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PRJNA207719: Tissue specific transcriptome profiling
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Results for znf143b
Z-value: 1.61
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Transcription factors associated with znf143b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| znf143b | dr11_v1_chr18_-_16937008_16937109 | 0.80 | 1.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr23_+_35714574 Show fit | 1.68 |
ENSDART00000164616
|
tubulin, alpha 1c |
|
| chr15_+_47161917 Show fit | 1.62 |
ENSDART00000167860
|
growth associated protein 43 |
|
| chr21_-_16399778 Show fit | 1.44 |
ENSDART00000136435
|
unc-5 netrin receptor Da |
|
| chr3_+_50310684 Show fit | 1.40 |
ENSDART00000112152
|
growth arrest-specific 7a |
|
| chr4_-_1324141 Show fit | 1.40 |
ENSDART00000180720
|
pleiotrophin |
|
| chr24_-_31843173 Show fit | 1.31 |
ENSDART00000185782
|
STEAP family member 2, metalloreductase |
|
| chr5_+_20148671 Show fit | 1.30 |
ENSDART00000143205
|
SV2 related protein a |
|
| chr6_-_48311 Show fit | 1.26 |
ENSDART00000131010
|
zgc:114175 |
|
| chr18_+_41495841 Show fit | 1.19 |
ENSDART00000098671
|
si:ch211-203b8.6 |
|
| chr25_-_13842618 Show fit | 1.17 |
ENSDART00000160258
|
mitogen-activated protein kinase 8 interacting protein 1a |
Network of associatons between targets according to the STRING database.
First level regulatory network of znf143b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.1 | 1.4 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.0 | 1.4 | GO:0051781 | positive regulation of cell division(GO:0051781) |
| 0.3 | 1.3 | GO:0015677 | copper ion import(GO:0015677) |
| 0.0 | 1.2 | GO:0046328 | regulation of JNK cascade(GO:0046328) |
| 0.1 | 1.1 | GO:0045920 | negative regulation of exocytosis(GO:0045920) |
| 0.0 | 1.1 | GO:0070830 | apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830) |
| 0.0 | 1.1 | GO:0003401 | axis elongation(GO:0003401) |
| 0.2 | 1.0 | GO:0072578 | neurotransmitter-gated ion channel clustering(GO:0072578) |
| 0.1 | 1.0 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | GO:0005884 | actin filament(GO:0005884) |
| 0.4 | 1.6 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 1.5 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 1.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 1.0 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 1.0 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.9 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 0.7 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 0.7 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.0 | 0.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.3 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 1.4 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.0 | 1.4 | GO:0008201 | heparin binding(GO:0008201) |
| 0.3 | 1.3 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.0 | 1.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.4 | 1.1 | GO:0050135 | NAD(P)+ nucleosidase activity(GO:0050135) |
| 0.1 | 1.1 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.0 | 1.1 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 1.0 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.1 | 1.0 | GO:0019211 | phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 1.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 1.1 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.8 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 0.6 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.5 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.5 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.9 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 0.7 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.6 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 0.5 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.0 | 0.4 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.4 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 0.4 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.4 | REACTOME FRS2 MEDIATED CASCADE | Genes involved in FRS2-mediated cascade |
| 0.0 | 0.3 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |