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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for bach1a+bach1b+bach2a+bach2b

Z-value: 0.64

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Transcription factors associated with bach1a+bach1b+bach2a+bach2b

Gene Symbol Gene ID Gene Info
ENSDARG00000002196 BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
ENSDARG00000004074 BTB and CNC homology 1, basic leucine zipper transcription factor 2b
ENSDARG00000036569 BTB and CNC homology 1, basic leucine zipper transcription factor 2a
ENSDARG00000062553 BTB and CNC homology 1, basic leucine zipper transcription factor 1 a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bach1adr11_v1_chr15_-_8191992_81919920.904.6e-07Click!
bach2adr11_v1_chr17_+_15674052_156740520.863.8e-06Click!
bach2bdr11_v1_chr20_-_24122881_241228810.822.5e-05Click!
bach1bdr11_v1_chr10_+_25369254_25369254-0.437.8e-02Click!

Activity profile of bach1a+bach1b+bach2a+bach2b motif

Sorted Z-values of bach1a+bach1b+bach2a+bach2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_33366188 1.59 ENSDART00000074161
solute carrier family 4 (anion exchanger), member 2b
chr16_-_24832038 1.54 ENSDART00000153731
si:dkey-79d12.5
chr16_+_23403602 1.47 ENSDART00000159848
S100 calcium binding protein W
chr1_+_46598764 1.29 ENSDART00000053240
calcium binding protein 39-like
chr7_+_26649319 1.27 ENSDART00000173823
ENSDART00000101053
tumor protein p53 inducible protein 11a
chr10_-_32877348 1.20 ENSDART00000018977
ENSDART00000133421
RAB guanine nucleotide exchange factor (GEF) 1
chr24_-_21973365 1.13 ENSDART00000081204
ENSDART00000030592
acyl-CoA thioesterase 9, tandem duplicate 1
chr5_+_44804791 1.08 ENSDART00000122288
cathepsin La
chr1_+_46598502 1.00 ENSDART00000132861
calcium binding protein 39-like
chr11_+_37638873 1.00 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
SH2 domain containing 5
chr19_+_37120491 1.00 ENSDART00000032341
penta-EF-hand domain containing 1
chr5_+_44805028 0.96 ENSDART00000141198
cathepsin La
chr5_+_44805269 0.94 ENSDART00000136965
cathepsin La
chr8_+_8671229 0.89 ENSDART00000131963
ubiquitin specific peptidase 11
chr2_-_23391266 0.88 ENSDART00000159048
influenza virus NS1A binding protein b
chr21_+_25765734 0.84 ENSDART00000021664
claudin b
chr18_+_3169579 0.83 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
p21 protein (Cdc42/Rac)-activated kinase 1
chr18_+_3243292 0.83 ENSDART00000166580
p21 protein (Cdc42/Rac)-activated kinase 1
chr23_+_2728095 0.82 ENSDART00000066086
zgc:114123
chr5_-_49951106 0.81 ENSDART00000135954
family with sequence similarity 172, member A
chr11_+_45219558 0.81 ENSDART00000167828
transmembrane channel-like 6b
chr5_-_42180205 0.79 ENSDART00000145247
family with sequence similarity 222, member Ba
chr16_+_27543893 0.79 ENSDART00000182421
si:ch211-197h24.6
chr22_+_17399124 0.78 ENSDART00000145769
RAB GTPase activating protein 1-like
chr21_+_13233377 0.76 ENSDART00000142569
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr5_+_9037650 0.76 ENSDART00000158226
si:ch211-155m12.1
chr15_+_25489406 0.76 ENSDART00000162482
zgc:152863
chr19_+_551963 0.75 ENSDART00000110495
A kinase (PRKA) anchor protein 9
chr12_-_3077395 0.75 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_+_51713076 0.74 ENSDART00000146281
RIPOR family member 3
chr16_+_13818743 0.73 ENSDART00000090191
folliculin
chr3_+_35498119 0.71 ENSDART00000178963
trinucleotide repeat containing 6a
chr15_-_31177324 0.70 ENSDART00000008854
WD repeat and SOCS box containing 1
chr2_+_9821757 0.70 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr21_+_37477001 0.70 ENSDART00000114778
angiomotin
chr17_+_19626479 0.70 ENSDART00000044993
ENSDART00000131863
regulator of G protein signaling 7a
chr12_-_27212596 0.69 ENSDART00000153101
proteasome activator subunit 3
chr16_+_13818500 0.69 ENSDART00000135245
folliculin
chr9_+_28140089 0.68 ENSDART00000046880
pleckstrin homology domain containing, family M, member 3
chr12_-_17147473 0.68 ENSDART00000106035
STAM binding protein-like 1
chr17_+_32623931 0.67 ENSDART00000144217
cathepsin Ba
chr19_+_26072624 0.67 ENSDART00000147627
jumonji, AT rich interactive domain 2b
chr18_+_15841449 0.66 ENSDART00000141800
ENSDART00000091349
early endosome antigen 1
chr19_-_31035155 0.66 ENSDART00000161882
basic leucine zipper and W2 domains 2
chr15_+_17343319 0.64 ENSDART00000018461
vacuole membrane protein 1
chr19_-_5805923 0.62 ENSDART00000134340
si:ch211-264f5.8
chr2_+_15100742 0.62 ENSDART00000027171
coagulation factor IIIb
chr23_+_24501918 0.61 ENSDART00000078824
SUZ RNA binding domain containing 1
chr22_-_6562618 0.61 ENSDART00000106100
zgc:171490
chr2_-_26642831 0.60 ENSDART00000132854
ENSDART00000087714
ENSDART00000132651
U2 snRNP-associated SURP domain containing
chr11_-_11965033 0.59 ENSDART00000193683
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr13_+_7575563 0.59 ENSDART00000146592
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr12_-_35386910 0.59 ENSDART00000153453
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr20_-_34069956 0.58 ENSDART00000017941
translocated promoter region b, nuclear basket protein
chr19_-_31035325 0.57 ENSDART00000147504
basic leucine zipper and W2 domains 2
chr4_-_4535189 0.57 ENSDART00000057519
zgc:194209
chr11_-_39118882 0.57 ENSDART00000113185
ENSDART00000156526
adaptor-related protein complex 5, beta 1 subunit
chr9_+_41024973 0.56 ENSDART00000014660
ENSDART00000144467
ORMDL sphingolipid biosynthesis regulator 1
chr25_+_14697247 0.56 ENSDART00000180747
metallophosphoesterase domain containing 2b
chr13_+_7241170 0.56 ENSDART00000109434
apoptosis-inducing factor, mitochondrion-associated, 2
chr3_+_19687217 0.56 ENSDART00000141937
tousled-like kinase 2
chr14_-_36763302 0.55 ENSDART00000074786
cathepsin O
chr25_+_18583877 0.55 ENSDART00000148741
MET proto-oncogene, receptor tyrosine kinase
chr20_+_42537768 0.55 ENSDART00000134066
ENSDART00000153434
si:dkeyp-93d12.1
chr5_+_35786141 0.54 ENSDART00000022043
ENSDART00000127383
StAR-related lipid transfer (START) domain containing 8
chr4_+_25181572 0.53 ENSDART00000078529
ENSDART00000136643
Kin17 DNA and RNA binding protein
chr5_+_34549845 0.51 ENSDART00000139317
allograft inflammatory factor 1-like
chr4_-_1801519 0.51 ENSDART00000188604
ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr14_-_493029 0.49 ENSDART00000115093
zgc:172215
chr12_-_27212880 0.49 ENSDART00000002835
proteasome activator subunit 3
chr15_+_40188076 0.48 ENSDART00000063779
EF-hand domain family, member D1
chr24_-_5691956 0.48 ENSDART00000189112
deleted in autism 1b
chr10_+_32050906 0.48 ENSDART00000137373
si:ch211-266i6.3
chr19_+_48359259 0.47 ENSDART00000167353
shugoshin 1
chr24_-_31090948 0.47 ENSDART00000176799
holocytochrome c synthase b
chr2_+_37837249 0.46 ENSDART00000113337
poly (ADP-ribose) polymerase 2
chr18_-_37355666 0.46 ENSDART00000098914
Yes-associated protein 1
chr23_+_45200481 0.45 ENSDART00000004357
ENSDART00000111126
ENSDART00000193560
ENSDART00000190476
PC4 and SFRS1 interacting protein 1b
chr4_+_5317483 0.45 ENSDART00000150366
si:ch211-214j24.10
chr24_-_21973163 0.45 ENSDART00000131406
acyl-CoA thioesterase 9, tandem duplicate 1
chr23_+_45339684 0.45 ENSDART00000149410
ENSDART00000102441
PC4 and SFRS1 interacting protein 1b
chr2_+_9822319 0.43 ENSDART00000144078
ENSDART00000144371
annexin A13, like
chr7_-_29723761 0.43 ENSDART00000173560
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr2_-_39759059 0.42 ENSDART00000007333
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr7_+_34549198 0.42 ENSDART00000173784
formin homology 2 domain containing 1
chr14_+_28464736 0.42 ENSDART00000019003
proteasome 26S subunit, non-ATPase 10
chr6_-_35309661 0.42 ENSDART00000114960
nitric oxide synthase 1 (neuronal) adaptor protein a
chr8_-_34402839 0.40 ENSDART00000180173
ENSDART00000191588
ENSDART00000186376
GTPase activating protein and VPS9 domains 1
chr25_-_22187397 0.40 ENSDART00000123211
ENSDART00000139110
plakophilin 3a
chr15_+_24704798 0.40 ENSDART00000192470
si:dkey-151p21.7
chr13_+_2357637 0.40 ENSDART00000017148
glutamate-cysteine ligase, catalytic subunit
chr16_+_46410520 0.40 ENSDART00000131072
rapunzel 2
chr22_+_26600834 0.39 ENSDART00000157411
adenylate cyclase 9
chr3_+_17616201 0.38 ENSDART00000156775
RAB5C, member RAS oncogene family
chr3_+_46762703 0.38 ENSDART00000133283
protein kinase C substrate 80K-H
chr22_-_3595439 0.37 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr7_+_34549377 0.37 ENSDART00000191814
formin homology 2 domain containing 1
chr3_-_24205339 0.37 ENSDART00000157135
si:dkey-110g7.8
chr1_+_47165842 0.36 ENSDART00000053152
ENSDART00000167051
carbonyl reductase 1
chr7_-_5487593 0.36 ENSDART00000136594
Rho guanine nucleotide exchange factor (GEF) 11
chr25_+_10410620 0.35 ENSDART00000151886
ets homologous factor
chr21_+_10866421 0.34 ENSDART00000137858
alpha-kinase 2
chr9_+_7030016 0.34 ENSDART00000148047
ENSDART00000148181
inositol polyphosphate-4-phosphatase type I Aa
chr5_-_20678300 0.34 ENSDART00000088639
WSC domain containing 2
chr5_+_20035284 0.34 ENSDART00000191808
small G protein signaling modulator 1a
chr20_-_16548912 0.33 ENSDART00000137601
checkpoint suppressor 1
chr5_-_42123794 0.33 ENSDART00000051135
ER membrane protein complex subunit 6
chr11_+_19370717 0.33 ENSDART00000165906
prickle homolog 2b
chr1_+_41690402 0.32 ENSDART00000177298
F-box protein 41
chr22_+_31023205 0.31 ENSDART00000111561
zmp:0000000735
chr11_+_807153 0.30 ENSDART00000173289
vestigial-like family member 4b
chr8_-_11170114 0.30 ENSDART00000133532
si:ch211-204d2.4
chr21_+_6328801 0.29 ENSDART00000163577
formin binding protein 1b
chr15_-_43978141 0.28 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr18_+_44849809 0.27 ENSDART00000097328
ADP-ribosylation factor GTPase activating protein 2
chr10_-_13239367 0.27 ENSDART00000001253
si:busm1-57f23.1
chr23_-_4705110 0.27 ENSDART00000144536
ENSDART00000129050
ENSDART00000136399
CCHC-type zinc finger, nucleic acid binding protein a
chr7_-_19638319 0.26 ENSDART00000163686
si:ch211-212k18.4
chr24_+_80653 0.26 ENSDART00000158473
ENSDART00000129135
reversion-inducing-cysteine-rich protein with kazal motifs
chr18_+_618005 0.24 ENSDART00000189667
protogenin homolog a (Gallus gallus)
chr11_-_14102131 0.24 ENSDART00000085158
ENSDART00000191962
transmembrane protein 259
chr6_+_56147812 0.23 ENSDART00000150219
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr2_+_47944967 0.23 ENSDART00000135584
finTRIM family, member 19
chr20_-_21994901 0.22 ENSDART00000004984
dishevelled associated activator of morphogenesis 1b
chr23_-_4704938 0.22 ENSDART00000067293
CCHC-type zinc finger, nucleic acid binding protein a
chr21_-_30254185 0.21 ENSDART00000101054
DnaJ (Hsp40) homolog, subfamily C, member 18
chr14_+_34486629 0.21 ENSDART00000131861
thymosin beta 2
chr7_-_5396154 0.21 ENSDART00000172980
Rho guanine nucleotide exchange factor (GEF) 11
chr9_-_22057658 0.20 ENSDART00000101944
crystallin, gamma MX, like 1
chr20_-_16849306 0.19 ENSDART00000131395
ENSDART00000027582
breast cancer metastasis-suppressor 1-like b
chr7_+_38680034 0.19 ENSDART00000171691
ENSDART00000007913
proteasome 26S subunit, ATPase 3
chr17_+_58211 0.18 ENSDART00000157642
si:ch1073-209e23.1
chr18_-_15155962 0.18 ENSDART00000111333
mitochondrial transcription termination factor 2
chr7_+_7696665 0.18 ENSDART00000091099
INO80 complex subunit B
chr15_-_36727462 0.17 ENSDART00000085971
nephrosis 1, congenital, Finnish type (nephrin)
chr20_-_34767472 0.16 ENSDART00000186710
progestin and adipoQ receptor family member VIII
chr11_+_19370447 0.16 ENSDART00000186154
prickle homolog 2b
chr2_+_36109002 0.15 ENSDART00000158978
T-cell receptor alpha joining 28
chr24_-_24797455 0.15 ENSDART00000138741
phosphodiesterase 7A
chr14_+_30279391 0.14 ENSDART00000172794
fibrinogen-like 1
chr2_+_47945359 0.13 ENSDART00000098054
finTRIM family, member 19
chr3_-_16493528 0.12 ENSDART00000142099
si:ch211-23l10.3
chr11_+_11267829 0.12 ENSDART00000026814
ENSDART00000173346
ENSDART00000151926
protein tyrosine phosphatase type IVA, member 1
chr19_-_7272921 0.12 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
retinoid x receptor, beta a
chr5_-_14564878 0.12 ENSDART00000160511
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr1_-_53750522 0.12 ENSDART00000190755
v-akt murine thymoma viral oncogene homolog 3b
chr4_-_77506362 0.11 ENSDART00000174387
ENSDART00000181181

chr2_-_898899 0.11 ENSDART00000058289
dual specificity phosphatase 22b
chr12_-_29233738 0.10 ENSDART00000153175
si:ch211-214e3.5
chr4_+_43408004 0.09 ENSDART00000150476
si:dkeyp-53e4.2
chr10_+_4235998 0.09 ENSDART00000169328
phospholipid phosphatase related 1
chr5_+_27488975 0.09 ENSDART00000123635
secreted frizzled-related protein 1a
chr8_+_48965767 0.09 ENSDART00000008058
AP2 associated kinase 1a
chr18_+_17537344 0.09 ENSDART00000025782
nucleoporin 93
chr19_-_10395683 0.09 ENSDART00000109488
zgc:194578
chr23_+_7548797 0.09 ENSDART00000006765
transmembrane 9 superfamily protein member 4
chr3_-_51142942 0.09 ENSDART00000160789
si:ch211-148f13.1
chr21_+_25688388 0.09 ENSDART00000125709
bicaudal-D-related protein 2
chr23_-_36441693 0.09 ENSDART00000024354
cysteine sulfinic acid decarboxylase
chr11_+_11267493 0.09 ENSDART00000148425
protein tyrosine phosphatase type IVA, member 1
chr25_+_32474031 0.08 ENSDART00000152124
sulfide quinone oxidoreductase
chr5_-_30615901 0.08 ENSDART00000147769
si:ch211-117m20.5
chr5_+_42064144 0.08 ENSDART00000035235
si:ch211-202a12.4
chr9_-_9705512 0.08 ENSDART00000149021
G protein-coupled receptor 156
chr4_+_49196098 0.07 ENSDART00000150678
si:dkey-40n15.1
chr24_-_23998897 0.07 ENSDART00000130053
zmp:0000000991
chr8_+_48966165 0.07 ENSDART00000165425
AP2 associated kinase 1a
chr6_-_35439406 0.06 ENSDART00000073784
regulator of G protein signaling 5a
chr19_+_4139065 0.06 ENSDART00000172524
si:dkey-218f9.10
chr8_+_39511932 0.06 ENSDART00000113511
leucine zipper, putative tumor suppressor 1
chr23_+_17522867 0.06 ENSDART00000002714
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr7_+_34786591 0.06 ENSDART00000173700
si:dkey-148a17.5
chr24_+_30215475 0.06 ENSDART00000164717
si:ch73-358j7.2
chr17_-_45247332 0.05 ENSDART00000016815
tau tubulin kinase 2a
chr13_+_1430094 0.05 ENSDART00000169888
si:ch211-165e15.1
chr4_+_7822773 0.05 ENSDART00000171391
si:ch1073-67j19.2
chr17_-_19626357 0.05 ENSDART00000011432
receptor accessory protein 3a
chr9_+_22388686 0.04 ENSDART00000182731
ENSDART00000181462
diacylglycerol kinase, gamma
chr15_-_38129845 0.04 ENSDART00000057095
si:dkey-24p1.1
chr22_-_26595027 0.04 ENSDART00000184162

chr18_-_13360106 0.04 ENSDART00000091512
c-Maf inducing protein
chr3_-_584950 0.04 ENSDART00000164752
diverse immunoglobulin domain-containing protein 1.1
chr15_+_28989573 0.04 ENSDART00000076648
CAP-GLY domain containing linker protein 3
chr3_-_34816893 0.04 ENSDART00000084448
ENSDART00000154696
proteasome 26S subunit, non-ATPase 11a
chr4_+_54899568 0.04 ENSDART00000162786
si:dkey-56m15.8
chr3_-_48259289 0.04 ENSDART00000160717
zinc finger protein 750
chr10_+_22771176 0.04 ENSDART00000192046
transmembrane protein 88 a
chr8_-_44463985 0.03 ENSDART00000016845
major histocompatibility complex class I LBA
chr16_+_48714048 0.03 ENSDART00000148709
ENSDART00000150121
bromodomain containing 2b
chr22_+_8800432 0.03 ENSDART00000139940
si:dkey-182g1.6
chr21_+_26620867 0.03 ENSDART00000176008
estrogen-related receptor alpha
chr10_-_20445549 0.03 ENSDART00000064613
lysyl oxidase-like 2a
chr23_-_28239750 0.03 ENSDART00000003548
zinc finger protein 385A
chr20_-_47270519 0.03 ENSDART00000153329
si:dkeyp-104f11.8
chr6_+_10534752 0.02 ENSDART00000090874
potassium channel, voltage gated eag related subfamily H, member 7
chr4_-_71913556 0.02 ENSDART00000167608
si:dkey-92c21.1
chr2_+_25278107 0.02 ENSDART00000131977
protein phosphatase 2, regulatory subunit B'', alpha
chr4_-_64604842 0.02 ENSDART00000169862
zinc finger protein 1099
chr4_+_69624049 0.02 ENSDART00000170052
zinc finger protein 1030
chr6_-_21534301 0.02 ENSDART00000126186
proteasome 26S subunit, non-ATPase 12

Network of associatons between targets according to the STRING database.

First level regulatory network of bach1a+bach1b+bach2a+bach2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0003232 bulbus arteriosus development(GO:0003232)
0.3 0.8 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.2 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 1.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.4 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.6 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.5 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.8 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 1.0 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.8 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.5 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.5 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 0.5 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.3 GO:0006901 vesicle coating(GO:0006901)
0.1 0.7 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.3 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.1 0.6 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.8 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.2 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.7 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.6 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.4 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 1.2 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.5 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.6 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.6 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.8 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.6 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 1.6 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.5 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.6 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.5 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:1901296 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:0017177 glucosidase II complex(GO:0017177)
0.1 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 5.6 GO:0005764 lysosome(GO:0005764)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.5 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 1.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.6 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.8 GO:0035197 siRNA binding(GO:0035197)
0.1 0.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.5 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.5 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 1.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 2.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.7 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.4 GO:0043531 ADP binding(GO:0043531)
0.1 1.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.6 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.3 GO:0032977 membrane insertase activity(GO:0032977)
0.0 4.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 1.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 2.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)