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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for arnt

Z-value: 0.71

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Transcription factors associated with arnt

Gene Symbol Gene ID Gene Info
ENSDARG00000021855 aryl hydrocarbon receptor nuclear translocator
ENSDARG00000115999 aryl hydrocarbon receptor nuclear translocator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arntdr11_v1_chr16_-_4610255_4610278-0.961.7e-10Click!

Activity profile of arnt motif

Sorted Z-values of arnt motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_3864040 1.61 ENSDART00000013743
golgi reassembly stacking protein 2
chr25_-_1124851 1.60 ENSDART00000067558
spastic paraplegia 11
chr17_+_24613255 1.55 ENSDART00000064738
ATP synthase inhibitory factor subunit 1b
chr16_-_28727763 1.47 ENSDART00000149575
DC-STAMP domain containing 1
chr3_+_52899801 1.34 ENSDART00000058958
ATPase 13A1
chr20_-_39596338 1.24 ENSDART00000023531
hes-related family bHLH transcription factor with YRPW motif 2
chr21_-_5066462 1.22 ENSDART00000067733
zgc:77838
chr3_+_34180835 1.17 ENSDART00000055252
translocase of inner mitochondrial membrane 29
chr12_+_19384615 1.11 ENSDART00000078266
ribosomal L1 domain containing 1
chr18_+_26422124 0.98 ENSDART00000060245
cathepsin H
chr12_-_990149 0.95 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr9_+_907459 0.94 ENSDART00000034850
ENSDART00000144114
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr8_+_40081403 0.94 ENSDART00000138036
leucine rich repeat containing 75Ba
chr13_-_3516473 0.93 ENSDART00000146240
parkin RBR E3 ubiquitin protein ligase
chr19_+_48102560 0.93 ENSDART00000164464
UTP18 small subunit (SSU) processome component
chr19_+_627899 0.92 ENSDART00000148508
telomerase reverse transcriptase
chr18_-_14691727 0.90 ENSDART00000010129
peptide deformylase, mitochondrial
chr13_+_31402067 0.90 ENSDART00000019202
tudor domain containing 9
chr19_-_27966526 0.90 ENSDART00000141896
ubiquitin-conjugating enzyme E2Q family-like 1
chr3_-_3496738 0.86 ENSDART00000186849

chr8_-_52859301 0.85 ENSDART00000162004
nuclear receptor subfamily 5, group A, member 1a
chr3_+_36313532 0.85 ENSDART00000151305
solute carrier family 16, member 6b
chr23_-_35649000 0.85 ENSDART00000053310
transmembrane protein 18
chr21_-_20765338 0.84 ENSDART00000135940
growth hormone receptor b
chr5_+_57210237 0.84 ENSDART00000167660
praja ring finger ubiquitin ligase 2
chr16_+_28728347 0.84 ENSDART00000149240
si:dkey-24i24.3
chr25_-_6011034 0.82 ENSDART00000075197
ENSDART00000136054
sorting nexin 22
chr2_+_16160906 0.82 ENSDART00000135783
selenoprotein J
chr24_-_24959607 0.80 ENSDART00000146930
ENSDART00000184482
pyruvate dehydrogenase kinase, isozyme 3a
chr7_-_38340674 0.80 ENSDART00000075782
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr15_+_6652396 0.79 ENSDART00000192813
ENSDART00000157678
NOP53 ribosome biogenesis factor
chr15_-_4580763 0.78 ENSDART00000008170
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr25_+_30298377 0.75 ENSDART00000153622
chromosome 11 open reading frame 96
chr20_-_22798794 0.74 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr3_+_13929860 0.72 ENSDART00000164179
synaptonemal complex central element protein 2
chr15_-_36533322 0.72 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
chr16_-_54800202 0.72 ENSDART00000059560
ENSDART00000161833
KH domain containing 4, pre-mRNA splicing factor
chr6_+_12968101 0.71 ENSDART00000013781
minichromosome maintenance complex component 6
chr9_+_3282369 0.71 ENSDART00000044128
histone acetyltransferase 1
chr19_-_24555935 0.68 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr7_-_55539738 0.67 ENSDART00000168721
ENSDART00000013796
ENSDART00000148514
adenine phosphoribosyltransferase
chr10_+_15408501 0.67 ENSDART00000123818
ENSDART00000192395
ENSDART00000003839
neurolysin (metallopeptidase M3 family)
chr23_+_2421689 0.66 ENSDART00000180200
t-complex 1
chr17_-_53329704 0.66 ENSDART00000193895
exonuclease 3'-5' domain containing 1
chr20_-_16171297 0.66 ENSDART00000012476
cytochrome c oxidase assembly factor 7
chr22_+_17261801 0.66 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr23_+_22656477 0.66 ENSDART00000009337
ENSDART00000133322
enolase 1a, (alpha)
chr1_+_52560549 0.65 ENSDART00000167514
ATP-binding cassette, sub-family A (ABC1), member 1A
chr7_+_20031202 0.65 ENSDART00000052904
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr7_-_74090168 0.64 ENSDART00000050528
tyrosinase-related protein 1a
chr20_+_39457598 0.63 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr3_-_34180364 0.62 ENSDART00000151819
ENSDART00000003133
Yip1 domain family, member 2
chr21_+_15704556 0.62 ENSDART00000024858
ENSDART00000146909
coiled-coil-helix-coiled-coil-helix domain containing 10
chr8_+_17184602 0.62 ENSDART00000050228
ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr12_-_20350629 0.62 ENSDART00000066384
hemoglobin beta embryonic-2
chr22_+_38914983 0.60 ENSDART00000085701
SUMO1/sentrin specific peptidase 5
chr11_-_3959889 0.60 ENSDART00000159683
polybromo 1
chr21_-_25618175 0.59 ENSDART00000133512
FOS-like antigen 1b
chr23_-_38160024 0.59 ENSDART00000087112
prefoldin subunit 4
chr1_-_39943596 0.58 ENSDART00000149730
storkhead box 2a
chr5_+_68807170 0.58 ENSDART00000017849
hairy and enhancer of split related-7
chr25_+_21833287 0.58 ENSDART00000187606
creatine kinase, mitochondrial 1
chr19_-_24555623 0.57 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr11_+_24900123 0.56 ENSDART00000044987
ENSDART00000148023
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr20_+_7209972 0.56 ENSDART00000189169
ENSDART00000136974
si:dkeyp-51f12.3
chr5_+_62723233 0.55 ENSDART00000183718
nanos homolog 2
chr11_+_41540862 0.55 ENSDART00000173210
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr3_+_55122662 0.55 ENSDART00000128380
hemoglobin beta embryonic-1.2
chr23_+_2421313 0.55 ENSDART00000126038
t-complex 1
chr10_+_11398111 0.54 ENSDART00000064210
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr23_+_36653376 0.53 ENSDART00000053189
G protein-coupled receptor 182
chr14_+_14836468 0.53 ENSDART00000166728
si:dkey-102m7.3
chr7_-_24364536 0.52 ENSDART00000064789
thioredoxin
chr2_-_40191603 0.51 ENSDART00000180691
si:ch211-122l24.6
chr13_-_280652 0.51 ENSDART00000193627
solute carrier family 30 (zinc transporter), member 6
chr25_+_35774544 0.51 ENSDART00000034737
ENSDART00000188162
copine VIII
chr18_-_17020231 0.50 ENSDART00000129146
TBC1 domain family, member 15
chr2_+_44426609 0.50 ENSDART00000112711
ENSDART00000154188
potassium voltage-gated channel, shaker-related subfamily, beta member 1 b
chr18_+_184746 0.49 ENSDART00000140897
La ribonucleoprotein domain family, member 6a
chr24_+_3963684 0.49 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
phosphofructokinase, platelet a
chr17_+_19499157 0.49 ENSDART00000077804
solute carrier family 22, member 15
chr6_-_18366287 0.49 ENSDART00000171198
ENSDART00000160679
si:dkey-31g6.6
chr7_+_22823889 0.48 ENSDART00000127467
ENSDART00000148576
ENSDART00000149993
phosphorylase, glycogen, muscle b
chr15_-_25584888 0.48 ENSDART00000127571
si:dkey-54n8.2
chr13_-_280827 0.47 ENSDART00000144819
solute carrier family 30 (zinc transporter), member 6
chr7_+_29053217 0.47 ENSDART00000134332
ENSDART00000137241
SIN3-HDAC complex associated factor, like
chr5_-_34997630 0.47 ENSDART00000170684
basic transcription factor 3
chr21_-_275377 0.47 ENSDART00000157509
relaxin 1
chr25_-_37501371 0.46 ENSDART00000160498

chr19_+_18903533 0.46 ENSDART00000157523
ENSDART00000166562
solute carrier family 39 (zinc transporter), member 7
chr3_-_60602432 0.46 ENSDART00000163235
serine/arginine-rich splicing factor 2b
chr18_+_14693682 0.46 ENSDART00000132249
URI1, prefoldin-like chaperone
chr12_+_28799988 0.46 ENSDART00000022724
pyridoxamine 5'-phosphate oxidase
chr7_+_44715224 0.45 ENSDART00000184630
si:dkey-56m19.5
chr3_+_60277300 0.45 ENSDART00000170977
SEC14-like lipid binding 1
chr14_+_23518110 0.45 ENSDART00000112930
si:ch211-221f10.2
chr12_+_16284086 0.45 ENSDART00000013360
ENSDART00000141169
protein phosphatase 1, regulatory subunit 3Cb
chr13_+_22480496 0.45 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
LIM domain binding 3a
chr3_+_1150348 0.45 ENSDART00000148524
nucleolar protein 12
chr2_-_21621878 0.45 ENSDART00000189540
zgc:55781
chr18_+_34861568 0.45 ENSDART00000192825

chr7_-_73815262 0.44 ENSDART00000185351
zgc:165555
chr20_-_54259780 0.44 ENSDART00000172631
FK506 binding protein 3
chr20_-_29683754 0.44 ENSDART00000130599
ENSDART00000015928
ENSDART00000131219
si:ch211-195d17.2
chr16_+_49601838 0.44 ENSDART00000168570
ENSDART00000159236
si:dkey-82o10.4
chr4_+_7876197 0.42 ENSDART00000111986
ENSDART00000189601
cell division cycle 123 homolog (S. cerevisiae)
chr9_+_8898835 0.42 ENSDART00000147820
NAD(P)HX dehydratase
chr12_+_2677303 0.41 ENSDART00000093113
anthrax toxin receptor 1c
chr7_+_20030888 0.41 ENSDART00000192808
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr9_-_2573121 0.41 ENSDART00000181340
secernin 3
chr10_-_34089779 0.40 ENSDART00000140070
Pim proto-oncogene, serine/threonine kinase, related 144
chr19_+_18812805 0.39 ENSDART00000187164
ENSDART00000172412
carnitine O-acetyltransferase b
chr14_+_35748206 0.39 ENSDART00000177391
glutamate receptor, ionotropic, AMPA 2b
chr3_-_16010968 0.39 ENSDART00000080672
mitochondrial ribosomal protein S34
chr11_-_25384213 0.38 ENSDART00000103650
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb
chr25_+_3328487 0.38 ENSDART00000181143
lactate dehydrogenase Bb
chr20_+_16170848 0.38 ENSDART00000182115
zyg-11 homolog (C. elegans)
chr14_+_35748385 0.37 ENSDART00000064617
ENSDART00000074671
ENSDART00000172803
glutamate receptor, ionotropic, AMPA 2b
chr20_+_19423823 0.37 ENSDART00000152216
zinc finger protein 513a
chr4_-_14192254 0.37 ENSDART00000143804
pseudouridylate synthase 7-like
chr22_-_607812 0.37 ENSDART00000145983
cyclin-dependent kinase inhibitor 1A
chr23_-_38054 0.36 ENSDART00000170393

chr19_-_13933204 0.35 ENSDART00000158059
tRNA selenocysteine 1 associated protein 1a
chr20_+_1196386 0.34 ENSDART00000041192
LYR motif containing 2
chr23_+_35714574 0.34 ENSDART00000164616
tubulin, alpha 1c
chr21_-_28920245 0.34 ENSDART00000132884
CXXC finger protein 5a
chr9_-_2572790 0.34 ENSDART00000135076
ENSDART00000016710
secernin 3
chr21_+_30470809 0.34 ENSDART00000171648
ENSDART00000126678
ENSDART00000003335
ENSDART00000133478
ENSDART00000140811
ENSDART00000147375
sorting nexin 12
chr2_+_9970942 0.32 ENSDART00000153063
SEC22 homolog B, vesicle trafficking protein a
chr21_-_36948 0.32 ENSDART00000181230
junction mediating and regulatory protein, p53 cofactor
chr3_+_23488652 0.32 ENSDART00000126282
nuclear receptor subfamily 1, group d, member 1
chr12_-_9700605 0.32 ENSDART00000161063
HEAT repeat containing 1
chr18_-_21218851 0.32 ENSDART00000060160
calbindin 2a
chr13_-_4223955 0.31 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr6_-_54078623 0.31 ENSDART00000154076
hyaluronoglucosaminidase 1
chr4_+_25558849 0.31 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
chr16_+_9713850 0.31 ENSDART00000164103
extracellular matrix protein 1b
chr23_+_37086159 0.31 ENSDART00000074407
ceramide-1-phosphate transfer protein
chr1_-_38415158 0.31 ENSDART00000018533
15-hydroxyprostaglandin dehydrogenase
chr5_-_31716713 0.31 ENSDART00000131443
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr17_-_31164219 0.31 ENSDART00000055754
protein kinase domain containing, cytoplasmic b
chr23_-_16682186 0.31 ENSDART00000020810
syndecan binding protein (syntenin) 2
chr6_+_12006557 0.31 ENSDART00000128024
WD repeat, sterile alpha motif and U-box domain containing 1
chr14_+_24215046 0.30 ENSDART00000079215
stanniocalcin 2a
chr18_-_44908479 0.29 ENSDART00000169636
si:ch211-71n6.4
chr9_-_24120855 0.29 ENSDART00000101571
tRNA-yW synthesizing protein 5
chr7_+_66048102 0.28 ENSDART00000104523
aryl hydrocarbon receptor nuclear translocator-like 1b
chr17_+_43468732 0.27 ENSDART00000055487
charged multivesicular body protein 3
chr24_+_32668675 0.27 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
chr6_-_23931442 0.27 ENSDART00000160547
SEC16 homolog B, endoplasmic reticulum export factor
chr11_-_8269227 0.26 ENSDART00000127202
ENSDART00000158079
ENSDART00000158748
si:cabz01021067.1
Pim proto-oncogene, serine/threonine kinase, related 202
chr7_-_35036770 0.26 ENSDART00000123174
galanin receptor 1b
chr20_-_26531850 0.26 ENSDART00000183317
ENSDART00000131994
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr16_-_30927764 0.25 ENSDART00000156804
solute carrier family 45, member 4
chr17_-_31212420 0.25 ENSDART00000086511
RNA pseudouridylate synthase domain containing 2
chr20_+_8028613 0.25 ENSDART00000085668
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr13_+_36146415 0.24 ENSDART00000140301
si:ch211-259k16.3
chr13_+_22480857 0.24 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
LIM domain binding 3a
chr14_-_1454045 0.24 ENSDART00000161460
phosphoethanolamine methyltransferase
chr9_-_18424844 0.24 ENSDART00000154351
ecto-NOX disulfide-thiol exchanger 1
chr4_-_2727491 0.24 ENSDART00000141760
ENSDART00000039083
ENSDART00000134442
solute carrier organic anion transporter family, member 1C1
chr13_+_41917606 0.23 ENSDART00000114741
polymerase (RNA) I polypeptide B
chr5_-_26950374 0.23 ENSDART00000050542
HtrA serine peptidase 4
chr17_-_45733401 0.23 ENSDART00000185727
ADP-ribosylation factor 6b
chr1_-_59422880 0.23 ENSDART00000167244
si:ch211-188p14.2
chr19_+_34311374 0.22 ENSDART00000086617
gamma-aminobutyric acid (GABA) B receptor, 2
chr24_-_38644937 0.22 ENSDART00000170194
solute carrier family 6, member 16b
chr6_+_22326624 0.22 ENSDART00000020333
ribonucleic acid export 1
chr16_-_28836523 0.22 ENSDART00000108596
ENSDART00000142920
perilipin 6
chr20_-_49117438 0.21 ENSDART00000057700
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr18_-_40684756 0.21 ENSDART00000113799
ENSDART00000139042
si:ch211-132b12.7
chr2_+_49860722 0.21 ENSDART00000144060
ribosomal protein L37
chr9_+_51147764 0.21 ENSDART00000188480
interferon induced with helicase C domain 1
chr1_+_12195700 0.20 ENSDART00000040307
tudor domain containing 7 a
chr23_+_21459263 0.20 ENSDART00000104209
hairy-related 4, tandem duplicate 3
chr17_-_19534474 0.20 ENSDART00000192469
cytochrome P450, family 26, subfamily C, polypeptide 1
chr13_-_30645965 0.20 ENSDART00000109307
zinc finger, CCHC domain containing 24
chr8_+_26059677 0.20 ENSDART00000009178
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr22_-_12160283 0.20 ENSDART00000146785
ENSDART00000128176
transmembrane protein 163b
chr14_-_17599452 0.19 ENSDART00000080042
RAB33A, member RAS oncogene family
chr5_-_16475374 0.19 ENSDART00000134274
ENSDART00000136004
piwi-like RNA-mediated gene silencing 2
chr21_+_25068215 0.19 ENSDART00000167523
ENSDART00000189259
DIX domain containing 1b
chr23_+_36101185 0.19 ENSDART00000103139
homeobox C8a
chr23_-_14769523 0.18 ENSDART00000054909
glutathione synthetase
chr13_+_41022502 0.18 ENSDART00000026808
dickkopf WNT signaling pathway inhibitor 1a
chr19_+_22850657 0.18 ENSDART00000130472
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr14_-_15739969 0.18 ENSDART00000164841
ENSDART00000192635
neuralized E3 ubiquitin protein ligase 1B
chr10_+_38526496 0.18 ENSDART00000144329
alkaline ceramidase 3
chr4_+_41789497 0.18 ENSDART00000126634
si:dkey-237m9.2
chr3_-_24093144 0.18 ENSDART00000103982
nuclear factor, erythroid 2-like 1a
chr19_-_29832876 0.18 ENSDART00000005119
eukaryotic translation initiation factor 3, subunit I
chr15_+_7054754 0.17 ENSDART00000149800
forkhead box L2a
chr3_+_54887782 0.17 ENSDART00000018205
arylalkylamine N-acetyltransferase 2
chr22_+_3238474 0.17 ENSDART00000157954
si:ch1073-178p5.3
chr6_-_10988741 0.17 ENSDART00000090709
coenzyme Q7 homolog, ubiquinone (yeast)
chr11_-_27739049 0.17 ENSDART00000021949
family with sequence similarity 120A
chr24_+_41690545 0.17 ENSDART00000160069
laminin, alpha 1
chr16_+_32136550 0.17 ENSDART00000147526
sphingosine kinase 2
chr11_+_36379293 0.17 ENSDART00000135360
ataxin 7-like 2a
chr11_-_21304452 0.17 ENSDART00000163008
si:dkey-85p17.3

Network of associatons between targets according to the STRING database.

First level regulatory network of arnt

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.4 1.2 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.3 0.9 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.3 0.8 GO:0042940 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.2 1.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 1.7 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 0.7 GO:0006168 adenine salvage(GO:0006168)
0.2 0.7 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 0.5 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.2 0.5 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 1.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.5 GO:1903817 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.8 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.3 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.9 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 0.4 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.7 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.3 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 0.6 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.8 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.6 GO:0001966 thigmotaxis(GO:0001966)
0.1 0.7 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.5 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.9 GO:0030325 adrenal gland development(GO:0030325)
0.1 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.2 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.1 0.6 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.2 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.5 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:0035627 ceramide transport(GO:0035627)
0.0 0.6 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.2 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.2 GO:0043476 pigment accumulation(GO:0043476)
0.0 0.2 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 1.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.7 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.1 GO:0033212 iron assimilation(GO:0033212)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0030719 P granule organization(GO:0030719)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0003151 outflow tract morphogenesis(GO:0003151) atrial cardiac muscle cell development(GO:0055014)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.8 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.2 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 1.3 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.8 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.7 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 2.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.4 GO:0010165 response to X-ray(GO:0010165)
0.0 0.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.5 GO:0001757 somite specification(GO:0001757)
0.0 0.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 1.6 GO:0007030 Golgi organization(GO:0007030)
0.0 0.6 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 1.5 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.3 GO:0006457 protein folding(GO:0006457)
0.0 0.3 GO:0009648 photoperiodism(GO:0009648)
0.0 0.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.6 GO:0071277 cellular response to calcium ion(GO:0071277)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.3 0.9 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 0.7 GO:0033391 chromatoid body(GO:0033391)
0.2 0.8 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 0.8 GO:1990923 PET complex(GO:1990923)
0.1 0.7 GO:0000801 central element(GO:0000801)
0.1 1.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.6 GO:0016586 RSC complex(GO:0016586)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.9 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 1.4 GO:0030686 90S preribosome(GO:0030686)
0.1 0.5 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.6 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.8 GO:0043186 P granule(GO:0043186)
0.0 0.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.8 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 1.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 0.9 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.2 0.7 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.2 0.8 GO:0004903 growth hormone receptor activity(GO:0004903)
0.2 0.8 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.7 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.7 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.4 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.1 0.7 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0045545 syndecan binding(GO:0045545)
0.1 0.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 0.5 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.3 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.2 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.6 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 1.0 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.6 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.5 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 1.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.9 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.5 GO:0019843 rRNA binding(GO:0019843)
0.0 0.9 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination