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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for atf2+atf7a+atf7b_creb5a+creb5b

Z-value: 0.88

Motif logo

Transcription factors associated with atf2+atf7a+atf7b_creb5a+creb5b

Gene Symbol Gene ID Gene Info
ENSDARG00000011298 activating transcription factor 7a
ENSDARG00000023903 activating transcription factor 2
ENSDARG00000055481 activating transcription factor 7b
ENSDARG00000114492 activating transcription factor 7b
ENSDARG00000115171 activating transcription factor 7b
ENSDARG00000070536 cAMP responsive element binding protein 5b
ENSDARG00000099002 cAMP responsive element binding protein 5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf7bdr11_v1_chr6_-_39631164_396311810.977.4e-12Click!
creb5bdr11_v1_chr16_-_20707742_20707742-0.599.6e-03Click!
creb5adr11_v1_chr19_-_19505167_19505167-0.561.5e-02Click!
atf7adr11_v1_chr23_-_27479558_274795580.503.6e-02Click!
atf2dr11_v1_chr9_+_2343096_2343172-0.292.5e-01Click!

Activity profile of atf2+atf7a+atf7b_creb5a+creb5b motif

Sorted Z-values of atf2+atf7a+atf7b_creb5a+creb5b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_35603637 8.12 ENSDART00000147278
polo-like kinase 3 (Drosophila)
chr16_-_29387215 3.85 ENSDART00000148787
S100 calcium binding protein A1
chr11_-_44801968 3.47 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr2_+_12255568 3.33 ENSDART00000184164
ENSDART00000013454
phosphoribosyl transferase domain containing 1
chr7_-_51773166 3.25 ENSDART00000054591
bone morphogenetic protein 15
chr25_-_6447835 2.89 ENSDART00000012820
snurportin 1
chr14_+_30285613 2.89 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr24_-_19718077 2.69 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr25_-_6448050 2.60 ENSDART00000180616
snurportin 1
chr8_-_410199 2.39 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
tripartite motif containing 36
chr18_+_8917766 2.36 ENSDART00000145226
si:ch211-233h19.2
chr8_-_410728 2.33 ENSDART00000151255
tripartite motif containing 36
chr19_-_25772980 2.18 ENSDART00000052393
par-6 family cell polarity regulator gamma b
chr17_-_24866727 2.16 ENSDART00000027957
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr17_+_25187226 2.14 ENSDART00000148431
CLN8, transmembrane ER and ERGIC protein
chr6_+_112579 2.12 ENSDART00000034505
adaptor-related protein complex 1, mu 2 subunit
chr17_-_24866964 2.07 ENSDART00000190601
ENSDART00000192547
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr15_+_20239141 1.90 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr12_-_17863467 1.90 ENSDART00000042006
BAI1-associated protein 2-like 1a
chr8_+_11687586 1.84 ENSDART00000146241
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr12_-_35505610 1.80 ENSDART00000105518
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr8_-_25846188 1.77 ENSDART00000128829
EF-hand domain family, member D2
chr2_-_10386738 1.73 ENSDART00000016369
wntless Wnt ligand secretion mediator
chr7_-_69429561 1.73 ENSDART00000127351
ataxin 1-like
chr8_-_13678415 1.67 ENSDART00000134153
ENSDART00000143331
si:dkey-258f14.3
chr18_-_8380090 1.66 ENSDART00000141581
ENSDART00000081143
selenophosphate synthetase 1
chr4_-_16628801 1.66 ENSDART00000040708
ENSDART00000064009
caprin family member 2
chr12_+_46869271 1.63 ENSDART00000166560
4-hydroxyphenylpyruvate dioxygenase-like
chr25_-_34845302 1.60 ENSDART00000039485
GABA(A) receptor-associated protein like 2
chr1_+_10305611 1.59 ENSDART00000043881
zgc:77880
chr23_+_10805188 1.59 ENSDART00000035693
protein phosphatase 4, regulatory subunit 2a
chr17_+_15674052 1.59 ENSDART00000156726
BTB and CNC homology 1, basic leucine zipper transcription factor 2a
chr4_+_76304911 1.59 ENSDART00000172734
ENSDART00000161850
si:ch73-389k6.1
chr10_+_26990095 1.58 ENSDART00000064111
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b
chr12_-_41759686 1.56 ENSDART00000172175
ENSDART00000165152
protein phosphatase 2, regulatory subunit B, delta
chr10_-_6588793 1.55 ENSDART00000163788
chromodomain helicase DNA binding protein 1
chr7_-_26532089 1.54 ENSDART00000121698
SUMO1/sentrin/SMT3 specific peptidase 3b
chr9_+_34148714 1.54 ENSDART00000078051
G protein-coupled receptor 161
chr11_+_42474694 1.52 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
chr15_-_20412286 1.47 ENSDART00000008589
calcineurin-like EF-hand protein 2
chr14_+_1170968 1.47 ENSDART00000125203
ENSDART00000193575
HOP homeobox
chr9_-_6502491 1.45 ENSDART00000102672
NCK adaptor protein 2a
chr6_-_29049022 1.43 ENSDART00000190309
ecotropic viral integration site 5b
chr3_-_49514874 1.41 ENSDART00000167179
anti-silencing function 1Ba histone chaperone
chr19_+_42227400 1.37 ENSDART00000131574
ENSDART00000135436
jumping translocation breakpoint
chr3_+_53116172 1.32 ENSDART00000115117
bromodomain containing 4
chr23_-_29357764 1.31 ENSDART00000156512
si:ch211-129o18.4
chr7_+_70338270 1.30 ENSDART00000065234
glucosidase, beta, acid 3 (gene/pseudogene)
chr9_-_28939181 1.29 ENSDART00000101276
ENSDART00000135334
erythrocyte membrane protein band 4.1 like 5
chr12_+_33320884 1.25 ENSDART00000188988
casein kinase 1, delta b
chr14_+_30413312 1.24 ENSDART00000186864
CCR4-NOT transcription complex, subunit 7
chr5_+_30089715 1.24 ENSDART00000078114
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr15_+_34963316 1.23 ENSDART00000153840
si:ch73-95l15.5
chr8_+_48965767 1.22 ENSDART00000008058
AP2 associated kinase 1a
chr23_-_27505825 1.22 ENSDART00000137229
ENSDART00000013797
ankyrin repeat and SOCS box containing 8
chr6_+_21227621 1.22 ENSDART00000193583
protein kinase C, alpha
chr2_+_9560740 1.22 ENSDART00000003465
GIPC PDZ domain containing family, member 2
chr20_-_3319642 1.21 ENSDART00000186743
ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr4_-_12930086 1.21 ENSDART00000013604
LEM domain containing 3
chr15_-_1765098 1.18 ENSDART00000149980
ENSDART00000093074
BUD23, rRNA methyltransferase and ribosome maturation factor
chr23_+_34990693 1.17 ENSDART00000013449
si:ch211-236h17.3
chr16_-_9869056 1.16 ENSDART00000149312
neurocalcin delta a
chr23_+_29358188 1.15 ENSDART00000189242
TAR DNA binding protein, like
chr22_-_38934989 1.14 ENSDART00000008365
nuclear cap binding protein subunit 2
chr23_-_25686894 1.14 ENSDART00000181420
ENSDART00000088208
low density lipoprotein receptor-related protein 1Ab
chr2_-_17114852 1.13 ENSDART00000006549
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr5_+_26921033 1.10 ENSDART00000051483
TM2 domain containing 2
chr25_+_3104959 1.10 ENSDART00000167130
RAB3A interacting protein (rabin3)-like 1
chr18_+_8912113 1.10 ENSDART00000147467
transmembrane protein 243, mitochondrial a
chr7_-_33868903 1.10 ENSDART00000173500
ENSDART00000178746
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr13_-_49444636 1.09 ENSDART00000136991
interferon regulatory factor 2 binding protein 2a
chr5_+_22133153 1.08 ENSDART00000016214
moesin a
chr9_+_25840720 1.08 ENSDART00000024572
glycosyltransferase-like domain containing 1
chr2_-_17115256 1.08 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr5_-_30145939 1.06 ENSDART00000086795
zinc finger and BTB domain containing 44
chr25_-_37084032 1.06 ENSDART00000025494
hypoxanthine phosphoribosyltransferase 1, like
chr5_-_37959874 1.05 ENSDART00000031719
myelin protein zero-like 2b
chr19_+_42660158 1.04 ENSDART00000018328
F-box and leucine-rich repeat protein 2
chr4_-_73488406 1.04 ENSDART00000115002
si:ch73-266f23.1
chr23_-_43424510 1.03 ENSDART00000055564
regulation of nuclear pre-mRNA domain containing 1B
chr4_+_73051901 1.03 ENSDART00000174219
zgc:152938
chr22_+_1940595 1.03 ENSDART00000163506
zinc finger protein 1167
chr13_+_51710725 1.02 ENSDART00000163741
PWWP domain containing 2B
chr16_+_14201401 1.01 ENSDART00000113679
death associated protein 3
chr23_-_27506161 1.00 ENSDART00000145007
ankyrin repeat and SOCS box containing 8
chr2_-_4032732 1.00 ENSDART00000158335
RAB18B, member RAS oncogene family
chr15_+_807897 1.00 ENSDART00000153549
si:dkey-7i4.8
chr23_-_35396845 0.99 ENSDART00000142038
ENSDART00000049373
ENSDART00000181978
ENSDART00000171357
cap methyltransferase 1
chr19_+_26923110 0.97 ENSDART00000149988
negative elongation factor complex member E
chr18_-_20444296 0.96 ENSDART00000132993
kinesin family member 23
chr5_-_19444930 0.95 ENSDART00000136259
ENSDART00000188499
potassium channel tetramerization domain containing 10
chr23_-_1571682 0.94 ENSDART00000013635
F-box protein 30b
chr17_+_23554932 0.94 ENSDART00000135814
pantothenate kinase 1a
chr15_-_43995028 0.93 ENSDART00000172485
ENSDART00000186320
NLR family, CARD domain containing 3-like
chr7_-_19999152 0.93 ENSDART00000173881
ENSDART00000100798
thyroid hormone receptor interactor 6
chr20_+_39223235 0.93 ENSDART00000132132
RALBP1 associated Eps domain containing 1
chr18_+_8912536 0.92 ENSDART00000134827
ENSDART00000061904
transmembrane protein 243, mitochondrial a
chr23_-_17509656 0.91 ENSDART00000148423
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr16_-_41667101 0.91 ENSDART00000084528
ATPase secretory pathway Ca2+ transporting 1
chr24_+_26329018 0.90 ENSDART00000145752
myoneurin
chr8_-_38317914 0.90 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr21_-_25395223 0.90 ENSDART00000016219
protein phosphatase methylesterase 1
chr17_-_8674208 0.90 ENSDART00000149201
C-terminal binding protein 2a
chr24_-_18876877 0.90 ENSDART00000186269
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr7_+_28612671 0.88 ENSDART00000019991
solute carrier family 7, member 6 opposite strand
chr4_+_77141970 0.88 ENSDART00000174209
si:dkey-172k15.11
chr4_+_76466751 0.87 ENSDART00000164709
zgc:153116
chr16_+_25137483 0.84 ENSDART00000155666
zinc finger protein 576, tandem duplicate 1
chr23_+_4709607 0.83 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr1_-_23595779 0.83 ENSDART00000134860
ENSDART00000138852
ligand dependent nuclear receptor corepressor-like
chr11_+_25296366 0.82 ENSDART00000065949
DNA topoisomerase I, like
chr7_+_34549198 0.82 ENSDART00000173784
formin homology 2 domain containing 1
chr2_-_43739559 0.81 ENSDART00000138947
kinesin family member 5B, a
chr7_-_19998723 0.81 ENSDART00000173458
thyroid hormone receptor interactor 6
chr7_+_7552008 0.81 ENSDART00000173018
ENSDART00000049311
chloride channel 3
chr2_-_37477654 0.80 ENSDART00000193921
death-associated protein kinase 3
chr17_-_8673567 0.80 ENSDART00000192714
ENSDART00000012546
C-terminal binding protein 2a
chr13_-_17464362 0.80 ENSDART00000145499
leucine rich melanocyte differentiation associated
chr24_+_26328787 0.80 ENSDART00000003884
myoneurin
chr24_-_37326236 0.80 ENSDART00000003789
3-phosphoinositide dependent protein kinase 1b
chr2_-_56635744 0.79 ENSDART00000167790
ENSDART00000168160
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b
chr20_-_37933237 0.79 ENSDART00000142567
ENSDART00000036371
ENSDART00000061445
angel homolog 2 (Drosophila)
chr21_-_45382112 0.77 ENSDART00000151029
ENSDART00000151335
ENSDART00000151687
ENSDART00000075438
CDKN2A interacting protein N-terminal like
chr19_+_26923274 0.77 ENSDART00000148439
ENSDART00000148877
negative elongation factor complex member E
chr8_-_1267247 0.76 ENSDART00000150064
cell division cycle 14B
chr7_+_34549377 0.76 ENSDART00000191814
formin homology 2 domain containing 1
chr21_+_19547806 0.76 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
retinoic acid induced 14
chr4_+_73651053 0.75 ENSDART00000150532
ENSDART00000172536
zinc finger protein 989
chr25_-_25646806 0.75 ENSDART00000089066
TBC1 domain family, member 2B
chr23_+_1661743 0.75 ENSDART00000044776
syntaxin binding protein 3
chr21_-_23307653 0.75 ENSDART00000140284
ENSDART00000134103
zinc finger and BTB domain containing 16a
chr14_+_30413758 0.74 ENSDART00000092953
CCR4-NOT transcription complex, subunit 7
chr10_+_28306749 0.74 ENSDART00000142016
peptidyl-tRNA hydrolase 2
chr12_+_33320504 0.74 ENSDART00000021491
casein kinase 1, delta b
chr6_+_27667359 0.73 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr6_+_13232934 0.72 ENSDART00000089725
INO80 complex subunit Db
chr4_-_1839192 0.72 ENSDART00000003790
PWP1 homolog (S. cerevisiae)
chr23_-_29667544 0.71 ENSDART00000059339
calsyntenin 1
chr5_+_1965296 0.71 ENSDART00000156224
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr24_-_18877118 0.70 ENSDART00000092783
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr24_-_16979728 0.70 ENSDART00000005331
kelch-like family member 15
chr7_+_15659280 0.70 ENSDART00000173414
myocyte enhancer factor 2ab
chr2_-_43739740 0.69 ENSDART00000113849
kinesin family member 5B, a
chr8_-_31417139 0.69 ENSDART00000180204
zinc finger protein 131
chr22_-_718615 0.69 ENSDART00000149320
ADP-ribosylation factor-like 8A
chr20_-_34801181 0.68 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr2_-_55779927 0.68 ENSDART00000168579

chr13_-_25774183 0.68 ENSDART00000046981
PDZ and LIM domain 1 (elfin)
chr16_+_27614989 0.68 ENSDART00000005625
GLI pathogenesis-related 2, like
chr14_-_38946808 0.66 ENSDART00000139293
galactosidase, alpha
chr17_-_31212420 0.66 ENSDART00000086511
RNA pseudouridylate synthase domain containing 2
chr6_+_6802582 0.65 ENSDART00000189422
D-tyrosyl-tRNA deacylase 1
chr4_+_9478500 0.65 ENSDART00000030738
lipase maturation factor 2b
chr20_+_23947004 0.65 ENSDART00000144195
caspase 8 associated protein 2
chr4_+_76305357 0.65 ENSDART00000160326
si:ch73-389k6.1
chr3_+_25907266 0.65 ENSDART00000170324
ENSDART00000192633
target of myb1 membrane trafficking protein
chr18_+_14633974 0.65 ENSDART00000133834
VPS9 domain containing 1
chr18_+_27598755 0.65 ENSDART00000193808
CD82 molecule b
chr1_+_19538299 0.64 ENSDART00000109416
structural maintenance of chromosomes 2
chr20_-_44576949 0.64 ENSDART00000148639
UBX domain protein 2A
chr1_+_49878000 0.64 ENSDART00000047876
lymphoid enhancer-binding factor 1
chr23_+_29357790 0.63 ENSDART00000139223
ENSDART00000141928
TAR DNA binding protein, like
chr24_-_37338162 0.63 ENSDART00000056303
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr22_+_38935060 0.62 ENSDART00000183732
ENSDART00000130055
sirtuin 7
chr23_+_23183449 0.62 ENSDART00000132296
kelch-like family member 17
chr9_-_6501924 0.62 ENSDART00000168143
NCK adaptor protein 2a
chr24_+_37338169 0.62 ENSDART00000141771
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr11_-_575786 0.61 ENSDART00000019997
makorin, ring finger protein, 2
chr12_+_36109507 0.60 ENSDART00000175409
mitogen-activated protein kinase kinase 6
chr20_+_36812368 0.60 ENSDART00000062931
ABRA C-terminal like
chr1_-_29061285 0.60 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gem (nuclear organelle) associated protein 8
chr23_-_10722664 0.59 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
forkhead box P1a
chr11_+_24314148 0.58 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr10_+_44903676 0.58 ENSDART00000158553
zgc:114173
chr21_-_36571804 0.58 ENSDART00000138129
WW and C2 domain containing 1
chr22_+_1517318 0.56 ENSDART00000160406
si:ch211-255f4.5
chr5_+_28259655 0.56 ENSDART00000087684
non-SMC condensin I complex, subunit H
chr12_+_38807604 0.56 ENSDART00000155563
ATP-binding cassette, sub-family A (ABC1), member 5
chr22_+_1947494 0.56 ENSDART00000159121
si:dkey-15h8.15
chr1_+_52792439 0.56 ENSDART00000123972
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr13_-_40754499 0.56 ENSDART00000111641
ENSDART00000159255
MORN repeat containing 4
chr5_+_56277866 0.56 ENSDART00000170610
ENSDART00000028854
ENSDART00000148749
apoptosis antagonizing transcription factor
chr14_+_16083818 0.55 ENSDART00000168462
ring finger protein 103
chr8_+_1839695 0.55 ENSDART00000148254
ENSDART00000143473
synaptosomal-associated protein 29
chr4_-_1839352 0.55 ENSDART00000189215
PWP1 homolog (S. cerevisiae)
chr8_+_29742237 0.54 ENSDART00000133955
ENSDART00000020621
mitogen-activated protein kinase 4
chr21_-_44772738 0.54 ENSDART00000026178
kinesin family member 4
chr18_-_12451772 0.53 ENSDART00000175083
si:ch211-1e14.1
chr6_-_25952848 0.53 ENSDART00000076997
ENSDART00000148748
LIM domain only 4b
chr1_-_18592068 0.53 ENSDART00000082063
family with sequence similarity 114, member A1
chr18_+_910992 0.53 ENSDART00000161206
ENSDART00000167229
pyruvate kinase M1/2a
chr17_-_5610514 0.53 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr6_-_14010554 0.52 ENSDART00000004656
zgc:92027
chr14_+_20351 0.52 ENSDART00000051893
syntaxin 18
chr15_+_23443665 0.52 ENSDART00000059369
5-phosphohydroxy-L-lysine phospho-lyase
chr20_+_46699021 0.51 ENSDART00000167398
ENSDART00000029894
WD repeat domain 26b
chr15_-_704408 0.51 ENSDART00000156200
ENSDART00000166404
ENSDART00000131040
zgc:174574
chr10_-_1276046 0.51 ENSDART00000169779
PDZ and LIM domain 5b
chr8_-_13735572 0.51 ENSDART00000139642
si:dkey-258f14.7
chr25_-_12906872 0.50 ENSDART00000165156
ENSDART00000167449
septin 15

Network of associatons between targets according to the STRING database.

First level regulatory network of atf2+atf7a+atf7b_creb5a+creb5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 8.1 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
1.4 5.5 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
1.1 4.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.8 3.3 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.6 1.7 GO:0061355 Wnt protein secretion(GO:0061355)
0.6 1.1 GO:0051030 snRNA transport(GO:0051030)
0.6 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.6 1.7 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.4 1.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.4 1.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 1.1 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.4 1.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 1.3 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.3 1.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 1.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 1.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 5.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 2.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 1.7 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.2 0.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 1.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 1.3 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.7 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.2 1.3 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 1.7 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.2 0.9 GO:0014005 microglia development(GO:0014005)
0.2 2.2 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 0.9 GO:0055071 manganese ion homeostasis(GO:0055071)
0.2 1.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 2.2 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.2 0.5 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.2 1.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 1.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 1.0 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.0 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.6 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.1 0.9 GO:0048532 anatomical structure arrangement(GO:0048532)
0.1 0.6 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 1.8 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.7 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.8 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.5 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.4 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 1.1 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 1.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.6 GO:0032475 otolith formation(GO:0032475)
0.1 0.3 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.1 1.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.3 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.8 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 1.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.5 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.5 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.2 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 2.8 GO:0072114 pronephros morphogenesis(GO:0072114)
0.1 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.3 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.3 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 5.7 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 0.3 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.1 2.7 GO:0030901 midbrain development(GO:0030901)
0.1 0.3 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.8 GO:0006265 DNA topological change(GO:0006265)
0.0 1.6 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.5 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 2.6 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.5 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.2 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 3.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 1.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.8 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 2.2 GO:0055088 lipid homeostasis(GO:0055088)
0.0 1.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.9 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 1.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 1.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0090594 inflammatory response to wounding(GO:0090594)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 1.5 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.0 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.2 GO:0001845 phagolysosome assembly(GO:0001845)
0.0 2.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0034334 cell junction maintenance(GO:0034331) adherens junction maintenance(GO:0034334)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.3 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.5 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0010960 magnesium ion homeostasis(GO:0010960)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.3 1.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.2 1.7 GO:0032021 NELF complex(GO:0032021)
0.2 1.1 GO:0034518 RNA cap binding complex(GO:0034518)
0.2 2.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 5.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 3.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.8 GO:0000796 condensin complex(GO:0000796)
0.1 8.9 GO:0000922 spindle pole(GO:0000922)
0.1 0.6 GO:0016589 NURF complex(GO:0016589)
0.1 0.4 GO:0070209 ASTRA complex(GO:0070209)
0.1 2.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.6 GO:0032797 SMN complex(GO:0032797)
0.1 1.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.3 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 4.6 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 2.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.4 GO:0030496 midbody(GO:0030496)
0.1 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.2 GO:0005657 replication fork(GO:0005657)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.2 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 1.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.3 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.0 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.5 1.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.4 2.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 2.6 GO:0070698 type I activin receptor binding(GO:0070698)
0.4 1.1 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.3 5.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.3 1.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 2.1 GO:0046625 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.2 0.7 GO:0015925 alpha-galactosidase activity(GO:0004557) galactosidase activity(GO:0015925)
0.2 0.7 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.2 1.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 2.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 3.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.4 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 2.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 2.1 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 1.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.6 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.4 GO:0030552 cAMP binding(GO:0030552)
0.1 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 5.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 1.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.2 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0008887 glycerate kinase activity(GO:0008887)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 2.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.5 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.7 GO:0051287 NAD binding(GO:0051287)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 2.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.8 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.8 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 2.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 1.6 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 3.7 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0070330 aromatase activity(GO:0070330)
0.0 0.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 8.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 8.4 PID P73PATHWAY p73 transcription factor network
0.1 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.4 PID AURORA B PATHWAY Aurora B signaling
0.1 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 7.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 6.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 2.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 4.4 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 3.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import