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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for creb3l1

Z-value: 0.73

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Transcription factors associated with creb3l1

Gene Symbol Gene ID Gene Info
ENSDARG00000015793 cAMP responsive element binding protein 3-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
creb3l1dr11_v1_chr7_+_38897836_38897836-0.911.7e-07Click!

Activity profile of creb3l1 motif

Sorted Z-values of creb3l1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_43636595 2.67 ENSDART00000151115
ENSDART00000151486
ENSDART00000151778
si:ch1073-263o8.2
chr18_-_7031409 2.06 ENSDART00000148485
ENSDART00000005405
calumenin b
chr12_+_30789611 1.83 ENSDART00000181501
aldehyde dehydrogenase 18 family, member A1
chr8_+_47219107 1.57 ENSDART00000146018
ENSDART00000075068
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_54124209 1.47 ENSDART00000187730

chr3_-_26184018 1.43 ENSDART00000191604
si:ch211-11k18.4
chr18_-_34549721 1.24 ENSDART00000137101
ENSDART00000021880
signal sequence receptor, gamma
chr9_+_45428041 1.11 ENSDART00000193087
adenosine deaminase, RNA-specific, B1b
chr20_+_22799857 1.10 ENSDART00000058527
sec1 family domain containing 2
chr10_+_15603082 1.06 ENSDART00000024450
zinc finger, AN1-type domain 5b
chr15_-_18115540 1.05 ENSDART00000131639
ENSDART00000047902
archain 1b
chr3_-_26183699 1.05 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr14_-_26411918 1.01 ENSDART00000020582
transmembrane p24 trafficking protein 9
chr20_+_22799641 1.01 ENSDART00000131132
sec1 family domain containing 2
chr5_-_48680580 1.00 ENSDART00000031194
LysM, putative peptidoglycan-binding, domain containing 3
chr4_-_5795309 0.97 ENSDART00000039987
phosphoglucomutase 3
chr21_+_10701834 0.94 ENSDART00000192473
lectin, mannose-binding, 1
chr21_+_10702031 0.93 ENSDART00000102304
lectin, mannose-binding, 1
chr12_+_13348918 0.92 ENSDART00000181373
ribonuclease type III, nuclear
chr19_+_7549854 0.91 ENSDART00000138866
ENSDART00000151758
pre-B-cell leukemia homeobox interacting protein 1a
chr4_-_2637689 0.90 ENSDART00000192550
ENSDART00000021953
ENSDART00000150344
component of oligomeric golgi complex 5
chr20_-_1191910 0.89 ENSDART00000043218
ubiquitin-conjugating enzyme E2, J1
chr4_+_2637947 0.84 ENSDART00000130623
dihydrouridine synthase 4-like (S. cerevisiae)
chr6_-_13716744 0.77 ENSDART00000111102
chondroitin polymerizing factor b
chr9_+_20554178 0.75 ENSDART00000183911
ENSDART00000147435
mannosidase, alpha, class 1A, member 2
chr5_-_30516646 0.71 ENSDART00000014666
archain 1a
chr5_-_28968964 0.70 ENSDART00000184936
ENSDART00000016628
family with sequence similarity 129, member Bb
chr18_-_7481036 0.70 ENSDART00000101292
si:dkey-238c7.16
chr16_+_19637384 0.70 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr10_-_3427589 0.68 ENSDART00000133452
ENSDART00000037183
transmembrane p24 trafficking protein 2
chr22_-_21897203 0.60 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr2_-_36819624 0.60 ENSDART00000140844
SLIT and NTRK-like family, member 3b
chr17_+_10090638 0.56 ENSDART00000169522
ENSDART00000160156
Sec23 homolog A, COPII coat complex component
chr16_+_5612547 0.54 ENSDART00000140226
ENSDART00000189352
si:dkey-283b15.4
chr17_-_28797395 0.52 ENSDART00000134735
sec1 family domain containing 1
chr9_-_29497916 0.52 ENSDART00000060246
DnaJ (Hsp40) homolog, subfamily C, member 3a
chr9_+_20554896 0.51 ENSDART00000144248
mannosidase, alpha, class 1A, member 2
chr23_-_31266586 0.47 ENSDART00000139746
si:dkey-261l7.2
chr18_+_7553950 0.43 ENSDART00000193420
ENSDART00000062143
zgc:77650
chr5_+_58996765 0.42 ENSDART00000062175
derlin 2
chr1_-_18592068 0.42 ENSDART00000082063
family with sequence similarity 114, member A1
chr1_+_277731 0.42 ENSDART00000133431
centromere protein E
chr14_-_45595711 0.39 ENSDART00000074038
SCY1-like, kinase-like 1
chr7_+_18100996 0.39 ENSDART00000055810
zRAB1B, member RAS oncogene family a
chr12_-_35582683 0.39 ENSDART00000167933
SEC24 homolog C, COPII coat complex component
chr18_-_18587745 0.38 ENSDART00000191973
splicing factor 3b, subunit 3
chr12_-_35582521 0.37 ENSDART00000162175
ENSDART00000168958
SEC24 homolog C, COPII coat complex component
chr3_+_26123736 0.36 ENSDART00000010477
heat shock cognate 70-kd protein, tandem duplicate 3
chr14_+_8594367 0.35 ENSDART00000037749
syntaxin 5A
chr19_+_33139164 0.35 ENSDART00000043039
family with sequence similarity 84, member B
chr4_-_26095755 0.34 ENSDART00000100611
ENSDART00000191266
si:ch211-244b2.3
chr2_+_5948534 0.32 ENSDART00000124324
ENSDART00000176461
solute carrier family 1 (glutamate transporter), member 7a
chr14_-_45464112 0.32 ENSDART00000173209
EH-domain containing 1a
chr7_+_13491452 0.31 ENSDART00000053535
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr3_-_37351225 0.30 ENSDART00000174685
si:ch211-278a6.1
chr3_+_32862730 0.28 ENSDART00000144939
ENSDART00000125126
ENSDART00000144531
ENSDART00000141717
ENSDART00000137599
zgc:162613
chr17_-_20849879 0.28 ENSDART00000088100
ENSDART00000149630
ankyrin 3b
chr17_+_30448452 0.25 ENSDART00000153939
lipin 1
chr6_-_50685862 0.24 ENSDART00000134146
metastasis suppressor 1
chr21_+_5932140 0.22 ENSDART00000193767
REX4 homolog, 3'-5' exonuclease
chr11_-_36957127 0.21 ENSDART00000168528
calcium channel, voltage-dependent, L type, alpha 1D subunit, a
chr3_-_180860 0.18 ENSDART00000059956
ENSDART00000192506
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr4_-_17812131 0.17 ENSDART00000025731
Spi-C transcription factor (Spi-1/PU.1 related)
chr9_+_19529951 0.17 ENSDART00000125416
pbx/knotted 1 homeobox 1.1
chr23_+_17878969 0.14 ENSDART00000154934
ENSDART00000154140
ENSDART00000156331
si:ch73-390p7.2
chr7_+_30988570 0.13 ENSDART00000180613
ENSDART00000185625
tight junction protein 1a
chr13_-_40499296 0.13 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr15_-_41245962 0.12 ENSDART00000155359
single-pass membrane protein with coiled-coil domains 4
chr18_-_3542435 0.11 ENSDART00000184017
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr22_+_31295791 0.10 ENSDART00000092447
glutamate receptor interacting protein 2b
chr17_-_39880725 0.10 ENSDART00000184030
zmp:0000000545
chr5_+_54685175 0.09 ENSDART00000115016
pro-melanin-concentrating hormone, like
chr6_-_59388625 0.09 ENSDART00000111992
protein phosphatase 1, regulatory subunit 16B
chr11_-_2456656 0.08 ENSDART00000171219
ENSDART00000167938
solute carrier family 2 (facilitated glucose transporter), member 10
chr7_-_30177691 0.08 ENSDART00000046689
transmembrane p24 trafficking protein 3
chr1_-_7930679 0.07 ENSDART00000146090
si:dkey-79f11.10
chr20_-_22464250 0.06 ENSDART00000165904
platelet-derived growth factor receptor, alpha polypeptide
chr9_-_49464993 0.06 ENSDART00000181471
xin actin binding repeat containing 2b
chr22_-_10482253 0.04 ENSDART00000143164
asporin (LRR class 1)
chr17_-_11417551 0.04 ENSDART00000128291
AT rich interactive domain 4A (RBP1-like)
chr20_-_38617766 0.03 ENSDART00000050474
solute carrier family 30 (zinc transporter), member 2
chr22_-_14346575 0.02 ENSDART00000136326
si:dkeyp-122a9.1
chr7_-_58826164 0.01 ENSDART00000171095
SRY (sex determining region Y)-box 32
chr19_-_43552252 0.01 ENSDART00000138308
G protein-coupled receptor 186
chr5_-_25066780 0.00 ENSDART00000002118
ENSDART00000182575
patatin-like phospholipase domain containing 7b

Network of associatons between targets according to the STRING database.

First level regulatory network of creb3l1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0051645 Golgi localization(GO:0051645)
0.3 1.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 1.8 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.9 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 1.6 GO:0009086 methionine biosynthetic process(GO:0009086) tetrahydrofolate interconversion(GO:0035999)
0.1 1.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 1.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.0 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 2.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 2.9 GO:0007030 Golgi organization(GO:0007030)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 2.9 GO:0016197 endosomal transport(GO:0016197)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:0048278 vesicle docking(GO:0048278)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 1.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.4 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 1.9 GO:0005537 mannose binding(GO:0005537)
0.1 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.8 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.0 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 2.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0051087 chaperone binding(GO:0051087)
0.0 1.1 GO:0000149 SNARE binding(GO:0000149)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 4.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters