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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for arnt2

Z-value: 1.70

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Transcription factors associated with arnt2

Gene Symbol Gene ID Gene Info
ENSDARG00000103697 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arnt2dr11_v1_chr7_+_10701938_107019380.961.8e-10Click!

Activity profile of arnt2 motif

Sorted Z-values of arnt2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_10152092 5.51 ENSDART00000066053
chromobox homolog 2 (Drosophila Pc class)
chr1_+_49814461 5.03 ENSDART00000132405
lymphoid enhancer-binding factor 1
chr4_+_9279784 4.32 ENSDART00000014897
SLIT-ROBO Rho GTPase activating protein 1b
chr10_-_25217347 4.01 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr3_-_1283247 3.94 ENSDART00000149814
transcription factor 20
chr20_-_48898371 3.86 ENSDART00000170617
5'-3' exoribonuclease 2
chr12_+_38807604 3.77 ENSDART00000155563
ATP-binding cassette, sub-family A (ABC1), member 5
chr2_-_21438492 3.69 ENSDART00000046098
phospholipase C, delta 1b
chr8_-_18899427 3.51 ENSDART00000079840
RAR-related orphan receptor C a
chr5_+_25733774 3.46 ENSDART00000137088
ENSDART00000098467
abhydrolase domain containing 17B
chr10_+_29963518 3.40 ENSDART00000011317
ENSDART00000099964
ENSDART00000182990
ENSDART00000113912
neurotrimin
chr2_-_21820697 3.17 ENSDART00000135230
chromodomain helicase DNA binding protein 7
chr21_-_30082414 3.15 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr15_-_33734105 3.13 ENSDART00000172729
ENSDART00000172045
tRNA methyltransferase 9B
chr11_-_34577034 3.13 ENSDART00000133302
ENSDART00000184367
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr24_-_42072886 3.04 ENSDART00000171389

chr20_-_182841 3.03 ENSDART00000064546
si:ch211-241j12.3
chr6_-_53144336 2.98 ENSDART00000154429
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr23_-_26227805 2.91 ENSDART00000158082

chr22_-_718615 2.89 ENSDART00000149320
ADP-ribosylation factor-like 8A
chr4_-_77561679 2.88 ENSDART00000180809

chr18_-_20608025 2.88 ENSDART00000090156
ENSDART00000151980
BCL2 like 13
chr20_+_27712714 2.87 ENSDART00000008306
zinc finger and BTB domain containing 1
chr22_+_10781894 2.86 ENSDART00000081183
ectodermal-neural cortex 3
chr4_+_2482046 2.84 ENSDART00000103371
zinc finger, DHHC-type containing 17
chr7_+_10701938 2.81 ENSDART00000158162
aryl-hydrocarbon receptor nuclear translocator 2
chr21_-_13856689 2.81 ENSDART00000102197
family with sequence similarity 129, member Ba
chr16_-_34195002 2.79 ENSDART00000054026
regulator of chromosome condensation 1
chr8_+_50190742 2.73 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr23_-_26228077 2.71 ENSDART00000162423

chr13_-_15929402 2.71 ENSDART00000090273
tubulin tyrosine ligase
chr20_+_38543542 2.71 ENSDART00000145254
general transcription factor IIIC, polypeptide 2, beta
chr6_-_53143667 2.66 ENSDART00000079694
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr21_-_4849029 2.64 ENSDART00000168930
ENSDART00000151019
notch 1a
chr14_+_24840669 2.61 ENSDART00000106039
Rho guanine nucleotide exchange factor (GEF) 37
chr3_-_60589292 2.61 ENSDART00000157822
jumonji domain containing 6
chr17_-_12249990 2.60 ENSDART00000177889
ENSDART00000155545
AT hook containing transcription factor 1
chr17_+_19630272 2.59 ENSDART00000104895
regulator of G protein signaling 7a
chr8_+_2642384 2.58 ENSDART00000143242
nuclear apoptosis inducing factor 1
chr7_-_60351876 2.58 ENSDART00000098563
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr17_+_34805897 2.53 ENSDART00000137090
ENSDART00000077626
inhibitor of DNA binding 2a
chr15_-_4616816 2.51 ENSDART00000160191
ENSDART00000161721
ENSDART00000144949
eukaryotic translation initiation factor 4h
chr13_+_33268657 2.50 ENSDART00000002095
transmembrane protein 39B
chr5_-_22130937 2.46 ENSDART00000138606
LAS1-like, ribosome biogenesis factor
chr15_-_16076399 2.46 ENSDART00000135658
ENSDART00000133755
ENSDART00000080413
serine/arginine-rich splicing factor 1a
chr18_-_46684352 2.45 ENSDART00000167520
phosphotyrosine interaction domain containing 1
chr7_-_60351537 2.44 ENSDART00000159875
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr10_+_5268054 2.40 ENSDART00000114491
receptor tyrosine kinase-like orphan receptor 2
chr4_-_15003854 2.38 ENSDART00000134701
ENSDART00000002401
kelch domain containing 10
chr13_-_24826607 2.37 ENSDART00000087786
ENSDART00000186951
STE20-like kinase a
chr16_-_7793457 2.36 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr9_-_34945566 2.36 ENSDART00000131908
ENSDART00000059861
DCN1, defective in cullin neddylation 1, domain containing 2a
chr3_-_25054002 2.36 ENSDART00000086768
E1A binding protein p300 b
chr19_-_30800004 2.31 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
tRNA isopentenyltransferase 1
chr13_-_45022301 2.30 ENSDART00000183589
ENSDART00000125633
ENSDART00000074787
KH domain containing, RNA binding, signal transduction associated 1a
chr22_-_21150845 2.30 ENSDART00000027345
transmembrane protein 59-like
chr1_+_49814942 2.29 ENSDART00000164936
lymphoid enhancer-binding factor 1
chr22_+_25086942 2.27 ENSDART00000061117
ribosome binding protein 1b
chr4_-_12930086 2.27 ENSDART00000013604
LEM domain containing 3
chr2_-_32594777 2.22 ENSDART00000134125
Fas-activated serine/threonine kinase
chr7_+_10701770 2.21 ENSDART00000167323
aryl-hydrocarbon receptor nuclear translocator 2
chr16_+_54641230 2.21 ENSDART00000157641
ENSDART00000159540
F-box protein 43
chr15_-_34865952 2.18 ENSDART00000186868
SH3-binding domain protein 5-like, a
chr15_+_34963316 2.17 ENSDART00000153840
si:ch73-95l15.5
chr14_-_24110707 2.15 ENSDART00000133522
ENSDART00000123152
cytoplasmic polyadenylation element binding protein 4a
chr9_-_12269847 2.14 ENSDART00000136558
ENSDART00000144734
ENSDART00000131766
ENSDART00000032344
nucleoporin 35
chr8_+_23861461 2.14 ENSDART00000037109
SRSF protein kinase 1a
chr10_+_23060391 2.13 ENSDART00000079711
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr19_+_41006975 2.12 ENSDART00000138555
ENSDART00000049842
CAS1 domain containing 1
chr14_+_50918769 2.10 ENSDART00000146918
ring finger protein 44
chr22_+_25086567 2.09 ENSDART00000192114
ENSDART00000177284
ENSDART00000180296
ENSDART00000190384
ribosome binding protein 1b
chr12_-_24832297 2.08 ENSDART00000066317
forkhead box N2b
chr3_+_19665319 2.06 ENSDART00000007857
ENSDART00000193509
methyltransferase like 2A
chr15_-_8856391 2.06 ENSDART00000008273
RAB4B, member RAS oncogene family
chr14_+_8947282 2.04 ENSDART00000047993
ribosomal protein S6 kinase a, like
chr20_+_27713210 2.04 ENSDART00000132222
zinc finger and BTB domain containing 1
chr10_+_8197827 2.03 ENSDART00000026244
Mtr4 exosome RNA helicase
chr1_-_55248496 2.02 ENSDART00000098615
nanos homolog 3
chr17_+_19630068 2.01 ENSDART00000182619
regulator of G protein signaling 7a
chr1_-_40519340 1.99 ENSDART00000114659
mastermind-like transcriptional coactivator 3
chr5_+_27583445 1.98 ENSDART00000136488
zinc finger, matrin-type 4a
chr19_-_43757568 1.98 ENSDART00000058491
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr12_-_48943467 1.97 ENSDART00000191829

chr1_-_53685090 1.97 ENSDART00000162751
exportin 1 (CRM1 homolog, yeast) a
chr25_-_34845302 1.97 ENSDART00000039485
GABA(A) receptor-associated protein like 2
chr15_-_34866219 1.96 ENSDART00000099723
SH3-binding domain protein 5-like, a
chr18_-_8380090 1.96 ENSDART00000141581
ENSDART00000081143
selenophosphate synthetase 1
chr3_-_34136368 1.96 ENSDART00000136900
ENSDART00000186125
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr13_-_45022527 1.94 ENSDART00000159021
KH domain containing, RNA binding, signal transduction associated 1a
chr11_+_14321113 1.94 ENSDART00000039822
ENSDART00000137347
ENSDART00000132997
polypyrimidine tract binding protein 1b
chr15_+_30126971 1.94 ENSDART00000100214
nuclear fragile X mental retardation protein interacting protein 2
chr13_-_15928934 1.89 ENSDART00000142732
tubulin tyrosine ligase
chr8_-_19266325 1.89 ENSDART00000036148
ENSDART00000137994
zgc:77486
chr6_+_38626684 1.88 ENSDART00000086533
ATPase phospholipid transporting 10A
chr2_+_38271392 1.87 ENSDART00000042100
homeobox and leucine zipper encoding a
chr10_+_11260170 1.85 ENSDART00000155742
hydroxysteroid dehydrogenase like 2
chr15_+_29025090 1.83 ENSDART00000131755
si:ch211-137a8.2
chr19_+_46113828 1.82 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr15_+_28175638 1.81 ENSDART00000037119
solute carrier family 46 (folate transporter), member 1
chr25_-_25575717 1.81 ENSDART00000067138
hypermethylated in cancer 1 like
chr21_+_6114709 1.80 ENSDART00000065858
folylpolyglutamate synthase
chr7_-_55633475 1.80 ENSDART00000149478
galactosamine (N-acetyl)-6-sulfatase
chr15_+_17406920 1.76 ENSDART00000081059
ribosomal protein S6 kinase b, polypeptide 1b
chr23_+_38159715 1.75 ENSDART00000137969
zgc:112994
chr2_-_2096055 1.74 ENSDART00000126566
solute carrier family 22, member 23
chr7_+_17907883 1.74 ENSDART00000147564
metastasis associated 1 family, member 2
chr19_+_42660158 1.74 ENSDART00000018328
F-box and leucine-rich repeat protein 2
chr8_-_5267442 1.72 ENSDART00000155816
protein phosphatase 2, regulatory subunit B, alpha a
chr10_+_29138021 1.72 ENSDART00000025227
ENSDART00000123033
ENSDART00000034242
phosphatidylinositol binding clathrin assembly protein a
chr22_-_20695237 1.71 ENSDART00000112722
oogenesis-related gene
chr23_+_35426404 1.71 ENSDART00000164658
si:ch211-225h24.2
chr6_+_38626926 1.71 ENSDART00000190339
ATPase phospholipid transporting 10A
chr14_+_31509922 1.70 ENSDART00000124499
hypoxanthine phosphoribosyltransferase 1
chr8_+_21280360 1.70 ENSDART00000144488
inositol 1,4,5-trisphosphate receptor, type 3
chr15_-_43978141 1.68 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr20_-_31743817 1.68 ENSDART00000137679
SAM and SH3 domain containing 1a
chr6_+_296130 1.68 ENSDART00000073985
RNA binding fox-1 homolog 2
chr12_-_25150239 1.68 ENSDART00000038415
ENSDART00000135368
ras homolog family member Q
chr6_+_33537267 1.67 ENSDART00000040334
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr25_-_36263115 1.66 ENSDART00000143046
ENSDART00000139002
dihydrouridine synthase 2
chr14_+_14806851 1.65 ENSDART00000169235
FH2 domain containing 2
chr17_+_6538733 1.65 ENSDART00000193712
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr17_+_46387086 1.65 ENSDART00000157079
si:dkey-206p8.1
chr8_-_22542467 1.65 ENSDART00000182588
ENSDART00000134542
cold shock domain containing E1, RNA-binding
chr17_+_15535501 1.64 ENSDART00000002932
myristoylated alanine-rich protein kinase C substrate b
chr24_-_38083378 1.64 ENSDART00000056381
C-reactive protein 2
chr23_+_36616717 1.63 ENSDART00000042701
ENSDART00000192980
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr13_+_40815012 1.63 ENSDART00000016960
protein kinase, cGMP-dependent, type Ia
chr4_+_25181572 1.62 ENSDART00000078529
ENSDART00000136643
Kin17 DNA and RNA binding protein
chr9_+_38588081 1.61 ENSDART00000031127
ENSDART00000131784
sorting nexin 4
chr3_+_34149337 1.61 ENSDART00000006091
coactivator-associated arginine methyltransferase 1
chr6_-_37744430 1.60 ENSDART00000150177
ENSDART00000149722
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr3_-_34136778 1.60 ENSDART00000131951
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr1_+_36772348 1.60 ENSDART00000109314
Rho GTPase activating protein 10
chr16_+_35535171 1.59 ENSDART00000167001
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr22_-_11054244 1.59 ENSDART00000105823
insulin receptor b
chr2_-_15040345 1.59 ENSDART00000109657
si:dkey-10f21.4
chr18_-_38271298 1.58 ENSDART00000143016
cell cycle associated protein 1b
chr1_+_38142354 1.58 ENSDART00000179352
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr14_-_31618243 1.58 ENSDART00000016592
membrane magnesium transporter 1
chr23_+_13533885 1.58 ENSDART00000144386
uridine-cytidine kinase 1-like 1b
chr11_+_19433936 1.58 ENSDART00000162081
prickle homolog 2b
chr10_-_3427589 1.57 ENSDART00000133452
ENSDART00000037183
transmembrane p24 trafficking protein 2
chr7_-_49800755 1.55 ENSDART00000180072
four jointed box 1
chr4_+_9011448 1.54 ENSDART00000192357
sorting and assembly machinery component 50 homolog, like
chr15_-_41689981 1.53 ENSDART00000059327
splA/ryanodine receptor domain and SOCS box containing 4b
chr6_+_40992409 1.52 ENSDART00000151419
transforming growth factor, alpha
chr14_+_989733 1.51 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr13_+_37653851 1.51 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
PHD finger protein 3
chr24_+_37800102 1.49 ENSDART00000187591
TEL2, telomere maintenance 2, homolog (S. cerevisiae)
chr22_+_30047245 1.47 ENSDART00000142857
ENSDART00000141247
ENSDART00000140015
ENSDART00000040538
adducin 3 (gamma) a
chr17_-_6955082 1.47 ENSDART00000109228
zinc finger and BTB domain containing 24
chr2_-_42492445 1.47 ENSDART00000139929
extended synaptotagmin-like protein 2a
chr23_-_16692312 1.47 ENSDART00000046784
FK506 binding protein 1Ab
chr5_+_1624359 1.47 ENSDART00000165431
protein phosphatase 1 catalytic subunit gamma
chr5_-_29531948 1.46 ENSDART00000098360
arrestin domain containing 1a
chr25_-_25575241 1.45 ENSDART00000150636
hypermethylated in cancer 1 like
chr8_+_18010978 1.45 ENSDART00000039887
ENSDART00000144532
single stranded DNA binding protein 3b
chr24_-_25144441 1.44 ENSDART00000152104
pleckstrin homology-like domain, family B, member 2b
chr14_+_3507326 1.44 ENSDART00000159326
glutathione S-transferase pi 1
chr16_+_35535375 1.44 ENSDART00000171675
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr14_-_24110251 1.44 ENSDART00000079226
cytoplasmic polyadenylation element binding protein 4a
chr17_+_23730089 1.43 ENSDART00000034913
zgc:91976
chr15_+_28410664 1.43 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr5_-_48680580 1.43 ENSDART00000031194
LysM, putative peptidoglycan-binding, domain containing 3
chr6_+_27991943 1.43 ENSDART00000143974
ENSDART00000141354
ENSDART00000088914
ENSDART00000139367
angiomotin like 2a
chr6_-_39006449 1.42 ENSDART00000150885
vitamin D receptor b
chr8_+_26868105 1.42 ENSDART00000005337
ribosomal modification protein rimK-like family member A
chr25_+_16194979 1.42 ENSDART00000185592
ENSDART00000158582
ENSDART00000161109
ENSDART00000139013
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr14_-_16754262 1.41 ENSDART00000001159
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr17_-_6954719 1.39 ENSDART00000188180
zinc finger and BTB domain containing 24
chr5_-_23118290 1.39 ENSDART00000132857
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr14_-_24110062 1.38 ENSDART00000177062
cytoplasmic polyadenylation element binding protein 4a
chr5_+_59030096 1.38 ENSDART00000179814
ENSDART00000110182
rabaptin, RAB GTPase binding effector protein 1
chr9_-_28255029 1.37 ENSDART00000160387
cyclin Y-like 1
chr12_+_36428052 1.35 ENSDART00000131300
unkempt family zinc finger
chr14_-_1200854 1.35 ENSDART00000106672
ADP-ribosylation factor-like 9
chr17_+_50261603 1.35 ENSDART00000154503
ENSDART00000154467
synaptotagmin binding, cytoplasmic RNA interacting protein, like
chr1_+_14454663 1.34 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr8_+_44623540 1.33 ENSDART00000141513
G protein-coupled receptor kinase 5 like
chr11_+_31324335 1.33 ENSDART00000088093
signal-induced proliferation-associated 1 like 2
chr16_+_19637384 1.33 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr16_+_33144306 1.32 ENSDART00000101953
rhomboid, veinlet-like 2 (Drosophila)
chr11_+_6902946 1.31 ENSDART00000144006
CREB regulated transcription coactivator 1b
chr1_+_6226135 1.30 ENSDART00000108816
FAST kinase domains 2
chr12_-_34852342 1.29 ENSDART00000152968
si:dkey-21c1.1
chr15_-_41689684 1.28 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr24_-_38138307 1.27 ENSDART00000189178
C-reactive protein 7
chr23_+_9230431 1.27 ENSDART00000187676
ENSDART00000125122
ENSDART00000190980
ENSDART00000141235
acyl-CoA synthetase short chain family member 2
chr22_+_737211 1.26 ENSDART00000017305
zinc finger protein 76
chr24_-_34335265 1.26 ENSDART00000128690
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr21_-_32036597 1.26 ENSDART00000114964
zgc:165573
chr18_-_39787040 1.25 ENSDART00000169916
Dmx-like 2
chr18_+_6857071 1.25 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr23_+_35847538 1.25 ENSDART00000143935
retinoic acid receptor gamma a
chr3_-_20118342 1.25 ENSDART00000139902
selenoprotein W, 2a
chr1_-_36772147 1.24 ENSDART00000053369
protein arginine methyltransferase 9
chr7_-_18877109 1.24 ENSDART00000113593
MLLT3, super elongation complex subunit
chr8_-_18010735 1.24 ENSDART00000125014
acyl-CoA thioesterase 11b
chr4_-_25181552 1.23 ENSDART00000066930
ATP synthase F1 subunit gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of arnt2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.3 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.9 2.6 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.7 5.0 GO:0002931 response to ischemia(GO:0002931)
0.7 2.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.7 2.6 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.6 8.2 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.6 5.6 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.6 1.8 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle cell differentiation(GO:2001014)
0.6 1.7 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099) hypoxanthine metabolic process(GO:0046100)
0.5 2.7 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.5 2.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.5 2.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.5 1.5 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.5 6.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.5 2.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.5 2.4 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.5 2.8 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.5 2.4 GO:0010586 miRNA metabolic process(GO:0010586)
0.4 3.5 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.4 5.4 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.4 1.3 GO:0097401 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.4 1.7 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.4 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4 2.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.4 2.8 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.4 1.9 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.4 2.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 2.5 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.4 2.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.3 4.1 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 1.3 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.3 1.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 2.0 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 1.0 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.3 0.9 GO:0046833 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.3 1.2 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.3 1.2 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.3 2.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.3 1.4 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.3 2.1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.3 4.4 GO:0090279 regulation of calcium ion import(GO:0090279)
0.3 0.5 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.2 2.2 GO:0045741 regulation of epidermal growth factor-activated receptor activity(GO:0007176) positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 1.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 1.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 0.9 GO:0021755 eurydendroid cell differentiation(GO:0021755)
0.2 1.6 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.2 0.7 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.2 0.7 GO:0036314 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 1.1 GO:0032196 transposition(GO:0032196)
0.2 0.9 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 2.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 1.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 0.6 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.2 1.3 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 1.1 GO:0021516 dorsal spinal cord development(GO:0021516) anterior lateral line nerve development(GO:0048909)
0.2 1.2 GO:0010269 response to selenium ion(GO:0010269)
0.2 2.5 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.2 1.6 GO:0044211 CTP salvage(GO:0044211)
0.2 3.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 0.9 GO:0006972 hyperosmotic response(GO:0006972)
0.2 0.7 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.2 1.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.2 0.7 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.2 1.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 2.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 5.4 GO:0045332 phospholipid translocation(GO:0045332)
0.2 2.4 GO:0045116 protein neddylation(GO:0045116)
0.2 0.6 GO:0042148 strand invasion(GO:0042148)
0.1 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.7 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 3.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 4.0 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.1 0.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 3.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.5 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 1.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.9 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 1.1 GO:0051597 response to methylmercury(GO:0051597)
0.1 0.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.5 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 1.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 3.6 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 1.7 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 2.6 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1 1.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 3.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.6 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.1 2.0 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 2.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.6 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.5 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.4 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 1.3 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.4 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.1 1.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.1 2.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 4.4 GO:0006400 tRNA modification(GO:0006400)
0.1 1.4 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 7.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 3.1 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 2.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:0019860 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.1 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.1 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.1 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.5 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.4 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 0.7 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 1.4 GO:0015914 phospholipid transport(GO:0015914)
0.1 4.5 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.1 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 2.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 2.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 3.1 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 2.1 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.0 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.1 GO:2000257 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.9 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0015874 norepinephrine transport(GO:0015874)
0.0 1.7 GO:0051298 centrosome duplication(GO:0051298)
0.0 1.6 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 1.6 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.0 2.1 GO:0008033 tRNA processing(GO:0008033)
0.0 1.0 GO:0051784 negative regulation of nuclear division(GO:0051784)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 2.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0080111 DNA demethylation(GO:0080111)
0.0 3.1 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.2 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 1.4 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.9 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.9 GO:0060037 pharyngeal system development(GO:0060037)
0.0 2.6 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 1.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 2.6 GO:0016573 histone acetylation(GO:0016573)
0.0 1.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 5.2 GO:0006869 lipid transport(GO:0006869)
0.0 1.9 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.9 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0039023 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.0 1.6 GO:0031929 TOR signaling(GO:0031929)
0.0 0.1 GO:0021767 mammillary body development(GO:0021767)
0.0 0.1 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.4 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 1.0 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.0 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 1.3 GO:0090630 activation of GTPase activity(GO:0090630)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0070209 ASTRA complex(GO:0070209)
0.5 2.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.4 1.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.4 1.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.4 7.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 5.5 GO:0000792 heterochromatin(GO:0000792)
0.3 5.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 4.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 1.6 GO:0005899 insulin receptor complex(GO:0005899)
0.3 0.9 GO:0042382 paraspeckles(GO:0042382)
0.3 1.3 GO:0043291 RAVE complex(GO:0043291)
0.3 1.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 1.0 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.2 1.5 GO:0016589 NURF complex(GO:0016589)
0.2 2.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 1.4 GO:0005784 Sec61 translocon complex(GO:0005784)
0.2 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 2.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.2 GO:1902636 kinociliary basal body(GO:1902636)
0.2 2.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 1.5 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.2 1.2 GO:0001650 fibrillar center(GO:0001650)
0.2 1.1 GO:0070847 core mediator complex(GO:0070847)
0.2 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.2 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 2.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.4 GO:0097361 CIA complex(GO:0097361)
0.1 0.4 GO:0010369 chromocenter(GO:0010369)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.3 GO:0035101 FACT complex(GO:0035101)
0.1 2.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 2.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.6 GO:0030914 STAGA complex(GO:0030914)
0.1 5.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.7 GO:0030667 secretory granule membrane(GO:0030667)
0.1 3.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.1 1.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 4.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.4 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 0.6 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.9 GO:0005903 brush border(GO:0005903)
0.1 1.2 GO:0030686 90S preribosome(GO:0030686)
0.1 2.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 6.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 1.5 GO:0043186 P granule(GO:0043186)
0.0 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 2.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.6 GO:0044545 NSL complex(GO:0044545)
0.0 0.8 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.9 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 1.8 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 6.6 GO:0005764 lysosome(GO:0005764)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 22.1 GO:0005654 nucleoplasm(GO:0005654)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0044224 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 2.6 GO:0010008 endosome membrane(GO:0010008)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.4 GO:0019867 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 1.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0031941 filamentous actin(GO:0031941)
0.0 2.6 GO:0005938 cell cortex(GO:0005938)
0.0 1.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.3 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:1990715 mRNA CDS binding(GO:1990715)
1.0 3.9 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.9 2.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.6 1.7 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.5 2.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 1.4 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.5 1.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 1.7 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.4 1.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.4 0.8 GO:0003994 aconitate hydratase activity(GO:0003994)
0.4 3.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.4 1.8 GO:0005542 folic acid binding(GO:0005542)
0.4 7.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4 2.5 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.3 1.9 GO:0008142 oxysterol binding(GO:0008142)
0.3 1.6 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.3 1.6 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3 1.6 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.3 3.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 5.8 GO:0008301 DNA binding, bending(GO:0008301)
0.3 7.3 GO:0030371 translation repressor activity(GO:0030371)
0.3 2.7 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.3 6.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.5 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3 1.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 0.9 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3 2.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 1.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 1.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.3 1.3 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 1.0 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.2 8.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.2 1.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 1.4 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 4.0 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 3.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 1.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.6 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 1.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 1.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.2 2.0 GO:0005487 nuclear export signal receptor activity(GO:0005049) nucleocytoplasmic transporter activity(GO:0005487)
0.2 1.3 GO:0030274 LIM domain binding(GO:0030274)
0.2 5.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 1.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 2.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.8 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 2.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.2 5.9 GO:0035064 methylated histone binding(GO:0035064)
0.2 4.1 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2 0.9 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.0 GO:0070888 E-box binding(GO:0070888)
0.1 3.6 GO:0005112 Notch binding(GO:0005112)
0.1 1.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 1.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 3.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.6 GO:0008143 poly(A) binding(GO:0008143)
0.1 9.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 2.7 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 2.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.2 GO:0002020 protease binding(GO:0002020)
0.1 0.7 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 1.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 3.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 4.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 2.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.5 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 2.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 3.1 GO:0000049 tRNA binding(GO:0000049)
0.1 4.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.3 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:0001032 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.2 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 1.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 6.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 3.7 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0005334 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330) norepinephrine transmembrane transporter activity(GO:0005333) norepinephrine:sodium symporter activity(GO:0005334)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 4.4 GO:0005319 lipid transporter activity(GO:0005319)
0.0 2.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 3.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 5.6 GO:0016874 ligase activity(GO:0016874)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 4.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.2 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.5 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 2.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 9.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 2.1 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.9 GO:0000146 microfilament motor activity(GO:0000146) actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.9 GO:0042802 identical protein binding(GO:0042802)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.7 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 2.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 6.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 2.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 3.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 9.3 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 2.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 1.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 1.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 2.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 1.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 1.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 2.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 2.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 5.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 3.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.7 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 3.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 6.2 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 2.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production