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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for CABZ01090890.1+atf6

Z-value: 1.04

Motif logo

Transcription factors associated with CABZ01090890.1+atf6

Gene Symbol Gene ID Gene Info
ENSDARG00000012656 activating transcription factor 6
ENSDARG00000101369 ENSDARG00000101369

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
atf6dr11_v1_chr20_-_33864804_33864804-0.503.5e-02Click!

Activity profile of CABZ01090890.1+atf6 motif

Sorted Z-values of CABZ01090890.1+atf6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_24879003 2.42 ENSDART00000123147
zinc finger and BTB domain containing 8A
chr10_+_16036573 2.31 ENSDART00000188757
lamin B1
chr3_-_26184018 2.23 ENSDART00000191604
si:ch211-11k18.4
chr23_+_20431388 2.14 ENSDART00000132920
ENSDART00000102963
ENSDART00000109899
ENSDART00000140219
solute carrier family 35 (GDP-fucose transporter), member C2
chr10_+_16036246 2.12 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lamin B1
chr3_-_26183699 2.10 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr5_+_44846280 2.09 ENSDART00000084370
KN motif and ankyrin repeat domains 1a
chr4_+_23117557 2.07 ENSDART00000066909
solute carrier family 35, member E3
chr21_-_25295087 2.03 ENSDART00000087910
ENSDART00000147860
suppression of tumorigenicity 14 (colon carcinoma) b
chr25_-_36263115 2.02 ENSDART00000143046
ENSDART00000139002
dihydrouridine synthase 2
chr9_+_22780901 1.98 ENSDART00000110992
ENSDART00000143972
replication timing regulatory factor 1
chr17_-_24866727 1.97 ENSDART00000027957
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr10_-_28380919 1.96 ENSDART00000183409
ENSDART00000183105
ENSDART00000100207
ENSDART00000185392
ENSDART00000131220
B-cell translocation gene 3
chr1_+_36771954 1.95 ENSDART00000149022
Rho GTPase activating protein 10
chr17_-_24866964 1.91 ENSDART00000190601
ENSDART00000192547
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr5_-_1487256 1.87 ENSDART00000149599
ENSDART00000148411
ENSDART00000092087
ENSDART00000148464
golgin A2
chr6_-_1591002 1.85 ENSDART00000087039
zgc:123305
chr6_+_59176470 1.84 ENSDART00000161720
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_+_36772348 1.84 ENSDART00000109314
Rho GTPase activating protein 10
chr21_-_26677834 1.83 ENSDART00000077381
nuclear RNA export factor 1
chr3_+_24094581 1.77 ENSDART00000138270
ENSDART00000131509
coatomer protein complex, subunit zeta 2
chr18_+_39487486 1.74 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr6_-_29051773 1.74 ENSDART00000190508
ENSDART00000180191
ENSDART00000111682
ecotropic viral integration site 5b
chr18_+_7553950 1.71 ENSDART00000193420
ENSDART00000062143
zgc:77650
chr9_+_24192370 1.66 ENSDART00000003482
serine/threonine kinase 17b (apoptosis-inducing)
chr10_-_15879569 1.66 ENSDART00000136789
tight junction protein 2a (zona occludens 2)
chr22_+_18929412 1.66 ENSDART00000161598
ENSDART00000166650
ENSDART00000015951
ENSDART00000105392
ENSDART00000131131
basigin
chr3_+_36617024 1.61 ENSDART00000189957
pyridoxal-dependent decarboxylase domain containing 1
chr20_-_1191910 1.60 ENSDART00000043218
ubiquitin-conjugating enzyme E2, J1
chr9_+_21793565 1.56 ENSDART00000134915
REV1, polymerase (DNA directed)
chr3_+_36616713 1.53 ENSDART00000158284
pyridoxal-dependent decarboxylase domain containing 1
chr12_+_31783066 1.52 ENSDART00000105584
leucine rich repeat containing 59
chr4_-_27099224 1.51 ENSDART00000048383
cysteine-rich with EGF-like domains 2
chr1_-_36772147 1.49 ENSDART00000053369
protein arginine methyltransferase 9
chr5_-_48680580 1.49 ENSDART00000031194
LysM, putative peptidoglycan-binding, domain containing 3
chr18_+_8917766 1.49 ENSDART00000145226
si:ch211-233h19.2
chr23_+_20431140 1.48 ENSDART00000193950
solute carrier family 35 (GDP-fucose transporter), member C2
chr2_-_54387550 1.47 ENSDART00000097388
N-ethylmaleimide-sensitive factor attachment protein, gamma b
chr20_+_26940178 1.43 ENSDART00000190888
cell division cycle associated 4
chr20_-_46817223 1.42 ENSDART00000100336
estrogen-related receptor gamma b
chr22_+_10713713 1.42 ENSDART00000122349
hippocampus abundant transcript 1b
chr13_-_48431766 1.39 ENSDART00000159688
ENSDART00000171765
F-box protein 11a
chr15_-_43978141 1.37 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr1_+_38142354 1.36 ENSDART00000179352
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr23_-_29668286 1.36 ENSDART00000129248
calsyntenin 1
chr23_+_7692042 1.32 ENSDART00000018512
protein O-fucosyltransferase 1
chr11_+_24758967 1.30 ENSDART00000005616
ENSDART00000133481
arginyl aminopeptidase (aminopeptidase B)
chr22_+_2751887 1.30 ENSDART00000133652
si:dkey-20i20.11
chr3_-_2613990 1.25 ENSDART00000137102
si:dkey-217f16.6
chr10_-_3427589 1.24 ENSDART00000133452
ENSDART00000037183
transmembrane p24 trafficking protein 2
chr17_+_17764979 1.24 ENSDART00000105013
alkB homolog 1, histone H2A dioxygenase
chr9_+_50038347 1.21 ENSDART00000164712
cordon-bleu WH2 repeat protein-like 1b
chr15_+_24756860 1.21 ENSDART00000156424
ENSDART00000078035
carboxypeptidase D, a
chr5_-_30151815 1.20 ENSDART00000156048
zinc finger and BTB domain containing 44
chr20_+_41906960 1.18 ENSDART00000193460
centrosomal protein 85, like
chr9_-_27396404 1.14 ENSDART00000136412
ENSDART00000101401
testis expressed 30
chr15_-_31177324 1.14 ENSDART00000008854
WD repeat and SOCS box containing 1
chr17_+_50701748 1.13 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermitin family member 2
chr4_-_25515154 1.13 ENSDART00000186524
RNA binding motif protein 17
chr21_-_3613702 1.13 ENSDART00000139194
dymeclin
chr6_-_11812224 1.13 ENSDART00000150989
membrane-associated ring finger (C3HC4) 7
chr12_+_23991276 1.13 ENSDART00000153136
proteasome activator subunit 4b
chr4_+_17642731 1.13 ENSDART00000026509
CWF19-like 1, cell cycle control
chr3_+_54047342 1.10 ENSDART00000178486
olfactomedin 2a
chr3_-_18384501 1.09 ENSDART00000027630
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2a
chr10_+_15603082 1.08 ENSDART00000024450
zinc finger, AN1-type domain 5b
chr4_-_25515513 1.07 ENSDART00000142276
ENSDART00000044043
RNA binding motif protein 17
chr20_+_22799857 1.05 ENSDART00000058527
sec1 family domain containing 2
chr24_-_6024466 1.05 ENSDART00000040865
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr18_-_5248365 1.03 ENSDART00000082506
ENSDART00000082504
ENSDART00000097960
myelin expression factor 2
chr17_+_584369 1.03 ENSDART00000165143
chromosome 14 open reading frame 28
chr11_+_440305 1.02 ENSDART00000082517
RAB43, member RAS oncogene family
chr10_-_8672820 1.02 ENSDART00000080763
si:dkey-27b3.2
chr11_-_22916641 1.01 ENSDART00000080201
ENSDART00000154813
MDM4, p53 regulator
chr25_+_21098675 1.01 ENSDART00000079012
RAD52 homolog, DNA repair protein
chr16_-_5105295 1.00 ENSDART00000082071
ENSDART00000148955
ENSDART00000184700
ENSDART00000188127
branched chain keto acid dehydrogenase E1, beta polypeptide
chr13_+_33606739 1.00 ENSDART00000026464
cofilin 1 (non-muscle), like
chr20_+_22799641 0.97 ENSDART00000131132
sec1 family domain containing 2
chr1_+_10018466 0.96 ENSDART00000113551
tripartite motif containing 2b
chr12_+_47081783 0.94 ENSDART00000158568
5-methyltetrahydrofolate-homocysteine methyltransferase
chr4_-_73488406 0.94 ENSDART00000115002
si:ch73-266f23.1
chr3_-_47235997 0.94 ENSDART00000047071
transmembrane p24 trafficking protein 1a
chr4_-_3145359 0.93 ENSDART00000112210
pleckstrin homology domain containing, family A member 5
chr3_-_46410387 0.93 ENSDART00000156822
cell death-inducing p53 target 1
chr23_+_2703044 0.93 ENSDART00000182512
ENSDART00000105286
nuclear receptor coactivator 6
chr11_+_31380495 0.93 ENSDART00000185073
signal-induced proliferation-associated 1 like 2
chr6_+_58289335 0.92 ENSDART00000177399
Ral GTPase activating protein, beta subunit (non-catalytic)
chr15_+_47746176 0.92 ENSDART00000154481
ENSDART00000160914
StAR-related lipid transfer (START) domain containing 10
chr1_-_36771712 0.91 ENSDART00000148386
protein arginine methyltransferase 9
chr16_+_1228073 0.91 ENSDART00000109645

chr22_-_21676364 0.90 ENSDART00000183668
transducin like enhancer of split 2b
chr16_-_52540056 0.86 ENSDART00000188304

chr3_+_22984098 0.86 ENSDART00000043190
LSM12 homolog a
chr10_+_5689510 0.86 ENSDART00000183217
ENSDART00000172632
peptidylglycine alpha-amidating monooxygenase
chr11_-_42134968 0.82 ENSDART00000187115

chr1_+_59146298 0.81 ENSDART00000191885
ENSDART00000152747
G protein-coupled receptor 108
chr21_+_20391978 0.81 ENSDART00000180817
si:dkey-30k6.5
chr25_-_37084032 0.81 ENSDART00000025494
hypoxanthine phosphoribosyltransferase 1, like
chr7_-_29164818 0.80 ENSDART00000052348
exosome component 6
chr15_+_41815703 0.79 ENSDART00000059508
2-phosphoxylose phosphatase 1
chr21_-_3844322 0.78 ENSDART00000166652
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr25_+_21098990 0.78 ENSDART00000017488
RAD52 homolog, DNA repair protein
chr15_+_17100697 0.78 ENSDART00000183565
ENSDART00000123197
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr9_-_21459074 0.74 ENSDART00000136427
zinc finger, MYM-type 2
chr3_-_180860 0.73 ENSDART00000059956
ENSDART00000192506
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr19_-_29294457 0.73 ENSDART00000130815
ENSDART00000103437
E2F transcription factor 3
chr4_-_19693978 0.71 ENSDART00000100974
ENSDART00000040405
staphylococcal nuclease and tudor domain containing 1
chr7_+_13491452 0.71 ENSDART00000053535
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr19_-_10324573 0.71 ENSDART00000171795
U2 small nuclear RNA auxiliary factor 2b
chr6_+_49901465 0.71 ENSDART00000023515
charged multivesicular body protein 4Ba
chr22_+_1947494 0.70 ENSDART00000159121
si:dkey-15h8.15
chr14_-_45595711 0.70 ENSDART00000074038
SCY1-like, kinase-like 1
chr10_+_2582254 0.70 ENSDART00000016103
nucleoredoxin like 2
chr22_-_10641873 0.66 ENSDART00000064772
cytochrome b561 family, member D2
chr12_+_2995887 0.65 ENSDART00000189499
ENSDART00000182597
ENSDART00000184918
ENSDART00000182292
leucine rich repeat containing 45
chr18_-_34549721 0.64 ENSDART00000137101
ENSDART00000021880
signal sequence receptor, gamma
chr19_-_10324182 0.64 ENSDART00000151352
ENSDART00000151162
ENSDART00000023571
U2 small nuclear RNA auxiliary factor 2b
chr3_-_31845816 0.63 ENSDART00000157028
mitogen-activated protein kinase kinase kinase 3
chr14_-_4044545 0.62 ENSDART00000169527
sorting nexin 25
chr3_+_431208 0.62 ENSDART00000154296
ENSDART00000048733
si:ch73-308m11.1
si:dkey-167k11.5
chr18_+_619619 0.59 ENSDART00000159846
protogenin homolog a (Gallus gallus)
chr19_-_7540821 0.59 ENSDART00000143958
limb and CNS expressed 1 like
chr2_-_38225388 0.59 ENSDART00000146485
ENSDART00000128043
apoptotic chromatin condensation inducer 1a
chr12_-_13318944 0.58 ENSDART00000152201
ENSDART00000041394
ER membrane protein complex subunit 9
chr7_-_69352424 0.58 ENSDART00000170714
adaptor-related protein complex 1, gamma 1 subunit
chr13_+_36923052 0.55 ENSDART00000026313
thioredoxin-related transmembrane protein 1
chr8_-_5220125 0.54 ENSDART00000035676
BCL2 interacting protein 3 like a
chr3_-_57762247 0.54 ENSDART00000156522
calcium activated nucleotidase 1a
chr21_-_45382112 0.52 ENSDART00000151029
ENSDART00000151335
ENSDART00000151687
ENSDART00000075438
CDKN2A interacting protein N-terminal like
chr19_+_40248697 0.52 ENSDART00000151269
cyclin-dependent kinase 6
chr20_-_50014936 0.52 ENSDART00000148892
exostosin-like glycosyltransferase 3
chr22_+_1853999 0.51 ENSDART00000163288
zinc finger protein 1174
chr7_+_69449814 0.51 ENSDART00000109644
CTD nuclear envelope phosphatase 1b
chr6_+_27275716 0.49 ENSDART00000156434
ENSDART00000114347
selenocysteine lyase
chr12_+_8569685 0.48 ENSDART00000031676
nuclear receptor binding factor 2b
chr17_+_21102301 0.48 ENSDART00000035432
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr15_+_17100412 0.47 ENSDART00000154418
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr8_-_31919624 0.44 ENSDART00000085573
regulator of G protein signaling 7 binding protein a
chr8_-_65189 0.43 ENSDART00000168412
hydroxysteroid (17-beta) dehydrogenase 4
chr18_-_370286 0.43 ENSDART00000162633
si:ch211-79l17.1
chr3_+_41731527 0.41 ENSDART00000049007
ENSDART00000187866
carbohydrate (chondroitin 4) sulfotransferase 12a
chr17_-_28797395 0.41 ENSDART00000134735
sec1 family domain containing 1
chr4_-_16883051 0.41 ENSDART00000124627
serine/threonine kinase receptor associated protein
chr4_-_991043 0.40 ENSDART00000184706
N-acetylgalactosaminidase, alpha
chr5_-_27994679 0.39 ENSDART00000132740
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr16_-_36064143 0.39 ENSDART00000158358
ENSDART00000182584
serine/threonine kinase 40
chr6_-_50685862 0.39 ENSDART00000134146
metastasis suppressor 1
chr1_-_18592068 0.38 ENSDART00000082063
family with sequence similarity 114, member A1
chr13_-_28272299 0.38 ENSDART00000006393
T cell leukemia homeobox 1
chr22_+_17214389 0.38 ENSDART00000187083
ENSDART00000159468
ENSDART00000129109
ENSDART00000090107
nardilysin b (N-arginine dibasic convertase)
chr17_+_10090638 0.38 ENSDART00000169522
ENSDART00000160156
Sec23 homolog A, COPII coat complex component
chr11_-_7156620 0.37 ENSDART00000172823
ENSDART00000172879
ENSDART00000078916
small integral membrane protein 7
chr3_-_55537096 0.36 ENSDART00000123544
ENSDART00000188752
testis expressed 2
chr11_+_42482920 0.35 ENSDART00000160937
ADP-ribosylation factor 4a
chr13_-_22699024 0.35 ENSDART00000016946
glutamate dehydrogenase 1a
chr16_+_7985886 0.35 ENSDART00000126041
anoctamin 10a
chr17_-_277046 0.35 ENSDART00000182587

chr8_+_1843135 0.34 ENSDART00000141452
synaptosomal-associated protein 29
chr22_+_1786230 0.34 ENSDART00000169318
ENSDART00000164948
zinc finger protein 1154
chr4_-_27398385 0.32 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr17_+_30448452 0.32 ENSDART00000153939
lipin 1
chr5_-_41804398 0.31 ENSDART00000134492
alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
chr22_-_7809904 0.30 ENSDART00000182269
ENSDART00000097201
ENSDART00000138522
si:ch73-44m9.3
si:ch73-44m9.1
chr18_-_25855263 0.30 ENSDART00000042074
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba
chr16_-_46567136 0.29 ENSDART00000159180
si:dkey-152b24.7
chr22_+_32228882 0.28 ENSDART00000092082
mesencephalic astrocyte-derived neurotrophic factor
chr15_-_35212462 0.27 ENSDART00000043960
ArfGAP with FG repeats 1a
chr22_+_35275206 0.27 ENSDART00000112234
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr18_+_50523870 0.26 ENSDART00000151593
ubiquitin-like 7b (bone marrow stromal cell-derived)
chr15_-_43768776 0.25 ENSDART00000170398
glutamate receptor, metabotropic 5b
chr12_+_30653047 0.25 ENSDART00000148562
thrombospondin 2b
chr2_-_37465517 0.25 ENSDART00000139983
si:dkey-57k2.6
chr2_+_10063747 0.24 ENSDART00000143876
ENSDART00000014088
ENSDART00000134554
cytidylate kinase
chr11_+_42494531 0.24 ENSDART00000067604
ADP-ribosylation factor 4a
chr17_-_49438873 0.24 ENSDART00000004424
zinc finger protein 292a
chr21_-_40413191 0.24 ENSDART00000003221
nuclear speckle splicing regulatory protein 1
chr10_+_158590 0.24 ENSDART00000081982
potassium voltage-gated channel subfamily J member 15
chr9_-_42418470 0.22 ENSDART00000144353
calcitonin receptor-like a
chr25_-_35120691 0.22 ENSDART00000185663

chr1_+_26605065 0.22 ENSDART00000011645
coronin, actin binding protein, 2A
chr15_-_3534705 0.21 ENSDART00000158150
component of oligomeric golgi complex 6
chr25_+_16079913 0.21 ENSDART00000146350
fatty acyl CoA reductase 1
chr9_+_11379782 0.21 ENSDART00000190282
ENSDART00000007308
wingless-type MMTV integration site family, member 10a
chr11_-_3897067 0.19 ENSDART00000134858
ribophorin I
chr3_-_40162843 0.18 ENSDART00000129664
ENSDART00000025285
developmentally regulated GTP binding protein 2
chr16_-_22303130 0.18 ENSDART00000142181
si:dkey-92i15.4
chr13_-_2112450 0.16 ENSDART00000189343
family with sequence similarity 83, member B
chr8_-_2289264 0.16 ENSDART00000189397
plasminogen activator, tissue
chr15_-_25153352 0.16 ENSDART00000078095
ENSDART00000122184
vacuolar protein sorting 53 homolog (S. cerevisiae)
chr14_+_45970033 0.15 ENSDART00000047716
fermitin family member 3b
chr2_-_11504347 0.15 ENSDART00000019392
short chain dehydrogenase/reductase family 16C, member 5a
chr25_+_16080181 0.15 ENSDART00000061753
fatty acyl CoA reductase 1
chr15_-_37610434 0.15 ENSDART00000156856

chr22_-_4989803 0.14 ENSDART00000181359
ENSDART00000125265
ENSDART00000028634
ENSDART00000183294
calcium homeostasis endoplasmic reticulum protein
chr17_+_27134806 0.14 ENSDART00000151901
ribosomal protein S6 kinase a, polypeptide 1
chr15_+_8043751 0.14 ENSDART00000193701
cell adhesion molecule 2b
chr12_+_30653942 0.13 ENSDART00000179355
thrombospondin 2b
chr4_+_4509996 0.13 ENSDART00000028694
glucosamine (N-acetyl)-6-sulfatase a
chr19_+_4443285 0.12 ENSDART00000162683
trafficking protein particle complex 9
chr15_-_163586 0.11 ENSDART00000163597
septin-4

Network of associatons between targets according to the STRING database.

First level regulatory network of CABZ01090890.1+atf6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.6 1.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.6 1.8 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.4 1.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.3 1.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 1.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 1.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.3 0.8 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.3 1.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 1.0 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.2 1.2 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.2 1.3 GO:0006004 fucose metabolic process(GO:0006004)
0.2 1.4 GO:0032475 otolith formation(GO:0032475)
0.2 0.8 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.2 0.2 GO:0033632 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.9 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 0.8 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.5 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.4 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 1.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.0 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 1.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.3 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.1 0.3 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 3.1 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 1.9 GO:0001966 thigmotaxis(GO:0001966)
0.1 0.2 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.1 2.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 1.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.9 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.8 GO:0001573 ganglioside metabolic process(GO:0001573) ganglioside biosynthetic process(GO:0001574)
0.1 2.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.5 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 1.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.0 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.4 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 4.3 GO:0007030 Golgi organization(GO:0007030)
0.0 1.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.3 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.5 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 1.1 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008) muscle tissue morphogenesis(GO:0060415)
0.0 0.6 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.5 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 1.4 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.5 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 2.0 GO:0032200 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 3.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 2.0 GO:0006400 tRNA modification(GO:0006400)
0.0 0.6 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 2.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 1.7 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 1.0 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 3.4 GO:0016197 endosomal transport(GO:0016197)
0.0 2.0 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 1.0 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.1 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.3 1.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 3.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.2 1.8 GO:0070552 BRISC complex(GO:0070552)
0.2 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.4 GO:0089701 U2AF(GO:0089701)
0.1 2.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 1.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 2.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.7 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 2.0 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 4.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.7 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.9 GO:0030141 secretory granule(GO:0030141)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.8 3.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.6 1.8 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.6 1.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.6 1.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 2.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 1.5 GO:0035514 DNA demethylase activity(GO:0035514)
0.3 2.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.3 0.8 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.2 1.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 0.9 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.4 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.1 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.2 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 2.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.0 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 1.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 7.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 1.0 GO:0003697 single-stranded DNA binding(GO:0003697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 3.3 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 0.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 3.8 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.8 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 4.2 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.9 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits