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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for CABZ01090890.1+atf6
Z-value: 1.04
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Transcription factors associated with CABZ01090890.1+atf6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| atf6 | dr11_v1_chr20_-_33864804_33864804 | -0.50 | 3.5e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of CABZ01090890.1+atf6
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | GO:0007030 | Golgi organization(GO:0007030) |
| 1.0 | 3.9 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.0 | 3.6 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 3.4 | GO:0016197 | endosomal transport(GO:0016197) |
| 0.1 | 3.1 | GO:0046466 | sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466) |
| 0.1 | 2.2 | GO:0019432 | triglyceride biosynthetic process(GO:0019432) |
| 0.0 | 2.2 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.1 | 2.0 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 2.0 | GO:0032200 | telomere maintenance(GO:0000723) telomere organization(GO:0032200) |
| 0.0 | 2.0 | GO:0006400 | tRNA modification(GO:0006400) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.5 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.2 | 3.6 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.0 | 3.1 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 2.2 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
| 0.1 | 2.2 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 2.0 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 1.9 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.2 | 1.8 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 1.8 | GO:0031201 | SNARE complex(GO:0031201) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 1.0 | 3.9 | GO:0004419 | hydroxymethylglutaryl-CoA lyase activity(GO:0004419) |
| 0.8 | 3.1 | GO:0008117 | sphinganine-1-phosphate aldolase activity(GO:0008117) |
| 0.0 | 2.8 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.3 | 2.4 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.1 | 2.2 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.1 | 2.1 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
| 0.3 | 2.0 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.6 | 1.8 | GO:0070905 | glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905) |
| 0.6 | 1.8 | GO:0046923 | ER retention sequence binding(GO:0046923) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.4 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.9 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.7 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 1.2 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.0 | 1.2 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 1.0 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 0.7 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.6 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.4 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.4 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 4.2 | REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |
| 0.1 | 3.8 | REACTOME REGULATION OF APOPTOSIS | Genes involved in Regulation of Apoptosis |
| 0.1 | 3.3 | REACTOME PRE NOTCH EXPRESSION AND PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
| 0.0 | 1.9 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.1 | 1.8 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 1.8 | REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT | Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript |
| 0.1 | 1.7 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 1.7 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.1 | 1.1 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |