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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for TCF4_id4_mespaa+mespab+mespba+mespbb

Z-value: 0.71

Motif logo

Transcription factors associated with TCF4_id4_mespaa+mespab+mespba+mespbb

Gene Symbol Gene ID Gene Info
ENSDARG00000107408 transcription factor 4
ENSDARG00000045131 inhibitor of DNA binding 4
ENSDARG00000017078 mesoderm posterior aa
ENSDARG00000030347 mesoderm posterior ba
ENSDARG00000068761 mesoderm posterior ab
ENSDARG00000097947 mesoderm posterior bb
ENSDARG00000110553 mesoderm posterior ba
ENSDARG00000114890 mesoderm posterior aa

Activity-expression correlation:

Activity profile of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Sorted Z-values of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_58751504 4.59 ENSDART00000024185
zgc:56231
chr13_-_21672131 4.48 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr2_-_47620806 3.61 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr10_-_25217347 2.80 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr10_+_1052591 2.51 ENSDART00000123405
unc-5 netrin receptor C
chr2_-_50225411 2.49 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr21_-_43666420 2.41 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
chr22_+_17828267 2.38 ENSDART00000136016
hyaluronan and proteoglycan link protein 4
chr22_-_25612680 2.37 ENSDART00000114167
si:ch211-12h2.8
chr15_+_38299385 2.23 ENSDART00000142403
si:dkey-24p1.6
chr21_-_21178410 2.14 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
FtsJ RNA methyltransferase homolog 1
chr2_+_27855102 2.14 ENSDART00000150330
bucky ball
chr15_+_38299563 2.12 ENSDART00000099375
si:dkey-24p1.6
chr6_+_153146 2.09 ENSDART00000097468
zinc finger, GATA-like protein 1
chr17_-_25331439 2.08 ENSDART00000155422
ENSDART00000082324
zona pellucida protein C
chr5_+_28271412 2.06 ENSDART00000031727
vesicle-associated membrane protein 8 (endobrevin)
chr2_+_27855346 2.02 ENSDART00000175159
ENSDART00000192645
bucky ball
chr3_+_42923275 2.01 ENSDART00000168228
transmembrane protein 184a
chr12_+_13091842 1.99 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr12_-_10512911 1.92 ENSDART00000124562
ENSDART00000106163
zgc:152977
chr17_+_1360192 1.90 ENSDART00000184561
SIVA1, apoptosis-inducing factor
chr18_-_25771553 1.89 ENSDART00000103046
zgc:162879
chr21_-_30293224 1.82 ENSDART00000101051
stem-loop binding protein 2
chr8_+_45334255 1.80 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr22_-_10541372 1.79 ENSDART00000179708
si:dkey-42i9.4
chr1_-_34450622 1.76 ENSDART00000083736
LIM domain 7b
chr6_+_10333920 1.72 ENSDART00000151667
ENSDART00000151477
cordon-bleu WH2 repeat protein-like 1a
chr6_+_40523370 1.71 ENSDART00000033819
protein kinase C, delta a
chr5_-_22052852 1.67 ENSDART00000002938
myotubularin related protein 8
chr19_+_14454306 1.67 ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr1_+_24387659 1.67 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr7_+_57089354 1.62 ENSDART00000140702
secretory carrier membrane protein 2, like
chr1_-_18811517 1.60 ENSDART00000142026
si:dkey-167i21.2
chr5_-_23696926 1.59 ENSDART00000021462
ring finger protein 128a
chr7_-_48251234 1.57 ENSDART00000024062
ENSDART00000098904
cytoplasmic polyadenylation element binding protein 1b
chr22_-_17677947 1.54 ENSDART00000139911
tight junction protein 3
chr14_-_33278084 1.54 ENSDART00000132850
START domain containing 14
chr14_+_15155684 1.52 ENSDART00000167966
zgc:158852
chr14_-_33277743 1.50 ENSDART00000048130
START domain containing 14
chr13_-_9442942 1.44 ENSDART00000138833
glutaredoxin, cysteine rich 1
chr23_+_553396 1.43 ENSDART00000034707
LSM family member 14B
chr2_-_21819421 1.43 ENSDART00000121586
chromodomain helicase DNA binding protein 7
chr12_-_47601845 1.42 ENSDART00000169548
ENSDART00000182889
regulator of G protein signaling 7b
chr1_-_31105376 1.41 ENSDART00000132466
protein phosphatase 1 regulatory subunit 9A-like B
chr14_-_46198373 1.41 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr5_+_44846280 1.40 ENSDART00000084370
KN motif and ankyrin repeat domains 1a
chr5_-_15494164 1.39 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
TAO kinase 3a
chr20_-_13625588 1.38 ENSDART00000078893
synaptotagmin-like 3
chr15_+_784149 1.38 ENSDART00000155114
zinc finger protein 970
chr5_+_44846434 1.38 ENSDART00000145299
ENSDART00000136521
KN motif and ankyrin repeat domains 1a
chr10_+_29771256 1.38 ENSDART00000193195
hypoxia up-regulated 1
chr16_-_42066523 1.38 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr3_+_19665319 1.37 ENSDART00000007857
ENSDART00000193509
methyltransferase like 2A
chr10_-_31805923 1.37 ENSDART00000077785
vacuolar protein sorting 26 homolog B, like
chr12_-_23365737 1.36 ENSDART00000170376
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr9_-_34269066 1.35 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr8_+_16758304 1.34 ENSDART00000133514
ELOVL fatty acid elongase 7a
chr15_+_29025090 1.34 ENSDART00000131755
si:ch211-137a8.2
chr22_-_5171829 1.33 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr14_-_35672890 1.33 ENSDART00000074710
platelet derived growth factor c
chr14_+_591216 1.32 ENSDART00000169624
zgc:158257
chr24_-_31904924 1.31 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr5_-_37047147 1.31 ENSDART00000097712
ENSDART00000158974
finTRIM family, member 99
chr2_-_2096055 1.31 ENSDART00000126566
solute carrier family 22, member 23
chr7_-_18881358 1.30 ENSDART00000021502
MLLT3, super elongation complex subunit
chr21_-_34261677 1.29 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr3_-_34586403 1.28 ENSDART00000151515
septin 9a
chr9_-_28990649 1.26 ENSDART00000078823
protein tyrosine phosphatase, non-receptor type 4a
chr15_+_29024895 1.25 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
chr14_-_25930182 1.25 ENSDART00000018651
ENSDART00000147991
GTPase activating protein (SH3 domain) binding protein 1
chr7_+_67699009 1.23 ENSDART00000192810
zgc:162592
chr6_+_10338554 1.22 ENSDART00000186936
cordon-bleu WH2 repeat protein-like 1a
chr10_-_2942900 1.21 ENSDART00000002622
occludin a
chr17_-_2596125 1.21 ENSDART00000175740
zona pellucida glycoprotein 3, tandem duplicate 2
chr2_+_6253246 1.21 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr5_-_65662996 1.20 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr16_-_47381519 1.19 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
chr18_+_22220656 1.18 ENSDART00000191862
RHO family interacting cell polarization regulator 1
chr4_-_20177868 1.18 ENSDART00000003621
siaz-interacting nuclear protein
chr23_+_6586467 1.16 ENSDART00000081763
ENSDART00000121480
RNA binding motif protein 38
chr1_+_19764995 1.16 ENSDART00000138276
si:ch211-42i9.8
chr2_+_25658112 1.14 ENSDART00000051234
TRAF2 and NCK interacting kinase a
chr7_+_57088920 1.13 ENSDART00000024076
secretory carrier membrane protein 2, like
chr13_-_39254 1.13 ENSDART00000093222
general transcription factor IIA, 1-like
chr22_+_11756040 1.13 ENSDART00000105808
keratin 97
chr2_-_58075414 1.11 ENSDART00000161920
nectin cell adhesion molecule 4
chr6_+_60112200 1.10 ENSDART00000008243
PRELI domain containing 3
chr15_+_20239141 1.10 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr12_-_35393211 1.10 ENSDART00000137139
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr22_-_22164338 1.10 ENSDART00000183840
cell division cycle 34 homolog (S. cerevisiae) a
chr15_+_43906043 1.10 ENSDART00000010881
N-acetylated alpha-linked acidic dipeptidase 2
chr1_-_50247 1.10 ENSDART00000168428
immunoglobulin-like domain containing receptor 1a
chr5_+_26212621 1.09 ENSDART00000134432
occludin b
chr23_+_2728095 1.09 ENSDART00000066086
zgc:114123
chr14_-_21618005 1.08 ENSDART00000043162
receptor accessory protein 2
chr20_-_164300 1.07 ENSDART00000183354
si:ch211-241j12.3
chr18_+_45666489 1.07 ENSDART00000180147
ENSDART00000151351
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr14_-_45551572 1.07 ENSDART00000111410
glucosidase, alpha; neutral AB
chr5_-_23715861 1.06 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr17_-_30652738 1.05 ENSDART00000154960
SH3 and SYLF domain containing 1
chr16_+_46725087 1.03 ENSDART00000008920
RAB11a, member RAS oncogene family, like
chr10_-_1961930 1.02 ENSDART00000122446
teratocarcinoma-derived growth factor 1
chr19_-_18127808 1.01 ENSDART00000108627
sorting nexin 10a
chr17_-_2595736 1.01 ENSDART00000128797
zona pellucida glycoprotein 3, tandem duplicate 2
chr5_-_33236637 1.00 ENSDART00000085512
ENSDART00000144694
KN motif and ankyrin repeat domains 1b
chr19_+_15441022 1.00 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr7_+_67699178 1.00 ENSDART00000160086
zgc:162592
chr10_-_2943474 1.00 ENSDART00000188698
occludin a
chr25_+_5972690 1.00 ENSDART00000067517
si:ch211-11i22.4
chr10_-_1961576 0.99 ENSDART00000042441
teratocarcinoma-derived growth factor 1
chr2_-_15040345 0.99 ENSDART00000109657
si:dkey-10f21.4
chr4_-_858434 0.99 ENSDART00000006961
sine oculis binding protein homolog (Drosophila) b
chr9_+_22782027 0.98 ENSDART00000090816
replication timing regulatory factor 1
chr19_-_425145 0.98 ENSDART00000164905
dihydrouridine synthase 3-like (S. cerevisiae)
chr7_+_32901658 0.98 ENSDART00000115420
anoctamin 9b
chr2_+_21048661 0.97 ENSDART00000156876
ras responsive element binding protein 1b
chr6_-_55423220 0.97 ENSDART00000158929
cathepsin A
chr20_-_28404362 0.96 ENSDART00000055932
ENSDART00000188161
phosphatidylinositol glycan anchor biosynthesis, class H
chr17_-_24884966 0.94 ENSDART00000136142
UDP-galactose-4-epimerase
chr23_-_32156278 0.92 ENSDART00000157479
nuclear receptor subfamily 4, group A, member 1
chr18_-_127558 0.92 ENSDART00000149556
transient receptor potential cation channel, subfamily M, member 7
chr2_+_1988036 0.91 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr4_-_13614797 0.91 ENSDART00000138366
ENSDART00000165212
interferon regulatory factor 5
chr23_-_10175898 0.90 ENSDART00000146185
keratin 5
chr11_-_18283886 0.90 ENSDART00000019248
STIM activating enhance
chr20_-_1191910 0.88 ENSDART00000043218
ubiquitin-conjugating enzyme E2, J1
chr3_-_30888415 0.88 ENSDART00000124458
lysine methyltransferase 5C
chr13_+_7578111 0.87 ENSDART00000175431
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr21_-_4250682 0.87 ENSDART00000099389
DNL-type zinc finger
chr6_-_23002373 0.87 ENSDART00000037709
ENSDART00000170369
nucleolar protein 11
chr19_-_27339844 0.86 ENSDART00000052358
ENSDART00000148238
ENSDART00000147661
ENSDART00000137346
zinc ribbon domain containing 1
chr9_+_38888025 0.86 ENSDART00000148306
microtubule-associated protein 2
chr13_+_31716820 0.86 ENSDART00000034745
protein kinase C, eta, a
chr7_+_69187585 0.85 ENSDART00000160499
ENSDART00000166258
MARVEL domain containing 3
chr16_+_41060161 0.85 ENSDART00000141130
SREBF chaperone
chr19_-_27339670 0.85 ENSDART00000139323
zinc ribbon domain containing 1
chr20_-_20931197 0.85 ENSDART00000152726
BTB (POZ) domain containing 6b
chr14_+_41318881 0.85 ENSDART00000192137
XK, Kell blood group complex subunit-related, X-linked
chr11_-_43473824 0.85 ENSDART00000179561
transmembrane protein 63Bb
chr14_+_41318412 0.84 ENSDART00000064614
XK, Kell blood group complex subunit-related, X-linked
chr8_-_13735572 0.84 ENSDART00000139642
si:dkey-258f14.7
chr23_-_26488622 0.84 ENSDART00000168052
ENSDART00000169088
membrane associated guanylate kinase, WW and PDZ domain containing 3a
chr21_-_19919020 0.84 ENSDART00000147396
protein phosphatase 1, regulatory subunit 3B
chr5_-_11573490 0.84 ENSDART00000109577

chr8_+_13364950 0.83 ENSDART00000159760
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr19_+_15440841 0.83 ENSDART00000182329
lin-28 homolog A (C. elegans)
chr24_+_10898671 0.83 ENSDART00000106272
si:dkey-37o8.1
chr10_+_34001444 0.83 ENSDART00000149934
klotho
chr22_-_506522 0.82 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr8_+_2642384 0.82 ENSDART00000143242
nuclear apoptosis inducing factor 1
chr14_+_41318604 0.82 ENSDART00000167042
XK, Kell blood group complex subunit-related, X-linked
chr4_-_20232974 0.81 ENSDART00000193353
serine/threonine kinase 38 like
chr2_-_32237916 0.81 ENSDART00000141418
family with sequence similarity 49, member Ba
chr18_+_8917766 0.81 ENSDART00000145226
si:ch211-233h19.2
chr22_+_25249193 0.80 ENSDART00000171851
si:ch211-226h8.11
chr3_-_61494840 0.80 ENSDART00000101957
BAI1-associated protein 2-like 1b
chr10_+_15970 0.80 ENSDART00000040240
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr1_+_20593653 0.78 ENSDART00000132440
si:ch211-142c4.1
chr21_-_21526740 0.78 ENSDART00000142690
diablo, IAP-binding mitochondrial protein b
chr21_-_7928101 0.78 ENSDART00000151543
ENSDART00000114982
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
chr2_+_26237322 0.78 ENSDART00000030520
paralemmin 1b
chr5_+_57924611 0.77 ENSDART00000050949
B-cell translocation gene 4
chr11_+_6902946 0.77 ENSDART00000144006
CREB regulated transcription coactivator 1b
chr7_+_32695954 0.77 ENSDART00000184425
solute carrier family 39 (zinc transporter), member 13
chr5_-_23581355 0.76 ENSDART00000191869
CWC15 spliceosome-associated protein homolog (S. cerevisiae)
chr2_+_51796441 0.76 ENSDART00000165151
crystallin, gamma N1
chr19_+_791538 0.75 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr12_-_48312647 0.74 ENSDART00000114415
activating signal cointegrator 1 complex subunit 1
chr1_-_53625142 0.74 ENSDART00000166852
ubiquitin specific peptidase 34
chr14_-_6402769 0.73 ENSDART00000121552
solute carrier family 44 (choline transporter), member 1b
chr12_+_23866368 0.73 ENSDART00000188652
ENSDART00000192478
supervillin a
chr22_+_25248961 0.73 ENSDART00000143079
si:ch211-226h8.11
chr20_-_14114078 0.73 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr10_+_42589391 0.72 ENSDART00000067689
ENSDART00000075259
fibroblast growth factor receptor 1b
chr5_-_69948099 0.72 ENSDART00000034639
ENSDART00000191111
UDP glucuronosyltransferase 2 family, polypeptide A4
chr1_+_44173506 0.72 ENSDART00000170512
catenin (cadherin-associated protein), delta 1
chr3_+_26245731 0.72 ENSDART00000103734
ATPase family, AAA domain containing 5a
chr18_+_13248956 0.71 ENSDART00000080709
phospholipase C, gamma 2
chr11_-_25853212 0.71 ENSDART00000145655
transmembrane protein 51b
chr14_+_22457230 0.71 ENSDART00000019296
growth differentiation factor 9
chr14_-_25928541 0.71 ENSDART00000145850
GTPase activating protein (SH3 domain) binding protein 1
chr4_+_13901458 0.71 ENSDART00000137549
periphilin 1
chr23_-_18057270 0.71 ENSDART00000173385
zgc:92287
chr13_+_2448251 0.70 ENSDART00000188361
ARFGEF family member 3
chr6_-_31827597 0.70 ENSDART00000159400
receptor tyrosine kinase-like orphan receptor 1
chr1_-_40341306 0.70 ENSDART00000190649
mastermind-like transcriptional coactivator 3
chr17_-_8692722 0.69 ENSDART00000148931
ENSDART00000192891
C-terminal binding protein 2a
chr6_-_33685325 0.69 ENSDART00000181883
microtubule associated serine/threonine kinase 2
chr16_-_280255 0.69 ENSDART00000190252

chr10_+_42589707 0.69 ENSDART00000075269
fibroblast growth factor receptor 1b
chr19_-_17972734 0.69 ENSDART00000126298
integrator complex subunit 8
chr2_-_37280617 0.68 ENSDART00000190458
NAD kinase b
chr11_-_11791718 0.67 ENSDART00000180476
cell division cycle 6 homolog (S. cerevisiae)
chr7_-_55648336 0.67 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr17_-_37474689 0.67 ENSDART00000103980
cysteine-rich protein 2
chr10_-_38468847 0.67 ENSDART00000133914
glycerophosphodiester phosphodiesterase domain containing 5a
chr8_+_9699111 0.66 ENSDART00000111853
GRIP1 associated protein 1
chr18_+_6641542 0.66 ENSDART00000160379
C2 calcium-dependent domain containing 5
chr5_-_32338866 0.66 ENSDART00000017956
ENSDART00000047670
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr21_-_217589 0.66 ENSDART00000185017

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF4_id4_mespaa+mespab+mespba+mespbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.7 2.0 GO:0090008 hypoblast development(GO:0090008)
0.5 0.5 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.5 1.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.4 7.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.4 2.1 GO:0070254 mucus secretion(GO:0070254)
0.4 2.5 GO:0040016 embryonic cleavage(GO:0040016)
0.3 1.6 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.3 1.5 GO:0070986 left/right axis specification(GO:0070986)
0.3 0.9 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.3 3.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 0.9 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.3 0.9 GO:0072388 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.3 0.9 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.3 0.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 2.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 0.7 GO:0030237 female sex determination(GO:0030237)
0.2 5.0 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 2.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.6 GO:0061355 Wnt protein secretion(GO:0061355)
0.2 0.9 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.5 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.2 0.4 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.2 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 1.7 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 0.7 GO:0099563 modification of synaptic structure(GO:0099563)
0.2 0.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 0.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 0.5 GO:0042245 RNA repair(GO:0042245)
0.2 1.2 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.1 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 1.4 GO:0009303 rRNA transcription(GO:0009303)
0.1 1.4 GO:0030104 water homeostasis(GO:0030104)
0.1 0.7 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.1 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.7 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.6 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.9 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 1.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 1.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 1.0 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.5 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.6 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.3 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.3 GO:0035046 pronuclear migration(GO:0035046)
0.1 0.7 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.9 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.5 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.6 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.8 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.5 GO:0006953 acute-phase response(GO:0006953)
0.1 1.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.4 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.3 GO:0097384 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.5 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.2 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.1 0.4 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 2.0 GO:0048885 neuromast deposition(GO:0048885)
0.1 0.8 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.3 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 1.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.3 GO:0060074 synapse maturation(GO:0060074)
0.1 0.3 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.4 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.7 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 0.5 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.4 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 1.0 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.2 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.5 GO:0044209 AMP salvage(GO:0044209)
0.1 0.4 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 1.0 GO:0001840 neural plate development(GO:0001840)
0.1 0.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.2 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.1 0.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.3 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 1.2 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.0 GO:0061055 myotome development(GO:0061055)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 1.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.2 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.3 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.3 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 1.9 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.5 GO:0042554 superoxide anion generation(GO:0042554)
0.1 1.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 1.1 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.9 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 0.2 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.1 0.3 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 2.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 0.3 GO:1901021 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.2 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.2 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 1.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.1 GO:0010543 regulation of platelet activation(GO:0010543) regulation of platelet aggregation(GO:0090330)
0.1 0.4 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 0.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.8 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.5 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 1.4 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.3 GO:0032366 intracellular sterol transport(GO:0032366)
0.0 0.5 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.3 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 1.7 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.2 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 1.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.7 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 3.6 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.9 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.4 GO:0048599 oocyte development(GO:0048599)
0.0 0.4 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.2 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.0 1.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 3.6 GO:0008033 tRNA processing(GO:0008033)
0.0 1.0 GO:0050821 protein stabilization(GO:0050821)
0.0 0.3 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0006266 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.3 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.0 0.1 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.0 0.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 2.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.4 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.2 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.3 GO:0008585 female gonad development(GO:0008585)
0.0 0.1 GO:0032350 regulation of hormone metabolic process(GO:0032350)
0.0 0.1 GO:0043299 mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) regulation of mast cell activation involved in immune response(GO:0033006) Fc receptor signaling pathway(GO:0038093) leukocyte degranulation(GO:0043299) regulation of leukocyte degranulation(GO:0043300) mast cell degranulation(GO:0043303) regulation of mast cell degranulation(GO:0043304)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.3 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.4 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.2 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.4 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.3 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 2.3 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.1 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.3 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 1.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.6 GO:0048794 swim bladder development(GO:0048794)
0.0 0.8 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.7 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.2 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.5 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 1.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 4.3 GO:0006887 exocytosis(GO:0006887)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0090329 regulation of DNA-dependent DNA replication(GO:0090329)
0.0 0.5 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.0 GO:0070814 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 1.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.0 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 1.0 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.0 GO:0048940 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.0 0.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.3 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 2.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.6 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.1 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.2 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 1.0 GO:0045765 regulation of angiogenesis(GO:0045765)
0.0 0.1 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.6 GO:0051170 nuclear import(GO:0051170)
0.0 0.2 GO:0043491 protein kinase B signaling(GO:0043491)
0.0 0.0 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.5 1.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 1.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 4.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 1.6 GO:0001772 immunological synapse(GO:0001772)
0.2 3.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 3.1 GO:0042555 MCM complex(GO:0042555)
0.2 1.7 GO:0036449 microtubule minus-end(GO:0036449)
0.2 0.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 2.1 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 1.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.5 GO:0030904 retromer complex(GO:0030904)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 3.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.7 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.3 GO:0098536 deuterosome(GO:0098536)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.5 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.9 GO:0045095 keratin filament(GO:0045095)
0.1 5.6 GO:0005871 kinesin complex(GO:0005871)
0.1 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.8 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 2.2 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 6.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.1 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 1.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.6 GO:0043296 apical junction complex(GO:0043296)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 2.7 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 2.3 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.9 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 2.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.7 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 1.8 GO:0016607 nuclear speck(GO:0016607)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.3 GO:0010008 endosome membrane(GO:0010008)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.0 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.0 GO:0035804 structural constituent of egg coat(GO:0035804)
0.5 2.5 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.4 1.7 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.3 1.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.3 0.9 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.3 0.9 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3 0.9 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.3 2.8 GO:0005042 netrin receptor activity(GO:0005042)
0.3 2.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 1.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 5.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.4 GO:0032190 acrosin binding(GO:0032190)
0.2 0.6 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 2.7 GO:0070697 activin receptor binding(GO:0070697)
0.2 1.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 1.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 1.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 0.7 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 2.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 0.5 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.2 0.6 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.2 1.9 GO:0043495 protein anchor(GO:0043495)
0.2 1.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.6 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.6 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 1.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.5 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.6 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.5 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 2.6 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.5 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 2.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.4 GO:0032183 SUMO binding(GO:0032183)
0.1 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 1.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0004096 catalase activity(GO:0004096)
0.1 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 2.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.6 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.3 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.2 GO:0034246 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.8 GO:2001069 glycogen binding(GO:2001069)
0.1 1.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.3 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 0.2 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 2.2 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.0 1.3 GO:0022839 ion gated channel activity(GO:0022839)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 6.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.4 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.9 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 1.4 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.8 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.5 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.6 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.3 GO:0015296 anion:cation symporter activity(GO:0015296)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 6.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.7 GO:0032934 sterol binding(GO:0032934)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID ATM PATHWAY ATM pathway
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 ST GAQ PATHWAY G alpha q Pathway
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.7 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.8 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway