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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for bcl11aa

Z-value: 0.52

Motif logo

Transcription factors associated with bcl11aa

Gene Symbol Gene ID Gene Info
ENSDARG00000061352 BAF chromatin remodeling complex subunit BCL11A a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bcl11aadr11_v1_chr13_+_25846528_25846528-0.475.0e-02Click!

Activity profile of bcl11aa motif

Sorted Z-values of bcl11aa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_11923701 0.49 ENSDART00000109292
ubiquitin associated protein 2a
chr9_+_38457806 0.45 ENSDART00000142512
minichromosome maintenance complex component 3 associated protein
chr23_+_30898013 0.45 ENSDART00000146859
Cdk5 and Abl enzyme substrate 2a
chr9_+_38458193 0.44 ENSDART00000008053
minichromosome maintenance complex component 3 associated protein
chr8_+_44703864 0.43 ENSDART00000016225
steroidogenic acute regulatory protein
chr6_-_16394528 0.42 ENSDART00000089445
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr14_+_24845941 0.42 ENSDART00000187513
Rho guanine nucleotide exchange factor (GEF) 37
chr25_+_4541211 0.38 ENSDART00000129978
patatin-like phospholipase domain containing 2
chr25_+_18953756 0.37 ENSDART00000154291
thymine DNA glycosylase, tandem duplicate 2
chr19_-_11425542 0.36 ENSDART00000177875
ENSDART00000080762
septin 7a
chr6_+_38626926 0.33 ENSDART00000190339
ATPase phospholipid transporting 10A
chr20_-_18789543 0.33 ENSDART00000182240
cerebral cavernous malformation 2
chr7_-_26263183 0.33 ENSDART00000079357
ENSDART00000190369
ENSDART00000193154
ENSDART00000101109
adaptor-related protein complex 1, sigma 1 subunit
chr7_-_26262978 0.33 ENSDART00000137769
adaptor-related protein complex 1, sigma 1 subunit
chr3_-_31833266 0.32 ENSDART00000084932
ENSDART00000183617
mitogen-activated protein kinase kinase kinase 3
chr25_-_14637660 0.32 ENSDART00000143666
neuron navigator 2b
chr2_+_3516913 0.31 ENSDART00000109346

chr24_+_31361407 0.31 ENSDART00000162668
cAMP responsive element modulator b
chr2_+_36046126 0.31 ENSDART00000085976
ENSDART00000171680
SMG7 nonsense mediated mRNA decay factor
chr13_+_11829072 0.29 ENSDART00000079356
ENSDART00000170160
suppressor of fused homolog (Drosophila)
chr2_+_21855036 0.29 ENSDART00000140012
carbonic anhydrase VIII
chr5_-_38384289 0.29 ENSDART00000135260
misshapen-like kinase 1
chr18_+_27571448 0.28 ENSDART00000147886
CD82 molecule b
chr16_+_10963602 0.27 ENSDART00000141032
POU class 2 homeobox 2a
chr24_+_39277043 0.27 ENSDART00000165458
si:ch73-103b11.2
chr11_+_18216404 0.27 ENSDART00000086437
transmembrane and coiled-coil domain family 1b
chr4_+_23117557 0.27 ENSDART00000066909
solute carrier family 35, member E3
chr11_+_4026229 0.27 ENSDART00000041417
calcium/calmodulin-dependent protein kinase Ib
chr8_+_23381892 0.26 ENSDART00000180950
ENSDART00000063010
ENSDART00000074241
ENSDART00000142783
microtubule-associated protein, RP/EB family, member 1a
chr19_+_29798064 0.26 ENSDART00000167803
ENSDART00000051804
MARCKS-like 1b
chr25_+_18954189 0.25 ENSDART00000123207
thymine DNA glycosylase, tandem duplicate 2
chr7_+_39706004 0.25 ENSDART00000161856
chemokine (C-C motif) ligand 36, duplicate 1
chr19_-_20403318 0.25 ENSDART00000136826
deleted in azoospermia-like
chr16_+_28547157 0.24 ENSDART00000109450
ENSDART00000165687
family with sequence similarity 171, member A1
chr9_+_30112423 0.24 ENSDART00000112398
ENSDART00000013591
trk-fused gene
chr11_-_12801157 0.24 ENSDART00000103449
taxilin gamma
chr9_+_33267211 0.24 ENSDART00000025635
ubiquitin specific peptidase 9
chr11_-_12800945 0.23 ENSDART00000191178
taxilin gamma
chr8_-_43456025 0.23 ENSDART00000001092
ENSDART00000140618
nuclear receptor corepressor 2
chr23_+_21978816 0.23 ENSDART00000087110
eukaryotic translation initiation factor 4 gamma, 3b
chr15_+_39977461 0.23 ENSDART00000063786
calcium binding protein 39
chr9_+_51655636 0.23 ENSDART00000169908
RNA binding motif single stranded interacting protein 1
chr22_-_31517300 0.22 ENSDART00000164799
solute carrier family 6 (neurotransmitter transporter), member 6b
chr17_-_10043273 0.22 ENSDART00000156078
bromodomain adjacent to zinc finger domain, 1A
chr5_-_43682930 0.22 ENSDART00000075017
si:dkey-40c11.1
chr2_+_21855291 0.21 ENSDART00000186204
carbonic anhydrase VIII
chr7_+_59677273 0.20 ENSDART00000039535
ENSDART00000132044
tRNA methyltransferase 44 homolog
chr16_-_13612650 0.19 ENSDART00000080372
D site albumin promoter binding protein b
chr2_+_22694382 0.19 ENSDART00000139196
kinesin family member 1Ab
chr16_+_19014886 0.19 ENSDART00000079298
si:ch211-254p10.2
chr7_-_30553588 0.19 ENSDART00000139546
SAFB-like, transcription modulator
chr22_-_20309283 0.18 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
chr22_-_10397600 0.18 ENSDART00000181964
ENSDART00000142886
nischarin
chr8_+_45294767 0.17 ENSDART00000191527
ubiquitin associated protein 2b
chr3_+_54761569 0.16 ENSDART00000135913
ENSDART00000180983
si:ch211-74m13.1
chr25_+_15997957 0.16 ENSDART00000140047
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr5_+_61556172 0.16 ENSDART00000131937
ORAI calcium release-activated calcium modulator 2
chr2_-_21786826 0.15 ENSDART00000016208
chromodomain helicase DNA binding protein 7
chr3_+_22335030 0.15 ENSDART00000055676
zgc:103564
chr5_+_28313824 0.15 ENSDART00000135878
si:dkeyp-86b9.1
chr4_-_19742300 0.15 ENSDART00000066964
ENSDART00000100952
hepatocyte growth factor a
chr8_+_10835456 0.15 ENSDART00000151388
mitogen-activated protein kinase 13
chr25_+_30238021 0.15 ENSDART00000123220
alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
chr23_+_21978584 0.15 ENSDART00000145172
eukaryotic translation initiation factor 4 gamma, 3b
chr16_-_22863603 0.14 ENSDART00000098400
ENSDART00000183963
SHC (Src homology 2 domain containing) transforming protein 1
chr2_+_48288461 0.14 ENSDART00000141495
hes family bHLH transcription factor 6
chr12_-_19279103 0.14 ENSDART00000186669
si:ch211-141o9.10
chr5_+_24156170 0.14 ENSDART00000136570
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr3_+_28576173 0.14 ENSDART00000151189
septin 12
chr16_-_22863348 0.14 ENSDART00000147609
SHC (Src homology 2 domain containing) transforming protein 1
chr5_-_38122126 0.14 ENSDART00000141791
ENSDART00000170528
si:ch211-284e13.6
chr25_+_31929325 0.13 ENSDART00000181095
amyloid beta (A4) precursor protein-binding, family A, member 2a
chr7_+_46368520 0.13 ENSDART00000192821
zinc finger protein 536
chr2_+_24786765 0.13 ENSDART00000141030
phosphodiesterase 4C, cAMP-specific a
chr19_+_19786117 0.13 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr5_-_41933912 0.12 ENSDART00000097574
nuclear receptor corepressor 1
chr4_+_16710001 0.12 ENSDART00000035899
plakophilin 2
chr24_-_21921262 0.12 ENSDART00000186061
ENSDART00000187846
transgelin 3b
chr2_-_14387335 0.12 ENSDART00000189332
ENSDART00000164786
ENSDART00000188572
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr5_-_63425428 0.12 ENSDART00000163246
centriolin
chr5_+_13359146 0.12 ENSDART00000179839
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr9_-_31108285 0.12 ENSDART00000003193
G protein-coupled receptor 183a
chr13_-_6081803 0.11 ENSDART00000099224
deltaD
chr22_-_17729778 0.11 ENSDART00000192132
si:ch73-63e15.2
chr2_-_24369087 0.11 ENSDART00000081237
plasmalemma vesicle associated protein a
chr12_+_28856151 0.11 ENSDART00000152969
nuclear factor, erythroid 2-like 1b
chr13_-_3324764 0.10 ENSDART00000102748
ENSDART00000114040
ubiquitin protein ligase E3 component n-recognin 2
chr16_+_50741154 0.10 ENSDART00000101627
zgc:110372
chr7_+_56735195 0.10 ENSDART00000082830
KIAA0895 like
chr18_+_19131773 0.10 ENSDART00000060766
RAB11a, member RAS oncogene family
chr6_+_45918981 0.10 ENSDART00000149642
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr18_+_35742838 0.10 ENSDART00000088504
ENSDART00000140386
RAS guanyl releasing protein 4
chr23_-_18567088 0.09 ENSDART00000192371
selenophosphate synthetase 2
chr3_+_22905341 0.09 ENSDART00000111435
histone deacetylase 5
chr19_-_34011340 0.09 ENSDART00000172618
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr4_+_20255160 0.09 ENSDART00000188658
leucine-rich repeats and transmembrane domains 2a
chr22_+_22438783 0.09 ENSDART00000147825
kinesin family member 14
chr20_+_34543365 0.09 ENSDART00000152073
si:ch211-242b18.1
chr4_+_12031958 0.08 ENSDART00000044154
troponin T2c, cardiac
chr19_-_7144548 0.08 ENSDART00000147177
ENSDART00000134850
proteasome subunit beta 8A
proteasome subunit beta 13a
chr1_+_33217911 0.08 ENSDART00000136761
protein kinase, X-linked
chr14_-_30967284 0.08 ENSDART00000149435
interleukin 2 receptor, gamma b
chr11_-_11965033 0.07 ENSDART00000193683
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr24_-_18877118 0.07 ENSDART00000092783
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr17_-_8899323 0.07 ENSDART00000081590
NK-lysin tandem duplicate 1
chr16_+_27957808 0.07 ENSDART00000133696
zinc finger protein 804B
chr6_-_21830405 0.07 ENSDART00000151803
ENSDART00000113497
SET domain containing 5
chr19_+_7552699 0.07 ENSDART00000180788
ENSDART00000115058
pre-B-cell leukemia homeobox interacting protein 1a
chr13_+_24834199 0.07 ENSDART00000101274
zgc:153981
chr15_+_37412883 0.07 ENSDART00000156474
zinc finger and BTB domain containing 32
chr17_-_45254585 0.06 ENSDART00000185507
ENSDART00000172080
tau tubulin kinase 2a
chr4_+_5215950 0.06 ENSDART00000140613
polypeptide N-acetylgalactosaminyltransferase 8b, tandem duplicate 2
chr11_-_40647190 0.06 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
family with sequence similarity 213, member B
chr25_-_22889519 0.05 ENSDART00000128250
MOB kinase activator 2a
chr25_-_35996141 0.05 ENSDART00000149074
spalt-like transcription factor 1b
chr17_+_26569601 0.05 ENSDART00000153897
neuron-derived neurotrophic factor , like
chr24_-_18876877 0.05 ENSDART00000186269
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr18_-_2639351 0.05 ENSDART00000168106
RELT, TNF receptor
chr15_-_34567370 0.05 ENSDART00000099793
sclerostin domain containing 1a
chr17_+_23770848 0.05 ENSDART00000079646
potassium channel, subfamily K, member 18
chr16_+_26439518 0.05 ENSDART00000041787
tripartite motif containing 35-28
chr13_+_31177934 0.05 ENSDART00000144568
protein tyrosine phosphatase, non-receptor type 20
chr6_+_6780873 0.05 ENSDART00000011865
Sec23 homolog B, COPII coat complex component
chr2_+_12255568 0.05 ENSDART00000184164
ENSDART00000013454
phosphoribosyl transferase domain containing 1
chr5_-_60885935 0.04 ENSDART00000128350
RAD51 paralog D
chr3_-_56924654 0.04 ENSDART00000157038
HID1 domain containing a
chr7_-_2163361 0.04 ENSDART00000173654
si:cabz01007812.1
chr9_+_13986427 0.04 ENSDART00000147200
CD28 molecule
chr17_+_1627379 0.04 ENSDART00000184050

chr25_-_20049449 0.04 ENSDART00000104315
zgc:136858
chr9_+_41612642 0.04 ENSDART00000138473
SPEG complex locus b
chr16_+_26747766 0.04 ENSDART00000183257
RAD54 homolog B (S. cerevisiae)
chr5_+_54422941 0.04 ENSDART00000175157
Tnf receptor-associated factor 2b
chr24_+_13635108 0.04 ENSDART00000183008
transient receptor potential cation channel, subfamily A, member 1b
chr20_-_14054083 0.04 ENSDART00000009549
Rh associated glycoprotein
chr2_+_32796873 0.03 ENSDART00000077511
chemokine (C-C motif) receptor 9a
chr17_+_15433671 0.03 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr16_+_11724230 0.03 ENSDART00000060266
carcinoembryonic antigen-related cell adhesion molecule 1
chr24_+_37722048 0.03 ENSDART00000191918
RAB11 family interacting protein 3 (class II)
chr11_+_8129536 0.03 ENSDART00000158112
ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr16_+_38820660 0.03 ENSDART00000182538
ENSDART00000189879
thyrotropin-releasing hormone receptor a
chr11_+_30057762 0.02 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr5_-_41860556 0.02 ENSDART00000140154
si:dkey-65b12.12
chr1_+_23398405 0.02 ENSDART00000102646
ras homolog family member H
chr21_+_5915041 0.02 ENSDART00000151370
proline dehydrogenase (oxidase) 1a
chr20_+_15015557 0.02 ENSDART00000039345
myocilin
chr7_-_29571615 0.02 ENSDART00000019140
RAR-related orphan receptor A, paralog b
chr22_-_5323482 0.02 ENSDART00000145785
sphingosine-1-phosphate receptor 4
chr16_+_46410520 0.02 ENSDART00000131072
rapunzel 2
chr21_-_28439596 0.02 ENSDART00000089980
ENSDART00000132844
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr8_-_43997538 0.02 ENSDART00000186449
RIMS binding protein 2
chr17_+_15433518 0.02 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr22_+_21255860 0.02 ENSDART00000134893
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr3_+_30968883 0.01 ENSDART00000085736
perforin 1.9
chr24_+_19518570 0.01 ENSDART00000056081
sulfatase 1
chr11_+_38280454 0.01 ENSDART00000171496
si:dkey-166c18.1
chr9_+_17984358 0.01 ENSDART00000192399
A kinase (PRKA) anchor protein 11
chr8_+_36803415 0.01 ENSDART00000111680
IQ motif and Sec7 domain 2b
chr16_+_26439939 0.01 ENSDART00000143073
tripartite motif containing 35-28
chr7_-_7810348 0.01 ENSDART00000171984
chemokine (C-X-C motif) ligand 19
chr10_-_9086716 0.01 ENSDART00000140095
ADP-ribosylation factor-like 15b
chr15_+_29662401 0.01 ENSDART00000135540
nuclear receptor interacting protein 1a
chr21_-_21096437 0.01 ENSDART00000186552
ankyrin 1, erythrocytic b
chr6_-_40651944 0.00 ENSDART00000187423
peptidylprolyl isomerase (cyclophilin)-like 1
chr12_+_18543783 0.00 ENSDART00000148326
ENSDART00000134530
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr2_-_5505094 0.00 ENSDART00000145035
S-antigen; retina and pineal gland (arrestin) a
chr9_-_44939104 0.00 ENSDART00000192903
villin 1
chr11_+_30058139 0.00 ENSDART00000112254
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr25_-_27564205 0.00 ENSDART00000157319
hyaluronoglucosaminidase 4
chr1_+_11736420 0.00 ENSDART00000140329
carbohydrate (chondroitin 4) sulfotransferase 12b
chr2_+_38804223 0.00 ENSDART00000147939
capping protein regulator and myosin 1 linker 3

Network of associatons between targets according to the STRING database.

First level regulatory network of bcl11aa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.3 GO:1900181 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.1 0.4 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 0.6 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.2 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.2 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.9 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.0 GO:0042148 strand invasion(GO:0042148)
0.0 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.3 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway