPS9 domains 1
chr6_+_48206535 1.27 ENSDART00000075172
CTTNBP2 N-terminal like a
chr1_+_40613297 1.26 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr12_-_3077395 1.26 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_+_41496490 1.25 ENSDART00000039369
Fanconi anemia, complementation group G
chr9_-_14273652 1.24 ENSDART00000135458
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr17_-_10498347 1.23 ENSDART00000171324
mirror-image polydactyly 1
chr9_-_30243393 1.22 ENSDART00000089539
si:dkey-100n23.3
chr18_-_40753583 1.18 ENSDART00000026767
v-akt murine thymoma viral oncogene homolog 2
chr1_+_26676758 1.18 ENSDART00000152299
si:dkey-25o16.4
chr9_-_11655031 1.16 ENSDART00000044314
integrin, alpha V
chr12_-_31726748 1.15 ENSDART00000153174
serine/arginine-rich splicing factor 2a
chr7_+_34236238 1.15 ENSDART00000052474
timeless interacting protein
chr1_+_2301961 1.15 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr7_+_66634167 1.13 ENSDART00000027616
eukaryotic translation initiation factor 4, gamma 2a
chr2_-_42492445 1.12 ENSDART00000139929
extended synaptotagmin-like protein 2a
chr16_-_32672883 1.11 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
PNN-interacting serine/arginine-rich protein
chr16_+_40340523 1.11 ENSDART00000102571
methyltransferase like 6
chr12_+_19976400 1.10 ENSDART00000153177
MKL/myocardin-like 2a
chr17_+_33158350 1.10 ENSDART00000104476
sorting nexin 9a
chr16_+_40340222 1.08 ENSDART00000190631
methyltransferase like 6
chr10_+_6340478 1.06 ENSDART00000163182
ENSDART00000163722
tropomyosin 2 (beta)
chr15_+_22435460 1.05 ENSDART00000031976
transmembrane protein 136a
chr11_-_2270069 1.05 ENSDART00000189005
zinc finger protein 740a
chr7_-_58251527 1.04 ENSDART00000114008
ENSDART00000185189
un-named hu7910
chr23_-_18057270 1.02 ENSDART00000173385
zgc:92287
chr16_-_8132742 1.01 ENSDART00000104323
SNF related kinase a
chr17_+_22577472 1.00 ENSDART00000045099
Yip1 domain family, member 4
chr1_+_49878000 1.00 ENSDART00000047876
lymphoid enhancer-binding factor 1
chr5_-_31773208 0.99 ENSDART00000137556
ENSDART00000122066
family with sequence similarity 102, member Ab
chr21_+_43702016 0.97 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr6_-_37749711 0.95 ENSDART00000078324
non imprinted in Prader-Willi/Angelman syndrome 1
chr22_-_718615 0.95 ENSDART00000149320
ADP-ribosylation factor-like 8A
chr1_-_24255149 0.95 ENSDART00000146960
LPS-responsive vesicle trafficking, beach and anchor containing
chr12_+_23991639 0.95 ENSDART00000003143
proteasome activator subunit 4b
chr12_+_23991276 0.95 ENSDART00000153136
proteasome activator subunit 4b
chr20_-_30931139 0.95 ENSDART00000006778
ENSDART00000146376
acetyl-CoA acetyltransferase 2
chr3_+_24050043 0.94 ENSDART00000151788
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr13_-_37600600 0.94 ENSDART00000003888
small nuclear RNA activating complex, polypeptide 1b
chr15_-_43978141 0.92 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr14_+_31473866 0.92 ENSDART00000173088
coiled-coil domain containing 160
chr5_-_1869982 0.90 ENSDART00000055878
RNA terminal phosphate cyclase-like 1
chr12_-_999762 0.89 ENSDART00000127003
ENSDART00000084076
ENSDART00000152425
methyltransferase like 9
chr6_-_1591002 0.88 ENSDART00000087039
zgc:123305
chr8_-_11324143 0.88 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr2_+_23701613 0.85 ENSDART00000047073
oxidative stress responsive 1a
chr3_-_37148594 0.84 ENSDART00000140855
MLX, MAX dimerization protein
chr16_-_24642814 0.84 ENSDART00000153987
ENSDART00000154319
FXYD domain containing ion transport regulator 6 like
chr1_+_21937201 0.83 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr22_-_20403194 0.83 ENSDART00000010048
mitogen-activated protein kinase kinase 2a
chr2_+_43204919 0.82 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr2_+_3823813 0.81 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
Niemann-Pick disease, type C1
chr21_+_25120546 0.81 ENSDART00000149507
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr8_+_26007988 0.81 ENSDART00000193948
ENSDART00000058100
xeroderma pigmentosum, complementation group C
chr21_-_21824285 0.80 ENSDART00000030984
WD repeat domain 73
chr8_+_42917515 0.79 ENSDART00000021715
solute carrier family 23 (ascorbic acid transporter), member 2
chr24_-_17400143 0.78 ENSDART00000134947
cullin 1b
chr6_+_21993613 0.78 ENSDART00000160750
ENSDART00000083070
THUMP domain containing 3
chr22_+_35131890 0.77 ENSDART00000003303
ENSDART00000130581
ring finger protein 13
chr3_+_36671585 0.76 ENSDART00000159033
nudE neurodevelopment protein 1
chr21_-_21514176 0.76 ENSDART00000031205
nectin cell adhesion molecule 3b
chr19_-_19871211 0.75 ENSDART00000170980
even-skipped homeobox 1
chr8_-_38317914 0.74 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr20_+_38458084 0.74 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr11_+_25157374 0.72 ENSDART00000019450
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr9_+_21148318 0.71 ENSDART00000035428
hydroxyacid oxidase 2 (long chain)
chr10_-_25716841 0.71 ENSDART00000140483
ENSDART00000125665
ENSDART00000181678
SR-related CTD-associated factor 4a
chr19_+_20785724 0.70 ENSDART00000038942
ADNP homeobox 2b
chr5_+_55934129 0.69 ENSDART00000050969
transmembrane protein 150Ab
chr17_+_31621788 0.69 ENSDART00000111629
ENSDART00000157148
cyclin-dependent kinase 2 interacting protein
chr9_-_11263228 0.69 ENSDART00000113847
chondroitin polymerizing factor a
chr17_-_51829310 0.67 ENSDART00000154544
numb homolog (Drosophila)
chr5_-_32396929 0.67 ENSDART00000023977
F-box and WD repeat domain containing 2
chr8_+_20488322 0.67 ENSDART00000036630
zgc:101100
chr14_+_7377552 0.65 ENSDART00000142158
ENSDART00000141471
histidyl-tRNA synthetase
chr2_-_40135942 0.65 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
eph receptor A4a
chr3_+_40407352 0.65 ENSDART00000155112
trinucleotide repeat containing 18
chr17_-_25303486 0.62 ENSDART00000162235
peptidylprolyl isomerase E (cyclophilin E)
chr3_+_31093455 0.62 ENSDART00000153074
si:dkey-66i24.9
chr13_+_35528607 0.61 ENSDART00000075414
ENSDART00000112947
WD repeat domain 27
chr1_+_218524 0.60 ENSDART00000109529
transmembrane and coiled-coil domains 3
chr8_+_13364950 0.60 ENSDART00000159760
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr5_+_20319519 0.59 ENSDART00000004217
coronin, actin binding protein, 1Ca
chr15_+_47525073 0.59 ENSDART00000067583
SID1 transmembrane family, member 2
chr10_-_35186310 0.59 ENSDART00000127805
POM121 transmembrane nucleoporin
chr1_+_35194454 0.58 ENSDART00000165389
sc:d189
chr22_+_737211 0.58 ENSDART00000017305
zinc finger protein 76
chr20_+_46699021 0.57 ENSDART00000167398
ENSDART00000029894
WD repeat domain 26b
chr15_+_31911989 0.56 ENSDART00000111472
breast cancer 2, early onset
chr2_-_9744081 0.56 ENSDART00000097732
dishevelled segment polarity protein 3a
chr7_-_9674073 0.55 ENSDART00000187902
leucine-rich repeat kinase 1
chr13_+_35765317 0.55 ENSDART00000100156
ENSDART00000167650
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr3_-_45777226 0.54 ENSDART00000192849
H3 histone, family 3B.1
chr24_-_13349464 0.53 ENSDART00000134482
ENSDART00000139212
telomeric repeat binding factor (NIMA-interacting) 1
chr17_+_1632294 0.53 ENSDART00000191959
signal recognition particle 14
chr18_+_35229115 0.53 ENSDART00000129624
ENSDART00000184596
transforming growth factor beta regulator 1
chr20_+_26002534 0.52 ENSDART00000147845
nuclear receptor binding protein 1
chr12_+_8569685 0.52 ENSDART00000031676
nuclear receptor binding factor 2b
chr1_+_34763539 0.52 ENSDART00000077725
ENSDART00000113808
zgc:172122
chr9_-_29643628 0.52 ENSDART00000101177
SPRY domain containing 7b
chr15_+_41815703 0.51 ENSDART00000059508
2-phosphoxylose phosphatase 1
chr15_-_26887028 0.51 ENSDART00000156292
si:dkey-243i1.1
chr9_-_12595003 0.50 ENSDART00000184900
transformer 2 beta homolog
chr17_+_7534180 0.50 ENSDART00000187512
SNF2 histone linker PHD RING helicase
chr24_-_13349802 0.50 ENSDART00000164729
telomeric repeat binding factor (NIMA-interacting) 1
chr17_+_7534365 0.50 ENSDART00000157123
SNF2 histone linker PHD RING helicase
chr10_-_28118035 0.49 ENSDART00000190836
ENSDART00000088852
mediator complex subunit 13a
chr6_+_38773376 0.49 ENSDART00000078128
ENSDART00000184053
ubiquitin protein ligase E3A
chr11_+_22623284 0.49 ENSDART00000111850
si:ch211-86h15.1
chr24_-_17400472 0.49 ENSDART00000024691
cullin 1b
chr13_+_9819194 0.49 ENSDART00000091595
family with sequence similarity 45, member A
chr18_+_15795566 0.48 ENSDART00000099944
nudix (nucleoside diphosphate linked moiety X)-type motif 4a
chr22_+_8753365 0.48 ENSDART00000106086
si:dkey-182g1.2
chr22_+_14836040 0.48 ENSDART00000180951
GTP binding protein 1, like
chr20_-_43079478 0.48 ENSDART00000060982
sorting nexin 9b
chr16_+_12812214 0.47 ENSDART00000124875
U2 small nuclear RNA auxiliary factor 2a
chr2_-_26596794 0.46 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr1_+_17527342 0.46 ENSDART00000139702
ENSDART00000140076
ENSDART00000005593
caspase 3, apoptosis-related cysteine peptidase a
chr4_+_9177997 0.46 ENSDART00000057254
ENSDART00000154614
nuclear transcription factor Y, beta a
chr2_-_22660232 0.46 ENSDART00000174742
THAP domain containing 4
chr12_-_7639120 0.46 ENSDART00000126712
ENSDART00000126219
coiled-coil domain containing 6b
chr8_-_51954562 0.45 ENSDART00000132527
ENSDART00000057315
centrosomal protein 78
chr2_+_36606019 0.44 ENSDART00000098415
inhibitor of growth family, member 5b
chr3_-_30248277 0.44 ENSDART00000133516
ENSDART00000077029
ER membrane protein complex subunit 10
chr8_-_11202378 0.43 ENSDART00000147817
ENSDART00000174039
family with sequence similarity 208, member B
chr22_+_8753092 0.43 ENSDART00000140720
si:dkey-182g1.2
chr10_-_28117740 0.42 ENSDART00000134491
mediator complex subunit 13a
chr22_+_20135443 0.42 ENSDART00000143641
eukaryotic translation elongation factor 2a, tandem duplicate 1
chr14_-_45595711 0.41 ENSDART00000074038
SCY1-like, kinase-like 1
chr12_+_27243059 0.41 ENSDART00000066269
ADP-ribosylation factor-like 4D
chr6_+_55819038 0.41 ENSDART00000108786
si:ch211-81n22.1
chr2_-_20666920 0.41 ENSDART00000143437
ENSDART00000114546
ENSDART00000136113
ENSDART00000179247
dual specificity phosphatase 12
chr24_+_37533728 0.40 ENSDART00000061203
ras homolog family member T2
chr24_+_28935200 0.39 ENSDART00000017427
RNA-binding region (RNP1, RRM) containing 3
chr6_+_11680726 0.38 ENSDART00000186732
calcitonin receptor-like b
chr12_-_33582382 0.38 ENSDART00000009794
ENSDART00000136617
tudor and KH domain containing
chr3_+_14641962 0.38 ENSDART00000091070
zgc:158403
chr25_-_13871118 0.37 ENSDART00000160866
cryptochrome circadian clock 2
chr8_+_37749263 0.37 ENSDART00000108556
ENSDART00000147942
nucleophosmin/nucleoplasmin, 2a
chr3_-_21280373 0.37 ENSDART00000003939
synaptogyrin 1a
chr9_-_12594759 0.37 ENSDART00000021266
transformer 2 beta homolog
chr24_+_39027481 0.37 ENSDART00000085565
calpain 15
chr17_+_25590127 0.37 ENSDART00000064803
isoleucyl-tRNA synthetase 2, mitochondrial
chr8_+_19621511 0.36 ENSDART00000017128
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr8_+_19621731 0.36 ENSDART00000144667
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr18_+_8402129 0.35 ENSDART00000081154
ENSDART00000171974
PRP18 pre-mRNA processing factor 18 homolog (yeast)
chr2_-_33676494 0.35 ENSDART00000141192
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr9_+_22929675 0.35 ENSDART00000061299
translin
chr16_+_12812472 0.35 ENSDART00000008535
U2 small nuclear RNA auxiliary factor 2a
chr18_+_907266 0.34 ENSDART00000171729
pyruvate kinase M1/2a
chr21_+_17005737 0.33 ENSDART00000101246
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr9_-_1200187 0.33 ENSDART00000158760
INO80 complex subunit Da
chr9_-_41507712 0.33 ENSDART00000135821
major facilitator superfamily domain containing 6b
chr21_+_6114709 0.32 ENSDART00000065858
folylpolyglutamate synthase
chr8_+_47099033 0.32 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr19_-_7070691 0.32 ENSDART00000168755
TAP binding protein (tapasin), tandem duplicate 2
chr12_-_17492852 0.31 ENSDART00000012421
ENSDART00000138766
ENSDART00000130735
multiple inositol-polyphosphate phosphatase 1b
chr8_-_17184482 0.31 ENSDART00000025803
polymerase (DNA directed), alpha 2
chr20_+_49895220 0.31 ENSDART00000097865
integrator complex subunit 9
chr1_+_41690402 0.30 ENSDART00000177298
F-box protein 41
chr10_-_40826657 0.30 ENSDART00000076304
proliferating cell nuclear antigen
chr24_+_26329018 0.29 ENSDART00000145752
myoneurin
chr6_-_17849786 0.28 ENSDART00000172709
regulatory associated protein of MTOR, complex 1
chr6_+_11681011 0.28 ENSDART00000151447
ENSDART00000151618
calcitonin receptor-like b
chr21_+_6114305 0.27 ENSDART00000141607
folylpolyglutamate synthase
chr5_-_54497319 0.26 ENSDART00000160492
aminolevulinate dehydratase
chr9_+_35832294 0.26 ENSDART00000130549
ENSDART00000122169
si:dkey-67c22.2
chr10_-_32494499 0.25 ENSDART00000129395
UV radiation resistance associated gene
chr23_+_43950674 0.25 ENSDART00000167813
corin, serine peptidase
chr13_-_14908664 0.25 ENSDART00000138867
adaptor-related protein complex 5, sigma 1 subunit
chr6_-_8704702 0.25 ENSDART00000064149
nucleic acid binding protein 1b
chr5_-_26764298 0.24 ENSDART00000189373
ring finger protein 181
chr5_+_35955209 0.24 ENSDART00000074630
zgc:103697
chr8_-_25569920 0.24 ENSDART00000136869
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ctcf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.5 1.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.5 1.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 1.0 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.3 1.9 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 1.2 GO:0046324 regulation of glucose import(GO:0046324)
0.3 0.8 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.2 1.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 0.9 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 1.2 GO:0043111 replication fork arrest(GO:0043111)
0.2 1.3 GO:0016559 peroxisome fission(GO:0016559)
0.2 1.0 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 1.5 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.2 0.8 GO:1902414 protein localization to cell junction(GO:1902414)
0.2 1.0 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.2 1.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 1.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 0.8 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.2 0.5 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.3 GO:0045444 fat cell differentiation(GO:0045444)
0.1 0.8 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.1 1.2 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 1.3 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.5 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 1.5 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 0.5 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.7 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 0.2 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1 0.3 GO:0019884 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.6 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 1.2 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.7 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 1.0 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 2.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.6 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 1.4 GO:0046660 female sex differentiation(GO:0046660)
0.1 0.8 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.9 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.4 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 1.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.7 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.3 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 2.1 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 1.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.8 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0006145 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
0.0 0.1 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:1901998 toxin transport(GO:1901998)
0.0 1.7 GO:0051057 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.1 GO:0043420 anthranilate metabolic process(GO:0043420)
0.0 1.7 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.8 GO:0007286 spermatid development(GO:0007286)
0.0 1.4 GO:0051298 centrosome duplication(GO:0051298)
0.0 2.3 GO:0034968 histone lysine methylation(GO:0034968)
0.0 1.1 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.6 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 1.8 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.6 GO:0090148 membrane fission(GO:0090148)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.2 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.0 GO:2000391 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.3 GO:0010821 regulation of mitochondrion organization(GO:0010821)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 2.2 GO:0032259 methylation(GO:0032259)
0.0 0.7 GO:0006414 translational elongation(GO:0006414)
0.0 0.4 GO:0038202 TORC1 signaling(GO:0038202)
0.0 1.3 GO:0006413 translational initiation(GO:0006413)
0.0 0.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 0.9 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.3 1.3 GO:0031415 NatA complex(GO:0031415)
0.2 1.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.0 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 1.5 GO:0005784 Sec61 translocon complex(GO:0005784)
0.2 1.2 GO:0031298 replication fork protection complex(GO:0031298)
0.2 1.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 2.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.8 GO:0089701 U2AF(GO:0089701)
0.1 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.8 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.2 GO:0070209 ASTRA complex(GO:0070209)
0.1 1.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.1 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.0 GO:0008305 integrin complex(GO:0008305)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 2.3 GO:0016607 nuclear speck(GO:0016607)
0.0 1.1 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 4.7 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.0 GO:0034709 methylosome(GO:0034709) pICln-Sm protein complex(GO:0034715)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 1.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 4.0 GO:0000323 lytic vacuole(GO:0000323)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 1.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 0.9 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.3 1.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 1.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.7 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.2 1.5 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.9 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.6 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 1.2 GO:0015232 heme transporter activity(GO:0015232)
0.2 1.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 2.3 GO:2001069 glycogen binding(GO:2001069)
0.1 2.0 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.1 2.3 GO:0002039 p53 binding(GO:0002039)
0.1 2.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.5 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.3 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 0.7 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.0 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.7 GO:0010181 FMN binding(GO:0010181)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.2 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.3 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0000049 tRNA binding(GO:0000049)
0.0 0.7 GO:0019902 phosphatase binding(GO:0019902)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.6 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.5 PID AURORA A PATHWAY Aurora A signaling
0.1 1.7 PID ATR PATHWAY ATR signaling pathway
0.0 2.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.6 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 0.8 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.5 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway