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PRJNA207719: Tissue specific transcriptome profiling

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Results for zbtb14

Z-value: 5.04

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Transcription factors associated with zbtb14

Gene Symbol Gene ID Gene Info
ENSDARG00000098273 zinc finger and BTB domain containing 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb14dr11_v1_chr24_+_41989108_419891080.838.5e-02Click!

Activity profile of zbtb14 motif

Sorted Z-values of zbtb14 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_25649626 7.24 ENSDART00000146947
tachykinin 1
chr1_-_56223913 5.37 ENSDART00000019573
zgc:65894
chr25_+_14165447 5.12 ENSDART00000145387
SH3 and multiple ankyrin repeat domains 2
chr1_+_53321878 5.02 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr4_-_797831 4.86 ENSDART00000158970
ENSDART00000170012
microtubule-associated protein, RP/EB family, member 3b
chr16_-_43026273 4.70 ENSDART00000156820
ENSDART00000189080
si:dkey-7j14.5
chr23_+_44732863 4.35 ENSDART00000160044
ENSDART00000172268
ATPase Na+/K+ transporting subunit beta 2a
chr7_+_73332486 4.30 ENSDART00000174119
ENSDART00000092051
ENSDART00000192388

chr21_+_11468934 4.26 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr22_-_21150845 4.17 ENSDART00000027345
transmembrane protein 59-like
chr23_+_45611649 4.16 ENSDART00000169521
doublecortin-like kinase 2b
chr21_+_11468642 4.11 ENSDART00000041869
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr1_-_21409877 4.02 ENSDART00000102782
glutamate receptor, ionotropic, AMPA 2a
chr10_+_466926 4.00 ENSDART00000145220
ARVCF, delta catenin family member a
chr13_+_35746440 3.97 ENSDART00000187859
G protein-coupled receptor 75
chr2_+_42724404 3.83 ENSDART00000075392
brain abundant, membrane attached signal protein 1
chr4_+_5741733 3.79 ENSDART00000110243
POU class 3 homeobox 2a
chr16_-_43025885 3.60 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr4_-_5764255 3.58 ENSDART00000113864
failed axon connections homolog a
chr3_-_21280373 3.57 ENSDART00000003939
synaptogyrin 1a
chr14_-_2163454 3.47 ENSDART00000160123
ENSDART00000169653
protocadherin 2 alpha b 9
protocadherin 2 alpha c
chr24_+_32176155 3.47 ENSDART00000003745
vimentin
chr19_-_13733870 3.46 ENSDART00000177773
erythrocyte membrane protein band 4.1a
chr24_+_14713776 3.41 ENSDART00000134475
ganglioside induced differentiation associated protein 1
chr7_+_39624728 3.34 ENSDART00000173847
ENSDART00000173845
protein tyrosine phosphatase, non-receptor type 5
chr11_+_7324704 3.28 ENSDART00000031937
DIRAS family, GTP-binding RAS-like 1a
chr25_+_21324588 3.28 ENSDART00000151842
leucine rich repeat neuronal 3a
chr16_-_26074529 3.23 ENSDART00000148653
ENSDART00000148923
transmembrane protein 145
chr13_+_27073901 3.21 ENSDART00000146227
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr18_+_42970208 3.14 ENSDART00000084454
nectin cell adhesion molecule 1b
chr14_-_9199968 3.12 ENSDART00000146113
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr22_-_372723 3.11 ENSDART00000112895
si:zfos-1324h11.5
chr16_+_45456066 3.04 ENSDART00000093365
synaptic Ras GTPase activating protein 1b
chr24_+_5840748 3.02 ENSDART00000139191
transient receptor potential cation channel, subfamily C, member 1
chr18_-_5692292 3.01 ENSDART00000121503
complexin 3b
chr24_+_5840258 3.00 ENSDART00000087034
transient receptor potential cation channel, subfamily C, member 1
chr7_+_48288762 2.99 ENSDART00000083569
ornithine decarboxylase antizyme 2b
chr1_-_8428736 2.98 ENSDART00000138435
ENSDART00000121823
synaptogyrin 3b
chr19_-_5254699 2.93 ENSDART00000081951
syntaxin 1B
chr13_+_30054996 2.92 ENSDART00000110061
ENSDART00000186045
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr14_-_34276574 2.91 ENSDART00000021437
glutamate receptor, ionotropic, AMPA 1a
chr5_+_63668735 2.91 ENSDART00000134261
ENSDART00000097330
dynamin 1b
chr8_+_26868105 2.90 ENSDART00000005337
ribosomal modification protein rimK-like family member A
chr3_+_17744339 2.86 ENSDART00000132622
zinc finger protein 385C
chr2_+_46032678 2.85 ENSDART00000184382
ENSDART00000125971
glypican 1b
chr2_+_26179096 2.81 ENSDART00000024662
phospholipid phosphatase related 3a
chr20_-_40451115 2.80 ENSDART00000075092
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr19_-_25301711 2.79 ENSDART00000175739
regulating synaptic membrane exocytosis 3
chr13_-_27767330 2.77 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
regulating synaptic membrane exocytosis 1a
chr20_+_50852356 2.76 ENSDART00000167517
ENSDART00000168396
gephyrin b
chr5_-_22952156 2.75 ENSDART00000111146
si:ch211-26b3.4
chr7_-_52334429 2.73 ENSDART00000187372

chr25_-_22639133 2.73 ENSDART00000073583
immunoglobulin superfamily containing leucine-rich repeat 2
chr20_+_474288 2.66 ENSDART00000026794
5'-nucleotidase domain containing 1
chr10_-_13772847 2.64 ENSDART00000145103
ENSDART00000184491
ciliary neurotrophic factor receptor
chr10_-_15405564 2.64 ENSDART00000020665
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr1_-_20911297 2.62 ENSDART00000078271
carboxypeptidase E
chr3_-_36944749 2.62 ENSDART00000154501
contactin associated protein 1
chr13_+_30055171 2.61 ENSDART00000143581
ENSDART00000132027
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_27223827 2.59 ENSDART00000185138
autism susceptibility candidate 2a
chr2_-_44720551 2.58 ENSDART00000146380
MAP6 domain containing 1
chr5_-_21030934 2.57 ENSDART00000133461
ENSDART00000098667
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr1_-_38709551 2.55 ENSDART00000128794
glycoprotein M6Ab
chr3_-_36115339 2.55 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
RAB11 family interacting protein 4 (class II) a
chr7_+_32722227 2.53 ENSDART00000126565
si:ch211-150g13.3
chr7_+_74141297 2.53 ENSDART00000164992
RNA binding protein with multiple splicing
chr5_-_34185497 2.53 ENSDART00000146321
fibrinogen C domain containing 1
chr25_-_3979583 2.53 ENSDART00000124749
myelin regulatory factor
chr8_+_47897734 2.50 ENSDART00000140266
mitofusin 2
chr4_-_133492 2.47 ENSDART00000171845
G protein-coupled receptor 19
chr17_+_50127648 2.43 ENSDART00000156460
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr23_-_44226556 2.42 ENSDART00000149115
zgc:158659
chr25_+_4837915 2.42 ENSDART00000168016
guanine nucleotide binding protein (G protein), beta 5a
chr21_-_25573064 2.41 ENSDART00000134310

chr17_-_45254585 2.39 ENSDART00000185507
ENSDART00000172080
tau tubulin kinase 2a
chr19_+_1184878 2.38 ENSDART00000163539
scratch family zinc finger 1a
chr14_-_4682114 2.37 ENSDART00000014454
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr20_-_33790003 2.34 ENSDART00000020183
family with sequence similarity 102, member B, b
chr19_-_307246 2.33 ENSDART00000145916
leucine rich repeat and Ig domain containing 4a
chr2_-_54039293 2.33 ENSDART00000166013
abhydrolase domain containing 8a
chr13_-_31470439 2.32 ENSDART00000076574
reticulon 1a
chr6_-_11780070 2.30 ENSDART00000151195
membrane-associated ring finger (C3HC4) 7
chr22_-_12160283 2.29 ENSDART00000146785
ENSDART00000128176
transmembrane protein 163b
chr8_+_48603398 2.23 ENSDART00000074900
zgc:195023
chr17_-_3986236 2.21 ENSDART00000188794
ENSDART00000160830
si:ch1073-140o9.2
chr22_-_29586608 2.18 ENSDART00000059869
adrenoceptor alpha 2A
chr6_-_13308813 2.17 ENSDART00000065372
potassium inwardly-rectifying channel, subfamily J, member 3b
chr21_+_39423974 2.16 ENSDART00000031470
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr23_+_45611980 2.14 ENSDART00000181582
doublecortin-like kinase 2b
chr22_+_4488454 2.14 ENSDART00000170620
cortexin 1
chr12_+_21299338 2.07 ENSDART00000074540
ENSDART00000133188
carbonic anhydrase Xa
chr12_+_12112384 2.06 ENSDART00000152431
glutamate receptor, ionotropic, delta 1b
chr24_-_25673405 2.05 ENSDART00000186081
ENSDART00000110241
ENSDART00000142351
connector enhancer of kinase suppressor of Ras 2a
chr2_-_24462277 2.05 ENSDART00000033922
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a
chr17_-_24717925 2.03 ENSDART00000153725
si:ch211-15d5.11
chr7_+_14632157 2.03 ENSDART00000161264
neurotrophic tyrosine kinase, receptor, type 3b
chr3_+_32789605 2.03 ENSDART00000171895
TBC1 domain family, member 10b
chr14_+_11103718 2.01 ENSDART00000161311
neurite extension and migration factor b
chr7_-_49594995 2.00 ENSDART00000174161
ENSDART00000109147
BR serine/threonine kinase 2b
chr9_+_53707240 1.99 ENSDART00000171490
si:ch211-199f5.1
chr3_-_1204341 1.98 ENSDART00000089646
family with sequence similarity 234, member B
chr4_+_2482046 1.98 ENSDART00000103371
zinc finger, DHHC-type containing 17
chr5_-_31712399 1.96 ENSDART00000141328
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr17_-_20287530 1.94 ENSDART00000078703
ENSDART00000191289
adducin 3 (gamma) b
chr12_+_26621906 1.92 ENSDART00000158440
ENSDART00000046959
Rho GTPase activating protein 12b
chr11_+_15931188 1.91 ENSDART00000165768
ENSDART00000081098
dorsal inhibitory axon guidance protein
chr11_-_37589293 1.86 ENSDART00000172989
bassoon (presynaptic cytomatrix protein) b
chr22_+_3045495 1.85 ENSDART00000164061

chr10_-_25069155 1.84 ENSDART00000078226
ENSDART00000181941
melatonin receptor 1Bb
chr22_+_38978084 1.83 ENSDART00000025482
Rho guanine nucleotide exchange factor (GEF) 3
chr1_-_22834824 1.82 ENSDART00000043556
LIM domain binding 2b
chr7_-_47850702 1.82 ENSDART00000109511
si:ch211-186j3.6
chr25_-_3979288 1.82 ENSDART00000157117
myelin regulatory factor
chr24_+_39227519 1.81 ENSDART00000184611
ENSDART00000193494
ENSDART00000190728
ENSDART00000168705
si:ch73-103b11.2
chr1_+_20635190 1.78 ENSDART00000145418
ENSDART00000148518
ENSDART00000139461
ENSDART00000102969
ENSDART00000166479
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr18_-_44527124 1.78 ENSDART00000189471
amyloid beta (A4) precursor-like protein 2
chr10_-_21054059 1.78 ENSDART00000139733
protocadherin 1a
chr1_-_50859053 1.77 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr14_-_2400668 1.76 ENSDART00000172717
ENSDART00000182882
si:ch73-233f7.1
chr18_-_44526940 1.75 ENSDART00000077125
amyloid beta (A4) precursor-like protein 2
chr12_-_30032188 1.74 ENSDART00000042514
attractin-like 1b
chr24_+_16393302 1.74 ENSDART00000188670
ENSDART00000081759
ENSDART00000177790
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr13_+_29773153 1.74 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
paired box 2a
chr24_+_4977862 1.74 ENSDART00000114537
zic family member 4
chr17_+_51764310 1.74 ENSDART00000157171
si:ch211-168d23.3
chr22_-_22416337 1.72 ENSDART00000142947
ENSDART00000089569
calmodulin regulated spectrin-associated protein family, member 2a
chr19_+_4463389 1.72 ENSDART00000168805
potassium channel, subfamily K, member 9
chr19_+_14059349 1.71 ENSDART00000166230
trophoblast glycoprotein a
chr24_-_39354829 1.70 ENSDART00000169108
potassium inwardly-rectifying channel, subfamily J, member 12a
chr18_+_16125852 1.69 ENSDART00000061106
basic helix-loop-helix family, member e41
chr14_+_8947282 1.67 ENSDART00000047993
ribosomal protein S6 kinase a, like
chr16_+_32559821 1.67 ENSDART00000093250
POU class 3 homeobox 2b
chr14_-_25577094 1.65 ENSDART00000163669
complexin 2
chr11_+_29856032 1.65 ENSDART00000079150
gastrin-releasing peptide receptor
chr2_+_40294313 1.64 ENSDART00000037292
eph receptor A4b
chr1_-_23157583 1.63 ENSDART00000144208
adhesion G protein-coupled receptor L3.1
chr16_+_52771199 1.63 ENSDART00000111383
brain and acute leukemia, cytoplasmic a
chr13_-_29421331 1.62 ENSDART00000150228
choline O-acetyltransferase a
chr24_-_35699595 1.62 ENSDART00000167990
microtubule-associated protein, RP/EB family, member 2
chr12_+_1398404 1.62 ENSDART00000026303
RAS, dexamethasone-induced 1
chr2_-_44398611 1.59 ENSDART00000146192
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1a
chr3_-_21348478 1.59 ENSDART00000114906
family with sequence similarity 171, member A2a
chr2_-_9259283 1.59 ENSDART00000133092
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5a
chr24_-_6501211 1.59 ENSDART00000186241
ENSDART00000109040
ENSDART00000136154
G protein-coupled receptor 158a
chr2_-_30324610 1.58 ENSDART00000185422
junctophilin 1b
chr4_-_9810999 1.58 ENSDART00000146858
si:dkeyp-27e10.3
chr1_-_47771742 1.57 ENSDART00000101079
neuralized E3 ubiquitin protein ligase 1Aa
chr5_+_28973264 1.55 ENSDART00000005638
syntaxin binding protein 1b
chr12_+_47698356 1.55 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr1_-_57280585 1.54 ENSDART00000152220
si:dkey-27j5.5
chr2_+_38742338 1.54 ENSDART00000177290
capping protein regulator and myosin 1 linker 3
chr9_-_14504834 1.53 ENSDART00000056103
neuropilin 2b
chr14_-_48588422 1.52 ENSDART00000161147
si:ch211-154c21.1
chr10_+_19310688 1.50 ENSDART00000141364
leucine rich repeat transmembrane neuronal 4 like 1
chr25_-_20381107 1.50 ENSDART00000067454
potassium channel tetramerization domain containing 15a
chr8_+_23916647 1.50 ENSDART00000143152
copine Va
chr20_+_18209895 1.50 ENSDART00000111063
potassium channel tetramerization domain containing 1
chr10_-_25328814 1.49 ENSDART00000123820
transmembrane protein 135
chr9_+_21843915 1.48 ENSDART00000101977
potassium channel tetramerisation domain containing 12.1
chr25_-_20381271 1.48 ENSDART00000142665
potassium channel tetramerization domain containing 15a
chr20_+_38322444 1.47 ENSDART00000161741
ENSDART00000132241
ENSDART00000148936
ENSDART00000149623
stum, mechanosensory transduction mediator homolog
chr4_-_2196798 1.47 ENSDART00000110178
ENSDART00000149330
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr5_+_28972935 1.46 ENSDART00000193274
syntaxin binding protein 1b
chr4_-_3145359 1.46 ENSDART00000112210
pleckstrin homology domain containing, family A member 5
chr12_+_21298317 1.44 ENSDART00000178562
carbonic anhydrase Xa
chr24_+_41931585 1.42 ENSDART00000130310
erythrocyte membrane protein band 4.1-like 3a
chr18_-_6856380 1.41 ENSDART00000175747
protein phosphatase 6, regulatory subunit 2b
chr9_+_8929764 1.40 ENSDART00000102562
ankyrin repeat domain 10b
chr14_-_9056066 1.35 ENSDART00000139669
ENSDART00000138758
ENSDART00000041099
synaptobrevin-like 1
chr14_-_7306983 1.35 ENSDART00000158914
si:ch211-51f19.1
chr5_+_64277604 1.35 ENSDART00000111282
quiescin Q6 sulfhydryl oxidase 2
chr22_-_29922872 1.35 ENSDART00000020249
dual specificity phosphatase 5
chr10_+_23060391 1.35 ENSDART00000079711
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr12_-_7607114 1.34 ENSDART00000158095
solute carrier family 16, member 9b
chr20_-_35246150 1.33 ENSDART00000090549
frizzled class receptor 3a
chr24_-_35699444 1.33 ENSDART00000166567
microtubule-associated protein, RP/EB family, member 2
chr17_-_2535682 1.30 ENSDART00000155227
coiled-coil domain containing 9B
chr10_-_37075361 1.30 ENSDART00000132023
myosin XVIIIAa
chr6_-_957830 1.30 ENSDART00000090019
ENSDART00000184286
zinc finger E-box binding homeobox 2b
chr7_+_73593814 1.29 ENSDART00000110544
zinc finger protein 219
chr18_-_6855991 1.29 ENSDART00000135206
protein phosphatase 6, regulatory subunit 2b
chr18_-_46882056 1.28 ENSDART00000108574
GRAM domain containing 1Bb
chr23_-_10914275 1.28 ENSDART00000112965
PDZ domain containing RING finger 3a
chr4_-_12007404 1.28 ENSDART00000092250
BTB (POZ) domain containing 11a
chr17_+_15983247 1.28 ENSDART00000154275
calmin
chr1_+_9004719 1.28 ENSDART00000006211
ENSDART00000137211
protein kinase C, beta a
chr24_-_27879182 1.27 ENSDART00000105778
heparan sulfate 6-O-sulfotransferase 1b
chr15_+_36941490 1.27 ENSDART00000172664
kirre like nephrin family adhesion molecule 3, like
chr10_+_45248326 1.25 ENSDART00000159797
zinc finger, MIZ-type containing 2
chr25_-_12203952 1.24 ENSDART00000158204
ENSDART00000091727
neurotrophic tyrosine kinase, receptor, type 3a
chr24_-_38816725 1.24 ENSDART00000063231
noggin 2
chr22_+_28803739 1.24 ENSDART00000129476
ENSDART00000189726
tumor protein p53 binding protein, 2b
chr7_-_19369002 1.24 ENSDART00000165680
netrin 4
chr24_+_4978055 1.23 ENSDART00000045813
zic family member 4
chr6_+_4539953 1.22 ENSDART00000025031
POU class 4 homeobox 1
chr14_-_9355177 1.20 ENSDART00000138535
family with sequence similarity 46, member D
chr25_+_3677650 1.20 ENSDART00000154348
prion protein, related sequence 3
chr24_+_35881124 1.20 ENSDART00000143015
kelch-like family member 14
chr7_-_24236364 1.19 ENSDART00000010124
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr19_+_41075488 1.18 ENSDART00000138687
protein phosphatase 1, regulatory subunit 9A

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.0 3.1 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.9 2.8 GO:0072579 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.9 2.6 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.9 7.8 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.8 4.2 GO:0061551 trigeminal ganglion development(GO:0061551)
0.6 2.9 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.5 1.6 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.5 2.0 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.5 4.3 GO:0043217 myelin maintenance(GO:0043217)
0.5 2.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.5 8.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 1.8 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.4 2.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.4 1.7 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.4 3.0 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.4 2.6 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.4 5.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.4 1.1 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176) regulation of apoptotic cell clearance(GO:2000425)
0.3 1.3 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.3 1.0 GO:0030186 melatonin metabolic process(GO:0030186)
0.3 1.7 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.3 2.0 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.3 1.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 11.7 GO:0046847 filopodium assembly(GO:0046847)
0.3 0.9 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.3 1.4 GO:1904861 excitatory synapse assembly(GO:1904861)
0.3 2.6 GO:0032288 myelin assembly(GO:0032288)
0.3 1.5 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.3 5.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.2 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.2 4.4 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 1.7 GO:0021588 cerebellum formation(GO:0021588)
0.2 2.8 GO:0048899 anterior lateral line development(GO:0048899)
0.2 1.6 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.2 1.0 GO:0060544 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.2 1.0 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.2 1.5 GO:0051013 microtubule severing(GO:0051013)
0.2 9.6 GO:0036269 swimming behavior(GO:0036269)
0.2 1.9 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 3.3 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.2 2.2 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.2 0.8 GO:0045056 transcytosis(GO:0045056)
0.2 0.9 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.2 1.7 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.2 1.7 GO:0030431 sleep(GO:0030431)
0.2 2.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.7 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.7 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.5 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 2.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.8 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.9 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 3.0 GO:0006595 polyamine metabolic process(GO:0006595)
0.1 1.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.3 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 4.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 4.7 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.4 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 2.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 2.6 GO:0021884 forebrain neuron development(GO:0021884)
0.1 2.4 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 1.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.6 GO:0030728 ovulation(GO:0030728)
0.1 2.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 3.4 GO:0060037 pharyngeal system development(GO:0060037)
0.1 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 0.3 GO:0097037 heme export(GO:0097037)
0.1 2.3 GO:0006829 zinc II ion transport(GO:0006829)
0.1 1.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 0.4 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.2 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.1 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 2.5 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.7 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 2.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 3.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 1.3 GO:0072176 pronephric duct development(GO:0039022) nephric duct development(GO:0072176)
0.1 1.3 GO:0060030 dorsal convergence(GO:0060030)
0.1 4.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 2.5 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.3 GO:0031053 primary miRNA processing(GO:0031053)
0.1 7.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 3.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.3 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 2.7 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 1.5 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.1 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.1 4.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 2.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.2 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.4 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.4 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 5.9 GO:0048675 axon extension(GO:0048675)
0.0 1.3 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 2.3 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 2.0 GO:0001885 endothelial cell development(GO:0001885)
0.0 2.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.3 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.7 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.6 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 1.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.5 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 1.0 GO:0007416 synapse assembly(GO:0007416)
0.0 1.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.1 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 5.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.1 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 1.1 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 5.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.0 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0001706 endoderm formation(GO:0001706)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 1.3 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:1901571 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.0 1.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 1.0 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.0 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 1.6 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 1.9 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0072380 TRC complex(GO:0072380)
0.5 7.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 2.4 GO:0030314 junctional membrane complex(GO:0030314)
0.4 4.4 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.4 5.9 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.4 1.8 GO:1990071 TRAPPII protein complex(GO:1990071)
0.3 2.6 GO:0033010 paranodal junction(GO:0033010)
0.3 7.8 GO:0035371 microtubule plus-end(GO:0035371)
0.3 7.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.2 4.7 GO:0043195 terminal bouton(GO:0043195)
0.2 2.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 6.6 GO:0031594 neuromuscular junction(GO:0031594)
0.2 2.6 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.7 GO:1990752 microtubule end(GO:1990752)
0.2 0.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 6.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 2.9 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 2.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 3.8 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.1 0.5 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 2.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 3.5 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.1 GO:0043679 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.1 4.1 GO:0030496 midbody(GO:0030496)
0.1 0.8 GO:0030904 retromer complex(GO:0030904)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.1 8.7 GO:0099572 postsynaptic specialization(GO:0099572)
0.1 2.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 8.9 GO:0034703 cation channel complex(GO:0034703)
0.0 1.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0046930 pore complex(GO:0046930)
0.0 7.6 GO:0005911 cell-cell junction(GO:0005911)
0.0 4.5 GO:0030424 axon(GO:0030424)
0.0 2.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0008278 cohesin complex(GO:0008278)
0.0 0.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 8.1 GO:0005874 microtubule(GO:0005874)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 1.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.4 GO:0031201 SNARE complex(GO:0031201)
0.0 2.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 6.3 GO:0043005 neuron projection(GO:0043005)
0.0 1.3 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 18.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 5.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 8.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 1.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
1.0 2.9 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.9 2.8 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.7 3.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.5 3.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 2.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.5 6.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.4 1.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.4 2.8 GO:0030274 LIM domain binding(GO:0030274)
0.4 7.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.4 2.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.4 3.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 1.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.3 7.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 0.9 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.3 1.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 2.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 8.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 2.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 2.4 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.2 4.4 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 1.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 1.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 0.8 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 1.0 GO:0015288 porin activity(GO:0015288)
0.2 1.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 1.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 0.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 2.4 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.2 0.7 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 1.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 1.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 2.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.2 1.1 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.4 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 2.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.7 GO:0030507 spectrin binding(GO:0030507)
0.1 1.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 2.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 3.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 2.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.6 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 2.1 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 2.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 2.5 GO:0031267 small GTPase binding(GO:0031267)
0.1 5.6 GO:0044325 ion channel binding(GO:0044325)
0.1 1.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.5 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 3.7 GO:0019003 GDP binding(GO:0019003)
0.1 2.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.5 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 4.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 1.1 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.9 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 4.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 1.2 GO:0002039 p53 binding(GO:0002039)
0.1 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 1.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 3.0 GO:0019905 syntaxin binding(GO:0019905)
0.1 2.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 6.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.3 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 4.5 GO:0045296 cadherin binding(GO:0045296)
0.0 2.7 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 3.5 GO:0008201 heparin binding(GO:0008201)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 11.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 3.5 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 7.2 GO:0003924 GTPase activity(GO:0003924)
0.0 2.5 GO:0060090 binding, bridging(GO:0060090)
0.0 0.8 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 4.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 9.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.5 PID AURORA B PATHWAY Aurora B signaling
0.1 1.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 1.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 1.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 2.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 2.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 2.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 2.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 11.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 0.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.8 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 3.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.1 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.8 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.1 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production