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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for bcl6aa+bcl6ab+bcl6b

Z-value: 0.28

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Transcription factors associated with bcl6aa+bcl6ab+bcl6b

Gene Symbol Gene ID Gene Info
ENSDARG00000069295 BCL6A transcription repressor b
ENSDARG00000069335 BCL6B transcription repressor
ENSDARG00000070864 BCL6A transcription repressor a
ENSDARG00000111395 BCL6A transcription repressor a
ENSDARG00000112502 BCL6A transcription repressor a
ENSDARG00000116260 BCL6A transcription repressor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bcl6bdr11_v1_chr7_+_20017211_200172110.941.1e-08Click!
bcl6abdr11_v1_chr2_-_10098191_100981910.744.3e-04Click!
bcl6adr11_v1_chr6_-_28222592_28222592-0.625.8e-03Click!

Activity profile of bcl6aa+bcl6ab+bcl6b motif

Sorted Z-values of bcl6aa+bcl6ab+bcl6b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_17964525 1.33 ENSDART00000018948
cytokine inducible SH2-containing protein b
chr10_+_40324395 1.19 ENSDART00000147205
glycolipid transfer protein b
chr6_-_40352215 0.94 ENSDART00000103992
tubulin tyrosine ligase-like family, member 3
chr24_+_31361407 0.91 ENSDART00000162668
cAMP responsive element modulator b
chr17_+_7522777 0.89 ENSDART00000184723
kelch-like family member 10b, tandem duplicate 2
chr12_-_27242498 0.82 ENSDART00000152609
ENSDART00000152170
si:dkey-11c5.11
chr16_-_54465271 0.82 ENSDART00000185978
cytochrome P450, family 11, subfamily C, polypeptide 1
chr14_-_24397718 0.80 ENSDART00000110164
si:ch211-163m17.4
chr13_-_11967769 0.74 ENSDART00000158369
zgc:110197
chr9_+_40825065 0.74 ENSDART00000137673
si:dkey-95p16.2
chr22_-_3344613 0.72 ENSDART00000165600
thromboxane A2 receptor
chr20_+_39457598 0.72 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr21_+_35215810 0.70 ENSDART00000135256
ubiquitin domain containing 2
chr23_-_35483163 0.66 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
F-box protein 25
chr20_-_43533096 0.61 ENSDART00000145199
Pim proto-oncogene, serine/threonine kinase, related 134
chr13_-_37608441 0.60 ENSDART00000140230
zgc:123068
chr8_-_23783633 0.58 ENSDART00000132657
si:ch211-163l21.7
chr13_-_37642890 0.54 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
chr18_+_25752592 0.53 ENSDART00000111767
si:ch211-39k3.2
chr6_+_48041759 0.53 ENSDART00000140086
si:dkey-92f12.2
chr20_+_23440632 0.49 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
chr4_-_8152746 0.48 ENSDART00000012928
ENSDART00000177482
WNK lysine deficient protein kinase 1b
chr2_-_10703621 0.47 ENSDART00000005944
ribosomal protein L5a
chr9_+_26103814 0.46 ENSDART00000026011
ephrin-B2a
chr4_+_19127973 0.46 ENSDART00000136611
si:dkey-21o22.2
chr21_+_26720803 0.44 ENSDART00000053797
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr14_-_21123325 0.43 ENSDART00000180889
ENSDART00000188539
si:dkey-74k8.4
chr3_-_60602432 0.42 ENSDART00000163235
serine/arginine-rich splicing factor 2b
chr22_+_7480465 0.42 ENSDART00000034545
zgc:92745
chr17_-_24564674 0.41 ENSDART00000105435
ENSDART00000135086
ATP-binding cassette, sub-family H, member 1
chr10_-_3332362 0.39 ENSDART00000007577
ENSDART00000055140
torsin family 4, member Aa
chr16_-_41004731 0.39 ENSDART00000102591
si:dkey-201i6.2
chr6_+_12865137 0.38 ENSDART00000090065
family with sequence similarity 117, member Ba
chr22_-_16180467 0.38 ENSDART00000171331
ENSDART00000185607
vascular cell adhesion molecule 1b
chr7_+_32369026 0.38 ENSDART00000169588
leucine-rich repeat containing G protein-coupled receptor 4
chr3_-_55139127 0.38 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr14_+_31651533 0.37 ENSDART00000172835
four and a half LIM domains 1a
chr22_-_37611681 0.37 ENSDART00000028085
tetratricopeptide repeat domain 14
chr20_-_43495506 0.36 ENSDART00000170679
Pim proto-oncogene, serine/threonine kinase, related 132
chr4_+_12342173 0.36 ENSDART00000161518
Pim proto-oncogene, serine/threonine kinase, related 214
chr7_+_38509333 0.36 ENSDART00000153482
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr3_-_31655796 0.36 ENSDART00000181052

chr1_-_9114936 0.35 ENSDART00000163624
ENSDART00000132910
si:ch211-14k19.8
vascular associated protein
chr7_+_61876641 0.35 ENSDART00000165409

chr4_-_12323228 0.34 ENSDART00000081089
interleukin 17 receptor A1a
chr21_+_17956024 0.33 ENSDART00000142468
dynein, axonemal, intermediate chain 1, paralog 2
chr22_+_37902976 0.32 ENSDART00000169327
potassium voltage-gated channel, subfamily H (eag-related), member 1a
chr8_-_39654669 0.32 ENSDART00000145677
si:dkey-63d15.12
chr11_+_30321116 0.32 ENSDART00000187921
ENSDART00000127075
UDP glucuronosyltransferase 1 family, polypeptide B1
chr14_+_11457500 0.32 ENSDART00000169202
si:ch211-153b23.5
chr25_+_25438165 0.30 ENSDART00000161369
si:ch211-103e16.5
chr19_-_23892243 0.30 ENSDART00000132384
si:dkey-222b8.4
chr6_-_35446110 0.29 ENSDART00000058773
regulator of G protein signaling 16
chr23_-_19715799 0.29 ENSDART00000142072
ENSDART00000032744
ENSDART00000131860
ribosomal protein L10
chr23_-_14830627 0.29 ENSDART00000134659
Src-like-adaptor 2
chr3_-_55121125 0.28 ENSDART00000125092
hemoglobin, alpha embryonic 1
chr4_+_12367546 0.28 ENSDART00000161860
Pim proto-oncogene, serine/threonine kinase, related 169
chr3_-_13461056 0.27 ENSDART00000137678
F-box and WD repeat domain containing 9
chr5_+_13359146 0.27 ENSDART00000179839
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr5_-_32882162 0.27 ENSDART00000085769
leucine rich repeat and sterile alpha motif containing 1
chr21_-_22715297 0.27 ENSDART00000065548
complement component 1, q subcomponent, B chain
chr12_+_7491690 0.27 ENSDART00000152564
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr1_+_30083578 0.27 ENSDART00000101779
ENSDART00000143639
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr13_+_6092135 0.27 ENSDART00000162738
family with sequence similarity 120B
chr16_-_45917322 0.27 ENSDART00000060822
antifreeze protein type IV
chr24_-_37472727 0.27 ENSDART00000134152
clusterin associated protein 1
chr6_+_43015916 0.26 ENSDART00000064888
T cell leukemia translocation altered
chr19_-_7240627 0.25 ENSDART00000181874

chr24_+_9590188 0.25 ENSDART00000137092
si:dkey-96n2.1
chr7_+_52766211 0.25 ENSDART00000186191
diphosphoinositol pentakisphosphate kinase 1a
chr15_-_23793641 0.25 ENSDART00000122891
transmembrane protein 97
chr21_-_2238277 0.24 ENSDART00000165754
si:dkey-50i6.6
chr2_+_3428357 0.24 ENSDART00000125967

chr4_-_18436899 0.24 ENSDART00000141671
suppressor of cytokine signaling 2
chr14_-_5678457 0.24 ENSDART00000012116
T cell leukemia homeobox 2
chr7_+_26029672 0.24 ENSDART00000101126
arachidonate 12-lipoxygenase
chr6_+_9881093 0.24 ENSDART00000151558
si:ch211-222n4.6
chr5_+_63668735 0.23 ENSDART00000134261
ENSDART00000097330
dynamin 1b
chr13_-_47554194 0.23 ENSDART00000181508
acyl-CoA oxidase-like
chr5_+_25072894 0.23 ENSDART00000012268
mitochondrial ribosomal protein L41
chr14_+_24241241 0.23 ENSDART00000022377
NK2 homeobox 5
chr3_-_52661242 0.23 ENSDART00000138018
zgc:113210
chr3_-_13461361 0.23 ENSDART00000080807
F-box and WD repeat domain containing 9
chr23_+_19670085 0.22 ENSDART00000031872
potassium channel tetramerization domain containing 6b
chr19_+_5418006 0.22 ENSDART00000132874
eukaryotic translation initiation factor 1B
chr18_-_16801033 0.22 ENSDART00000100100
adrenomedullin b
chr5_+_4366431 0.22 ENSDART00000168560
ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr14_-_38828057 0.21 ENSDART00000186088
spindle apparatus coiled-coil protein 1
chr9_+_23748342 0.20 ENSDART00000019053
Fas apoptotic inhibitory molecule a
chr4_+_359970 0.20 ENSDART00000139832
transmembrane protein 181
chr1_-_26398361 0.20 ENSDART00000160183
pyrophosphatase (inorganic) 2
chr16_+_46294337 0.20 ENSDART00000040769
nuclear receptor subfamily 2, group F, member 5
chr20_-_47188966 0.19 ENSDART00000152965
si:dkeyp-104f11.9
chr3_-_55128258 0.19 ENSDART00000101734
hemoglobin, alpha embryonic 1
chr7_+_25053331 0.19 ENSDART00000173998
si:dkey-23i12.7
chr21_-_27338639 0.19 ENSDART00000130632
hypoxia-inducible factor 1, alpha subunit, like 2
chr14_+_6159356 0.19 ENSDART00000157730
Bernardinelli-Seip congenital lipodystrophy 2, like
chr3_-_44059902 0.19 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
interleukin 4 receptor, tandem duplicate 1
chr3_-_60316118 0.18 ENSDART00000171458
si:ch211-214b16.2
chr3_+_32492467 0.18 ENSDART00000151329
transient receptor potential cation channel, subfamily M, member 4a
chr4_+_47257854 0.18 ENSDART00000173868
crestin
chr6_+_11989537 0.18 ENSDART00000190817
bromodomain adjacent to zinc finger domain, 2Ba
chr19_+_25504645 0.18 ENSDART00000143292
collagen, type XXVIII, alpha 1a
chr16_-_36834505 0.18 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
purine nucleoside phosphorylase 4b
chr13_-_8888334 0.18 ENSDART00000059881
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr6_-_35106425 0.18 ENSDART00000165139
nitric oxide synthase 1 (neuronal) adaptor protein a
chr3_-_7147226 0.18 ENSDART00000178155

chr7_-_22941472 0.18 ENSDART00000190334
TNF superfamily member 10, like
chr5_+_24179307 0.18 ENSDART00000051552
mannose-P-dolichol utilization defect 1a
chr3_-_44012748 0.17 ENSDART00000167248
ENSDART00000157463
ENSDART00000159111
interleukin 4 receptor, tandem duplicate 1
chr20_+_53521648 0.17 ENSDART00000139794
p21 protein (Cdc42/Rac)-activated kinase 6b
chr15_-_2010926 0.17 ENSDART00000155688
dedicator of cytokinesis 10
chr8_+_30671060 0.17 ENSDART00000193749
adenosine A2a receptor a
chr18_-_14860435 0.17 ENSDART00000018502
mitogen-activated protein kinase 12a
chr7_+_32369463 0.17 ENSDART00000180544
leucine-rich repeat containing G protein-coupled receptor 4
chr22_-_15578402 0.17 ENSDART00000062986
hematopoietic SH2 domain containing
chr10_-_8358396 0.17 ENSDART00000059322
chondroitin sulfate N-acetylgalactosaminyltransferase 1a
chr19_+_32856907 0.17 ENSDART00000148232
ribosomal protein L30
chr21_-_2217685 0.17 ENSDART00000159315
si:dkey-50i6.5
chr9_-_23922011 0.17 ENSDART00000145734
collagen, type VI, alpha 3
chr18_+_50907675 0.16 ENSDART00000159950
si:ch1073-450f2.1
chr9_+_2002701 0.16 ENSDART00000082329
even-skipped homeobox 2
chr8_-_41228530 0.16 ENSDART00000165949
ENSDART00000173055
fumarylacetoacetate hydrolase domain containing 2A
chr7_+_50448478 0.16 ENSDART00000098815
serine incorporator 4
chr24_+_11381400 0.16 ENSDART00000058703
atypical chemokine receptor 4b
chr9_-_21912227 0.16 ENSDART00000145576
LIM domain 7a
chr22_+_1462177 0.16 ENSDART00000164685
si:dkeyp-53d3.5
chr2_+_327081 0.16 ENSDART00000155595
zgc:174263
chr4_-_67969695 0.16 ENSDART00000190016
si:ch211-223k15.1
chr15_-_3282220 0.16 ENSDART00000092942
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr20_+_52458765 0.15 ENSDART00000057980
tissue specific transplantation antigen P35B
chr3_+_62236443 0.15 ENSDART00000180482
ENSDART00000193718

chr11_-_38914265 0.15 ENSDART00000141229
si:ch211-122l14.4
chr15_-_40246396 0.15 ENSDART00000063777
potassium inwardly-rectifying channel, subfamily J, member 13
chr19_-_41405187 0.15 ENSDART00000038038
ENSDART00000172350
SEM1, 26S proteasome complex subunit
chr19_-_35428815 0.15 ENSDART00000169006
ENSDART00000003167
adenylate kinase 2
chr14_-_28567845 0.15 ENSDART00000126095
preproinsulin b
chr14_-_24410673 0.15 ENSDART00000125923
chemokine (C-X-C motif) ligand 14
chr17_+_10318071 0.14 ENSDART00000161844
forkhead box A1
chr1_+_10318089 0.14 ENSDART00000029774
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr20_+_25552057 0.14 ENSDART00000102913
cytochrome P450, family 2, subfamily V, polypeptide 1
chr10_+_21722892 0.14 ENSDART00000162855
protocadherin 1 gamma 13
chr9_-_6372535 0.14 ENSDART00000149189
esophageal cancer related gene 4a
chr8_-_19246342 0.14 ENSDART00000147172
abhydrolase domain containing 17Ab
chr20_-_23440955 0.14 ENSDART00000153386
solute carrier family 10, member 4
chr17_-_48743076 0.13 ENSDART00000173117
potassium channel, subfamily K, member 17
chr9_+_6934491 0.13 ENSDART00000114323
major facilitator superfamily domain containing 9
chr10_-_4375190 0.13 ENSDART00000016102

chr15_+_23550890 0.13 ENSDART00000009796
ENSDART00000152720
si:dkey-31m14.7
chr5_-_25582721 0.13 ENSDART00000123986
annexin A1a
chr24_-_33291784 0.13 ENSDART00000124938
si:ch1073-406l10.2
chr21_-_18982337 0.13 ENSDART00000147246
si:ch211-222n4.6
chr1_-_58664854 0.13 ENSDART00000109528
adhesion G protein-coupled receptor E5b, duplicate 3
chr19_-_6134802 0.13 ENSDART00000140051
capicua transcriptional repressor a
chr5_-_42872712 0.13 ENSDART00000003947
flotillin 2a
chr16_+_25343934 0.13 ENSDART00000109710
zinc finger and AT hook domain containing
chr22_+_3238474 0.13 ENSDART00000157954
si:ch1073-178p5.3
chr21_+_45626136 0.13 ENSDART00000158742
interferon regulatory factor 1b
chr1_+_49673489 0.12 ENSDART00000135487
testis specific, 10
chr20_-_38446891 0.12 ENSDART00000192013
inositol-trisphosphate 3-kinase B
chr20_-_39391833 0.12 ENSDART00000135149
si:dkey-217m5.8
chr6_-_8498908 0.12 ENSDART00000149222
peptidoglycan recognition protein 2
chr13_-_37631092 0.12 ENSDART00000108855
si:dkey-188i13.7
chr11_-_36350876 0.12 ENSDART00000146495
ENSDART00000020655
proteasome subunit alpha 5
chr4_+_74141400 0.12 ENSDART00000166994
tripartite motif containing 24
chr10_+_21730585 0.12 ENSDART00000188576
protocadherin 1 gamma 22
chr9_-_54304684 0.12 ENSDART00000109512
interleukin 13
chr21_+_26073104 0.12 ENSDART00000193273
ribosomal protein L23a
chr13_-_49819027 0.11 ENSDART00000067824
beta-1,3-N-acetylgalactosaminyltransferase 2
chr24_+_10397865 0.11 ENSDART00000155557
si:ch211-69l10.4
chr22_-_27706576 0.11 ENSDART00000188564

chr1_-_9195629 0.11 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr21_-_2248239 0.11 ENSDART00000169448
si:ch73-299h12.1
chr18_+_13315739 0.11 ENSDART00000143404
si:ch211-260p9.3
chr19_-_38611814 0.11 ENSDART00000151958
collagen, type XVI, alpha 1
chr23_+_42292748 0.10 ENSDART00000166113
ENSDART00000158684
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr24_-_21991770 0.10 ENSDART00000147296
si:rp71-1f1.4
chr22_+_34691020 0.10 ENSDART00000192202
hydroxylysine kinase, tandem duplicate 1
chr16_+_25809235 0.10 ENSDART00000181196
immunity-related GTPase family, q1
chrM_+_4993 0.10 ENSDART00000093600
NADH dehydrogenase 2, mitochondrial
chr18_+_18863167 0.10 ENSDART00000091094
plasmolipin
chr9_+_29585943 0.10 ENSDART00000185989
ENSDART00000115290
mcf.2 cell line derived transforming sequence-like b
chr19_-_5351980 0.10 ENSDART00000163304
ENSDART00000027701
keratin 92
chr23_-_19682971 0.10 ENSDART00000048891
zgc:193598
chr3_+_19299309 0.10 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr4_+_5642696 0.10 ENSDART00000028941
mitochondrial ribosomal protein S18A
chr4_-_13548806 0.09 ENSDART00000067155
interleukin 22
chr9_-_370225 0.09 ENSDART00000163637
si:dkey-11f4.7
chr17_-_608857 0.09 ENSDART00000163431
kelch like family member 28
chr24_-_37877743 0.09 ENSDART00000105658
transmembrane protein 204
chr18_+_37259800 0.09 ENSDART00000078053
ENSDART00000132577
tubulin folding cofactor B
chr5_-_55600689 0.09 ENSDART00000013229
guanine nucleotide binding protein (G protein), q polypeptide
chr24_+_7828097 0.09 ENSDART00000134975
zgc:101569
chr13_+_33688474 0.09 ENSDART00000161465

chr19_-_35229336 0.09 ENSDART00000054274
microtubule-actin crosslinking factor 1a
chr6_+_32834007 0.09 ENSDART00000157353
cylindromatosis (turban tumor syndrome), like
chr9_-_32813177 0.09 ENSDART00000012694
myxovirus (influenza virus) resistance C
chr19_-_3742472 0.08 ENSDART00000162132
bloodthirsty-related gene family, member 22
chr11_-_22303678 0.08 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr10_+_22134606 0.08 ENSDART00000155228
si:dkey-4c2.11

Network of associatons between targets according to the STRING database.

First level regulatory network of bcl6aa+bcl6ab+bcl6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0035627 ceramide transport(GO:0035627)
0.2 0.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.5 GO:0007412 axon target recognition(GO:0007412)
0.1 0.6 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.4 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.2 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.7 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.1 0.2 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.1 0.2 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.2 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.4 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.4 GO:0021576 hindbrain formation(GO:0021576)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.5 GO:1901381 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.1 GO:0072020 proximal straight tubule development(GO:0072020)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:0033034 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.0 0.2 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0071887 leukocyte apoptotic process(GO:0071887)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.0 0.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.5 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.0 GO:0002839 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.0 GO:0055026 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 0.3 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) syncytium formation(GO:0006949)
0.0 0.1 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) regulation of mitophagy(GO:1903146)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0050688 regulation of response to biotic stimulus(GO:0002831) regulation of defense response to virus(GO:0050688)
0.0 0.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.9 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.0 GO:0005930 axoneme(GO:0005930)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.2 1.2 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.7 GO:0004960 thromboxane receptor activity(GO:0004960)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.2 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.2 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.1 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels