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PRJNA207719: Tissue specific transcriptome profiling
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Results for zbtb7b
Z-value: 1.35
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Transcription factors associated with zbtb7b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| zbtb7b | dr11_v1_chr16_-_54810464_54810464 | 0.37 | 5.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_77557279 Show fit | 4.56 |
ENSDART00000180113
|
|
|
| chr4_+_55758103 Show fit | 2.99 |
ENSDART00000185964
|
|
|
| chr4_-_77551860 Show fit | 1.57 |
ENSDART00000188176
|
|
|
| chr4_-_68569527 Show fit | 1.46 |
ENSDART00000192091
|
|
|
| chr4_-_77563411 Show fit | 1.39 |
ENSDART00000186841
|
|
|
| chr18_-_26715655 Show fit | 1.37 |
ENSDART00000181497
|
MALT paracaspase 3 |
|
| chr14_-_7207961 Show fit | 1.34 |
ENSDART00000167994
ENSDART00000166532 |
storkhead box 2b |
|
| chr1_-_59216197 Show fit | 1.23 |
ENSDART00000062426
|
lysophosphatidic acid receptor 2b |
|
| chr20_-_487783 Show fit | 1.20 |
ENSDART00000162218
|
collagen, type X, alpha 1b |
|
| chr3_-_61162750 Show fit | 1.10 |
ENSDART00000055064
|
parvalbumin 8 |
Network of associatons between targets according to the STRING database.
First level regulatory network of zbtb7b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0030048 | actin filament-based movement(GO:0030048) |
| 0.2 | 1.2 | GO:0003272 | endocardial cushion formation(GO:0003272) |
| 0.1 | 1.0 | GO:0046051 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 0.0 | 1.0 | GO:0050727 | regulation of inflammatory response(GO:0050727) |
| 0.1 | 0.9 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 0.8 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
| 0.1 | 0.7 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.1 | 0.7 | GO:0097369 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 0.6 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 0.5 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 1.2 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.7 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.0 | 0.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 0.5 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.1 | 0.4 | GO:0035060 | brahma complex(GO:0035060) |
| 0.0 | 0.4 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 0.3 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.2 | 1.3 | GO:0008118 | N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118) |
| 0.1 | 1.2 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.0 | 1.0 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 1.0 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.9 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.1 | 0.8 | GO:0004974 | leukotriene receptor activity(GO:0004974) |
| 0.0 | 0.8 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.2 | 0.7 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.1 | 0.7 | GO:0015385 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.5 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.4 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 0.3 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 0.1 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.9 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.6 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 0.6 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.5 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.0 | 0.4 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 0.3 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.3 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.0 | 0.2 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |