ISMARA results: zbtb47b+znf652

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PRJNA207719: Tissue specific transcriptome profiling

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Results for zbtb47b+znf652

Z-value: 1.57

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Transcription factors associated with zbtb47b+znf652

Gene Symbol	Gene ID	Gene Info
znf652 NCBI UniProt	ENSDARG00000062302	zinc finger protein 652
zbtb47b NCBI UniProt	ENSDARG00000079547	zinc finger and BTB domain containing 47b

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
znf652	dr11_v1_chr3_+_15773991_15773991	-0.87	5.4e-02	Click!
zbtb47b	dr11_v1_chr24_-_20599781_20599880	-0.87	5.7e-02	Click!

Activity profile of zbtb47b+znf652 motif

Sorted Z-values of zbtb47b+znf652 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr16_+_23913943 Show fit	1.80	ENSDART00000175404 ENSDART00000129525	apoa4b.1 NCBI UniProt Show fit	apolipoprotein A-IV b, tandem duplicate 1
chr16_-_31661536 Show fit	1.75	ENSDART00000169973	wu:fd46c06 NCBI UniProt Show fit	wu:fd46c06
chr16_-_31675669 Show fit	1.50	ENSDART00000168848 ENSDART00000158331	c1r NCBI UniProt Show fit	complement component 1, r subcomponent
chr5_+_37978501 Show fit	1.41	ENSDART00000012050	apoa1a NCBI UniProt Show fit	apolipoprotein A-Ia
chr21_+_27416284 Show fit	1.34	ENSDART00000077593 ENSDART00000108763	cfb NCBI UniProt Show fit	complement factor B
chr13_-_18637244 Show fit	1.31	ENSDART00000057869	mat1a NCBI UniProt Show fit	methionine adenosyltransferase I, alpha
chr5_-_69948099 Show fit	1.21	ENSDART00000034639 ENSDART00000191111	ugt2a4 NCBI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide A4
chr22_-_36856405 Show fit	1.20	ENSDART00000029588	kng1 NCBI UniProt Show fit	kininogen 1
chr8_-_30791089 Show fit	1.08	ENSDART00000147332	gstt1a NCBI UniProt Show fit	glutathione S-transferase theta 1a
chr14_+_32430982 Show fit	1.03	ENSDART00000017179 ENSDART00000123382 ENSDART00000075593	f9a NCBI UniProt Show fit	coagulation factor IXa

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb47b+znf652

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	2.1	GO:0072376	complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.0	1.9	GO:0007596	blood coagulation(GO:0007596)
0.0	1.5	GO:0031638	zymogen activation(GO:0031638)
0.3	1.4	GO:0010873	regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.2	1.3	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.2	1.2	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1	1.0	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2	0.9	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.9	GO:0042738	drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)

Showing 1 to 10 of 68 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	GO:0042627	chylomicron(GO:0042627)
0.0	1.1	GO:0005811	lipid particle(GO:0005811)
0.1	0.7	GO:0005826	actomyosin contractile ring(GO:0005826)
0.2	0.6	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0	0.6	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	0.5	GO:0071540	eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.1	0.4	GO:0031511	Mis6-Sim4 complex(GO:0031511)
0.1	0.4	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.4	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	0.3	GO:0034685	integrin alphav-beta6 complex(GO:0034685)

Showing 1 to 10 of 19 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	5.2	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	2.9	GO:0004364	glutathione transferase activity(GO:0004364)
0.3	1.4	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3	1.3	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
0.0	1.2	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	1.1	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.2	1.0	GO:0015105	arsenite transmembrane transporter activity(GO:0015105)
0.2	1.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.2	0.9	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.0	0.9	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)

Showing 1 to 10 of 62 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	1.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.

Showing 1 to 7 of 7 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.3	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	1.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.5	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription

Showing 1 to 10 of 14 entries

Results for zbtb47b+znf652

Z-value: 1.57

Motif logo

Transcription factors associated with zbtb47b+znf652

Activity-expression correlation:

Activity profile of zbtb47b+znf652 motif

Sorted Z-values of zbtb47b+znf652 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb47b+znf652

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: